BARD1 signaling events

No Pathway Network information available for BARD1 signaling events

Pathways in the BARD1 signaling events SuperPath

#	Name	Source	Genes
1	BARD1 signaling events	PubChem	ATM ATR BACH1 BARD1 BRCA1 CCNE1 CDK2 CSTF1 EWSR1 FANCA FANCC FANCD2 FANCE FANCF FANCG FANCL MRE11 NBN PCNA PRKDC RAD50 RAD51 RBBP8 TOPBP1 TP53 UBE2D3 UBE2L3 XRCC5 XRCC6 (see all 29) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	EWSR1	EWS RNA Binding Protein 1	Protein Coding	1
2	BACH1	BACH Transcriptional Regulator 1	Protein Coding	1
3	CSTF1	Cleavage Stimulation Factor Subunit 1	Protein Coding	1
4	CCNE1	Cyclin E1	Protein Coding	1
5	UBE2D3	Ubiquitin Conjugating Enzyme E2 D3	Protein Coding	1
6	FANCG	FA Complementation Group G	Protein Coding	1
7	FANCC	FA Complementation Group C	Protein Coding	1
8	FANCE	FA Complementation Group E	Protein Coding	1
9	FANCL	FA Complementation Group L	Protein Coding	1
10	FANCA	FA Complementation Group A	Protein Coding	1
11	FANCD2	FA Complementation Group D2	Protein Coding	1
12	FANCF	FA Complementation Group F	Protein Coding	1
13	XRCC5	X-Ray Repair Cross Complementing 5	Protein Coding	1
14	XRCC6	X-Ray Repair Cross Complementing 6	Protein Coding	1
15	TOPBP1	DNA Topoisomerase II Binding Protein 1	Protein Coding	1
16	BARD1	BRCA1 Associated RING Domain 1	Protein Coding	1
17	PCNA	Proliferating Cell Nuclear Antigen	Protein Coding	1
18	UBE2L3	Ubiquitin Conjugating Enzyme E2 L3	Protein Coding	1
19	RBBP8	RB Binding Protein 8, Endonuclease	Protein Coding	1
20	RAD50	RAD50 Double Strand Break Repair Protein	Protein Coding	1
21	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	1
22	MRE11	MRE11 Double Strand Break Repair Nuclease	Protein Coding	1
23	RAD51	RAD51 Recombinase	Protein Coding	1
24	NBN	Nibrin	Protein Coding	1
25	CDK2	Cyclin Dependent Kinase 2	Protein Coding	1
26	ATR	ATR Checkpoint Kinase	Protein Coding	1
27	PRKDC	Protein Kinase, DNA-Activated, Catalytic Subunit	Protein Coding	1
28	ATM	ATM Serine/Threonine Kinase	Protein Coding	1
29	TP53	Tumor Protein P53	Protein Coding	1

