BAFF in B-Cell Signaling

Pathway network for the BAFF in B-Cell Signaling SuperPath

Sources:

QIAGEN
GeneGo (Thomson Reuters)

Pathways in the BAFF in B-Cell Signaling SuperPath

#	Name	Source	Genes
1	BAFF in B-Cell Signaling	QIAGEN	CHUK ELK1 FOS IKBKB IKBKE IKBKG JUN MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAP3K14 MAP3K7 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK8 MAPK9 NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NFKB1 NFKBIA NFKBIB NFKBIE TAB1 TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13B TRAF2 TRAF3 TRAF5 TRAF6 (see all 38) (see less)
2	RANK Signaling in Osteoclasts	QIAGEN	ARAF BIRC2 BIRC3 BRAF CBL CHUK ELK1 FOS GSN IKBKB IKBKE IKBKG JUN MAP2K1 MAP2K2 MAP2K7 MAP3K14 MAP3K2 MAP3K3 MAP3K4 MAP3K5 MAP3K7 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK8 MAPK9 MITF NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NFKB1 NFKBIA NFKBIB NFKBIE PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PTK2B RAF1 SRC TAB2 TNFRSF11A TNFSF11 TRAF2 TRAF5 TRAF6 XIAP (see all 56) (see less)
3	Apoptosis and survival APRIL and BAFF signaling	GeneGo (Thomson Reuters)	BCL2 BCL2A1 BCL2L1 CAMLG CCL4 CHUK CR2 FCER2 IKBKB IKBKG IL10 MAP2K4 MAP3K1 MAP3K14 MAPK10 MAPK8 MAPK9 NFATC1 NFATC2 NFKB1 NFKB2 NFKBIA NFKBIB NFKBIE PPIB PPP3CA PPP3CB PPP3CC PTGS2 RELA RELB TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13 TNFSF13B TRAF2 TRAF3 TRAF5 TRAF6 (see all 40) (see less)
4	APRIL Pathway	QIAGEN	CHUK ELK1 FOS IKBKB IKBKE IKBKG JUN MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAP3K14 MAP3K7 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK8 MAPK9 NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NFKB1 NFKBIA NFKBIB NFKBIE TAB1 TNFRSF13B TNFRSF17 TNFSF13 TRAF2 TRAF3 TRAF5 TRAF6 (see all 37) (see less)
5	RANK Pathway	QIAGEN	CBL CHUK FOS IKBKB IKBKE IKBKG JUN NFKB1 NFKBIA NFKBIB NFKBIE PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 SRC TNFRSF11A TNFSF11 TRAF1 TRAF2 TRAF3 TRAF5 TRAF6 (see all 24) (see less)

