Arachidonate epoxygenase / epoxide hydrolase
Pathways in the Arachidonate epoxygenase / epoxide hydrolase SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Arachidonate epoxygenase / epoxide hydrolase | WikiPathways |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | GSTP1 | Glutathione S-Transferase Pi 1 | Protein Coding | 1 |
| 2 | EPHX2 | Epoxide Hydrolase 2 | Protein Coding | 1 |
| 3 | CYP2J2 | Cytochrome P450 Family 2 Subfamily J Member 2 | Protein Coding | 1 |
| 4 | CYP2C9 | Cytochrome P450 Family 2 Subfamily C Member 9 | Protein Coding | 1 |
| 5 | CYP2C8 | Cytochrome P450 Family 2 Subfamily C Member 8 | Protein Coding | 1 |
| 6 | COX5A | Cytochrome C Oxidase Subunit 5A | Protein Coding | 1 |
| 7 | COX8A | Cytochrome C Oxidase Subunit 8A | Protein Coding | 1 |
Disorders associated with Arachidonate epoxygenase / epoxide hydrolase SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Cox deficiency, benign infantile mitochondrial myopathy | Enrichment | COX5A, COX8A | 4.68 |
| 2 | Drug metabolism, altered, cyp2c8-related | Enrichment | CYP2C8 | 3.29 |
| 3 | Mitochondrial complex iv deficiency, nuclear type 20 | Enrichment | COX5A | 3.29 |
| 4 | Mitochondrial complex iv deficiency, nuclear type 15 | Enrichment | COX8A | 3.29 |
| 5 | Kala-azar 2 | Enrichment | GSTP1 | 2.99 |
| 6 | Coumarin resistance | Enrichment | CYP2C9 | 2.81 |
| 7 | Hypercholesterolemia, familial, 1 | Enrichment | EPHX2 | 2.17 |
| 8 | Familial hypercholesterolemia | Enrichment | EPHX2 | 2.11 |
| 9 | Mitochondrial complex iv deficiency, nuclear type 1 | Enrichment | COX8A | 1.95 |