Disorders associated with BARD1 signaling events SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Breast cancer	Enrichment	ATM, BARD1, BRCA1, FANCC, MRE11, NBN, RAD50, RAD51, TP53	16.00
2	Ovarian cancer	Enrichment	ATM, BARD1, BRCA1, FANCA, FANCC, FANCD2, FANCE, FANCG, MRE11, NBN, RAD50, TP53	16.00
3	Pancreatic cancer	Enrichment	ATM, BRCA1, FANCE, FANCG, NBN, RBBP8, TP53	16.00
4	Fanconi anemia, complementation group a	Enrichment	BRCA1, FANCA, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCL, RAD51	11.89
5	Hereditary breast carcinoma	Enrichment	ATM, BARD1, BRCA1, NBN, RAD50, RAD51, TP53	11.84
6	Hereditary breast ovarian cancer syndrome	Enrichment	ATM, BARD1, BRCA1, MRE11, NBN, RAD50, RAD51, TP53	10.89
7	Inherited cancer-predisposing syndrome	Enrichment	ATM, BARD1, BRCA1, FANCA, FANCC, MRE11, NBN, RAD50, TP53	10.75
8	Gastric cancer	Enrichment	ATM, BARD1, BRCA1, NBN, TP53	7.55
9	Prostate cancer	Enrichment	ATM, BRCA1, NBN, TP53	6.41
10	Colorectal cancer	Enrichment	ATM, BRCA1, FANCC, FANCE, TP53	5.99
11	Breast-ovarian cancer, familial 1	Enrichment	ATM, BRCA1, NBN	5.61
12	Endometrial cancer	Enrichment	ATM, BARD1, BRCA1	4.94
13	Hepatoblastoma	Enrichment	BARD1, FANCA, TP53	4.94
14	Hepatocellular carcinoma	Enrichment	NBN, RAD50, TP53	4.88
15	Adenocarcinoma	Enrichment	ATM, TP53	4.88
16	Nijmegen breakage syndrome-like disorder	Enrichment	MRE11, RAD50	4.58
17	Bladder cancer	Enrichment	ATM, BRCA1, TP53	4.51
18	Colonic benign neoplasm	Enrichment	ATM, MRE11	3.80
19	Leukemia, chronic lymphocytic	Enrichment	ATM, TP53	3.71
20	Myeloma, multiple	Enrichment	ATM, BARD1, TP53	3.65
21	Uterine corpus cancer	Enrichment	ATM, BRCA1	3.62
22	Seckel syndrome	Enrichment	ATR, RBBP8	3.40
23	Pituitary stalk interruption syndrome	Enrichment	FANCA, FANCG	3.40
24	Rhabdomyosarcoma	Enrichment	BRCA1, TP53	3.28
25	Gliosarcoma	Enrichment	ATM, TP53	3.28
26	Giant cell glioblastoma	Enrichment	ATM, TP53	3.23
27	Diffuse large b-cell lymphoma	Enrichment	NBN, TP53	3.13
28	Palmoplantar keratoderma, punctate type ii	Enrichment	BRCA1	2.67
29	Seckel syndrome 2	Enrichment	RBBP8	2.67
30	Seckel syndrome 1	Enrichment	ATR	2.67
31	Mirror movements 2	Enrichment	RAD51	2.67
32	Fanconi anemia, complementation group g	Enrichment	FANCG	2.67
33	Fanconi anemia, complementation group r	Enrichment	RAD51	2.67
34	Bone marrow failure syndrome 5	Enrichment	TP53	2.67
35	Papilloma of choroid plexus	Enrichment	TP53	2.67
36	Basal cell carcinoma 7	Enrichment	TP53	2.67
37	Anaplastic thyroid carcinoma	Enrichment	TP53	2.67
38	Infant-type hemispheric glioma	Enrichment	BRCA1	2.67
39	Jawad syndrome	Enrichment	RBBP8	2.67
40	Ataxia-telangiectasia-like disorder 1	Enrichment	MRE11	2.67
41	Cutaneous telangiectasia and cancer syndrome, familial	Enrichment	ATR	2.67
42	Immunodeficiency 26 with or without neurologic abnormalities	Enrichment	PRKDC	2.67
43	Ataxia-telangiectasia-like disorder 2	Enrichment	PCNA	2.67
44	Endometrial serous adenocarcinoma	Enrichment	ATM	2.67
45	Ductal carcinoma in situ	Enrichment	TP53	2.67
46	Fanconi anemia, complementation group l	Enrichment	FANCL	2.67
47	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	2.67
48	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	2.67
49	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	2.67
50	B-cell non-hodgkin lymphoma	Enrichment	ATM	2.67
51	Choroid plexus cancer	Enrichment	TP53	2.67
52	Pleomorphic xanthoastrocytoma	Enrichment	TP53	2.67
53	Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome	Enrichment	ATR	2.67
54	Primary peritoneal carcinoma	Enrichment	BRCA1	2.67
55	Leukemia, acute myeloid	Enrichment	FANCD2, TP53	2.49
56	Adrenocortical carcinoma, hereditary	Enrichment	TP53	2.37
57	Cervical cancer	Enrichment	TP53	2.37
58	Vacterl association, x-linked, with or without hydrocephalus	Enrichment	FANCL	2.37
59	Histiocytoma, angiomatoid fibrous	Enrichment	EWSR1	2.37
60	Lymphoma, hodgkin, classic	Enrichment	TP53	2.37
61	Fanconi anemia, complementation group s	Enrichment	BRCA1	2.37
62	Cardiac valvular dysplasia, x-linked	Enrichment	ATM	2.37
63	Pancreatic cancer 4	Enrichment	BRCA1	2.37
64	Fanconi anemia, complementation group e	Enrichment	FANCE	2.37
65	Congenital fibrosarcoma	Enrichment	TP53	2.37
66	High grade glioma	Enrichment	ATM	2.37
67	Li-fraumeni syndrome 1	Enrichment	TP53	2.37
68	Sarcoma	Enrichment	TP53	2.37
69	Cervix carcinoma	Enrichment	TP53	2.37
70	Hodgkin's lymphoma	Enrichment	TP53	2.37