Gene overlap in member pathways for BAFF in B-Cell Signaling SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	5
2	IKBKB	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta	Protein Coding	5
3	IKBKG	Inhibitor Of Nuclear Factor Kappa B Kinase Regulatory Subunit Gamma	Protein Coding	5
4	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	5
5	NFKBIA	NFKB Inhibitor Alpha	Protein Coding	5
6	NFKBIB	NFKB Inhibitor Beta	Protein Coding	5
7	NFKBIE	NFKB Inhibitor Epsilon	Protein Coding	5
8	TRAF2	TNF Receptor Associated Factor 2	Protein Coding	5
9	TRAF5	TNF Receptor Associated Factor 5	Protein Coding	5
10	TRAF6	TNF Receptor Associated Factor 6	Protein Coding	5
11	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	4
12	IKBKE	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Epsilon	Protein Coding	4
13	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	4
14	MAP3K14	Mitogen-Activated Protein Kinase Kinase Kinase 14	Protein Coding	4
15	MAPK10	Mitogen-Activated Protein Kinase 10	Protein Coding	4
16	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	4
17	MAPK9	Mitogen-Activated Protein Kinase 9	Protein Coding	4
18	NFATC1	Nuclear Factor Of Activated T Cells 1	Protein Coding	4
19	NFATC2	Nuclear Factor Of Activated T Cells 2	Protein Coding	4
20	TRAF3	TNF Receptor Associated Factor 3	Protein Coding	4
21	ELK1	ETS Transcription Factor ELK1	Protein Coding	3
22	MAP2K4	Mitogen-Activated Protein Kinase Kinase 4	Protein Coding	3
23	MAP2K7	Mitogen-Activated Protein Kinase Kinase 7	Protein Coding	3
24	MAP3K7	Mitogen-Activated Protein Kinase Kinase Kinase 7	Protein Coding	3
25	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	3
26	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	3
27	MAPK13	Mitogen-Activated Protein Kinase 13	Protein Coding	3
28	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	3
29	NFAT5	Nuclear Factor Of Activated T Cells 5	Protein Coding	3
30	NFATC3	Nuclear Factor Of Activated T Cells 3	Protein Coding	3
31	NFATC4	Nuclear Factor Of Activated T Cells 4	Protein Coding	3
32	TNFRSF13B	TNF Receptor Superfamily Member 13B	Protein Coding	3
33	TNFRSF17	TNF Receptor Superfamily Member 17	Protein Coding	3
34	MAP2K3	Mitogen-Activated Protein Kinase Kinase 3	Protein Coding	2
35	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	2
36	TAB1	TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 1	Protein Coding	2
37	TNFRSF13C	TNF Receptor Superfamily Member 13C	Protein Coding	2
38	TNFSF13B	TNF Superfamily Member 13b	Protein Coding	2
39	CBL	Cbl Proto-Oncogene	Protein Coding	2
40	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	2
41	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	2
42	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	2
43	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	2
44	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	2
45	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	2
46	TNFRSF11A	TNF Receptor Superfamily Member 11a	Protein Coding	2
47	TNFSF11	TNF Superfamily Member 11	Protein Coding	2
48	TNFSF13	TNF Superfamily Member 13	Protein Coding	2
49	ARAF	A-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
50	BIRC2	Baculoviral IAP Repeat Containing 2	Protein Coding	1
51	BIRC3	Baculoviral IAP Repeat Containing 3	Protein Coding	1
52	XIAP	X-Linked Inhibitor Of Apoptosis	Protein Coding	1
53	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
54	GSN	Gelsolin	Protein Coding	1
55	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
56	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	1
57	MAP3K2	Mitogen-Activated Protein Kinase Kinase Kinase 2	Protein Coding	1
58	MAP3K3	Mitogen-Activated Protein Kinase Kinase Kinase 3	Protein Coding	1
59	MAP3K4	Mitogen-Activated Protein Kinase Kinase Kinase 4	Protein Coding	1
60	MAP3K5	Mitogen-Activated Protein Kinase Kinase Kinase 5	Protein Coding	1
61	TAB2	TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 2	Protein Coding	1
62	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
63	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
64	MITF	Melanocyte Inducing Transcription Factor	Protein Coding	1
65	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	1
66	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
67	BCL2	BCL2 Apoptosis Regulator	Protein Coding	1
68	BCL2A1	BCL2 Related Protein A1	Protein Coding	1
69	BCL2L1	BCL2 Like 1	Protein Coding	1
70	CAMLG	Calcium Modulating Ligand	Protein Coding	1
71	CR2	Complement C3d Receptor 2	Protein Coding	1
72	FCER2	Fc Epsilon Receptor II	Protein Coding	1
73	IL10	Interleukin 10	Protein Coding	1
74	MAP3K1	Mitogen-Activated Protein Kinase Kinase Kinase 1	Protein Coding	1
75	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
76	PPIB	Peptidylprolyl Isomerase B	Protein Coding	1
77	PPP3CA	Protein Phosphatase 3 Catalytic Subunit Alpha	Protein Coding	1
78	PPP3CB	Protein Phosphatase 3 Catalytic Subunit Beta	Protein Coding	1
79	PPP3CC	Protein Phosphatase 3 Catalytic Subunit Gamma	Protein Coding	1
80	PTGS2	Prostaglandin-Endoperoxide Synthase 2	Protein Coding	1
81	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	1
82	RELB	RELB Proto-Oncogene, NF-KB Subunit	Protein Coding	1
83	CCL4	C-C Motif Chemokine Ligand 4	Protein Coding	1
84	TRAF1	TNF Receptor Associated Factor 1	Protein Coding	1

