Beta-Adrenergic Signaling

Pathway network for the Beta-Adrenergic Signaling SuperPath

Sources:

QIAGEN
Tocris

Pathways in the Beta-Adrenergic Signaling SuperPath

#	Name	Source	Genes
1	Beta-Adrenergic Signaling	QIAGEN	ADCY1 ADCY2 ADCY3 ADORA1 ADRB1 ADRB2 ARAF ATP2A1 ATP2A2 ATP2A3 BRAF CACNA1B CACNA1C CACNA1D CACNA1S GNAI1 GNAI2 GNAI3 GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 HRAS KRAS MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAP2K7 MRAS NRAS PLA2G1B PLA2G2A PLN PPP1R10 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R13B PPP1R14A PPP1R14B PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3A PPP2R3B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PTPA RAF1 RRAS RRAS2 RYR1 RYR2 RYR3 SOS1 SOS2 SRC TNNI1 TP53BP2 (see all 105) (see less)
2	CDK5 Pathway	QIAGEN	ABL1 ADCY1 ADCY2 ADCY3 AMPH BDNF CABLES1 CACNA1A CAPN1 CDK5 CDK5R1 CTNNB1 DRD1 DRD2 DRD3 DRD4 DRD5 EGR1 FOSB GNA11 GNA12 GNA13 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAS GNAT1 GNAT2 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 HRAS ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 KRAS LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 MAP2K1 MAP2K2 MAPK1 MAPK3 MAPT MRAS NDEL1 NGF NGFR NRAS NTRK2 PAK1 PPP1R10 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R13B PPP1R14A PPP1R14B PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3A PPP2R3B PPP2R5A PPP2R5B PPP2R5C PPP2R5E PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PTPA RAF1 RRAS RRAS2 TP53BP2 UBB UBC UBD (see all 182) (see less)
3	Insulin Receptor Pathway	QIAGEN	AKT1 ARAF BAD BRAF CBL CRK EEF2 EEF2K EIF1AX EIF2B1 EIF2B2 EIF2B3 EIF2B4 EIF2B5 EIF4A1 EIF4A2 EIF4E EIF4EBP1 EIF4EBP2 EIF4EBP3 EIF4G1 EIF4G2 EIF4G3 ELK1 ELK3 ELK4 FLOT1 FLOT2 FOS FOXO3 FYN GRB10 GRB2 GSK3A GSK3B GYS1 HRAS INS INSR IRS1 IRS2 JUN KLK3 KRAS MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAPK1 MAPK10 MAPK12 MAPK3 MAPK6 MAPK7 MAPK8 MAPK9 MRAS MTOR NCK1 NCK2 NRAS PDPK1 PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PPP1R10 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R13B PPP1R14A PPP1R14B PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 RAB4A RAC1 RAC2 RAC3 RAF1 RPS6 RPS6KB1 RRAS RRAS2 SLC2A4 SOS1 SOS2 TP53BP2 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 121) (see less)
4	Erythropoietin Pathway	QIAGEN	AKT1 CSNK2A1 CSNK2A2 CSNK2B ELK1 EPO EPOR FOS GRB2 HRAS JAK2 JUN KRAS MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK4 MAPK6 MAPK7 MAPK8 MAPK9 MRAS NFKB1 NFKBIA NFKBIB NFKBIE NRAS PDPK1 PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PLCG1 PLCG2 PPP1R10 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R13B PPP1R14A PPP1R14B PPP1R15A PPP1R16A PPP1R1A PPP1R1B PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R3A PPP2R3B PPP2R5A PPP2R5B PPP2R5C PPP2R5E PTPA PTPN6 RAF1 RRAS RRAS2 SOS1 SOS2 SRC STAT5A STAT5B TP53BP2 (see all 91) (see less)
5	Insulin Pathway	Tocris	AKT1 AKT2 AKT3 ARAF BRAF CHUK HRAS IGF1R IGF2R IKBKB IKBKG INSR JUN KRAS MAP2K1 MAP2K2 MAPK10 MAPK15 MAPK3 MAPK4 MAPK6 MAPK7 MAPK8 MAPK9 MTOR NRAS PDPK1 PIK3C2A PIK3C2B PIK3C2G PIK3C3 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R4 PIK3R5 PPP1CA PPP1CB PPP1CC PPP1R10 PPP1R11 PPP1R12A PPP1R12B PPP1R12C PPP1R1A PPP1R1B PPP1R1C PPP1R2 PPP1R3A PPP1R3B PPP1R3C PPP1R3D PPP1R3E PPP1R3F PPP1R7 PPP1R8 PPP1R9A PPP1R9B PPP2CA PPP2CB PRKCA PRKCB PRKCG RAF1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 78) (see less)

