Arsenic metabolism and reactive oxygen species generation

No Pathway Network information available for Arsenic metabolism and reactive oxygen species generation

Pathways in the Arsenic metabolism and reactive oxygen species generation SuperPath

#	Name	Source	Genes
1	Arsenic metabolism and reactive oxygen species generation	WikiPathways	AS3MT ATP1A1 CAT COA3 GSTO1 SDHA SOD1 UQCRFS1 VDAC1 (see all 9) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	GSTO1	Glutathione S-Transferase Omega 1	Protein Coding	1
2	CAT	Catalase	Protein Coding	1
3	VDAC1	Voltage Dependent Anion Channel 1	Protein Coding	1
4	UQCRFS1	Ubiquinol-Cytochrome C Reductase, Rieske Iron-Sulfur Polypeptide 1	Protein Coding	1
5	SOD1	Superoxide Dismutase 1	Protein Coding	1
6	SDHA	Succinate Dehydrogenase Complex Flavoprotein Subunit A	Protein Coding	1
7	AS3MT	Arsenite Methyltransferase	Protein Coding	1
8	ATP1A1	ATPase Na+/K+ Transporting Subunit Alpha 1	Protein Coding	1
9	COA3	Cytochrome C Oxidase Assembly Factor 3	Protein Coding	1

Disorders associated with Arsenic metabolism and reactive oxygen species generation SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Pheochromocytoma/paraganglioma syndrome 5	Enrichment	SDHA	3.18
2	Mitochondrial complex iv deficiency, nuclear type 14	Enrichment	COA3	3.18
3	Acatalasemia	Enrichment	CAT	3.18
4	Cardiomyopathy, dilated, 1gg	Enrichment	SDHA	3.18
5	Mitochondrial complex iii deficiency, nuclear type 10	Enrichment	UQCRFS1	3.18
6	Neurodegeneration with ataxia and late-onset optic atrophy	Enrichment	SDHA	3.18
7	Polymyoclonus, infantile	Enrichment	SDHA	2.88
8	Charcot-marie-tooth disease, axonal, type 2dd	Enrichment	ATP1A1	2.88
9	Hypomagnesemia, seizures, and impaired intellectual development 2	Enrichment	ATP1A1	2.88
10	Spastic tetraplegia and axial hypotonia, progressive	Enrichment	SOD1	2.88
11	Carney triad	Enrichment	SDHA	2.70
12	Paraganglioma	Enrichment	SDHA	2.70
13	Brain cancer	Enrichment	SDHA	2.70
14	Pheochromocytoma/paraganglioma syndrome 1	Enrichment	SDHA	2.58
15	Mitochondrial complex ii deficiency, nuclear type 1	Enrichment	SDHA	2.58
16	Propionic acidemia	Enrichment	UQCRFS1	2.58
17	Pilocytic astrocytoma	Enrichment	SDHA	2.58
18	Mitochondrial complex ii deficiency	Enrichment	SDHA	2.58
19	Amyotrophic lateral sclerosis 10 with or without frontotemporal dementia	Enrichment	SOD1	2.48
20	Gastrointestinal stromal tumor	Enrichment	SDHA	2.33
21	Motor neuron disease	Enrichment	SOD1	2.33
22	Amyotrophic lateral sclerosis 1	Enrichment	SOD1	2.18
23	Isolated complex iii deficiency	Enrichment	UQCRFS1	2.14
24	Lactic acidosis	Enrichment	UQCRFS1	2.10
25	Pheochromocytoma	Enrichment	SDHA	2.03
26	Cox deficiency, benign infantile mitochondrial myopathy	Enrichment	COA3	2.03
27	Rhabdomyosarcoma	Enrichment	SDHA	1.98
28	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	SDHA	1.86
29	Mitochondrial complex iv deficiency, nuclear type 1	Enrichment	COA3	1.84
30	Hereditary breast carcinoma	Enrichment	SDHA	1.54
31	Familial isolated dilated cardiomyopathy	Enrichment	SDHA	1.46
32	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	SOD1	1.42
33	Leigh syndrome, nuclear	Enrichment	SDHA	1.35
34	Breast cancer	Enrichment	SDHA	1.31
35	Leigh disease	Enrichment	SDHA	1.31
36	Inherited cancer-predisposing syndrome	Enrichment	SDHA	1.07

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Arsenic metabolism and reactive oxygen species generation

Pathway Network for Arsenic metabolism and reactive oxygen species generation

Member Pathways for Arsenic metabolism and reactive oxygen species generation

Pathways in the Arsenic metabolism and reactive oxygen species generation SuperPath

Associated Genes for Arsenic metabolism and reactive oxygen species generation

Associated Disorders for Arsenic metabolism and reactive oxygen species generation

Disorders associated with Arsenic metabolism and reactive oxygen species generation SuperPath

STRING Interaction Network for Arsenic metabolism and reactive oxygen species generation

Sources for Arsenic metabolism and reactive oxygen species generation