Aspartate and asparagine metabolism

No Pathway Network information available for Aspartate and asparagine metabolism

#	Name	Source	Genes
1	Aspartate and asparagine metabolism	Reactome	ASNS ASPA ASPG FOLH1 GADL1 GOT1 GOT2 NAALAD2 NAT8L SLC25A12 SLC25A13 (see all 11) (see less)
2	asparagine biosynthesis	PubChem	ASNS

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ASNS	Asparagine Synthetase (Glutamine-Hydrolyzing)	Protein Coding	2
2	NAALAD2	N-Acetylated Alpha-Linked Acidic Dipeptidase 2	Protein Coding	1
3	SLC25A13	Solute Carrier Family 25 Member 13	Protein Coding	1
4	FOLH1	Folate Hydrolase 1	Protein Coding	1
5	GOT1	Glutamic-Oxaloacetic Transaminase 1	Protein Coding	1
6	GOT2	Glutamic-Oxaloacetic Transaminase 2	Protein Coding	1
7	GADL1	Glutamate Decarboxylase Like 1	Protein Coding	1
8	NAT8L	N-Acetyltransferase 8 Like	Protein Coding	1
9	ASPG	Asparaginase	Protein Coding	1
10	ASPA	Aspartoacylase	Protein Coding	1
11	SLC25A12	Solute Carrier Family 25 Member 12	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Asparagine synthetase deficiency	Enrichment	ASNS	3.66
2	Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome	Enrichment	ASNS	3.66
3	Spinocerebellar ataxia, autosomal recessive 29	Enrichment	ASNS	3.66
4	Developmental and epileptic encephalopathy 39 with leukodystrophy	Enrichment	SLC25A12	3.09
5	Aspartate aminotransferase, serum level of, quantitative trait locus 1	Enrichment	GOT1	3.09
6	N-acetylaspartate deficiency	Enrichment	NAT8L	3.09
7	Developmental and epileptic encephalopathy 39	Enrichment	SLC25A12	3.09
8	Citrullinemia type ii	Enrichment	SLC25A13	3.09
9	Citrullinemia, classic	Enrichment	SLC25A13	2.79
10	Canavan disease	Enrichment	ASPA	2.79
11	Citrin deficiency, neonatal or infantile onset	Enrichment	SLC25A13	2.79
12	Bainbridge-ropers syndrome	Enrichment	GADL1	2.79
13	Developmental and epileptic encephalopathy 82	Enrichment	GOT2	2.79
14	Citrullinemia	Enrichment	SLC25A13	2.79
15	Citrin deficiency, adolescent or adult onset	Enrichment	SLC25A13	2.61
16	Developmental and epileptic encephalopathy 1	Enrichment	SLC25A12	1.70
17	Developmental and epileptic encephalopathy	Enrichment	GOT2	1.54
18	West syndrome	Enrichment	SLC25A12	1.45
19	Autism	Enrichment	ASPA	1.25

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Aspartate and asparagine metabolism