Gene overlap in member pathways for Beta-Adrenergic Signaling SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	5
2	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	5
3	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	5
4	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	5
5	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	5
6	PPP1R10	Protein Phosphatase 1 Regulatory Subunit 10	Protein Coding	5
7	PPP1R11	Protein Phosphatase 1 Regulatory Inhibitor Subunit 11	Protein Coding	5
8	PPP1R12A	Protein Phosphatase 1 Regulatory Subunit 12A	Protein Coding	5
9	PPP1R12B	Protein Phosphatase 1 Regulatory Subunit 12B	Protein Coding	5
10	PPP1R12C	Protein Phosphatase 1 Regulatory Subunit 12C	Protein Coding	5
11	PPP1R1A	Protein Phosphatase 1 Regulatory Inhibitor Subunit 1A	Protein Coding	5
12	PPP1R1B	Protein Phosphatase 1 Regulatory Inhibitor Subunit 1B	Protein Coding	5
13	PPP1R2	Protein Phosphatase 1 Regulatory Inhibitor Subunit 2	Protein Coding	5
14	PPP1R3A	Protein Phosphatase 1 Regulatory Subunit 3A	Protein Coding	5
15	PPP1R3B	Protein Phosphatase 1 Regulatory Subunit 3B	Protein Coding	5
16	PPP1R3C	Protein Phosphatase 1 Regulatory Subunit 3C	Protein Coding	5
17	PPP1R3D	Protein Phosphatase 1 Regulatory Subunit 3D	Protein Coding	5
18	PPP1R3F	Protein Phosphatase 1 Regulatory Subunit 3F	Protein Coding	5
19	PPP1R7	Protein Phosphatase 1 Regulatory Subunit 7	Protein Coding	5
20	PPP1R8	Protein Phosphatase 1 Regulatory Subunit 8	Protein Coding	5
21	PPP1R9A	Protein Phosphatase 1 Regulatory Subunit 9A	Protein Coding	5
22	PPP1R9B	Protein Phosphatase 1 Regulatory Subunit 9B	Protein Coding	5
23	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	5
24	MRAS	Muscle RAS Oncogene Homolog	Protein Coding	4
25	PPP1R13B	Protein Phosphatase 1 Regulatory Subunit 13B	Protein Coding	4
26	PPP1R14A	Protein Phosphatase 1 Regulatory Inhibitor Subunit 14A	Protein Coding	4
27	PPP1R14B	Protein Phosphatase 1 Regulatory Inhibitor Subunit 14B	Protein Coding	4
28	PPP1R15A	Protein Phosphatase 1 Regulatory Subunit 15A	Protein Coding	4
29	PPP1R16A	Protein Phosphatase 1 Regulatory Subunit 16A	Protein Coding	4
30	PPP2CA	Protein Phosphatase 2 Catalytic Subunit Alpha	Protein Coding	4
31	PPP2CB	Protein Phosphatase 2 Catalytic Subunit Beta	Protein Coding	4
32	RRAS	RAS Related	Protein Coding	4
33	RRAS2	RAS Related 2	Protein Coding	4
34	TP53BP2	Tumor Protein P53 Binding Protein 2	Protein Coding	4
35	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	4
36	ARAF	A-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	3
37	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	3
38	MAP2K3	Mitogen-Activated Protein Kinase Kinase 3	Protein Coding	3
39	MAP2K4	Mitogen-Activated Protein Kinase Kinase 4	Protein Coding	3
40	MAP2K5	Mitogen-Activated Protein Kinase Kinase 5	Protein Coding	3
41	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	3
42	PPP2R1A	Protein Phosphatase 2 Scaffold Subunit Aalpha	Protein Coding	3
43	PPP2R1B	Protein Phosphatase 2 Scaffold Subunit Abeta	Protein Coding	3
44	PPP2R2A	Protein Phosphatase 2 Regulatory Subunit Balpha	Protein Coding	3
45	PPP2R2B	Protein Phosphatase 2 Regulatory Subunit Bbeta	Protein Coding	3
46	PPP2R2C	Protein Phosphatase 2 Regulatory Subunit Bgamma	Protein Coding	3
47	PPP2R3A	Protein Phosphatase 2 Regulatory Subunit B''''Alpha	Protein Coding	3
48	PTPA	Protein Phosphatase 2 Phosphatase Activator	Protein Coding	3
49	PPP2R5A	Protein Phosphatase 2 Regulatory Subunit B''Alpha	Protein Coding	3
50	PPP2R5B	Protein Phosphatase 2 Regulatory Subunit B''Beta	Protein Coding	3
51	PPP2R5C	Protein Phosphatase 2 Regulatory Subunit B''Gamma	Protein Coding	3
52	PPP2R5E	Protein Phosphatase 2 Regulatory Subunit B''Epsilon	Protein Coding	3
53	PPP2R3B	Protein Phosphatase 2 Regulatory Subunit B''''Beta~Name Same As:- HGNC:9310	Protein Coding	3
54	SOS1	SOS Ras/Rac Guanine Nucleotide Exchange Factor 1	Protein Coding	3
55	SOS2	SOS Ras/Rho Guanine Nucleotide Exchange Factor 2	Protein Coding	3
56	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	3
57	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	3
58	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	3
59	MAPK10	Mitogen-Activated Protein Kinase 10	Protein Coding	3
60	MAPK6	Mitogen-Activated Protein Kinase 6	Protein Coding	3
61	MAPK7	Mitogen-Activated Protein Kinase 7	Protein Coding	3
62	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	3
63	MAPK9	Mitogen-Activated Protein Kinase 9	Protein Coding	3
64	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	3
65	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	3
66	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	3
67	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	3
68	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	3
69	PIK3R4	Phosphoinositide-3-Kinase Regulatory Subunit 4	Protein Coding	3
70	ADCY1	Adenylate Cyclase 1	Protein Coding	2
71	ADCY2	Adenylate Cyclase 2	Protein Coding	2
72	ADCY3	Adenylate Cyclase 3	Protein Coding	2
73	GNAI1	G Protein Subunit Alpha I1	Protein Coding	2
74	GNAI2	G Protein Subunit Alpha I2	Protein Coding	2
75	GNAI3	G Protein Subunit Alpha I3	Protein Coding	2
76	GNAS	GNAS Complex Locus	Protein Coding	2
77	GNB1	G Protein Subunit Beta 1	Protein Coding	2
78	GNB2	G Protein Subunit Beta 2	Protein Coding	2
79	GNB3	G Protein Subunit Beta 3	Protein Coding	2
80	GNB4	G Protein Subunit Beta 4	Protein Coding	2
81	GNB5	G Protein Subunit Beta 5	Protein Coding	2
82	GNG10	G Protein Subunit Gamma 10	Protein Coding	2
83	GNG11	G Protein Subunit Gamma 11	Protein Coding	2
84	GNG12	G Protein Subunit Gamma 12	Protein Coding	2
85	GNG13	G Protein Subunit Gamma 13	Protein Coding	2
86	GNG2	G Protein Subunit Gamma 2	Protein Coding	2
87	GNG3	G Protein Subunit Gamma 3	Protein Coding	2
88	GNG4	G Protein Subunit Gamma 4	Protein Coding	2
89	GNG5	G Protein Subunit Gamma 5	Protein Coding	2
90	GNG7	G Protein Subunit Gamma 7	Protein Coding	2
91	GNG8	G Protein Subunit Gamma 8	Protein Coding	2
92	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	2
93	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	2
94	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	2
95	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	2
96	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	2
97	PRKAR1A	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha	Protein Coding	2
98	PRKAR1B	Protein Kinase CAMP-Dependent Type I Regulatory Subunit Beta	Protein Coding	2
99	PRKAR2A	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha	Protein Coding	2
100	PRKAR2B	Protein Kinase CAMP-Dependent Type II Regulatory Subunit Beta	Protein Coding	2
101	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	2
102	ELK1	ETS Transcription Factor ELK1	Protein Coding	2
103	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	2
104	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	2
105	GRB2	Growth Factor Receptor Bound Protein 2	Protein Coding	2
106	INSR	Insulin Receptor	Protein Coding	2
107	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	2
108	PRKCA	Protein Kinase C Alpha	Protein Coding	2
109	PRKCB	Protein Kinase C Beta	Protein Coding	2
110	PRKCG	Protein Kinase C Gamma	Protein Coding	2
111	YWHAB	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Beta	Protein Coding	2
112	YWHAE	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon	Protein Coding	2
113	YWHAG	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma	Protein Coding	2
114	YWHAH	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Eta	Protein Coding	2
115	YWHAQ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta	Protein Coding	2
116	YWHAZ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta	Protein Coding	2
117	MAPK4	Mitogen-Activated Protein Kinase 4	Protein Coding	2
118	ADORA1	Adenosine A1 Receptor	Protein Coding	1
119	ADRB1	Adrenoceptor Beta 1	Protein Coding	1
120	ADRB2	Adrenoceptor Beta 2	Protein Coding	1
121	ATP2A1	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 1	Protein Coding	1
122	ATP2A2	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 2	Protein Coding	1
123	ATP2A3	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 3	Protein Coding	1
124	CACNA1B	Calcium Voltage-Gated Channel Subunit Alpha1 B	Protein Coding	1
125	CACNA1C	Calcium Voltage-Gated Channel Subunit Alpha1 C	Protein Coding	1
126	CACNA1D	Calcium Voltage-Gated Channel Subunit Alpha1 D	Protein Coding	1
127	CACNA1S	Calcium Voltage-Gated Channel Subunit Alpha1 S	Protein Coding	1
128	MAP2K7	Mitogen-Activated Protein Kinase Kinase 7	Protein Coding	1
129	PLA2G1B	Phospholipase A2 Group IB	Protein Coding	1
130	PLA2G2A	Phospholipase A2 Group IIA	Protein Coding	1
131	PLN	Phospholamban	Protein Coding	1
132	PPP2R5D	Protein Phosphatase 2 Regulatory Subunit B''Delta	Protein Coding	1
133	RYR1	Ryanodine Receptor 1	Protein Coding	1
134	RYR2	Ryanodine Receptor 2	Protein Coding	1
135	RYR3	Ryanodine Receptor 3	Protein Coding	1
136	TNNI1	Troponin I1, Slow Skeletal Type	Protein Coding	1
137	ABL1	ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase	Protein Coding	1
138	AMPH	Amphiphysin	Protein Coding	1
139	BDNF	Brain Derived Neurotrophic Factor	Protein Coding	1
140	CABLES1	Cdk5 And Abl Enzyme Substrate 1	Protein Coding	1
141	CACNA1A	Calcium Voltage-Gated Channel Subunit Alpha1 A	Protein Coding	1
142	CAPN1	Calpain 1	Protein Coding	1
143	CDK5	Cyclin Dependent Kinase 5	Protein Coding	1
144	CDK5R1	Cyclin Dependent Kinase 5 Regulatory Subunit 1	Protein Coding	1
145	CTNNB1	Catenin Beta 1	Protein Coding	1
146	DRD1	Dopamine Receptor D1	Protein Coding	1
147	DRD2	Dopamine Receptor D2	Protein Coding	1
148	DRD3	Dopamine Receptor D3	Protein Coding	1
149	DRD4	Dopamine Receptor D4	Protein Coding	1
150	DRD5	Dopamine Receptor D5	Protein Coding	1
151	EGR1	Early Growth Response 1	Protein Coding	1
152	FOSB	FosB Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
153	GNA11	G Protein Subunit Alpha 11	Protein Coding	1
154	GNA12	G Protein Subunit Alpha 12	Protein Coding	1
155	GNA13	G Protein Subunit Alpha 13	Protein Coding	1
156	GNA14	G Protein Subunit Alpha 14	Protein Coding	1
157	GNA15	G Protein Subunit Alpha 15	Protein Coding	1
158	GNAL	G Protein Subunit Alpha L	Protein Coding	1
159	GNAO1	G Protein Subunit Alpha O1	Protein Coding	1
160	GNAT1	G Protein Subunit Alpha Transducin 1	Protein Coding	1
161	GNAT2	G Protein Subunit Alpha Transducin 2	Protein Coding	1
162	GNAZ	G Protein Subunit Alpha Z	Protein Coding	1
