Arf6 signaling events

No Pathway Network information available for Arf6 signaling events

Pathways in the Arf6 signaling events SuperPath

#	Name	Source	Genes
1	Arf6 signaling events	PubChem	ACAP1 ACAP2 ADAP1 ADRB2 AGTR1 ARAP2 ARF6 ARRB2 CYTH2 CYTH3 EFNA1 EGF EGFR EPHA2 FBXO8 GIT1 GNAQ GULP1 HGF IPCEF1 IQSEC1 ITGA2B ITGB3 KIF13B LHCGR MET NCK1 PSD PXN SRC TSHR USP6 (see all 32) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACAP2	ArfGAP With Coiled-Coil, Ankyrin Repeat And PH Domains 2	Protein Coding	1
2	ARAP2	ArfGAP With RhoGAP Domain, Ankyrin Repeat And PH Domain 2	Protein Coding	1
3	IQSEC1	IQ Motif And Sec7 Domain ArfGEF 1	Protein Coding	1
4	GULP1	GULP PTB Domain Containing Engulfment Adaptor 1	Protein Coding	1
5	FBXO8	F-Box Protein 8	Protein Coding	1
6	IPCEF1	Interaction Protein For Cytohesin Exchange Factors 1	Protein Coding	1
7	KIF13B	Kinesin Family Member 13B	Protein Coding	1
8	USP6	Ubiquitin Specific Peptidase 6	Protein Coding	1
9	PSD	Pleckstrin And Sec7 Domain Containing	Protein Coding	1
10	CYTH3	Cytohesin 3	Protein Coding	1
11	ACAP1	ArfGAP With Coiled-Coil, Ankyrin Repeat And PH Domains 1	Protein Coding	1
12	EPHA2	EPH Receptor A2	Protein Coding	1
13	EFNA1	Ephrin A1	Protein Coding	1
14	CYTH2	Cytohesin 2	Protein Coding	1
15	LHCGR	Luteinizing Hormone/Choriogonadotropin Receptor	Protein Coding	1
16	TSHR	Thyroid Stimulating Hormone Receptor	Protein Coding	1
17	HGF	Hepatocyte Growth Factor	Protein Coding	1
18	ADAP1	ArfGAP With Dual PH Domains 1	Protein Coding	1
19	EGF	Epidermal Growth Factor	Protein Coding	1
20	ARRB2	Arrestin Beta 2	Protein Coding	1
21	PXN	Paxillin	Protein Coding	1
22	GIT1	GIT ArfGAP 1	Protein Coding	1
23	ITGA2B	Integrin Subunit Alpha 2b	Protein Coding	1
24	NCK1	NCK Adaptor Protein 1	Protein Coding	1
25	MET	MET Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	1
26	ARF6	ARF GTPase 6	Protein Coding	1
27	GNAQ	G Protein Subunit Alpha Q	Protein Coding	1
28	ITGB3	Integrin Subunit Beta 3	Protein Coding	1
29	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
30	ADRB2	Adrenoceptor Beta 2	Protein Coding	1
31	EGFR	Epidermal Growth Factor Receptor	Protein Coding	1
32	AGTR1	Angiotensin II Receptor Type 1	Protein Coding	1

