Arf6 trafficking events

No Pathway Network information available for Arf6 trafficking events

Pathways in the Arf6 trafficking events SuperPath

#	Name	Source	Genes
1	Arf6 trafficking events	PubChem	ACAP1 ADRB2 AGTR1 ARF6 ASAP2 AVPR2 BIN1 CDH1 CLTC CPE CTNNA1 CTNNB1 CTNND1 DNM2 EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6 EXOC7 EXOC8 INS ITGA1 ITGA10 ITGA11 ITGA2 ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAV ITGB1 KLC1 MAPK8IP3 NME1 PIP5K1C PLD1 RALA SCAMP2 SLC2A4 SPAG9 TSHR VAMP3 (see all 47) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACAP1	ArfGAP With Coiled-Coil, Ankyrin Repeat And PH Domains 1	Protein Coding	1
2	SCAMP2	Secretory Carrier Membrane Protein 2	Protein Coding	1
3	ASAP2	ArfGAP With SH3 Domain, Ankyrin Repeat And PH Domain 2	Protein Coding	1
4	MAPK8IP3	Mitogen-Activated Protein Kinase 8 Interacting Protein 3	Protein Coding	1
5	PLD1	Phospholipase D1	Protein Coding	1
6	KLC1	Kinesin Light Chain 1	Protein Coding	1
7	CPE	Carboxypeptidase E	Protein Coding	1
8	TSHR	Thyroid Stimulating Hormone Receptor	Protein Coding	1
9	NME1	NME/NM23 Nucleoside Diphosphate Kinase 1	Protein Coding	1
10	ITGA7	Integrin Subunit Alpha 7	Protein Coding	1
11	ITGA3	Integrin Subunit Alpha 3	Protein Coding	1
12	ITGA11	Integrin Subunit Alpha 11	Protein Coding	1
13	ITGA8	Integrin Subunit Alpha 8	Protein Coding	1
14	ITGA4	Integrin Subunit Alpha 4	Protein Coding	1
15	ITGA6	Integrin Subunit Alpha 6	Protein Coding	1
16	CTNND1	Catenin Delta 1	Protein Coding	1
17	CTNNB1	Catenin Beta 1	Protein Coding	1
18	CTNNA1	Catenin Alpha 1	Protein Coding	1
19	CDH1	Cadherin 1	Protein Coding	1
20	SPAG9	Sperm Associated Antigen 9	Protein Coding	1
21	ITGA9	Integrin Subunit Alpha 9	Protein Coding	1
22	ITGA2	Integrin Subunit Alpha 2	Protein Coding	1
23	ITGA5	Integrin Subunit Alpha 5	Protein Coding	1
24	ITGAV	Integrin Subunit Alpha V	Protein Coding	1
25	ITGA10	Integrin Subunit Alpha 10	Protein Coding	1
26	ITGB1	Integrin Subunit Beta 1	Protein Coding	1
27	ITGA1	Integrin Subunit Alpha 1	Protein Coding	1
28	EXOC2	Exocyst Complex Component 2	Protein Coding	1
29	EXOC4	Exocyst Complex Component 4	Protein Coding	1
30	EXOC5	Exocyst Complex Component 5	Protein Coding	1
31	EXOC7	Exocyst Complex Component 7	Protein Coding	1
32	EXOC1	Exocyst Complex Component 1	Protein Coding	1
33	EXOC6	Exocyst Complex Component 6	Protein Coding	1
34	EXOC8	Exocyst Complex Component 8	Protein Coding	1
35	EXOC3	Exocyst Complex Component 3	Protein Coding	1
36	RALA	RAS Like Proto-Oncogene A	Protein Coding	1
37	BIN1	Bridging Integrator 1	Protein Coding	1
38	ARF6	ARF GTPase 6	Protein Coding	1
39	PIP5K1C	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Gamma	Protein Coding	1
40	DNM2	Dynamin 2	Protein Coding	1
41	VAMP3	Vesicle Associated Membrane Protein 3	Protein Coding	1
42	CLTC	Clathrin Heavy Chain	Protein Coding	1
43	AVPR2	Arginine Vasopressin Receptor 2	Protein Coding	1
44	ADRB2	Adrenoceptor Beta 2	Protein Coding	1
45	SLC2A4	Solute Carrier Family 2 Member 4	Protein Coding	1
46	INS	Insulin	Protein Coding	1
47	AGTR1	Angiotensin II Receptor Type 1	Protein Coding	1