163	ITGA1	Integrin Subunit Alpha 1	Protein Coding	1
164	ITGA10	Integrin Subunit Alpha 10	Protein Coding	1
165	ITGA11	Integrin Subunit Alpha 11	Protein Coding	1
166	ITGA2	Integrin Subunit Alpha 2	Protein Coding	1
167	ITGA2B	Integrin Subunit Alpha 2b	Protein Coding	1
168	ITGA3	Integrin Subunit Alpha 3	Protein Coding	1
169	ITGA4	Integrin Subunit Alpha 4	Protein Coding	1
170	ITGA5	Integrin Subunit Alpha 5	Protein Coding	1
171	ITGA6	Integrin Subunit Alpha 6	Protein Coding	1
172	ITGA7	Integrin Subunit Alpha 7	Protein Coding	1
173	ITGA8	Integrin Subunit Alpha 8	Protein Coding	1
174	ITGA9	Integrin Subunit Alpha 9	Protein Coding	1
175	ITGAD	Integrin Subunit Alpha D	Protein Coding	1
176	ITGAE	Integrin Subunit Alpha E	Protein Coding	1
177	ITGAL	Integrin Subunit Alpha L	Protein Coding	1
178	ITGAM	Integrin Subunit Alpha M	Protein Coding	1
179	ITGAV	Integrin Subunit Alpha V	Protein Coding	1
180	ITGAX	Integrin Subunit Alpha X	Protein Coding	1
181	ITGB1	Integrin Subunit Beta 1	Protein Coding	1
182	ITGB2	Integrin Subunit Beta 2	Protein Coding	1
183	ITGB3	Integrin Subunit Beta 3	Protein Coding	1
184	ITGB4	Integrin Subunit Beta 4	Protein Coding	1
185	ITGB5	Integrin Subunit Beta 5	Protein Coding	1
186	ITGB6	Integrin Subunit Beta 6	Protein Coding	1
187	ITGB7	Integrin Subunit Beta 7	Protein Coding	1
188	ITGB8	Integrin Subunit Beta 8	Protein Coding	1
189	LAMA1	Laminin Subunit Alpha 1	Protein Coding	1
190	LAMA2	Laminin Subunit Alpha 2	Protein Coding	1
191	LAMA3	Laminin Subunit Alpha 3	Protein Coding	1
192	LAMA4	Laminin Subunit Alpha 4	Protein Coding	1
193	LAMA5	Laminin Subunit Alpha 5	Protein Coding	1
194	LAMB1	Laminin Subunit Beta 1	Protein Coding	1
195	LAMB2	Laminin Subunit Beta 2	Protein Coding	1
196	LAMB3	Laminin Subunit Beta 3	Protein Coding	1
197	LAMB4	Laminin Subunit Beta 4	Protein Coding	1
198	LAMC1	Laminin Subunit Gamma 1	Protein Coding	1
199	LAMC2	Laminin Subunit Gamma 2	Protein Coding	1
200	LAMC3	Laminin Subunit Gamma 3	Protein Coding	1
201	MAPT	Microtubule Associated Protein Tau	Protein Coding	1
202	NDEL1	NudE Neurodevelopment Protein 1 Like 1	Protein Coding	1
203	NGF	Nerve Growth Factor	Protein Coding	1
204	NGFR	Nerve Growth Factor Receptor	Protein Coding	1
205	NTRK2	Neurotrophic Receptor Tyrosine Kinase 2	Protein Coding	1
206	PSMD6	Proteasome 26S Subunit, Non-ATPase 6	Protein Coding	1
207	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	1
208	PSMA1	Proteasome 20S Subunit Alpha 1	Protein Coding	1
209	PSMA2	Proteasome 20S Subunit Alpha 2	Protein Coding	1
210	PSMA3	Proteasome 20S Subunit Alpha 3	Protein Coding	1
211	PSMA4	Proteasome 20S Subunit Alpha 4	Protein Coding	1
212	PSMA5	Proteasome 20S Subunit Alpha 5	Protein Coding	1
213	PSMA6	Proteasome 20S Subunit Alpha 6	Protein Coding	1
214	PSMA7	Proteasome 20S Subunit Alpha 7	Protein Coding	1
215	PSMB1	Proteasome 20S Subunit Beta 1	Protein Coding	1
216	PSMB10	Proteasome 20S Subunit Beta 10	Protein Coding	1
217	PSMB2	Proteasome 20S Subunit Beta 2	Protein Coding	1
218	PSMB3	Proteasome 20S Subunit Beta 3	Protein Coding	1
219	PSMB4	Proteasome 20S Subunit Beta 4	Protein Coding	1
220	PSMB5	Proteasome 20S Subunit Beta 5	Protein Coding	1
221	PSMB6	Proteasome 20S Subunit Beta 6	Protein Coding	1
222	PSMB7	Proteasome 20S Subunit Beta 7	Protein Coding	1
223	PSMB8	Proteasome 20S Subunit Beta 8	Protein Coding	1
224	PSMB9	Proteasome 20S Subunit Beta 9	Protein Coding	1
225	PSMC1	Proteasome 26S Subunit, ATPase 1	Protein Coding	1
226	PSMC2	Proteasome 26S Subunit, ATPase 2	Protein Coding	1
227	PSMC3	Proteasome 26S Subunit, ATPase 3	Protein Coding	1
228	PSMC4	Proteasome 26S Subunit, ATPase 4	Protein Coding	1
229	PSMC5	Proteasome 26S Subunit, ATPase 5	Protein Coding	1
230	PSMC6	Proteasome 26S Subunit, ATPase 6	Protein Coding	1
231	PSMD1	Proteasome 26S Subunit, Non-ATPase 1	Protein Coding	1
232	PSMD2	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 2	Protein Coding	1
233	PSMD3	Proteasome 26S Subunit, Non-ATPase 3	Protein Coding	1
234	PSMD4	Proteasome 26S Subunit Ubiquitin Receptor, Non-ATPase 4	Protein Coding	1
235	PSMD5	Proteasome 26S Subunit, Non-ATPase 5	Protein Coding	1
236	PSMD7	Proteasome 26S Subunit, Non-ATPase 7	Protein Coding	1
237	UBB	Ubiquitin B	Protein Coding	1
238	UBC	Ubiquitin C	Protein Coding	1
239	UBD	Ubiquitin Like Modifier D	Protein Coding	1
240	KLK3	Kallikrein Related Peptidase 3	Protein Coding	1
241	BAD	BCL2 Associated Agonist Of Cell Death	Protein Coding	1
242	CBL	Cbl Proto-Oncogene	Protein Coding	1
243	CRK	CRK Proto-Oncogene, Adaptor Protein	Protein Coding	1
244	EEF2	Eukaryotic Translation Elongation Factor 2	Protein Coding	1
245	EEF2K	Eukaryotic Elongation Factor 2 Kinase	Protein Coding	1
246	EIF1AX	Eukaryotic Translation Initiation Factor 1A X-Linked	Protein Coding	1
247	EIF2B1	Eukaryotic Translation Initiation Factor 2B Subunit Alpha	Protein Coding	1
248	EIF2B2	Eukaryotic Translation Initiation Factor 2B Subunit Beta	Protein Coding	1
249	EIF2B3	Eukaryotic Translation Initiation Factor 2B Subunit Gamma	Protein Coding	1
250	EIF2B4	Eukaryotic Translation Initiation Factor 2B Subunit Delta	Protein Coding	1
251	EIF2B5	Eukaryotic Translation Initiation Factor 2B Subunit Epsilon	Protein Coding	1
252	EIF4A1	Eukaryotic Translation Initiation Factor 4A1	Protein Coding	1
253	EIF4A2	Eukaryotic Translation Initiation Factor 4A2	Protein Coding	1
254	EIF4E	Eukaryotic Translation Initiation Factor 4E	Protein Coding	1
255	EIF4EBP1	Eukaryotic Translation Initiation Factor 4E Binding Protein 1	Protein Coding	1
256	EIF4EBP2	Eukaryotic Translation Initiation Factor 4E Binding Protein 2	Protein Coding	1
257	EIF4EBP3	Eukaryotic Translation Initiation Factor 4E Binding Protein 3	Protein Coding	1
258	EIF4G1	Eukaryotic Translation Initiation Factor 4 Gamma 1	Protein Coding	1
259	EIF4G2	Eukaryotic Translation Initiation Factor 4 Gamma 2	Protein Coding	1
260	EIF4G3	Eukaryotic Translation Initiation Factor 4 Gamma 3	Protein Coding	1
261	ELK3	ETS Transcription Factor ELK3	Protein Coding	1
262	ELK4	ETS Transcription Factor ELK4	Protein Coding	1
263	FLOT1	Flotillin 1	Protein Coding	1
264	FLOT2	Flotillin 2	Protein Coding	1
265	FOXO3	Forkhead Box O3	Protein Coding	1
266	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
267	GRB10	Growth Factor Receptor Bound Protein 10	Protein Coding	1
268	GSK3A	Glycogen Synthase Kinase 3 Alpha	Protein Coding	1
269	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	1
270	GYS1	Glycogen Synthase 1	Protein Coding	1
271	INS	Insulin	Protein Coding	1
272	IRS1	Insulin Receptor Substrate 1	Protein Coding	1
273	IRS2	Insulin Receptor Substrate 2	Protein Coding	1
274	NCK1	NCK Adaptor Protein 1	Protein Coding	1
275	NCK2	NCK Adaptor Protein 2	Protein Coding	1
276	PRKCD	Protein Kinase C Delta	Protein Coding	1
277	PRKCE	Protein Kinase C Epsilon	Protein Coding	1
278	PRKCH	Protein Kinase C Eta	Protein Coding	1
279	PRKCI	Protein Kinase C Iota	Protein Coding	1
280	PRKD1	Protein Kinase D1	Protein Coding	1
281	PRKD3	Protein Kinase D3	Protein Coding	1
282	PRKCQ	Protein Kinase C Theta	Protein Coding	1
283	PRKCZ	Protein Kinase C Zeta	Protein Coding	1
284	RAB4A	RAB4A, Member RAS Oncogene Family	Protein Coding	1
285	RAC1	Rac Family Small GTPase 1	Protein Coding	1
286	RAC2	Rac Family Small GTPase 2	Protein Coding	1
287	RAC3	Rac Family Small GTPase 3	Protein Coding	1
288	RPS6	Ribosomal Protein S6	Protein Coding	1
289	RPS6KB1	Ribosomal Protein S6 Kinase B1	Protein Coding	1
290	SLC2A4	Solute Carrier Family 2 Member 4	Protein Coding	1
291	CSNK2A1	Casein Kinase 2 Alpha 1	Protein Coding	1
292	CSNK2A2	Casein Kinase 2 Alpha 2	Protein Coding	1
293	CSNK2B	Casein Kinase 2 Beta	Protein Coding	1
294	EPO	Erythropoietin	Protein Coding	1
295	EPOR	Erythropoietin Receptor	Protein Coding	1
296	JAK2	Janus Kinase 2	Protein Coding	1
297	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	1
298	MAPK13	Mitogen-Activated Protein Kinase 13	Protein Coding	1
299	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
300	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
301	NFKBIA	NFKB Inhibitor Alpha	Protein Coding	1
302	NFKBIB	NFKB Inhibitor Beta	Protein Coding	1
303	NFKBIE	NFKB Inhibitor Epsilon	Protein Coding	1
304	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
305	PLCG2	Phospholipase C Gamma 2	Protein Coding	1
306	PTPN6	Protein Tyrosine Phosphatase Non-Receptor Type 6	Protein Coding	1
307	STAT5A	Signal Transducer And Activator Of Transcription 5A	Protein Coding	1
308	STAT5B	Signal Transducer And Activator Of Transcription 5B	Protein Coding	1
309	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	1
310	IGF2R	Insulin Like Growth Factor 2 Receptor	Protein Coding	1
311	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	1
312	IKBKB	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta	Protein Coding	1
313	IKBKG	Inhibitor Of Nuclear Factor Kappa B Kinase Regulatory Subunit Gamma	Protein Coding	1
314	PIK3C2A	Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha	Protein Coding	1
315	PIK3C2B	Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Beta	Protein Coding	1
316	PIK3C2G	Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Gamma	Protein Coding	1
317	PIK3C3	Phosphatidylinositol 3-Kinase Catalytic Subunit Type 3	Protein Coding	1
318	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
319	PIK3CB	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta	Protein Coding	1
320	PIK3CD	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta	Protein Coding	1
321	PIK3CG	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma	Protein Coding	1
322	RPS6KA1	Ribosomal Protein S6 Kinase A1	Protein Coding	1
323	RPS6KA3	Ribosomal Protein S6 Kinase A3	Protein Coding	1
324	RPS6KA2	Ribosomal Protein S6 Kinase A2	Protein Coding	1
325	RPS6KA6	Ribosomal Protein S6 Kinase A6	Protein Coding	1
326	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	1
327	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	1
328	MAPK15	Mitogen-Activated Protein Kinase 15	Protein Coding	1
329	PPP1CA	Protein Phosphatase 1 Catalytic Subunit Alpha	Protein Coding	1
330	PPP1CB	Protein Phosphatase 1 Catalytic Subunit Beta	Protein Coding	1
331	PPP1CC	Protein Phosphatase 1 Catalytic Subunit Gamma	Protein Coding	1
332	PPP1R1C	Protein Phosphatase 1 Regulatory Inhibitor Subunit 1C	Protein Coding	1
333	PPP1R3E	Protein Phosphatase 1 Regulatory Subunit 3E	Protein Coding	1