Disorders associated with Arf6 signaling events SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Bleeding disorder, platelet-type, 16	Enrichment	ITGA2B, ITGB3	4.79
2	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGA2B, ITGB3	4.09
3	Glanzmann thrombasthenia 1	Enrichment	ITGA2B, ITGB3	3.95
4	Thrombocytopenia	Enrichment	ITGA2B, ITGB3, SRC	3.72
5	Autosomal dominant macrothrombocytopenia	Enrichment	ITGA2B, ITGB3	3.62
6	Ovarian cancer	Enrichment	EGFR, MET, TSHR	2.77
7	Hypomagnesemia 4, renal	Enrichment	EGF	2.63
8	Deafness, autosomal recessive 39	Enrichment	HGF	2.63
9	Sturge-weber syndrome	Enrichment	GNAQ	2.63
10	Intellectual developmental disorder with short stature and behavioral abnormalities	Enrichment	IQSEC1	2.63
11	Fetomaternal alloimmune thrombocytopenia 2	Enrichment	ITGA2B	2.63
12	Osteofibrous dysplasia	Enrichment	MET	2.63
13	Deafness, autosomal recessive 97	Enrichment	MET	2.63
14	Autism 9	Enrichment	MET	2.63
15	Thrombocytopenia 6	Enrichment	SRC	2.63
16	Arthrogryposis, distal, type 11	Enrichment	MET	2.63
17	Egf-related primary hypomagnesemia with intellectual disability	Enrichment	EGF	2.63
18	Lung cancer	Enrichment	EGFR, MET	2.59
19	Precocious puberty, male-limited	Enrichment	LHCGR	2.33
20	Leydig cell hypoplasia, type i	Enrichment	LHCGR	2.33
21	Hyperthyroidism, familial gestational	Enrichment	TSHR	2.33
22	Immunodeficiency, common variable, 10	Enrichment	PSD	2.33
23	Childhood hepatocellular carcinoma	Enrichment	MET	2.33
24	Papillary renal cell carcinoma	Enrichment	MET	2.33
25	Pseudosarcomatous fibromatosis	Enrichment	USP6	2.33
26	Leydig cell hypoplasia type ii	Enrichment	LHCGR	2.33
27	Phakomatosis cesioflammea	Enrichment	GNAQ	2.33
28	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3	2.15
29	Hyperthyroidism, nonautoimmune	Enrichment	TSHR	2.15
30	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	2.15
31	Hypothyroidism, congenital, nongoitrous, 1	Enrichment	TSHR	2.15
32	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	2.15
33	Neonatal inflammatory skin and bowel disease	Enrichment	EGFR	2.15
34	Familial hyperthyroidism due to mutations in tsh receptor	Enrichment	TSHR	2.15
35	Anastomosing haemangioma	Enrichment	GNAQ	2.15
36	Renal cell carcinoma	Enrichment	MET	2.15
37	Smith-lemli-opitz syndrome	Enrichment	TSHR	2.03
38	Cataract 6, multiple types	Enrichment	EPHA2	1.93
39	Capillary malformations, congenital	Enrichment	GNAQ	1.93
40	Glanzmann thrombasthenia 2	Enrichment	ITGB3	1.93
41	Pseudohermaphroditism	Enrichment	LHCGR	1.93
42	Aniridia	Enrichment	EPHA2	1.93
43	Klippel-trenaunay-weber syndrome	Enrichment	GNAQ	1.85
44	Melanoma, uveal	Enrichment	GNAQ	1.85
45	Cowden syndrome 1	Enrichment	EGFR	1.85
46	Renal tubular dysgenesis	Enrichment	AGTR1	1.85
47	Lung squamous cell carcinoma	Enrichment	EGFR	1.85
48	Hypothyroidism, congenital, nongoitrous, 2	Enrichment	TSHR	1.79
49	Myelofibrosis	Enrichment	SRC	1.79
50	Squamous cell carcinoma, head and neck	Enrichment	EGFR	1.79
51	Renal cell carcinoma, papillary, 1	Enrichment	MET	1.79
52	Common variable immunodeficiency	Enrichment	PSD	1.79
53	Colorectal cancer	Enrichment	MET, SRC	1.75
54	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	HGF, MET	1.73
55	Arthrogryposis, distal, type 1a	Enrichment	MET	1.73
56	Early-onset posterior polar cataract	Enrichment	EPHA2	1.73
57	Adult hepatocellular carcinoma	Enrichment	EGF	1.68
58	Lung non-small cell carcinoma	Enrichment	EGFR	1.59
59	Congenital hypothyroidism	Enrichment	TSHR	1.55
60	Lip and oral cavity carcinoma	Enrichment	EGFR	1.55
61	Osteoporosis	Enrichment	SRC	1.49
62	Lung cancer susceptibility 3	Enrichment	EGFR	1.49
63	Cataract	Enrichment	EPHA2	1.49
64	Renal cell carcinoma, nonpapillary	Enrichment	MET	1.46
65	Gliosarcoma	Enrichment	EGFR	1.43
66	Inherited cancer-predisposing syndrome	Enrichment	EGFR, MET	1.41
67	Hypertension, essential	Enrichment	AGTR1	1.40
68	Cataract 44	Enrichment	EPHA2	1.40
69	Giant cell glioblastoma	Enrichment	EGFR	1.40
70	Early-onset nuclear cataract	Enrichment	EPHA2	1.38
71	Arteriovenous malformations of the brain	Enrichment	EGFR	1.36
72	Hepatocellular carcinoma	Enrichment	MET	1.30
73	Myocardial infarction	Enrichment	ITGB3	1.30
74	Bladder cancer	Enrichment	EGFR	1.18
75	Epilepsy	Enrichment	TSHR	1.04
76	Sensorineural hearing loss	Enrichment	HGF	0.97
77	Autosomal recessive non-syndromic intellectual disability	Enrichment	IQSEC1	0.89

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Arf6 signaling events

Pathway Network for Arf6 signaling events

Member Pathways for Arf6 signaling events

Pathways in the Arf6 signaling events SuperPath

Associated Genes for Arf6 signaling events

Associated Disorders for Arf6 signaling events

Disorders associated with Arf6 signaling events SuperPath

STRING Interaction Network for Arf6 signaling events

Sources for Arf6 signaling events