Disorders associated with BAFF in B-Cell Signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF, CBL, MAP2K1, MAP2K2, RAF1	8.53
2	Noonan syndrome 1	Enrichment	BRAF, CBL, MAP2K1, MAP2K2, RAF1	7.50
3	Rasopathy	Enrichment	BRAF, CBL, MAP2K1, MAP2K2, RAF1	7.21
4	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF, MAP2K1, MAP2K2	6.58
5	Cardiofaciocutaneous syndrome	Enrichment	BRAF, MAP2K1, MAP2K2	6.58
6	Common variable immunodeficiency	Enrichment	NFKB1, NFKB2, TNFRSF13B	6.08
7	Ectodermal dysplasia and immune deficiency	Enrichment	IKBKG, NFKBIA	5.52
8	Immunodeficiency, common variable, 2	Enrichment	CR2, TNFRSF13B	5.07
9	Langerhans cell histiocytosis	Enrichment	BRAF, MAP2K1	4.30
10	Immunodeficiency, common variable, 1	Enrichment	NFKB2, TNFRSF13B	4.30
11	Noonan syndrome with multiple lentigines	Enrichment	BRAF, RAF1	4.00
12	Pilomyxoid astrocytoma	Enrichment	BRAF, RAF1	3.46
13	Melanocytic nevus syndrome, congenital	Enrichment	BRAF, RAF1	3.34
14	Melanoma	Enrichment	BRAF, MITF	3.13
15	Lung non-small cell carcinoma	Enrichment	BRAF, MAP2K1	3.05
16	Myeloma, multiple	Enrichment	BRAF, PIK3R2, TRAF5	2.80
17	Incontinentia pigmenti	Enrichment	IKBKG	2.75
18	Autoinflammatory disease, systemic, x-linked	Enrichment	IKBKG	2.75
19	Osteopetrosis, autosomal recessive 7	Enrichment	TNFRSF11A	2.75
20	Fetal encasement syndrome	Enrichment	CHUK	2.75
21	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	2.75
22	Immunodeficiency 15b	Enrichment	IKBKB	2.75
23	Immunodeficiency 15a	Enrichment	IKBKB	2.75
24	Short syndrome	Enrichment	PIK3R1	2.75
25	Ectodermal dysplasia and immunodeficiency 1	Enrichment	IKBKG	2.75
26	Immunodeficiency 132a	Enrichment	TRAF3	2.75
27	Immunodeficiency 132b	Enrichment	TRAF3	2.75
28	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.75
29	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.75
30	Thrombocytopenia 6	Enrichment	SRC	2.75
31	Bartsocas-papas syndrome 2	Enrichment	CHUK	2.75
32	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	2.75
33	Melanoma, cutaneous malignant 1	Enrichment	BRAF, MITF	2.66
34	Immune deficiency, familial variable	Enrichment	TNFRSF13B	2.56
35	Cardiospondylocarpofacial syndrome	Enrichment	MAP3K7	2.56
36	Frontometaphyseal dysplasia 2	Enrichment	MAP3K7	2.56
37	Immunoglobulin a deficiency 2	Enrichment	TNFRSF13B	2.56
38	Immunodeficiency 112	Enrichment	MAP3K14	2.56
39	Common variable immunodeficiency phenotype due to homozygous taci deficiency	Enrichment	TNFRSF13B	2.56
40	Inflammatory bowel disease-recurrent sinopulmonary infections syndrome	Enrichment	NFAT5	2.56
41	Nik deficiency	Enrichment	MAP3K14	2.56
42	46,xy sex reversal 6	Enrichment	MAP3K1	2.53
43	Congenital disorder of glycosylation, type iiz	Enrichment	CAMLG	2.53
44	Developmental and epileptic encephalopathy 91	Enrichment	PPP3CA	2.53
45	Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development	Enrichment	PPP3CA	2.53
46	Graft-versus-host disease	Enrichment	IL10	2.53
47	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	2.53
48	Immunodeficiency 53	Enrichment	RELB	2.53
49	Familial expansile osteolysis	Enrichment	TNFRSF11A	2.45
50	Paget disease of bone 5, juvenile-onset	Enrichment	TNFRSF11A	2.45
51	Ovarian germ cell cancer	Enrichment	CBL	2.45
