BCR signaling pathway

No Pathway Network information available for BCR signaling pathway

Pathways in the BCR signaling pathway SuperPath

#	Name	Source	Genes
1	BCR signaling pathway	PubChem	AKT1 BCL10 BCL2A1 BCL6 BCR BLNK BTK CAMK2G CARD11 CD19 CD22 CD72 CD79A CD79B CHUK CSK CSNK2A1 DAPP1 DOK1 ELK1 ETS1 FCGR2B FOS GRB2 HRAS IBTK IKBKB IKBKG JUN LYN MALT1 MAP2K1 MAP3K1 MAP3K7 MAP4K1 MAPK14 MAPK3 MAPK8 NFATC1 NFKB1 NFKBIA NFKBIB PAG1 PDPK1 PIK3CA PIK3R1 PLCG2 POU2F2 PPP3CA PPP3CB PPP3CC PRRT2 PTEN PTPN6 PTPRC RAC1 RAF1 RASA1 RELA SH3BP5 SHC1 SOS1 SYK TRAF6 VAV2 (see all 65) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	NFKBIB	NFKB Inhibitor Beta	Protein Coding	1
2	IBTK	Inhibitor Of Bruton Tyrosine Kinase	Protein Coding	1
3	SH3BP5	SH3 Domain Binding Protein 5	Protein Coding	1
4	POU2F2	POU Class 2 Homeobox 2	Protein Coding	1
5	PRRT2	Proline Rich Transmembrane Protein 2	Protein Coding	1
6	FCGR2B	Fc Gamma Receptor IIb	Protein Coding	1
7	MAP4K1	Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1	Protein Coding	1
8	CSNK2A1	Casein Kinase 2 Alpha 1	Protein Coding	1
9	PPP3CA	Protein Phosphatase 3 Catalytic Subunit Alpha	Protein Coding	1
10	BCL2A1	BCL2 Related Protein A1	Protein Coding	1
11	DAPP1	Dual Adaptor Of Phosphotyrosine And 3-Phosphoinositides 1	Protein Coding	1
12	BLNK	B Cell Linker	Protein Coding	1
13	CD79A	CD79a Molecule	Protein Coding	1
14	CD79B	CD79b Molecule	Protein Coding	1
15	CD22	CD22 Molecule	Protein Coding	1
16	CARD11	Caspase Recruitment Domain Family Member 11	Protein Coding	1
17	MALT1	MALT1 Paracaspase	Protein Coding	1
18	BCR	BCR Activator Of RhoGEF And GTPase	Protein Coding	1
19	BCL10	BCL10 Immune Signaling Adaptor	Protein Coding	1
20	BCL6	BCL6 Transcription Repressor	Protein Coding	1
21	ETS1	ETS Proto-Oncogene 1, Transcription Factor	Protein Coding	1
22	NFKBIA	NFKB Inhibitor Alpha	Protein Coding	1
23	IKBKB	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta	Protein Coding	1
24	IKBKG	Inhibitor Of Nuclear Factor Kappa B Kinase Regulatory Subunit Gamma	Protein Coding	1
25	DOK1	Docking Protein 1	Protein Coding	1
26	CD19	CD19 Molecule	Protein Coding	1
27	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	1
28	TRAF6	TNF Receptor Associated Factor 6	Protein Coding	1
29	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
30	MAP3K7	Mitogen-Activated Protein Kinase Kinase Kinase 7	Protein Coding	1
31	NFATC1	Nuclear Factor Of Activated T Cells 1	Protein Coding	1
32	BTK	Bruton Tyrosine Kinase	Protein Coding	1
33	CAMK2G	Calcium/Calmodulin Dependent Protein Kinase II Gamma	Protein Coding	1
34	ELK1	ETS Transcription Factor ELK1	Protein Coding	1
35	PAG1	Phosphoprotein Membrane Anchor With Glycosphingolipid Microdomains 1	Protein Coding	1
36	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	1
37	PPP3CC	Protein Phosphatase 3 Catalytic Subunit Gamma	Protein Coding	1
38	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
39	PTEN	Phosphatase And Tensin Homolog	Protein Coding	1
40	CSK	C-Terminal Src Kinase	Protein Coding	1
41	SYK	Spleen Associated Tyrosine Kinase	Protein Coding	1
42	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	1
43	LYN	LYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
44	PTPN6	Protein Tyrosine Phosphatase Non-Receptor Type 6	Protein Coding	1
45	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
46	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
47	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	1
48	RASA1	RAS P21 Protein Activator 1	Protein Coding	1
49	VAV2	Vav Guanine Nucleotide Exchange Factor 2	Protein Coding	1
50	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
51	PPP3CB	Protein Phosphatase 3 Catalytic Subunit Beta	Protein Coding	1
52	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
53	CD72	CD72 Molecule	Protein Coding	1
54	PTPRC	Protein Tyrosine Phosphatase Receptor Type C	Protein Coding	1
55	RAC1	Rac Family Small GTPase 1	Protein Coding	1
56	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	1
57	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	1
58	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	1
59	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
60	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
61	SHC1	SHC Adaptor Protein 1	Protein Coding	1
62	PLCG2	Phospholipase C Gamma 2	Protein Coding	1
63	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
64	MAP3K1	Mitogen-Activated Protein Kinase Kinase Kinase 1	Protein Coding	1
65	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1

