Autosomal recessive osteopetrosis pathways

No Pathway Network information available for Autosomal recessive osteopetrosis pathways

Pathways in the Autosomal recessive osteopetrosis pathways SuperPath

#	Name	Source	Genes
1	Autosomal recessive osteopetrosis pathways	WikiPathways	CLCN7 IKBKB NFKB1 OSTM1 PLEKHM1 RAB7A SNX10 TCIRG1 TNFRSF11A TNFSF11 TRAF6 (see all 11) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PLEKHM1	Pleckstrin Homology And RUN Domain Containing M1	Protein Coding	1
2	TNFRSF11A	TNF Receptor Superfamily Member 11a	Protein Coding	1
3	TNFSF11	TNF Superfamily Member 11	Protein Coding	1
4	RAB7A	RAB7A, Member RAS Oncogene Family	Protein Coding	1
5	TRAF6	TNF Receptor Associated Factor 6	Protein Coding	1
6	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
7	IKBKB	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta	Protein Coding	1
8	SNX10	Sorting Nexin 10	Protein Coding	1
9	OSTM1	Osteoclastogenesis Associated Transmembrane Protein 1	Protein Coding	1
10	CLCN7	Chloride Voltage-Gated Channel 7	Protein Coding	1
11	TCIRG1	T Cell Immune Regulator 1, ATPase H+ Transporting V0 Subunit A3	Protein Coding	1

Disorders associated with Autosomal recessive osteopetrosis pathways SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Osteopetrosis	Enrichment	CLCN7, OSTM1, SNX10, TCIRG1	10.81
2	Autosomal recessive osteopetrosis	Enrichment	CLCN7, SNX10, TCIRG1, TNFSF11	10.77
3	Osteopetrosis, autosomal recessive 6	Enrichment	CLCN7, PLEKHM1, TCIRG1	9.39
4	Dysosteosclerosis	Enrichment	TCIRG1, TNFRSF11A	5.75
5	Osteopetrosis, autosomal dominant 2	Enrichment	CLCN7	3.09
6	Osteopetrosis, autosomal recessive 7	Enrichment	TNFRSF11A	3.09
7	Immunodeficiency 15b	Enrichment	IKBKB	3.09
8	Immunodeficiency 15a	Enrichment	IKBKB	3.09
9	Hypopigmentation, organomegaly, and delayed myelination and development	Enrichment	CLCN7	3.09
10	Charcot-marie-tooth disease, axonal, type 2b	Enrichment	RAB7A	3.09
11	Charcot-marie-tooth disease type 2b	Enrichment	RAB7A	3.09
12	Osteopetrosis, autosomal dominant 3	Enrichment	PLEKHM1	3.09
13	Osteopetrosis, autosomal recessive 8	Enrichment	SNX10	3.09
14	Familial expansile osteolysis	Enrichment	TNFRSF11A	2.79
15	Paget disease of bone 5, juvenile-onset	Enrichment	TNFRSF11A	2.79
16	Osteopetrosis, autosomal recessive 4	Enrichment	CLCN7	2.79
17	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.79
18	Osteopetrosis, autosomal recessive 2	Enrichment	TNFSF11	2.79
19	Osteopetrosis, autosomal recessive 5	Enrichment	OSTM1	2.79
20	Osteopetrosis, autosomal recessive 1	Enrichment	TCIRG1	2.79
21	Osteosclerosis	Enrichment	CLCN7	2.79
22	Common variable immunodeficiency 12	Enrichment	NFKB1	2.79
23	Infantile osteopetrosis with neuroaxonal dysplasia	Enrichment	OSTM1	2.79
24	Choreoacanthocytosis	Enrichment	TCIRG1	2.61
25	Neutropenia, severe congenital, 1, autosomal dominant	Enrichment	TCIRG1	2.61
26	Adult-onset myasthenia gravis	Enrichment	TNFRSF11A	2.61
27	Paget disease of bone 2, early-onset	Enrichment	TNFRSF11A	2.49
28	Paget's disease of bone 2	Enrichment	TNFRSF11A	2.49
29	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	TRAF6	2.39
30	Autosomal dominant severe congenital neutropenia	Enrichment	TCIRG1	2.39
31	Common variable immunodeficiency	Enrichment	NFKB1	2.25
32	Severe congenital neutropenia	Enrichment	TCIRG1	2.19
33	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	2.09
34	Severe combined immunodeficiency	Enrichment	IKBKB	1.58

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Autosomal recessive osteopetrosis pathways

Pathway Network for Autosomal recessive osteopetrosis pathways

Member Pathways for Autosomal recessive osteopetrosis pathways

Pathways in the Autosomal recessive osteopetrosis pathways SuperPath

Associated Genes for Autosomal recessive osteopetrosis pathways

Associated Disorders for Autosomal recessive osteopetrosis pathways

Disorders associated with Autosomal recessive osteopetrosis pathways SuperPath

STRING Interaction Network for Autosomal recessive osteopetrosis pathways

Sources for Autosomal recessive osteopetrosis pathways