52	Immunodeficiency 33	Enrichment	IKBKG	2.45
53	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	2.45
54	Ectodermal dysplasia and immunodeficiency 2	Enrichment	NFKBIA	2.45
55	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.45
56	Osteopetrosis, autosomal recessive 2	Enrichment	TNFSF11	2.45
57	Glucosephosphate dehydrogenase deficiency	Enrichment	IKBKG	2.45
58	Malignant germ cell tumor of ovary	Enrichment	CBL	2.45
59	Common variable immunodeficiency 12	Enrichment	NFKB1	2.45
60	Pallister-killian syndrome	Enrichment	ARAF	2.38
61	Lymphoproliferative syndrome, x-linked, 2	Enrichment	XIAP	2.38
62	Noonan syndrome 5	Enrichment	RAF1	2.38
63	Melorheostosis, isolated	Enrichment	MAP2K1	2.38
64	Noonan syndrome 7	Enrichment	BRAF	2.38
65	Leopard syndrome 3	Enrichment	BRAF	2.38
66	Amyloidosis, finnish type	Enrichment	GSN	2.38
67	Heterochromia iridis	Enrichment	MITF	2.38
68	Tietz albinism-deafness syndrome	Enrichment	MITF	2.38
69	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.38
70	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.38
71	Noonan syndrome 13	Enrichment	MAPK1	2.38
72	Coloboma, osteopetrosis, microphthalmia, macrocephaly, albinism, and deafness	Enrichment	MITF	2.38
73	Lymphangioma	Enrichment	BRAF	2.38
74	Phace association	Enrichment	BRAF	2.38
75	Melorheostosis	Enrichment	MAP2K1	2.38
76	Leopard syndrome 2	Enrichment	RAF1	2.38
77	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	2.38
78	Trigonitis	Enrichment	RAF1	2.38
79	Cerebral cavernous malformations 5	Enrichment	MAP3K3	2.38
80	Syringocystadenoma papilliferum	Enrichment	BRAF	2.38
81	Ganglioglioma	Enrichment	BRAF	2.38
82	Nongerminomatous germ cell tumor	Enrichment	BRAF	2.38
83	Phace syndrome	Enrichment	BRAF	2.38
84	Classic hairy cell leukemia	Enrichment	BRAF	2.38
85	Verrucous hemangioma	Enrichment	MAP3K3	2.38
86	Polyvalvular heart disease syndrome	Enrichment	TAB2	2.38
87	Dilated cardiomyopathy	Enrichment	BRAF, RAF1, TAB2	2.36
88	Dysosteosclerosis	Enrichment	TNFRSF11A	2.28
89	Nasopharyngeal carcinoma	Enrichment	NFKBIA	2.28
90	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3R1	2.28
91	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	2.28
92	Immunodeficiency 14	Enrichment	PIK3R1	2.28
93	Adult-onset myasthenia gravis	Enrichment	TNFRSF11A	2.28
94	Immunodeficiency with hyper-igm, type 2	Enrichment	TNFRSF13B	2.26
95	Joint contractures, osteochondromas, and b-cell lymphoma	Enrichment	NFATC2	2.26
96	Colorectal cancer	Enrichment	BRAF, PIK3R1, SRC	2.26
97	Immunodeficiency, common variable, 4	Enrichment	TNFRSF13C	2.25
98	Systemic lupus erythematosus	Enrichment	CR2, IL10	2.23
99	Osteogenesis imperfecta, type ix	Enrichment	PPIB	2.23
100	Immunodeficiency, common variable, 10	Enrichment	NFKB2	2.23
101	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	2.23
102	Intravascular large b-cell lymphoma	Enrichment	BCL2	2.23
103	Immunodeficiency, common variable, 7	Enrichment	CR2	2.23
104	Rela fusion-positive ependymoma	Enrichment	RELA	2.23
105	Paget disease of bone 2, early-onset	Enrichment	TNFRSF11A	2.15
106	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3R2	2.15
107	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	PIK3R2	2.15