Disorders associated with BCR signaling pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Arteriovenous malformation	Enrichment	HRAS, MAP2K1, PIK3CA, RASA1	7.23
2	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, MAP2K1, PIK3CA, RASA1	7.01
3	Autosomal non-syndromic agammaglobulinemia	Enrichment	BLNK, CD79A, CD79B, PIK3R1	7.01
4	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, MAP2K1, RAF1, SOS1	6.20
5	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1, PIK3CA, RASA1	5.44
6	Noonan syndrome 3	Enrichment	HRAS, RAF1, SOS1	5.44
7	Noonan syndrome 1	Enrichment	HRAS, MAP2K1, RAF1, SOS1	5.40
8	Rasopathy	Enrichment	HRAS, MAP2K1, RAF1, SOS1	5.18
9	Cowden syndrome	Enrichment	AKT1, PIK3CA, PTEN	5.06
10	Lung non-small cell carcinoma	Enrichment	HRAS, MAP2K1, PIK3CA	4.77
11	Meningioma	Enrichment	AKT1, PIK3CA, PTEN	4.65
12	Ectodermal dysplasia and immune deficiency	Enrichment	IKBKG, NFKBIA	4.65
13	Breast cancer	Enrichment	AKT1, JUN, PIK3CA, PTEN, SHC1	4.54
14	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	4.17
15	Diffuse large b-cell lymphoma	Enrichment	BTK, CD79B, PTEN	4.02
16	Lymphoma, mucosa-associated lymphoid type	Enrichment	BCL10, MALT1	3.65
17	Capillary malformations, congenital	Enrichment	PIK3CA, RASA1	3.65
18	Follicular lymphoma	Enrichment	BCL10, BCL6	3.65
19	Hemimegalencephaly	Enrichment	PIK3CA, PTEN	3.65
20	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA, RASA1	3.48
21	Cowden syndrome 1	Enrichment	PIK3CA, PTEN	3.48
22	Breast adenocarcinoma	Enrichment	AKT1, PIK3CA	3.48
23	Bladder cancer	Enrichment	HRAS, PIK3CA, PTEN	3.45
24	Nevus, epidermal	Enrichment	HRAS, PIK3CA	3.33
25	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS, PTEN	3.33
26	Follicular thyroid carcinoma	Enrichment	HRAS, PTEN	3.33
27	Severe combined immunodeficiency	Enrichment	IKBKB, MALT1, PTPRC	3.29
28	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, RAF1	3.21
29	Colorectal cancer	Enrichment	AKT1, BCL10, PIK3CA, PIK3R1	3.10
30	Hereditary breast carcinoma	Enrichment	AKT1, PIK3CA, PTEN	2.92
31	Ovarian cancer	Enrichment	AKT1, MAP3K1, PIK3CA, PTEN	2.86
32	Lip and oral cavity carcinoma	Enrichment	HRAS, PIK3CA	2.84
33	46,xy partial gonadal dysgenesis	Enrichment	MAP3K1, SOS1	2.70
34	Rhabdomyosarcoma	Enrichment	HRAS, PTEN	2.59
35	Endometrial cancer	Enrichment	PIK3CA, PTEN	2.35
36	Macrodactyly	Enrichment	PIK3CA	2.32
37	Proteus syndrome	Enrichment	AKT1	2.32
38	Cardiospondylocarpofacial syndrome	Enrichment	MAP3K7	2.32
39	Cystic angiomatosis of bone, diffuse	Enrichment	RASA1	2.32
40	Vacterl association with hydrocephalus	Enrichment	PTEN	2.32
41	Incontinentia pigmenti	Enrichment	IKBKG	2.32
42	Autoinflammatory disease, systemic, x-linked	Enrichment	IKBKG	2.32
43	Noonan syndrome 5	Enrichment	RAF1	2.32
44	Noonan syndrome 4	Enrichment	SOS1	2.32
45	Melorheostosis, isolated	Enrichment	MAP2K1	2.32
46	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.32
47	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.32
