Beta2 integrin cell surface interactions

No Pathway Network information available for Beta2 integrin cell surface interactions

Pathways in the Beta2 integrin cell surface interactions SuperPath

#	Name	Source	Genes
1	Beta2 integrin cell surface interactions	PubChem	C3 CCN1 CD40LG F10 F11R FCGR2A FGA FGB FGG GP1BA ICAM1 ICAM2 ICAM3 ICAM4 ITGAD ITGAL ITGAM ITGAX ITGB2 JAM3 KNG1 PLAT PLAU PLAUR PROC SPON2 TGFBI THY1 VCAM1 (see all 29) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	THY1	Thy-1 Cell Surface Antigen	Protein Coding	1
2	CCN1	Cellular Communication Network Factor 1	Protein Coding	1
3	ICAM4	Intercellular Adhesion Molecule 4 (Landsteiner-Wiener Blood Group)	Protein Coding	1
4	SPON2	Spondin 2	Protein Coding	1
5	ICAM1	Intercellular Adhesion Molecule 1	Protein Coding	1
6	TGFBI	Transforming Growth Factor Beta Induced	Protein Coding	1
7	ICAM3	Intercellular Adhesion Molecule 3	Protein Coding	1
8	ICAM2	Intercellular Adhesion Molecule 2	Protein Coding	1
9	FCGR2A	Fc Gamma Receptor IIa	Protein Coding	1
10	CD40LG	CD40 Ligand	Protein Coding	1
11	C3	Complement C3	Protein Coding	1
12	PLAUR	Plasminogen Activator, Urokinase Receptor	Protein Coding	1
13	PLAT	Plasminogen Activator, Tissue Type	Protein Coding	1
14	PLAU	Plasminogen Activator, Urokinase	Protein Coding	1
15	PROC	Protein C, Inactivator Of Coagulation Factors Va And VIIIa	Protein Coding	1
16	KNG1	Kininogen 1	Protein Coding	1
17	GP1BA	Glycoprotein Ib Platelet Subunit Alpha	Protein Coding	1
18	FGA	Fibrinogen Alpha Chain	Protein Coding	1
19	FGB	Fibrinogen Beta Chain	Protein Coding	1
20	ITGAX	Integrin Subunit Alpha X	Protein Coding	1
21	ITGAD	Integrin Subunit Alpha D	Protein Coding	1
22	FGG	Fibrinogen Gamma Chain	Protein Coding	1
23	JAM3	Junctional Adhesion Molecule 3	Protein Coding	1
24	VCAM1	Vascular Cell Adhesion Molecule 1	Protein Coding	1
25	ITGAL	Integrin Subunit Alpha L	Protein Coding	1
26	ITGAM	Integrin Subunit Alpha M	Protein Coding	1
27	ITGB2	Integrin Subunit Beta 2	Protein Coding	1
28	F11R	F11 Receptor	Protein Coding	1
29	F10	Coagulation Factor X	Protein Coding	1