108	Congenital generalized lipodystrophy	Enrichment	FOS	2.15
109	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CBL	2.15
110	Autosomal recessive osteopetrosis	Enrichment	TNFSF11	2.15
111	Paget's disease of bone 2	Enrichment	TNFRSF11A	2.15
112	Frontometaphyseal dysplasia	Enrichment	MAP3K7	2.09
113	Pulmonic stenosis	Enrichment	BRAF	2.08
114	Melanoma, cutaneous malignant 8	Enrichment	MITF	2.08
115	Papillary renal cell carcinoma	Enrichment	MITF	2.08
116	Congenital heart defects, multiple types, 2	Enrichment	TAB2	2.08
117	Cardiac anomalies-short stature-joint hypermobility-facial dysmorphism syndrome	Enrichment	TAB2	2.08
118	Tafro syndrome	Enrichment	MAP2K2	2.08
119	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	TRAF6	2.05
120	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	IKBKG	2.05
121	Myeloproliferative neoplasm	Enrichment	CBL	2.05
122	Histiocytoid hemangioma	Enrichment	FOS	2.05
123	Herpes simplex virus encephalitis	Enrichment	TRAF3	2.05
124	Aggressive systemic mastocytosis	Enrichment	CBL	2.05
125	Systemic lupus erythematosus 9	Enrichment	CR2	2.05
126	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL2	2.05
127	Myelofibrosis	Enrichment	SRC	1.91
128	Overgrowth syndrome	Enrichment	PIK3R1	1.91
129	Pelvic organ prolapse	Enrichment	TAB2	1.91
130	Ataxia-telangiectasia	Enrichment	BRAF	1.91
131	Waardenburg syndrome, type 2a	Enrichment	MITF	1.91
132	Tethered spinal cord syndrome	Enrichment	BRAF	1.91
133	Follicular lymphoma	Enrichment	BCL2	1.83
134	Coronary heart disease 5	Enrichment	IKBKG	1.80
135	Thyroid cancer, nonmedullary, 1	Enrichment	BRAF	1.78
136	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.78
137	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.78
138	Lymphoproliferative syndrome 2	Enrichment	XIAP	1.78
139	Craniopharyngioma	Enrichment	BRAF	1.78
140	Newborn respiratory distress syndrome	Enrichment	BRAF	1.78
141	Clear cell papillary renal cell carcinoma	Enrichment	MITF	1.78
142	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.76
143	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3R1	1.76
144	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10	1.76
145	Osteogenesis imperfecta, type ii	Enrichment	PPIB	1.69
146	Lymphoma, mucosa-associated lymphoid type	Enrichment	BIRC3	1.69
147	Juvenile myelomonocytic leukemia	Enrichment	CBL	1.68
148	Lennox-gastaut syndrome	Enrichment	MAPK10	1.67
149	Osteoporosis	Enrichment	SRC	1.61
150	Waardenburg syndrome, type 4a	Enrichment	MITF	1.61
151	Wilms tumor 5	Enrichment	BRAF	1.61
152	Waardenburg syndrome	Enrichment	MITF	1.61
153	Rheumatoid arthritis	Enrichment	IL10	1.58
154	Rhabdomyosarcoma	Enrichment	CBL	1.55
155	Gliosarcoma	Enrichment	NFKBIA	1.55
156	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF	1.54
157	Waardenburg syndrome, type 1	Enrichment	MITF	1.54
158	Waardenburg syndrome, type 2e	Enrichment	MITF	1.54
159	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1	1.54
160	Noonan syndrome 3	Enrichment	RAF1	1.54
161	Gallbladder cancer	Enrichment	BRAF	1.54
162	Follicular thyroid carcinoma	Enrichment	BRAF	1.54
163	Giant cell glioblastoma	Enrichment	NFKBIA	1.53
164	46,xy complete gonadal dysgenesis	Enrichment	MAP3K1	1.50
165	Lymphoma, non-hodgkin, familial	Enrichment	BRAF	1.49