Disorders associated with Beta-Adrenergic Signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Rasopathy	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NRAS, RAF1, RRAS2, SOS1, SOS2	16.00
2	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NRAS, RAF1, SOS1	10.88
3	Noonan syndrome 1	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NRAS, RAF1, RRAS, RRAS2, SOS1, SOS2	10.76
4	Lung non-small cell carcinoma	Enrichment	BRAF, HRAS, KRAS, MAP2K1, NRAS, PIK3CA	10.64
5	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	8.99
6	Cardiofaciocutaneous syndrome	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	8.99
7	Leukoencephalopathy with vanishing white matter 1	Enrichment	EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5	8.96
8	Leukoencephalopathy with vanishing white matter 5	Enrichment	EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5	8.54
9	Leukoencephalopathy with vanishing white matter	Enrichment	EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5	8.19
10	Nevus, epidermal	Enrichment	HRAS, KRAS, NRAS, PIK3CA	7.46
11	Junctional epidermolysis bullosa	Enrichment	ITGA6, ITGB4, LAMA3, LAMB3, LAMC2	7.30
12	Noonan syndrome 3	Enrichment	HRAS, KRAS, RAF1, SOS1	7.18
13	Melanocytic nevus syndrome, congenital	Enrichment	BRAF, HRAS, NRAS, RAF1	7.16
14	Langerhans cell histiocytosis	Enrichment	BRAF, MAP2K1, NRAS	6.74
15	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	ITGB4, LAMA3, LAMB3, LAMC2	6.34
16	Junctional epidermolysis bullosa non-herlitz type	Enrichment	ITGB4, LAMA3, LAMB3, LAMC2	6.34
17	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	6.14
18	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3, PIK3CA, PIK3R2	6.14
19	Hemimegalencephaly	Enrichment	AKT3, MTOR, PIK3CA	5.74
20	Juvenile myelomonocytic leukemia	Enrichment	CBL, KRAS, NRAS, RRAS	5.55
21	Breast adenocarcinoma	Enrichment	AKT1, KRAS, PIK3CA	5.44
22	Differentiated thyroid carcinoma	Enrichment	BRAF, EIF1AX, HRAS, KRAS, NRAS	5.28
23	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF, HRAS, NRAS	5.20
24	Capillary malformation-arteriovenous malformation 1	Enrichment	KRAS, MAP2K1, PIK3CA	5.20
25	Gallbladder cancer	Enrichment	BRAF, KRAS, PIK3CA	5.20
26	Pilomyxoid astrocytoma	Enrichment	BRAF, KRAS, RAF1	5.20
27	Follicular thyroid carcinoma	Enrichment	BRAF, HRAS, NRAS	5.20
28	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	ABL1, KRAS, NRAS	5.03
29	Arteriovenous malformation	Enrichment	HRAS, MAP2K1, PIK3CA	4.82
30	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, MAP2K1, PIK3CA	4.67
31	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	4.49
32	Type 2 diabetes mellitus	Enrichment	INSR, IRS1, IRS2, PPP1R3A, SLC2A4	4.47
33	Lip and oral cavity carcinoma	Enrichment	BRAF, HRAS, PIK3CA	4.41
34	Epidermolysis bullosa, junctional 1b, severe	Enrichment	LAMA3, LAMB3, LAMC2	4.34
35	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGA2, ITGA2B, ITGB3	4.34
36	Pulmonic stenosis	Enrichment	BRAF, SOS1	4.23
37	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	GNAS, PRKAR1A	4.23
38	Leukemia, chronic myeloid	Enrichment	ABL1, KRAS, NRAS	4.10
39	Cardiac conduction defect	Enrichment	CACNA1C, PLN, RYR2	4.03
40	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	4.01
41	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3CD, PIK3R1	4.01
42	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	4.01
43	Immunodeficiency 14	Enrichment	PIK3CD, PIK3R1	4.01
44	Colorectal cancer	Enrichment	AKT1, BRAF, NRAS, PIK3CA, PIK3R1	3.85
45	Proteasome-associated autoinflammatory syndrome 3	Enrichment	PSMB4, PSMB9	3.75
46	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3, PIK3R2	3.71
47	Noonan syndrome with multiple lentigines	Enrichment	BRAF, RAF1	3.71
48	Erythrocytosis, familial, 1	Enrichment	EPOR, JAK2	3.58
49	Ventricular fibrillation, paroxysmal familial, 1	Enrichment	CACNA1C, RYR2	3.45
50	Malignant hyperthermia	Enrichment	CACNA1S, RYR1	3.45
51	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CBL, YWHAZ	3.33
52	Lung squamous cell carcinoma	Enrichment	KRAS, PIK3CA	3.32
53	Bleeding disorder, platelet-type, 16	Enrichment	ITGA2B, ITGB3	3.27
54	Proteasome-associated autoinflammatory syndrome 1	Enrichment	PSMB4, PSMB8	3.27
55	Proteosome-associated autoinflammatory syndrome	Enrichment	PSMB4, PSMB8	3.27
56	Anastomosing haemangioma	Enrichment	GNA11, GNA14	3.27
57	Heart conduction disease	Enrichment	CACNA1C, RYR2	3.23
58	Bladder cancer	Enrichment	HRAS, KRAS, PIK3CA	3.22
59	Overgrowth syndrome	Enrichment	MTOR, PIK3R1	3.17
60	Multiple sclerosis	Enrichment	ITGB4, LAMA5, LAMB1	3.11
61	Lung cancer	Enrichment	BRAF, KRAS, PIK3CA	3.09
62	Breast cancer	Enrichment	AKT1, JUN, KRAS, PIK3CA	3.04
63	Myelofibrosis	Enrichment	JAK2, SRC	3.04
64	Achromatopsia 4	Enrichment	GNAI3, GNAT2	2.98
65	Ventricular septal defect	Enrichment	BRAF, RPS6KA3	2.94
66	Cowden syndrome	Enrichment	AKT1, PIK3CA	2.94
67	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3CD, PIK3R1	2.85
68	Myeloma, multiple	Enrichment	BRAF, EIF1AX, KRAS, PIK3R2	2.81
69	Long qt syndrome	Enrichment	CACNA1C, CACNA1S, RYR2	2.76
70	Specific learning disability	Enrichment	RPS6KA3, YWHAG	2.76
71	Epidermolysis bullosa	Enrichment	ITGA6, LAMB3	2.76
72	Hereditary breast carcinoma	Enrichment	AKT1, KRAS, PIK3CA	2.69
73	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	2.69
74	Primary hyperaldosteronism	Enrichment	BRAF, GNAS	2.69
75	Hydrops fetalis	Enrichment	RYR1, RYR3	2.69
76	Meningioma	Enrichment	AKT1, PIK3CA	2.68
77	Leukemia, acute myeloid	Enrichment	JAK2, KRAS, NRAS	2.62
78	Nk-cell enteropathy	Enrichment	IGF1R, PIK3CB	2.61
79	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGA6, ITGB4	2.59
80	Adrenocortical carcinoma	Enrichment	CTNNB1, PRKAR1A	2.59
81	Lung cancer susceptibility 3	Enrichment	BRAF, KRAS	2.55
82	Attention deficit-hyperactivity disorder	Enrichment	DRD4, DRD5, GNB5	2.52
83	Skin disease	Enrichment	ITGB4, LAMB3, LAMC2	2.52
84	Lynch syndrome	Enrichment	KRAS, PIK3CA	2.49
85	Glanzmann thrombasthenia 1	Enrichment	ITGA2B, ITGB3	2.44
86	Dandy-walker syndrome	Enrichment	BRAF, PPP1CB	2.38
87	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	PLN, RYR2	2.29
88	Arteriovenous malformations of the brain	Enrichment	BRAF, KRAS	2.28
89	Macrodactyly	Enrichment	PIK3CA	2.24
90	Proteus syndrome	Enrichment	AKT1	2.24
91	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	2.24
92	Donohue syndrome	Enrichment	INSR	2.24
93	Coffin-lowry syndrome	Enrichment	RPS6KA3	2.24
94	Oculoectodermal syndrome	Enrichment	KRAS	2.24
95	Pallister-killian syndrome	Enrichment	ARAF	2.24
96	Incontinentia pigmenti	Enrichment	IKBKG	2.24
97	Hyperinsulinemic hypoglycemia, familial, 5	Enrichment	INSR	2.24
98	Autoinflammatory disease, systemic, x-linked	Enrichment	IKBKG	2.24
99	Noonan syndrome 5	Enrichment	RAF1	2.24
100	Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities	Enrichment	INSR	2.24
101	Diabetes mellitus, insulin-resistant, with acanthosis nigricans	Enrichment	INSR	2.24
102	Melorheostosis, isolated	Enrichment	MAP2K1	2.24
103	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.24
104	Noonan syndrome 7	Enrichment	BRAF	2.24
105	Leopard syndrome 3	Enrichment	BRAF	2.24
106	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.24
107	Cowden syndrome 5	Enrichment	PIK3CA	2.24
108	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.24
109	Melanosis, neurocutaneous	Enrichment	NRAS	2.24
110	Noonan syndrome 6	Enrichment	NRAS	2.24
111	Fetal encasement syndrome	Enrichment	CHUK	2.24
112	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	2.24
113	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.24
114	Immunodeficiency 15b	Enrichment	IKBKB	2.24
115	Immunodeficiency 15a	Enrichment	IKBKB	2.24
116	Short syndrome	Enrichment	PIK3R1	2.24
117	Ectodermal dysplasia and immunodeficiency 1	Enrichment	IKBKG	2.24
118	Oculoskeletodental syndrome	Enrichment	PIK3C2A	2.24
119	Intellectual developmental disorder, x-linked 19	Enrichment	RPS6KA3	2.24
120	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	2.24
121	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	2.24
122	Lymphangioma	Enrichment	BRAF	2.24
123	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.24
124	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.24
125	Phace association	Enrichment	BRAF	2.24
126	Spinocerebellar ataxia 14	Enrichment	PRKCG	2.24
127	Melorheostosis	Enrichment	MAP2K1	2.24
128	Leopard syndrome 2	Enrichment	RAF1	2.24
129	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.24
130	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	2.24