48	Cowden syndrome 5	Enrichment	PIK3CA	2.32
49	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.32
50	Fetal encasement syndrome	Enrichment	CHUK	2.32
51	46,xy sex reversal 6	Enrichment	MAP3K1	2.32
52	Frontometaphyseal dysplasia 2	Enrichment	MAP3K7	2.32
53	Agammaglobulinemia 3, autosomal recessive	Enrichment	CD79A	2.32
54	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.32
55	Immunodeficiency 15b	Enrichment	IKBKB	2.32
56	Immunodeficiency 82 with systemic inflammation	Enrichment	SYK	2.32
57	Immunodeficiency 15a	Enrichment	IKBKB	2.32
58	Developmental and epileptic encephalopathy 91	Enrichment	PPP3CA	2.32
59	Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development	Enrichment	PPP3CA	2.32
60	Short syndrome	Enrichment	PIK3R1	2.32
61	Ectodermal dysplasia and immunodeficiency 1	Enrichment	IKBKG	2.32
62	Isolated growth hormone deficiency type iii	Enrichment	BTK	2.32
63	Persistent polyclonal b-cell lymphocytosis	Enrichment	CARD11	2.32
64	Papillary tumor of the pineal region	Enrichment	PTEN	2.32
65	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.32
66	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.32
67	Melorheostosis	Enrichment	MAP2K1	2.32
68	Leopard syndrome 2	Enrichment	RAF1	2.32
69	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.32
70	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	2.32
71	Cowden syndrome 6	Enrichment	AKT1	2.32
72	Immunodeficiency 12	Enrichment	MALT1	2.32
73	Immunodeficiency, common variable, 3	Enrichment	CD19	2.32
74	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.32
75	Immunodeficiency 105, severe combined	Enrichment	PTPRC	2.32
76	Glioma susceptibility 2	Enrichment	PTEN	2.32
77	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	2.32
78	Okur-chung neurodevelopmental syndrome	Enrichment	CSNK2A1	2.32
79	Bartsocas-papas syndrome 2	Enrichment	CHUK	2.32
80	Autoinflammatory disease, systemic, with vasculitis	Enrichment	LYN	2.32
81	Cd45 deficiency	Enrichment	PTPRC	2.32
82	Trigonitis	Enrichment	RAF1	2.32
83	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.32
84	Sezary's disease	Enrichment	BCL10	2.32
85	Intellectual developmental disorder, autosomal dominant 59	Enrichment	CAMK2G	2.32
86	Hypospadias	Enrichment	PIK3CA	2.32
87	Colitis	Enrichment	SYK	2.32
88	Rare venous malformation	Enrichment	PIK3CA	2.32
89	Vegetative pyoderma gangrenosum	Enrichment	PTPN6	2.32
90	Bullous pyoderma gangrenosum	Enrichment	PTPN6	2.32
91	Gorham's disease	Enrichment	RASA1	2.32
92	Diaphragmatic eventration	Enrichment	PIK3CA	2.32
93	Agammaglobulinemia 3	Enrichment	CD79A	2.32
94	Pustular pyoderma gangrenosum	Enrichment	PTPN6	2.32
95	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.32
96	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	2.32
97	Rare combined vascular malformation	Enrichment	PIK3CA	2.32
98	Cavernous lymphangioma	Enrichment	PIK3CA	2.32
99	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.32