71	T-cell prolymphocytic leukemia	Enrichment	ATM	2.37
72	Inflammatory breast carcinoma	Enrichment	BRCA1	2.37
73	Peritoneum cancer	Enrichment	BRCA1	2.37
74	Bilateral breast cancer	Enrichment	BRCA1	2.37
75	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	2.37
76	Desmoplastic small round cell tumor	Enrichment	EWSR1	2.37
77	Ataxia-telangiectasia	Enrichment	ATM	2.19
78	Nijmegen breakage syndrome	Enrichment	NBN	2.19
79	Polycythemia vera	Enrichment	ATM	2.19
80	Osteogenic sarcoma	Enrichment	TP53	2.19
81	Nasopharyngeal carcinoma	Enrichment	TP53	2.19
82	Fanconi anemia, complementation group f	Enrichment	FANCF	2.19
83	Koolen-de vries syndrome	Enrichment	ATM	2.19
84	Atypical teratoid rhabdoid tumor	Enrichment	TP53	2.19
85	Anaplastic astrocytoma	Enrichment	TP53	2.19
86	Squamous cell carcinoma	Enrichment	TP53	2.19
87	Bone osteosarcoma	Enrichment	TP53	2.19
88	Melanoma of soft tissue	Enrichment	EWSR1	2.19
89	Primary ovarian insufficiency	Enrichment	FANCA, NBN	2.15
90	Mirror movements 1	Enrichment	RAD51	2.07
91	Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia	Enrichment	MRE11	2.07
92	Small cell cancer of the lung	Enrichment	TP53	2.07
93	Erythrocytosis, familial, 2	Enrichment	FANCD2	2.07
94	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	2.07
95	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA1	2.07
96	Cholangiocarcinoma	Enrichment	BRCA1	2.07
97	Mantle cell lymphoma	Enrichment	ATM	2.07
98	Lung sarcomatoid carcinoma	Enrichment	TP53	2.07
99	Embryonal rhabdomyosarcoma	Enrichment	TP53	2.07
100	Vacterl association	Enrichment	FANCL	2.07
101	Oculomotor apraxia	Enrichment	ATM	2.07
102	Fanconi anemia, complementation group d2	Enrichment	FANCD2	1.97
103	Vater/vacterl association	Enrichment	FANCL	1.97
104	Von hippel-lindau syndrome	Enrichment	FANCD2	1.97
105	Rhabdomyosarcoma 2	Enrichment	TP53	1.97
106	Chondrosarcoma, extraskeletal myxoid	Enrichment	EWSR1	1.97
107	Breast-ovarian cancer, familial 2	Enrichment	BRCA1	1.97
108	Lymphoma	Enrichment	TP53	1.97
109	Glioblastoma	Enrichment	ATM	1.97
110	Acute megakaryocytic leukemia	Enrichment	TP53	1.97
111	Li-fraumeni syndrome	Enrichment	TP53	1.89
112	Adrenocortical carcinoma	Enrichment	TP53	1.89
113	Clear cell renal cell carcinoma	Enrichment	ATM	1.89
114	Breast adenocarcinoma	Enrichment	TP53	1.89
115	Esophageal cancer	Enrichment	TP53	1.83
116	Squamous cell carcinoma, head and neck	Enrichment	TP53	1.83
117	Renal cell carcinoma, papillary, 1	Enrichment	ATM	1.83
118	Essential thrombocythemia	Enrichment	TP53	1.83
119	Gallbladder cancer	Enrichment	TP53	1.83
120	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	TP53	1.83
121	Glioma susceptibility 1	Enrichment	TP53	1.77
122	Fanconi anemia, complementation group c	Enrichment	FANCC	1.77
123	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.77
124	Ewing sarcoma	Enrichment	EWSR1	1.77
125	Neurofibromatosis, type i	Enrichment	EWSR1	1.72
126	Adult hepatocellular carcinoma	Enrichment	TP53	1.72
127	Primary hyperaldosteronism	Enrichment	TP53	1.72
128	Lynch syndrome 1	Enrichment	ATM	1.67
129	Aplastic anemia	Enrichment	NBN	1.67
130	Familial colorectal cancer	Enrichment	TP53	1.67
131	Immune deficiency disease	Enrichment	ATM	1.63
132	Leukemia, acute lymphoblastic	Enrichment	NBN	1.63
133	Myelodysplastic syndrome	Enrichment	TP53	1.63
134	Familial colorectal cancer type x	Enrichment	ATM	1.63
135	Lip and oral cavity carcinoma	Enrichment	TP53	1.60
136	Premature menopause	Enrichment	NBN	1.56
137	Lung cancer susceptibility 3	Enrichment	TP53	1.53
138	Periventricular nodular heterotopia	Enrichment	BRCA1	1.53
139	Renal cell carcinoma, nonpapillary	Enrichment	ATM	1.50
140	Lissencephaly	Enrichment	NBN	1.36
141	Diamond-blackfan anemia 1	Enrichment	TP53	1.32
142	Lung cancer	Enrichment	BRCA1	1.18
143	Diamond-blackfan anemia	Enrichment	TP53	1.13
144	Systemic lupus erythematosus	Enrichment	UBE2L3	1.10
145	Microcephaly	Enrichment	NBN	0.63

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

BARD1 signaling events

Pathway Network for BARD1 signaling events

Member Pathways for BARD1 signaling events

Pathways in the BARD1 signaling events SuperPath

Associated Genes for BARD1 signaling events

Associated Disorders for BARD1 signaling events

Disorders associated with BARD1 signaling events SuperPath

STRING Interaction Network for BARD1 signaling events

Sources for BARD1 signaling events