131	Cowden syndrome 6	Enrichment	AKT1	2.24
132	Immunodeficiency 14b, autosomal recessive	Enrichment	PIK3CD	2.24
133	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.24
134	Immunodeficiency 97 with autoinflammation	Enrichment	PIK3CG	2.24
135	Developmental and epileptic encephalopathy 56	Enrichment	YWHAG	2.24
136	Noonan syndrome-like disorder with loose anagen hair 2	Enrichment	PPP1CB	2.24
137	Bartsocas-papas syndrome 2	Enrichment	CHUK	2.24
138	Trigonitis	Enrichment	RAF1	2.24
139	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.24
140	Symptomatic form of coffin-lowry syndrome in female carriers	Enrichment	RPS6KA3	2.24
141	Hypospadias	Enrichment	PIK3CA	2.24
142	Capillary hemangioma	Enrichment	AKT3	2.24
143	Congenital pulmonary airway malformation	Enrichment	KRAS	2.24
144	Rare venous malformation	Enrichment	PIK3CA	2.24
145	Diaphragmatic eventration	Enrichment	PIK3CA	2.24
146	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.24
147	Syringocystadenoma papilliferum	Enrichment	BRAF	2.24
148	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	2.24
149	Rare combined vascular malformation	Enrichment	PIK3CA	2.24
150	Ganglioglioma	Enrichment	BRAF	2.24
151	Cavernous lymphangioma	Enrichment	PIK3CA	2.24
152	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.24
153	Nongerminomatous germ cell tumor	Enrichment	BRAF	2.24
154	Phace syndrome	Enrichment	BRAF	2.24
155	Oculocerebrodental syndrome	Enrichment	PIK3C2A	2.24
156	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.24
157	Classic hairy cell leukemia	Enrichment	BRAF	2.24
158	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.24
159	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.24
160	Distal 17p13.3 microdeletion syndrome	Enrichment	YWHAE	2.24
161	Macrodactyly of toe	Enrichment	PIK3CA	2.24
162	Neurocutaneous melanocytosis	Enrichment	NRAS	2.24
163	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	2.24
164	Microcephaly	Enrichment	ABL1, CTNNB1, GNAO1, GNB1, MAPK1, PSMC3	2.20
165	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	RYR1, RYR2	2.18
166	Noonan syndrome 4	Enrichment	SOS1	2.17
167	Spinocerebellar ataxia 12	Enrichment	PPP2R2B	2.17
168	Noonan syndrome 9	Enrichment	SOS2	2.17
169	Microvascular complications of diabetes 2	Enrichment	EPO	2.17
170	Noonan syndrome 11	Enrichment	MRAS	2.17
171	Noonan syndrome 13	Enrichment	MAPK1	2.17
172	Growth hormone insensitivity syndrome with immune dysregulation 2, autosomal dominant	Enrichment	STAT5B	2.17
173	Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development	Enrichment	PTPA	2.17
174	Houge-janssens syndrome 4	Enrichment	PPP2R5C	2.17
175	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.17
176	Houge-janssens syndrome 2	Enrichment	PPP2R1A	2.17
177	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	2.17
178	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	2.17
179	Erythrocytosis, familial, 5	Enrichment	EPO	2.17
180	Thrombocytopenia 6	Enrichment	SRC	2.17
181	Okur-chung neurodevelopmental syndrome	Enrichment	CSNK2A1	2.17
182	Craniodigital syndrome and intellectual disability syndrome	Enrichment	CSNK2B	2.17
183	Vegetative pyoderma gangrenosum	Enrichment	PTPN6	2.17
184	Bullous pyoderma gangrenosum	Enrichment	PTPN6	2.17
185	Pustular pyoderma gangrenosum	Enrichment	PTPN6	2.17
186	Ppp2r1a-related neurodevelopmental disorder	Enrichment	PPP2R1A	2.17
187	Classic pyoderma gangrenosum	Enrichment	PTPN6	2.17
188	Hepatocellular carcinoma	Enrichment	IGF2R, PIK3CA	2.15
189	Amelogenesis imperfecta, type ie	Enrichment	ITGB6, LAMB3	2.12
190	Autosomal dominant macrothrombocytopenia	Enrichment	ITGA2B, ITGB3	2.12
191	Acrodysostosis 1 with or without hormone resistance	Enrichment	PRKAR1A	2.11
192	Thyrotoxic periodic paralysis 1	Enrichment	CACNA1S	2.11
193	Pseudohypoparathyroidism, type ic	Enrichment	GNAS	2.11
194	Carney complex, type 1	Enrichment	PRKAR1A	2.11
195	Resting heart rate, variation in	Enrichment	ADRB1	2.11
196	Osseous heteroplasia, progressive	Enrichment	GNAS	2.11
197	Deafness, autosomal recessive 44	Enrichment	ADCY1	2.11
198	Ventricular tachycardia, familial	Enrichment	GNAI2	2.11
199	Acth-independent macronodular adrenal hyperplasia 1	Enrichment	GNAS	2.11
200	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	2.11
201	Congenital myopathy 20	Enrichment	RYR3	2.11
202	Pituitary adenoma 3, multiple types	Enrichment	GNAS	2.11
203	Congenital myopathy 18	Enrichment	CACNA1S	2.11
204	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	2.11
205	Neurodevelopmental disorder with hypotonia, impaired speech, and behavioral abnormalities	Enrichment	GNAI1	2.11
206	Myxoma, intracardiac	Enrichment	PRKAR1A	2.11
207	Primary aldosteronism, seizures, and neurologic abnormalities	Enrichment	CACNA1D	2.11
208	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	2.11
209	Brugada syndrome 3	Enrichment	CACNA1C	2.11
210	Malignant hyperthermia 5	Enrichment	CACNA1S	2.11
211	Sinoatrial node dysfunction and deafness	Enrichment	CACNA1D	2.11
212	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	2.11
213	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	2.11
214	Disorders of gnas inactivation	Enrichment	GNAS	2.11
215	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	2.11
216	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	2.11
217	Sick sinus syndrome 4	Enrichment	GNB2	2.11
218	Short sleep, familial natural, 2	Enrichment	ADRB1	2.11
219	Congenital myopathy with myasthenic-like onset	Enrichment	RYR1	2.11
220	Rhabdomyolysis 2	Enrichment	ATP2A2	2.11
221	Prkar1b-related neurodegenerative dementia with intermediate filaments	Enrichment	PRKAR1B	2.11
222	Atypical timothy syndrome	Enrichment	CACNA1C	2.11
223	Aldosterone-producing adenoma with seizures and neurological abnormalities	Enrichment	CACNA1D	2.11
224	Monostotic fibrous dysplasia	Enrichment	GNAS	2.11
225	Timothy syndrome type 2	Enrichment	CACNA1C	2.11
226	Periodic paralysis with transient compartment-like syndrome	Enrichment	CACNA1S	2.11
227	Mazabraud syndrome	Enrichment	GNAS	2.11
228	Calf-predominant weakness-gastrocnemius medialis atrophy-distal myopathy	Enrichment	RYR1	2.11
229	Timothy syndrome type 1	Enrichment	CACNA1C	2.11
230	Cacna1c-related disorders	Enrichment	CACNA1C	2.11
231	Benign samaritan congenital myopathy	Enrichment	RYR1	2.11
232	Rhabdomyosarcoma	Enrichment	CBL, HRAS	2.06
233	Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis	Enrichment	RAC2	2.05
234	Parkinson disease 18, autosomal dominant	Enrichment	EIF4G1	2.05
235	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	2.05
236	Leukoencephalopathy with vanishing white matter 3	Enrichment	EIF2B3	2.05
237	Neurodevelopmental disorder with structural brain anomalies and dysmorphic facies	Enrichment	RAC3	2.05
238	Autism 19	Enrichment	EIF4E	2.05
239	Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia	Enrichment	RAC2	2.05
240	Spinocerebellar ataxia 26	Enrichment	EEF2	2.05
241	Neurodevelopmental disorder with hypotonia and speech delay, with or without seizures	Enrichment	EIF4A2	2.05
242	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	2.05
243	Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia	Enrichment	RAC2	2.05
244	Leukoencephalopathy with vanishing white matter 2	Enrichment	EIF2B2	2.05
245	Infantile lad-like disease due to rac2 deficiency	Enrichment	RAC2	2.05
246	Reticular dysgenesis-like severe combined immunodeficiency	Enrichment	RAC2	2.05
247	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.05
248	Silver-russell syndrome due to maternal uniparental disomy of chromosome 7	Enrichment	GRB10	2.05
249	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	2.05
250	Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome	Enrichment	RAC2	2.05
251	Congenital myopathy	Enrichment	CACNA1S, RYR1	2.03
252	Centronuclear myopathy	Enrichment	CACNA1S, RYR1	1.95
253	Scoliosis, isolated 1	Enrichment	MAPK7	1.94
254	Costello syndrome	Enrichment	HRAS	1.94
255	Immunodeficiency 33	Enrichment	IKBKG	1.94
256	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	1.94
257	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	INSR	1.94
258	Keratosis, seborrheic	Enrichment	PIK3CA	1.94
259	Encephalocraniocutaneous lipomatosis	Enrichment	KRAS	1.94
260	Roifman-chitayat syndrome	Enrichment	PIK3CD	1.94
261	Noonan syndrome 8	Enrichment	PIK3CA	1.94
262	Spermatogenic failure 17	Enrichment	PIK3C2G	1.94
263	Genitourinary and/or brain malformation syndrome	Enrichment	PPP1R12A	1.94
264	Cebalid syndrome	Enrichment	MTOR	1.94
265	Noonan syndrome-like disorder with loose anagen hair	Enrichment	PPP1CB	1.94