Disorders associated with Arf6 trafficking events SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Blepharocheilodontic syndrome 1	Enrichment	CDH1, CTNND1	4.93
2	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CDH1, CTNNA1	4.15
3	Myopathy, centronuclear, 1	Enrichment	BIN1, DNM2	3.76
4	Cleft lip with or without cleft palate	Enrichment	CDH1, CTNND1	3.76
5	Colorectal cancer	Enrichment	CDH1, CTNNA1, CTNNB1	2.47
6	Nephrogenic syndrome of inappropriate antidiuresis	Enrichment	AVPR2	2.46
7	Diabetes insipidus, nephrogenic, 1, x-linked	Enrichment	AVPR2	2.46
8	Macular dystrophy, patterned, 2	Enrichment	CTNNA1	2.46
9	Cardiac valvular dysplasia 1	Enrichment	PLD1	2.46
10	Charcot-marie-tooth disease, dominant intermediate b	Enrichment	DNM2	2.46
11	Hiatt-neu-cooper neurodevelopmental syndrome	Enrichment	RALA	2.46
12	Bdv syndrome	Enrichment	CPE	2.46
13	X-linked nephrogenic diabetes insipidus	Enrichment	AVPR2	2.46
14	Lethal congenital contracture syndrome 5	Enrichment	DNM2	2.46
15	Neurodevelopmental disorder with seizures and brain atrophy	Enrichment	EXOC7	2.46
16	Neurodevelopmental disorder with microcephaly, seizures, and brain atrophy	Enrichment	EXOC8	2.46
17	Adenoid ameloblastoma	Enrichment	CTNNB1	2.46
18	Autosomal dominant charcot-marie-tooth disease type 2m	Enrichment	DNM2	2.46
19	Breast lobular carcinoma	Enrichment	CDH1	2.46
20	Fetomaternal alloimmune thrombocytopenia 3	Enrichment	ITGA2	2.46
21	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	2.46
22	Cpe-related prader-willi-like syndrome	Enrichment	CPE	2.46
23	Microcystic stromal tumor	Enrichment	CTNNB1	2.46
24	Ovarian cancer	Enrichment	CDH1, CTNNB1, TSHR	2.29
25	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	2.16
26	Lethal congenital contracture syndrome 3	Enrichment	PIP5K1C	2.16
27	Hyperthyroidism, familial gestational	Enrichment	TSHR	2.16
28	Melanoma, cutaneous malignant 6	Enrichment	KLC1	2.16
29	Maturity-onset diabetes of the young, type 10	Enrichment	INS	2.16
30	Hyperproinsulinemia	Enrichment	INS	2.16
31	Blepharocheilodontic syndrome 2	Enrichment	CTNND1	2.16
32	Neurodevelopmental disorder with or without variable brain abnormalities	Enrichment	MAPK8IP3	2.16
33	Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome	Enrichment	ITGA3	2.16
34	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	2.16
35	Diabetes mellitus, permanent neonatal, 4	Enrichment	INS	2.16
36	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	2.16
37	Neurodevelopmental disorder with dysmorphic facies and cerebellar hypoplasia	Enrichment	EXOC2	2.16
38	Teratoma	Enrichment	CTNNB1	2.16
39	Desmoid disease, hereditary	Enrichment	CTNNB1	1.98
40	Type 1 diabetes mellitus 2	Enrichment	INS	1.98
41	Myopathy, centronuclear, x-linked	Enrichment	DNM2	1.98
42	Hyperthyroidism, nonautoimmune	Enrichment	TSHR	1.98
43	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.98
44	Muscular dystrophy, congenital, due to integrin alpha-7 deficiency	Enrichment	ITGA7	1.98
45	Anus, imperforate	Enrichment	CTNNB1	1.98
46	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.98
47	Epidermolysis bullosa, junctional 6, with pyloric atresia	Enrichment	ITGA6	1.98
48	Hypothyroidism, congenital, nongoitrous, 1	Enrichment	TSHR	1.98
49	Intellectual developmental disorder, autosomal dominant 56	Enrichment	CLTC	1.98
50	Desmoid tumor	Enrichment	CTNNB1	1.98
51	Nephrogenic diabetes insipidus	Enrichment	AVPR2	1.98
52	Butterfly-shaped pigment dystrophy	Enrichment	CTNNA1	1.98
53	Familial hyperthyroidism due to mutations in tsh receptor	Enrichment	TSHR	1.98
54	Myopathy, centronuclear, 2	Enrichment	BIN1	1.86
55	Polyposis syndrome, hereditary mixed, 1	Enrichment	CTNNA1	1.86
56	Smith-lemli-opitz syndrome	Enrichment	TSHR	1.86
57	Pilomatrixoma	Enrichment	CTNNB1	1.86
58	Retinitis pigmentosa 26	Enrichment	ITGA4	1.86