166	Cardiomyopathy, familial hypertrophic, 4	Enrichment	BRAF	1.44
167	Arteriovenous malformation	Enrichment	MAP2K1	1.44
168	Primary hyperaldosteronism	Enrichment	BRAF	1.44
169	Ventricular septal defect	Enrichment	BRAF	1.44
170	Osteogenesis imperfecta, type iv	Enrichment	PPIB	1.42
171	Multisystem inflammatory syndrome in children	Enrichment	TRAF3	1.42
172	Malaria	Enrichment	IKBKG	1.40
173	46,xy partial gonadal dysgenesis	Enrichment	MAP3K1	1.39
174	Myopathy, x-linked, with excessive autophagy	Enrichment	MAP2K1	1.39
175	Osteogenesis imperfecta, type iii	Enrichment	PPIB	1.36
176	Migraine with or without aura 1	Enrichment	TAB2	1.35
177	Specific learning disability	Enrichment	MAPK1	1.35
178	Lip and oral cavity carcinoma	Enrichment	BRAF	1.31
179	Human immunodeficiency virus type 1	Enrichment	IL10	1.29
180	Aortic valve disease 1	Enrichment	TAB2	1.28
181	Behcet syndrome	Enrichment	IL10	1.26
182	Cardiomyopathy, dilated, 1a	Enrichment	NFATC2	1.25
183	Lung cancer susceptibility 3	Enrichment	BRAF	1.25
184	Severe combined immunodeficiency	Enrichment	IKBKB	1.25
185	Wilms tumor 1	Enrichment	BRAF	1.22
186	Brittle bone disorder	Enrichment	PPIB	1.18
187	Dandy-walker syndrome	Enrichment	BRAF	1.17
188	Heart, malformation of	Enrichment	MAPK1	1.14
189	Patent foramen ovale	Enrichment	TAB2	1.14
190	Arteriovenous malformations of the brain	Enrichment	BRAF	1.12
191	Diffuse large b-cell lymphoma	Enrichment	BRAF	1.12
192	Thrombocytopenia	Enrichment	SRC	1.09
193	Ear malformation	Enrichment	MITF	1.02
194	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	1.02
195	Autoinflammatory disease	Enrichment	XIAP	1.02
196	Differentiated thyroid carcinoma	Enrichment	BRAF	0.95
197	Lung cancer	Enrichment	BRAF	0.91
198	Breast cancer	Enrichment	JUN	0.90
199	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.89
200	Left ventricular noncompaction	Enrichment	RAF1	0.87
201	Autosomal dominant non-syndromic intellectual disability	Enrichment	PPP3CA	0.86
202	Non-syndromic genetic deafness	Enrichment	MITF	0.86
203	Undetermined early-onset epileptic encephalopathy	Enrichment	PPP3CA	0.82
204	Nonsyndromic hearing loss	Enrichment	MITF	0.80
205	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	MITF	0.71
206	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.71
207	Hereditary breast ovarian cancer syndrome	Enrichment	MITF	0.69
208	Ovarian cancer	Enrichment	MAP3K1	0.59
209	Rare genetic deafness	Enrichment	MITF	0.55
210	Autism spectrum disorder	Enrichment	MAP2K1	0.44
211	Microcephaly	Enrichment	MAPK1	0.40
212	Inherited cancer-predisposing syndrome	Enrichment	MITF	0.37

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

BAFF in B-Cell Signaling

Pathway Network for BAFF in B-Cell Signaling

Pathway network for the BAFF in B-Cell Signaling SuperPath

Member Pathways for BAFF in B-Cell Signaling

Pathways in the BAFF in B-Cell Signaling SuperPath

Gene overlap in member pathways for BAFF in B-Cell Signaling SuperPath

Associated Genes for BAFF in B-Cell Signaling

Associated Disorders for BAFF in B-Cell Signaling

Disorders associated with BAFF in B-Cell Signaling SuperPath

STRING Interaction Network for BAFF in B-Cell Signaling

Sources for BAFF in B-Cell Signaling