266	Senior-loken syndrome 7	Enrichment	AKT3	1.94
267	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	1.94
268	Ectodermal dysplasia and immune deficiency	Enrichment	IKBKG	1.94
269	Immune system disease	Enrichment	PIK3CD	1.94
270	Bardet-biedl syndrome 16	Enrichment	AKT3	1.94
271	Smith-kingsmore syndrome	Enrichment	MTOR	1.94
272	Glucosephosphate dehydrogenase deficiency	Enrichment	IKBKG	1.94
273	Houge-janssens syndrome 3	Enrichment	PPP2CA	1.94
274	Tafro syndrome	Enrichment	MAP2K2	1.94
275	Wooly hair nevus	Enrichment	HRAS	1.94
276	Fibromatosis, gingival, 1	Enrichment	SOS1	1.87
277	Growth hormone insensitivity syndrome with immune dysregulation 1, autosomal recessive	Enrichment	STAT5B	1.87
278	Ectodermal dysplasia and immunodeficiency 2	Enrichment	NFKBIA	1.87
279	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	1.87
280	Thrombocythemia 3	Enrichment	JAK2	1.87
281	Diamond-blackfan anemia-like	Enrichment	EPO	1.87
282	Noonan syndrome 12	Enrichment	RRAS2	1.87
283	Poirier-bienvenu neurodevelopmental syndrome	Enrichment	CSNK2B	1.87
284	Polycythemia	Enrichment	JAK2	1.87
285	Hypereosinophilic syndrome	Enrichment	JAK2	1.87
286	Common variable immunodeficiency 12	Enrichment	NFKB1	1.87
287	Laron syndrome with immunodeficiency	Enrichment	STAT5B	1.87
288	Hypocalciuric hypercalcemia, familial, type ii	Enrichment	GNA11	1.87
289	Systemic lupus erythematosus 6	Enrichment	ITGAM	1.87
290	Blepharospasm, benign essential	Enrichment	DRD5	1.87
291	Cardiomyopathy, dilated, 1jj	Enrichment	LAMA4	1.87
292	Tremor, hereditary essential, 1	Enrichment	DRD3	1.87
293	Lissencephaly 5	Enrichment	LAMB1	1.87
294	Neurodevelopmental disorder with involuntary movements	Enrichment	GNAO1	1.87
295	Lissencephaly 7 with cerebellar hypoplasia	Enrichment	CDK5	1.87
296	Neurodevelopmental disorder with microcephaly, hypotonia, and absent language	Enrichment	PSMB1	1.87
297	Nephrotic syndrome, type 26	Enrichment	LAMA5	1.87
298	Developmental and epileptic encephalopathy 58	Enrichment	NTRK2	1.87
299	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	1.87
300	Fetomaternal alloimmune thrombocytopenia 2	Enrichment	ITGA2B	1.87
301	Parkinson-dementia syndrome	Enrichment	MAPT	1.87
302	Supranuclear palsy, progressive, 1	Enrichment	MAPT	1.87
303	Developmental and epileptic encephalopathy 17	Enrichment	GNAO1	1.87
304	Deafness, cataract, impaired intellectual development, and polyneuropathy	Enrichment	PSMC3	1.87
305	Progressive supranuclear palsy	Enrichment	MAPT	1.87
306	Night blindness, congenital stationary, autosomal dominant 3	Enrichment	GNAT1	1.87
307	Cortical malformations, occipital	Enrichment	LAMC3	1.87
308	Dystonia 25	Enrichment	GNAL	1.87
309	Night blindness, congenital stationary, type 1g	Enrichment	GNAT1	1.87
310	Hypocalcemia, autosomal dominant 2	Enrichment	GNA11	1.87
311	Proteasome-associated autoinflammatory syndrome 6	Enrichment	PSMB9	1.87
312	Obesity, hyperphagia, and developmental delay	Enrichment	NTRK2	1.87
313	Classic progressive supranuclear palsy syndrome	Enrichment	MAPT	1.87
314	Bent bone dysplasia syndrome 2	Enrichment	LAMA5	1.87
315	Adenoid ameloblastoma	Enrichment	CTNNB1	1.87
316	Amelogenesis imperfecta, type ih	Enrichment	ITGB6	1.87
317	Occipital pachygyria and polymicrogyria	Enrichment	LAMC3	1.87
318	Atypical progressive supranuclear palsy syndrome	Enrichment	MAPT	1.87
319	Autonomic nervous system disease	Enrichment	DRD4	1.87
320	Fetomaternal alloimmune thrombocytopenia 3	Enrichment	ITGA2	1.87
321	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	1.87
322	Sporadic hemiplegic migraine	Enrichment	CACNA1A	1.87
323	Gnao1-related disorder	Enrichment	GNAO1	1.87
324	Phakomatosis cesiomarmorata	Enrichment	GNA11	1.87
325	Kaposiform hemangioendothelioma	Enrichment	GNA14	1.87
326	Lama5-related multisystemic syndrome	Enrichment	LAMA5	1.87
327	Microcystic stromal tumor	Enrichment	CTNNB1	1.87
328	Laminin subunit alpha 2-related muscular dystrophy	Enrichment	LAMA2	1.87
329	Benign paroxysmal torticollis of infancy	Enrichment	CACNA1A	1.87
330	Blepharospasm	Enrichment	DRD5	1.87
331	Non-immune hydrops fetalis	Enrichment	HRAS, KRAS	1.87
332	Cardiomyopathy, familial hypertrophic, 1	Enrichment	CACNA1C, RAF1	1.83
333	Malignant hyperthermia 1	Enrichment	RYR1	1.81
334	Acrokeratosis verruciformis	Enrichment	ATP2A2	1.81
335	Pseudohypoparathyroidism, type ia	Enrichment	GNAS	1.81
336	Ventricular arrhythmias due to cardiac ryanodine receptor calcium release deficiency syndrome	Enrichment	RYR2	1.81
337	Amelogenesis imperfecta, type ig	Enrichment	PRKAR1A	1.81
338	Pituitary adenoma 4, acth-secreting	Enrichment	GNAI2	1.81
339	Brody disease	Enrichment	ATP2A1	1.81
340	Timothy syndrome	Enrichment	CACNA1C	1.81
341	Pseudopseudohypoparathyroidism	Enrichment	GNAS	1.81
342	Cardiomyopathy, dilated, 1p	Enrichment	PLN	1.81
343	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	1.81
344	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	1.81
345	Cardiomyopathy, familial hypertrophic, 18	Enrichment	PLN	1.81
346	Houge-janssens syndrome 1	Enrichment	PPP2R5D	1.81
347	Long qt syndrome 8	Enrichment	CACNA1C	1.81
348	Marbach-schaaf neurodevelopmental syndrome	Enrichment	PRKAR1B	1.81
349	Usher syndrome, type iv	Enrichment	PRKAR1A	1.81
350	Ventricular tachycardia, catecholaminergic polymorphic, 2	Enrichment	RYR2	1.81
351	King-denborough syndrome	Enrichment	RYR1	1.81
352	Acrodysostosis	Enrichment	PRKAR1A	1.81
353	Pseudohypoparathyroidism	Enrichment	GNAS	1.81
354	Body mass index quantitative trait locus 19	Enrichment	ADCY3	1.81
355	Fibrolamellar carcinoma	Enrichment	PRKACA	1.81
356	Ciliary dyskinesia, primary, 18	Enrichment	PRKAR1B	1.81
357	Hypopituitarism	Enrichment	GNAI2	1.81
358	Congenital disorder of glycosylation, type iw, autosomal dominant	Enrichment	CACNA1D	1.81
359	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	1.81
360	Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements	Enrichment	CACNA1B	1.81
361	Exercise-induced malignant hyperthermia	Enrichment	RYR1	1.81
362	Isolated primary pigmented nodular adrenocortical disease	Enrichment	PRKAR1A	1.81
363	Acth-independent macronodular adrenal hyperplasia	Enrichment	GNAS	1.81
364	Cerebral visual impairment	Enrichment	GNB1	1.81
365	Ataxia-telangiectasia	Enrichment	BRAF	1.77
366	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.77
367	Miller-dieker lissencephaly syndrome	Enrichment	YWHAE	1.77
368	Chromosome 17p13.3, centromeric, duplication syndrome	Enrichment	YWHAE	1.77
369	Tethered spinal cord syndrome	Enrichment	BRAF	1.77
370	Spermatocytoma	Enrichment	HRAS	1.77
371	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	1.77
372	Keratoacanthoma	Enrichment	PIK3CA	1.77
373	Ovarian germ cell cancer	Enrichment	CBL	1.75
374	Maturity-onset diabetes of the young, type 10	Enrichment	INS	1.75
375	Hyperproinsulinemia	Enrichment	INS	1.75
376	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	1.75
377	Leukoencephalopathy with vanishing white matter 4	Enrichment	EIF2B4	1.75
378	Glycogen storage disease 0, muscle	Enrichment	GYS1	1.75
379	Diabetes mellitus, permanent neonatal, 4	Enrichment	INS	1.75
380	Glycogen storage disease due to muscle and heart glycogen synthase deficiency	Enrichment	GYS1	1.75
381	Malignant germ cell tumor of ovary	Enrichment	CBL	1.75
382	Nephrotic syndrome	Enrichment	ITGA3, LAMA5, LAMB2	1.70
383	Prognathism, mandibular	Enrichment	CSNK2B	1.70
384	Polycythemia vera	Enrichment	JAK2	1.70
385	Nuchal bleb, familial	Enrichment	SOS1	1.70
386	Nasopharyngeal carcinoma	Enrichment	NFKBIA	1.70
387	Neutrophilic dermatosis, acute febrile	Enrichment	PTPN6	1.70
388	Primary polycythemia	Enrichment	EPOR	1.70
389	Breast implant-associated anaplastic large cell lymphoma	Enrichment	JAK2	1.70
390	Ovarian cancer	Enrichment	AKT1, KRAS, PIK3CA	1.69
391	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	1.64
392	Thyroid cancer, nonmedullary, 1	Enrichment	BRAF	1.64
393	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.64
394	Focal cortical dysplasia, type ii	Enrichment	MTOR	1.64
395	Lung sarcomatoid carcinoma	Enrichment	KRAS	1.64
396	Hereditary ataxia	Enrichment	PRKCG	1.64
397	Cerebrovascular disease	Enrichment	PIK3CA	1.64
398	Craniopharyngioma	Enrichment	BRAF	1.64
399	Pilocytic astrocytoma	Enrichment	KRAS	1.64
400	Newborn respiratory distress syndrome	Enrichment	BRAF	1.64
401	Epidermolytic nevus	Enrichment	HRAS	1.64
402	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.64
403	Isolated focal cortical dysplasia type ii	Enrichment	MTOR	1.64
404	Darier-white disease	Enrichment	ATP2A2	1.64