100	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.32
101	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	2.32
102	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.32
103	Classic pyoderma gangrenosum	Enrichment	PTPN6	2.32
104	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.32
105	Mucosa-associated lymphoma	Enrichment	BCL10	2.32
106	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.32
107	Macrodactyly of toe	Enrichment	PIK3CA	2.32
108	Malaria	Enrichment	FCGR2B, IKBKG	2.27
109	Prostate cancer	Enrichment	PIK3CA, PTEN	2.07
110	Fibromatosis, gingival, 1	Enrichment	SOS1	2.02
111	Costello syndrome	Enrichment	HRAS	2.02
112	Immunodeficiency 33	Enrichment	IKBKG	2.02
113	Pulmonic stenosis	Enrichment	SOS1	2.02
114	Isolated growth hormone deficiency, type iii, with agammaglobulinemia	Enrichment	BTK	2.02
115	Agammaglobulinemia 4, autosomal recessive	Enrichment	BLNK	2.02
116	Ectodermal dysplasia and immunodeficiency 2	Enrichment	NFKBIA	2.02
117	Seizures, benign familial infantile, 2	Enrichment	PRRT2	2.02
118	Agammaglobulinemia 6, autosomal recessive	Enrichment	CD79B	2.02
119	Keratosis, seborrheic	Enrichment	PIK3CA	2.02
120	Immunodeficiency 11a	Enrichment	CARD11	2.02
121	Immunodeficiency 37	Enrichment	BCL10	2.02
122	Noonan syndrome 8	Enrichment	PIK3CA	2.02
123	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.02
124	Myopia 28, autosomal recessive	Enrichment	DOK1	2.02
125	Immunodeficiency 11b with atopic dermatitis	Enrichment	CARD11	2.02
126	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	2.02
127	Agammaglobulinemia, x-linked	Enrichment	BTK	2.02
128	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	2.02
129	Intravascular large b-cell lymphoma	Enrichment	BCL6	2.02
130	Rela fusion-positive ependymoma	Enrichment	RELA	2.02
131	Agammaglobulinemia 4	Enrichment	BLNK	2.02
132	Agammaglobulinemia 6	Enrichment	CD79B	2.02
133	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	2.02
134	B-cell expansion with nfkb and t-cell anergy	Enrichment	CARD11	2.02
135	Immunodeficiency 104, severe combined	Enrichment	PTPRC	2.02
136	Glucosephosphate dehydrogenase deficiency	Enrichment	IKBKG	2.02
137	Common variable immunodeficiency phenotype due to cd19/cd81 deficiency	Enrichment	CD19	2.02
138	Vacterl with hydrocephalus	Enrichment	PTEN	2.02
139	Arthritis	Enrichment	SYK	2.02
140	Primary mediastinal large b-cell lymphoma	Enrichment	BCL6	2.02
141	Common variable immunodeficiency 12	Enrichment	NFKB1	2.02
142	Juvenile polyposis of infancy	Enrichment	PTEN	2.02
143	Prrt2-related disorder	Enrichment	PRRT2	2.02
144	Wooly hair nevus	Enrichment	HRAS	2.02
145	Jacobsen syndrome	Enrichment	ETS1	1.84
146	Mesothelioma, malignant	Enrichment	BCL10	1.84
147	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.84
148	Agammaglobulinemia 1, autosomal recessive	Enrichment	BTK	1.84
149	Nuchal bleb, familial	Enrichment	SOS1	1.84
150	Langerhans cell histiocytosis	Enrichment	MAP2K1	1.84