59	Alazami syndrome	Enrichment	CTNNB1	1.86
60	Neonatal diabetes mellitus	Enrichment	INS	1.86
61	Neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 1	Enrichment	CLTC	1.86
62	Craniopharyngioma	Enrichment	CTNNB1	1.86
63	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.76
64	Epidermolysis bullosa	Enrichment	ITGA6	1.76
65	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.69
66	Type 1 diabetes mellitus	Enrichment	INS	1.69
67	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGA6	1.69
68	Renal tubular dysgenesis	Enrichment	AGTR1	1.69
69	Inflammatory myofibroblastic tumor	Enrichment	CLTC	1.69
70	Adrenocortical carcinoma	Enrichment	CTNNB1	1.69
71	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGA2	1.69
72	Hypothyroidism, congenital, nongoitrous, 2	Enrichment	TSHR	1.62
73	Noonan syndrome 3	Enrichment	CLTC	1.62
74	Renal cell carcinoma with mit translocations	Enrichment	CLTC	1.62
75	Gallbladder cancer	Enrichment	CTNNB1	1.62
76	Renal hypodysplasia/aplasia 1	Enrichment	ITGA8	1.56
77	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.56
78	Permanent neonatal diabetes mellitus	Enrichment	INS	1.56
79	Breast cancer	Enrichment	CDH1, KLC1	1.56
80	Adult hepatocellular carcinoma	Enrichment	CTNNB1	1.51
81	Junctional epidermolysis bullosa	Enrichment	ITGA6	1.51
82	Renal agenesis, bilateral	Enrichment	ITGA8	1.51
83	Diabetes mellitus	Enrichment	INS	1.43
84	Congenital hypothyroidism	Enrichment	TSHR	1.39
85	Neural tube defects	Enrichment	ITGB1	1.36
86	Medulloblastoma	Enrichment	CTNNB1	1.32
87	Cleft lip/palate	Enrichment	CDH1	1.32
88	Isolated macular dystrophy	Enrichment	ITGA4	1.32
89	Congenital myopathy 4a, autosomal dominant	Enrichment	ITGA7	1.29
90	Hypertension, essential	Enrichment	AGTR1	1.24
91	Polycystic liver disease	Enrichment	CTNNB1	1.24
92	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	1.24
93	Maturity-onset diabetes of the young	Enrichment	INS	1.17
94	Craniosynostosis	Enrichment	CTNNA1	1.17
95	Complex neurodevelopmental disorder	Enrichment	MAPK8IP3, RALA	1.16
96	Endometrial cancer	Enrichment	CDH1	1.15
97	Centronuclear myopathy	Enrichment	DNM2	1.15
98	Hepatoblastoma	Enrichment	CTNNB1	1.15
99	Hepatocellular carcinoma	Enrichment	CTNNB1	1.13
100	Inherited cancer-predisposing syndrome	Enrichment	CDH1, CTNNA1	1.12
101	Bladder cancer	Enrichment	CTNNB1	1.02
102	Prostate cancer	Enrichment	CDH1	1.02
103	Meckel syndrome, type 1	Enrichment	EXOC4	1.02
104	Severe covid-19	Enrichment	ITGAV	1.02
105	Epilepsy	Enrichment	TSHR	0.89
106	Myopathy	Enrichment	DNM2	0.89
107	Charcot-marie-tooth disease	Enrichment	DNM2	0.88
108	Type 2 diabetes mellitus	Enrichment	SLC2A4	0.87
109	Gastric cancer	Enrichment	CDH1	0.86
110	Nephrotic syndrome	Enrichment	ITGA3	0.86
111	Hereditary breast carcinoma	Enrichment	CDH1	0.85
112	Autosomal dominant non-syndromic intellectual disability	Enrichment	CLTC	0.80
113	Hereditary breast ovarian cancer syndrome	Enrichment	CTNNA1	0.76
114	Undetermined early-onset epileptic encephalopathy	Enrichment	CLTC	0.75
115	Cone-rod dystrophy 2	Enrichment	ITGA4	0.68
116	Hereditary retinal dystrophy	Enrichment	CTNNA1, ITGA4	0.58
117	Fundus dystrophy	Enrichment	CTNNA1, ITGA4	0.58
118	Congenital nervous system abnormality	Enrichment	CTNNB1	0.51
119	Nervous system disease	Enrichment	CTNNB1	0.51
120	Microcephaly	Enrichment	CTNNB1	0.46

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Arf6 trafficking events

Pathway Network for Arf6 trafficking events

Member Pathways for Arf6 trafficking events

Pathways in the Arf6 trafficking events SuperPath

Associated Genes for Arf6 trafficking events

Associated Disorders for Arf6 trafficking events

Disorders associated with Arf6 trafficking events SuperPath

STRING Interaction Network for Arf6 trafficking events

Sources for Arf6 trafficking events