405	Mccune-albright syndrome	Enrichment	GNAS	1.64
406	Lynch syndrome 5	Enrichment	RYR1	1.64
407	Neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures	Enrichment	CACNA1C	1.64
408	Bronchopulmonary dysplasia	Enrichment	RYR1	1.64
409	Intrinsic cardiomyopathy	Enrichment	PLN	1.64
410	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	GNAS	1.64
411	Thyrotoxic periodic paralysis	Enrichment	CACNA1S	1.64
412	Dilated cardiomyopathy	Enrichment	BRAF, PLN, RAF1	1.62
413	Gastric cancer	Enrichment	KRAS, PIK3CA	1.60
414	Type 1 diabetes mellitus 2	Enrichment	INS	1.58
415	Heparin cofactor ii deficiency	Enrichment	EIF4G3	1.58
416	Budd-chiari syndrome	Enrichment	JAK2	1.58
417	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.58
418	Congenital generalized lipodystrophy	Enrichment	FOS	1.58
419	Enophthalmos	Enrichment	CSNK2B	1.58
420	Syndactyly	Enrichment	CSNK2B	1.58
421	Gingival fibromatosis	Enrichment	SOS1	1.58
422	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	SOS2	1.58
423	Amelogenesis imperfecta, type ia	Enrichment	LAMB3	1.57
424	Leukocyte adhesion deficiency, type i	Enrichment	ITGB2	1.57
425	Epidermolysis bullosa, junctional 2c, laryngoonychocutaneous	Enrichment	LAMA3	1.57
426	Cutis marmorata telangiectatica congenita	Enrichment	GNA11	1.57
427	Myasthenic syndrome, congenital, 5	Enrichment	LAMB2	1.57
428	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.57
429	Alternating hemiplegia of childhood 1	Enrichment	CACNA1A	1.57
430	Pick disease of brain	Enrichment	MAPT	1.57
431	Leukocyte adhesion deficiency, type iii	Enrichment	ITGB2	1.57
432	Lissencephaly 1	Enrichment	LAMB1	1.57
433	Angioma, tufted	Enrichment	GNA14	1.57
434	Pierson syndrome	Enrichment	LAMB2	1.57
435	Spastic paraplegia 76, autosomal recessive	Enrichment	CAPN1	1.57
436	Proteasome-associated autoinflammatory syndrome 5	Enrichment	PSMB10	1.57
437	Epidermolysis bullosa, junctional 3b, severe	Enrichment	LAMC2	1.57
438	Epidermolysis bullosa, junctional 3a, intermediate	Enrichment	LAMC2	1.57
439	Congenital heart defects and skeletal malformations syndrome	Enrichment	ABL1	1.57
440	Epidermolysis bullosa, junctional 2a, intermediate	Enrichment	LAMA3	1.57
441	Epidermolysis bullosa, junctional 5a, intermediate	Enrichment	ITGB4	1.57
442	Immunodeficiency 121 with autoinflammation	Enrichment	PSMB10	1.57
443	Birk-aharoni syndrome	Enrichment	PSMC1	1.57
444	Nephrotic syndrome, type 5, with or without ocular abnormalities	Enrichment	LAMB2	1.57
445	Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome	Enrichment	ITGA3	1.57
446	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	1.57
447	Autosomal dominant hypocalcemia	Enrichment	GNA11	1.57
448	Epidermolysis bullosa, junctional 2b, severe	Enrichment	LAMA3	1.57
449	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.57
450	Localized junctional epidermolysis bullosa, non-herlitz type	Enrichment	ITGB4	1.57
451	Teratoma	Enrichment	CTNNB1	1.57
452	Progressive bulbar palsy	Enrichment	CACNA1A	1.57
453	Submucosal cleft palate	Enrichment	UBB	1.57
454	Phakomatosis cesioflammea	Enrichment	GNA11	1.57
455	Cleft hard palate	Enrichment	UBB	1.57
456	Capillary malformations, congenital	Enrichment	PIK3CA	1.55
457	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	IKBKG	1.55
458	Insulin-like growth factor i	Enrichment	IGF1R	1.55
459	Endometrial stromal sarcoma	Enrichment	YWHAE	1.55
460	Body mass index quantitative trait locus 11	Enrichment	ADCY3, BDNF, GNAS	1.53
461	Left ventricular noncompaction	Enrichment	RAF1, RYR2	1.52
462	Congenital myopathy 1a, autosomal dominant, with malignant hyperthermia	Enrichment	RYR1	1.51
463	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	1.51
464	Myopathy, centronuclear, 2	Enrichment	RYR1	1.51
465	Sacral defect with anterior meningocele	Enrichment	RYR1	1.51
466	Pseudohypoparathyroidism, type ib	Enrichment	GNAS	1.51
467	Amyotrophy, monomelic	Enrichment	RYR3	1.51
468	Auriculocondylar syndrome 1	Enrichment	GNAI3	1.51
469	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	1.51
470	Carney complex variant	Enrichment	PRKAR1A	1.51
471	Arrhythmogenic right ventricular dysplasia, familial, 10	Enrichment	PRKAR1A	1.51
472	Intellectual developmental disorder, autosomal dominant 26	Enrichment	RYR1	1.51
473	Congenital myopathy 1a	Enrichment	RYR1	1.51
474	Paroxysmal familial ventricular fibrillation	Enrichment	RYR2	1.51
475	Familial sick sinus syndrome	Enrichment	GNB2	1.51
476	Myeloproliferative neoplasm	Enrichment	JAK2	1.48
477	Histiocytoid hemangioma	Enrichment	FOS	1.48
478	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.47
479	Cowden syndrome 1	Enrichment	PIK3CA	1.47
480	Hemihyperplasia, isolated	Enrichment	PIK3CA	1.47
481	Wilms tumor 5	Enrichment	BRAF	1.47
482	46,xy disorder of sex development	Enrichment	INSR	1.47
483	Kidney clear cell sarcoma	Enrichment	YWHAE	1.47
484	Myocardial infarction	Enrichment	ITGB3, PSMA6	1.46
485	Neonatal diabetes mellitus	Enrichment	INS	1.45
486	Hypertelorism	Enrichment	PIK3CA, RPS6KA3	1.44
487	Cerebral palsy	Enrichment	CACNA1C, GNB1	1.44
488	Autism spectrum disorder	Enrichment	CSNK2A1, CSNK2B, MAP2K1	1.43
489	Congenital stationary night blindness	Enrichment	GNAT1, GNB3	1.42
490	Congenital myopathy 1b, autosomal recessive	Enrichment	RYR1	1.42
491	Cardiac arrest	Enrichment	PLN	1.42
492	Renal cell carcinoma, papillary, 1	Enrichment	MTOR	1.40
493	Megacolon	Enrichment	AKT3	1.40
494	Autosomal dominant secondary polycythemia	Enrichment	EPO	1.40
495	Desmoid disease, hereditary	Enrichment	CTNNB1	1.40
496	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3	1.40
497	Uvula, bifid	Enrichment	UBB	1.40
498	Cleft soft palate	Enrichment	UBB	1.40
499	Muscular dystrophy, congenital merosin-deficient, 1a	Enrichment	LAMA2	1.40
500	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.40
501	Muscular dystrophy, congenital, due to integrin alpha-7 deficiency	Enrichment	ITGA7	1.40
502	Anus, imperforate	Enrichment	CTNNB1	1.40
503	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.40
504	Epidermolysis bullosa, junctional 6, with pyloric atresia	Enrichment	ITGA6	1.40
505	Desmoid tumor	Enrichment	CTNNB1	1.40
506	Poretti-boltshauser syndrome	Enrichment	LAMA1	1.40
507	T-cell acute lymphoblastic leukemia	Enrichment	ABL1	1.40
508	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	1.40
509	Alopecia - intellectual disability syndrome	Enrichment	ITGB6	1.40
510	Thyroid hemiagenesis	Enrichment	PSMD3	1.40
511	Hereditary episodic ataxia	Enrichment	CACNA1A	1.40
512	Lama2-related muscular dystrophy	Enrichment	LAMA2	1.40
513	Aggressive systemic mastocytosis	Enrichment	CBL	1.36
514	Gastroesophageal reflux	Enrichment	RPS6KA3	1.35
515	Lymphoma, non-hodgkin, familial	Enrichment	BRAF	1.35
516	Orthostatic intolerance	Enrichment	RPS6KA3	1.35
517	Lennox-gastaut syndrome	Enrichment	MAPK10	1.35
518	Hypokalemic periodic paralysis, type 1	Enrichment	CACNA1S	1.34
519	Myopathy, centronuclear, 1	Enrichment	RYR1	1.34
520	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	RYR2	1.34
521	Essential thrombocythemia	Enrichment	JAK2	1.34
522	Common variable immunodeficiency	Enrichment	NFKB1	1.34
523	Strabismus	Enrichment	CACNA1A, GNB1	1.30
524	Cardiomyopathy, familial hypertrophic, 4	Enrichment	BRAF	1.30
525	Coronary heart disease 5	Enrichment	IKBKG	1.30
526	Adult hepatocellular carcinoma	Enrichment	PIK3CA	1.30
527	Type 1 diabetes mellitus	Enrichment	INS	1.28
528	Amelogenesis imperfecta, type iiia	Enrichment	ITGB6	1.28
529	Migraine, familial hemiplegic, 1	Enrichment	CACNA1A	1.28
530	Spinocerebellar ataxia 6	Enrichment	CACNA1A	1.28
531	Developmental and epileptic encephalopathy 2	Enrichment	CACNA1A	1.28
532	Epidermolysis bullosa simplex 5c, with pyloric atresia	Enrichment	ITGB4	1.28
533	Pilomatrixoma	Enrichment	CTNNB1	1.28
534	Retinitis pigmentosa 26	Enrichment	ITGA4	1.28
535	Developmental and epileptic encephalopathy 42	Enrichment	CACNA1A	1.28
536	Alazami syndrome	Enrichment	CTNNB1	1.28
537	Developmental and epileptic encephalopathy 52	Enrichment	CACNA1A	1.28
538	Episodic ataxia	Enrichment	CACNA1A	1.28
539	Familial or sporadic hemiplegic migraine	Enrichment	CACNA1A	1.28
540	Pseudomyogenic hemangioendothelioma	Enrichment	FOSB	1.28
541	Brachydactyly	Enrichment	GNAS	1.28
542	Congenital nervous system abnormality	Enrichment	CACNA1A, CTNNB1, GNAO1, GNB5	1.27
543	Nervous system disease	Enrichment	CACNA1A, CTNNB1, GNAO1, GNB5	1.27
544	Polymicrogyria	Enrichment	AKT3	1.25
545	Melanoma	Enrichment	BRAF	1.25
546	Leukemia, acute lymphoblastic 3	Enrichment	JAK2	1.23
547	Spastic paraplegia 4, autosomal dominant	Enrichment	GNAS	1.22