151	Glut1 deficiency syndrome 2	Enrichment	PRRT2	1.84
152	Nasopharyngeal carcinoma	Enrichment	NFKBIA	1.84
153	Neutrophilic dermatosis, acute febrile	Enrichment	PTPN6	1.84
154	Chromosome 8p11 myeloproliferative syndrome	Enrichment	BCR	1.84
155	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3R1	1.84
156	Agammaglobulinemia 1	Enrichment	BTK	1.84
157	Large congenital melanocytic nevus	Enrichment	HRAS	1.84
158	Wieacker-wolff syndrome	Enrichment	RASA1	1.84
159	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL6	1.84
160	Frontometaphyseal dysplasia	Enrichment	MAP3K7	1.84
161	Immunodeficiency 14	Enrichment	PIK3R1	1.84
162	T-cell acute lymphoblastic leukemia	Enrichment	BCL10	1.84
163	Laryngeal squamous cell carcinoma	Enrichment	PTEN	1.84
164	Spermatocytoma	Enrichment	HRAS	1.84
165	Testicular cancer	Enrichment	BCL10	1.84
166	Keratoacanthoma	Enrichment	PIK3CA	1.84
167	Systemic lupus erythematosus	Enrichment	ETS1, FCGR2B	1.83
168	Autism spectrum disorder	Enrichment	CSNK2A1, MAP2K1, PTEN	1.81
169	Gastric cancer	Enrichment	PIK3CA, PTEN	1.74
170	Paroxysmal nonkinesigenic dyskinesia 1	Enrichment	PRRT2	1.72
171	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS	1.72
172	Episodic kinesigenic dyskinesia 1	Enrichment	PRRT2	1.72
173	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K1	1.72
174	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3CA	1.72
175	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	BCR	1.72
176	Congenital generalized lipodystrophy	Enrichment	FOS	1.72
177	Cardiofaciocutaneous syndrome	Enrichment	MAP2K1	1.72
178	Cerebrovascular disease	Enrichment	PIK3CA	1.72
179	Noonan syndrome with multiple lentigines	Enrichment	RAF1	1.72
180	Epidermolytic nevus	Enrichment	HRAS	1.72
181	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.72
182	Familial paroxysmal nonkinesigenic dyskinesia	Enrichment	PRRT2	1.72
183	Familial or sporadic hemiplegic migraine	Enrichment	PRRT2	1.72
184	Glioma	Enrichment	PTEN	1.72
185	Gingival fibromatosis	Enrichment	SOS1	1.72
186	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	TRAF6	1.62
187	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	IKBKG	1.62
188	Convulsions, familial infantile, with paroxysmal choreoathetosis	Enrichment	PRRT2	1.62
189	Macrocephaly/autism syndrome	Enrichment	PTEN	1.62
190	Hemangioma	Enrichment	PTEN	1.62
191	Histiocytoid hemangioma	Enrichment	FOS	1.62
192	Acute megakaryocytic leukemia	Enrichment	PTEN	1.62
193	Self-limited infantile epilepsy	Enrichment	PRRT2	1.62
194	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	RASA1	1.55
195	Hemihyperplasia, isolated	Enrichment	PIK3CA	1.55
196	Testicular germ cell tumor	Enrichment	BCL10	1.55
197	Hemangioma, capillary infantile	Enrichment	RASA1	1.55
198	Basal cell carcinoma 1	Enrichment	RASA1	1.55
199	Lung squamous cell carcinoma	Enrichment	PIK3CA	1.55
200	Squamous cell carcinoma, head and neck	Enrichment	PTEN	1.48
201	Leukemia, chronic myeloid	Enrichment	BCR	1.48