548	Multiple pterygium syndrome, lethal type	Enrichment	RYR1	1.22
549	Congenital muscular dystrophy	Enrichment	RYR1	1.22
550	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	RYR2	1.22
551	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	RYR2	1.22
552	Hypothyroidism	Enrichment	GNB1	1.22
553	Familial isolated dilated cardiomyopathy	Enrichment	PLN, RAF1	1.20
554	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.19
555	Episodic ataxia, type 2	Enrichment	CACNA1A	1.18
556	Epidermolysis bullosa simplex 1c, localized	Enrichment	ITGB4	1.18
557	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.18
558	Night blindness, congenital stationary, type 1c	Enrichment	GNAT1	1.18
559	Glanzmann thrombasthenia 2	Enrichment	ITGB3	1.18
560	Muscular dystrophy, limb-girdle, autosomal recessive 23	Enrichment	LAMA2	1.18
561	Aplasia cutis congenita	Enrichment	ITGB4	1.18
562	Dementia	Enrichment	MAPT	1.18
563	Arrhythmogenic right ventricular dysplasia, familial, 9	Enrichment	PLN	1.17
564	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	CACNA1C	1.17
565	Permanent neonatal diabetes mellitus	Enrichment	INS	1.16
566	Complex neurodevelopmental disorder	Enrichment	CACNA1C, GNB2, PPP2CA	1.15
567	Protein-deficiency anemia	Enrichment	NRAS	1.14
568	Familial colorectal cancer	Enrichment	PLA2G2A	1.13
569	Inflammatory bowel disease 1	Enrichment	PRKCQ	1.11
570	Developmental dysplasia of the hip 1	Enrichment	PSMC3	1.11
571	Melanoma, uveal	Enrichment	GNA11	1.11
572	Dystonia 11, myoclonic	Enrichment	DRD2	1.11
573	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.11
574	Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndrome	Enrichment	BDNF	1.11
575	Patent ductus arteriosus	Enrichment	PSMC3	1.11
576	Dystonia	Enrichment	GNAL, GNB1	1.10
577	Leukemia, acute lymphoblastic	Enrichment	GNB1	1.09
578	Myelodysplastic syndrome	Enrichment	GNB1	1.09
579	Renal cell carcinoma, nonpapillary	Enrichment	MTOR	1.08
580	Wilms tumor 1	Enrichment	BRAF	1.08
581	Rare genetic intellectual disability	Enrichment	MTOR	1.08
582	Aortic valve disease 1	Enrichment	SOS1	1.08
583	Acute promyelocytic leukemia	Enrichment	STAT5B	1.08
584	Stroke, ischemic	Enrichment	PRKCH	1.07
585	Hereditary breast ovarian cancer syndrome	Enrichment	EIF2B5, KRAS	1.06
586	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	RYR2	1.05
587	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	RYR2	1.05
588	Osteoporosis	Enrichment	SRC	1.05
589	46,xy partial gonadal dysgenesis	Enrichment	SOS1	1.05
590	Neuropathy, hereditary sensory and autonomic, type v	Enrichment	NGF	1.04
591	Semantic dementia	Enrichment	MAPT	1.04
592	Epidermolysis bullosa simplex	Enrichment	ITGB4	1.04
593	Moyamoya angiopathy	Enrichment	ABL1	1.04
594	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	ABL1	1.04
595	Melanoma, cutaneous malignant 1	Enrichment	BRAF	1.03
596	Glycogen storage disease	Enrichment	GYS1	1.03
597	Diabetes mellitus	Enrichment	INS	1.03
598	Clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly	Enrichment	RYR1	1.02
599	Clubfoot	Enrichment	RYR1	1.02
600	Gliosarcoma	Enrichment	NFKBIA	0.99
601	Renal hypodysplasia/aplasia 1	Enrichment	ITGA8	0.99
602	Exudative vitreoretinopathy	Enrichment	CTNNB1	0.99
603	Alternating hemiplegia of childhood	Enrichment	CACNA1A	0.99
604	Essential tremor	Enrichment	DRD3	0.99
605	Choreatic disease	Enrichment	GNAO1	0.99
606	Difference of sex development	Enrichment	CACNA1A	0.99
607	Diffuse large b-cell lymphoma	Enrichment	BRAF	0.98
608	Giant cell glioblastoma	Enrichment	NFKBIA	0.97
609	Premature menopause	Enrichment	EIF2B2	0.96
610	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	0.96
611	Congenital myopathy 4a, autosomal dominant	Enrichment	RYR1	0.96
612	Endometrial cancer	Enrichment	PIK3CA	0.94
613	Heart, malformation of	Enrichment	MAPK1	0.94
614	Congenital central hypoventilation syndrome	Enrichment	BDNF	0.94
615	Progressive non-fluent aphasia	Enrichment	MAPT	0.94
616	Behavioral variant of frontotemporal dementia	Enrichment	MAPT	0.94
617	Renal agenesis, bilateral	Enrichment	ITGA8	0.94
618	West syndrome	Enrichment	GNAO1, NTRK2	0.93
619	Hypertension, essential	Enrichment	GNB3	0.91
620	Cleft palate, isolated	Enrichment	GNB1	0.91
621	Sudden infant death syndrome	Enrichment	PLN	0.91
622	Malaria	Enrichment	IKBKG	0.91
623	Omenn syndrome	Enrichment	PSMB10	0.90
624	Achromatopsia	Enrichment	GNAT2	0.90
625	Beckwith-wiedemann syndrome	Enrichment	RYR1	0.88
626	Neuromuscular disease	Enrichment	RYR1	0.88
627	Pancreatic cancer	Enrichment	KRAS	0.87
628	Thrombocytopenia	Enrichment	ITGA2B, ITGB3	0.87
629	Migraine with or without aura 1	Enrichment	CACNA1A	0.86
630	Frontotemporal dementia 1	Enrichment	MAPT	0.86
631	Movement disease	Enrichment	GNAO1	0.86
632	Presynaptic congenital myasthenic syndromes	Enrichment	LAMA5	0.86
633	Hydrops fetalis, nonimmune	Enrichment	HRAS	0.86
634	Prostate cancer	Enrichment	PIK3CA	0.81
635	Neural tube defects	Enrichment	ITGB1	0.79
636	Alzheimer's disease	Enrichment	MAPT	0.79
637	Amelogenesis imperfecta	Enrichment	LAMB3	0.79
638	Maturity-onset diabetes of the young	Enrichment	INS	0.78
639	Scoliosis	Enrichment	RYR1	0.77
640	Medulloblastoma	Enrichment	CTNNB1	0.76
641	Cone-rod dystrophy 6	Enrichment	GNAT2	0.76
642	Heart disease	Enrichment	ABL1	0.76
643	Isolated macular dystrophy	Enrichment	ITGA4	0.76
644	Undetermined early-onset epileptic encephalopathy	Enrichment	CACNA1A, NTRK2	0.76
645	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.76
646	Severe combined immunodeficiency	Enrichment	IKBKB	0.76
647	Brugada syndrome	Enrichment	CACNA1C	0.74
648	Kidney disease	Enrichment	LAMB2	0.74
649	Brittle bone disorder	Enrichment	EIF2B2	0.73
650	Non-syndromic x-linked intellectual disability	Enrichment	RPS6KA3	0.73
651	Parkinson disease, late-onset	Enrichment	EIF4G1	0.71
652	Creatine phosphokinase, elevated serum	Enrichment	LAMA2	0.71
653	Isolated elevated serum creatine phosphokinase levels	Enrichment	LAMA2	0.71
654	Alzheimer disease, familial, 1	Enrichment	MAPT	0.69
655	Polycystic liver disease	Enrichment	CTNNB1	0.69
656	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	0.69
657	Long qt syndrome 1	Enrichment	CACNA1C	0.68
658	Patent foramen ovale	Enrichment	PSMC3	0.67
659	Early infantile developmental and epileptic encephalopathy	Enrichment	GNAO1	0.67
660	Hepatoblastoma	Enrichment	CTNNB1	0.61
661	Fetal akinesia deformation sequence 1	Enrichment	RYR1	0.60
662	Autosomal dominant non-syndromic intellectual disability	Enrichment	YWHAZ	0.60
663	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ABL1	0.57
664	Myopathy	Enrichment	RYR1	0.57
665	Cone dystrophy	Enrichment	GNAT2	0.56
666	Autoinflammatory disease	Enrichment	PSMB8	0.56
667	Distal arthrogryposis	Enrichment	RYR1	0.55
668	Hypertrophic cardiomyopathy	Enrichment	PLN	0.55
669	Developmental and epileptic encephalopathy 1	Enrichment	GNAO1	0.54
670	Primary ovarian insufficiency	Enrichment	IGF2R	0.54
671	Auditory neuropathy	Enrichment	CACNA1A	0.53
672	Severe covid-19	Enrichment	ITGAV	0.49
673	Peripheral nervous system disease	Enrichment	NGF	0.45
674	Neuropathy	Enrichment	NGF	0.45
675	Genetic steroid-resistant nephrotic syndrome	Enrichment	LAMA5	0.43
676	Eye disease	Enrichment	GNAT2	0.42
677	Developmental and epileptic encephalopathy	Enrichment	GNAO1	0.41
678	Systemic lupus erythematosus	Enrichment	ITGAM	0.39
679	Charcot-marie-tooth disease	Enrichment	LAMA2	0.37
680	Primary ciliary dyskinesia	Enrichment	PRKAR1B	0.35
681	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	ADCY1	0.30
682	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	MAPT	0.26
683	Hereditary retinal dystrophy	Enrichment	GNAT1, GNAT2, ITGA4, LAMA1	0.26
684	Fundus dystrophy	Enrichment	GNAT1, GNAT2, ITGA4, LAMA1	0.26
685	Schizophrenia	Enrichment	DRD3	0.26
686	Cone-rod dystrophy 2	Enrichment	ITGA4	0.22
687	Inherited cancer-predisposing syndrome	Enrichment	PRKAR1A	0.19
688	Retinitis pigmentosa	Enrichment	GNAT1	0.02

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Beta-Adrenergic Signaling

Pathway Network for Beta-Adrenergic Signaling

Pathway network for the Beta-Adrenergic Signaling SuperPath

Member Pathways for Beta-Adrenergic Signaling

Pathways in the Beta-Adrenergic Signaling SuperPath

Gene overlap in member pathways for Beta-Adrenergic Signaling SuperPath

Associated Genes for Beta-Adrenergic Signaling

Associated Disorders for Beta-Adrenergic Signaling

Disorders associated with Beta-Adrenergic Signaling SuperPath

STRING Interaction Network for Beta-Adrenergic Signaling

Sources for Beta-Adrenergic Signaling