202	Gallbladder cancer	Enrichment	PIK3CA	1.48
203	Hereditary hemorrhagic telangiectasia	Enrichment	RASA1	1.48
204	Pilomyxoid astrocytoma	Enrichment	RAF1	1.48
205	Common variable immunodeficiency	Enrichment	NFKB1	1.48
206	Overgrowth syndrome	Enrichment	PIK3R1	1.48
207	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	BCR	1.48
208	Lymphoma, non-hodgkin, familial	Enrichment	BCL10	1.42
209	Coronary heart disease 5	Enrichment	IKBKG	1.37
210	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	1.37
211	Adult hepatocellular carcinoma	Enrichment	PIK3CA	1.37
212	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.33
213	Melanoma	Enrichment	PTEN	1.33
214	Immune deficiency disease	Enrichment	SYK	1.29
215	Asthma	Enrichment	CARD11	1.29
216	Meningioma, familial	Enrichment	PTEN	1.29
217	Combined immunodeficiency	Enrichment	MALT1	1.29
218	46,xy complete gonadal dysgenesis	Enrichment	MAP3K1	1.29
219	Combined t cell and b cell immunodeficiency	Enrichment	MALT1	1.29
220	Uterine corpus cancer	Enrichment	PTEN	1.29
221	Combined t and b cell immunodeficiency	Enrichment	MALT1	1.29
222	Aortic valve disease 1	Enrichment	SOS1	1.22
223	Generalized epilepsy with febrile seizures plus	Enrichment	PRRT2	1.19
224	Lynch syndrome	Enrichment	PIK3CA	1.16
225	Gliosarcoma	Enrichment	NFKBIA	1.13
226	Giant cell glioblastoma	Enrichment	NFKBIA	1.11
227	Hepatocellular carcinoma	Enrichment	PIK3CA	1.00
228	Precursor t-cell acute lymphoblastic leukemia	Enrichment	BCR	0.98
229	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	0.96
230	Hydrops fetalis, nonimmune	Enrichment	HRAS	0.93
231	Differentiated thyroid carcinoma	Enrichment	HRAS	0.89
232	Non-immune hydrops fetalis	Enrichment	HRAS	0.86
233	Lung cancer	Enrichment	PIK3CA	0.85
234	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.83
235	Left ventricular noncompaction	Enrichment	RAF1	0.81
236	Autosomal dominant non-syndromic intellectual disability	Enrichment	PPP3CA	0.67
237	Hypertelorism	Enrichment	PIK3CA	0.65
238	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.65
239	Hereditary breast ovarian cancer syndrome	Enrichment	PTEN	0.63
240	Undetermined early-onset epileptic encephalopathy	Enrichment	PPP3CA	0.63
241	Autism	Enrichment	CAMK2G	0.53
242	Dilated cardiomyopathy	Enrichment	RAF1	0.50
243	Congenital nervous system abnormality	Enrichment	PTEN	0.40
244	Nervous system disease	Enrichment	PTEN	0.40
245	Complex neurodevelopmental disorder	Enrichment	CSNK2A1	0.35
246	Inherited cancer-predisposing syndrome	Enrichment	PTEN	0.33

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

BCR signaling pathway

Pathway Network for BCR signaling pathway

Member Pathways for BCR signaling pathway

Pathways in the BCR signaling pathway SuperPath

Associated Genes for BCR signaling pathway

Associated Disorders for BCR signaling pathway

Disorders associated with BCR signaling pathway SuperPath

STRING Interaction Network for BCR signaling pathway

Sources for BCR signaling pathway