Disorders associated with Beta2 integrin cell surface interactions SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Dysfibrinogenemia, congenital	Enrichment	FGA, FGB, FGG	8.06
2	Familial dysfibrinogenemia	Enrichment	FGA, FGB, FGG	8.06
3	Familial hypofibrinogenemia	Enrichment	FGA, FGB, FGG	8.06
4	Afibrinogenemia, congenital	Enrichment	FGA, FGB, FGG	7.45
5	Thrombocytopenia	Enrichment	F10, FGG, GP1BA	3.85
6	Malaria	Enrichment	FCGR2A, ICAM1	2.96
7	Blood group system, landsteiner-wiener	Enrichment	ICAM4	2.67
8	Bernard-soulier syndrome, type a2, autosomal dominant	Enrichment	GP1BA	2.67
9	Corneal dystrophy, epithelial basement membrane	Enrichment	TGFBI	2.67
10	Corneal dystrophy, groenouw type i	Enrichment	TGFBI	2.67
11	Thrombophilia due to protein c deficiency, autosomal dominant	Enrichment	PROC	2.67
12	High molecular weight kininogen deficiency	Enrichment	KNG1	2.67
13	Corneal dystrophy, avellino type	Enrichment	TGFBI	2.67
14	Systemic lupus erythematosus 6	Enrichment	ITGAM	2.67
15	Nonarteritic anterior ischemic optic neuropathy	Enrichment	GP1BA	2.67
16	Von willebrand disease, platelet-type	Enrichment	GP1BA	2.67
17	Hemolytic uremic syndrome, atypical 5	Enrichment	C3	2.67
18	Corneal dystrophy, lattice type i	Enrichment	TGFBI	2.67
19	Corneal dystrophy, thiel-behnke type	Enrichment	TGFBI	2.67
20	Immunodeficiency with hyper-igm, type 1	Enrichment	CD40LG	2.67
21	Angioedema, hereditary, 6	Enrichment	KNG1	2.67
22	Epithelial-stromal tgfbi dystrophy	Enrichment	TGFBI	2.67
23	Thrombophilia due to protein c deficiency, autosomal recessive	Enrichment	PROC	2.67
24	Corneal dystrophy, lattice type iiia	Enrichment	TGFBI	2.67
25	Corneal dystrophy, reis-bucklers type	Enrichment	TGFBI	2.67
26	Granular corneal dystrophy	Enrichment	TGFBI	2.67
27	Hemorrhagic destruction of the brain, subependymal calcification, and cataracts	Enrichment	JAM3	2.67
28	Macular degeneration, age-related, 9	Enrichment	C3	2.67
29	Complement component 3 deficiency, autosomal recessive	Enrichment	C3	2.67
30	Complement component 3 deficiency	Enrichment	C3	2.67
31	Epithelial basement membrane dystrophy	Enrichment	TGFBI	2.67
32	Bernard-soulier syndrome type a2	Enrichment	GP1BA	2.67
33	Congenital fibrinogen deficiency	Enrichment	FGG	2.67
34	Membranoproliferative glomerulonephritis	Enrichment	C3	2.67
35	Primary membranoproliferative glomerulonephritis	Enrichment	C3	2.67
36	Severe hereditary thrombophilia due to congenital protein c deficiency	Enrichment	PROC	2.67
37	Protein c deficiency	Enrichment	PROC	2.67
38	Cd40 ligand deficiency	Enrichment	CD40LG	2.67
39	Lethal hydranencephaly-diaphragmatic hernia syndrome	Enrichment	PLAT	2.67
40	Porencephaly-microcephaly-bilateral congenital cataract syndrome	Enrichment	JAM3	2.67
41	Systemic lupus erythematosus	Enrichment	FCGR2A, ITGAM	2.51
42	Leukocyte adhesion deficiency, type i	Enrichment	ITGB2	2.37
43	Quebec platelet disorder	Enrichment	PLAU	2.37
44	Leukocyte adhesion deficiency, type iii	Enrichment	ITGB2	2.37
45	Factor x deficiency	Enrichment	F10	2.19
46	Genetic atypical hemolytic-uremic syndrome	Enrichment	C3	2.19
47	Congenital factor x deficiency	Enrichment	F10	2.19
48	Corneal dystrophy	Enrichment	TGFBI	2.07
49	Cerebral malaria	Enrichment	ICAM1	2.07
50	Hereditary angioedema with normal c1inh not related to f12 or plg variant	Enrichment	KNG1	2.07
51	Alzheimer disease 2	Enrichment	PLAU	1.97
52	Amyloidosis, hereditary systemic 2	Enrichment	FGA	1.97
53	Bernard-soulier syndrome	Enrichment	GP1BA	1.97
54	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	GP1BA	1.89
55	Atypical hemolytic uremic syndrome with complement gene abnormality	Enrichment	C3	1.89
56	Thrombophilia due to thrombin defect	Enrichment	FGA	1.83
57	Common variable immunodeficiency	Enrichment	CD40LG	1.83
58	Spastic paraplegia 4, autosomal dominant	Enrichment	FGG	1.77
59	Autosomal dominant macrothrombocytopenia	Enrichment	GP1BA	1.67
60	Atypical hemolytic-uremic syndrome	Enrichment	C3	1.50
61	Alzheimer disease, familial, 1	Enrichment	PLAU	1.45
62	Cystic fibrosis	Enrichment	FCGR2A	1.18
63	Cerebral palsy	Enrichment	PROC	1.10

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Beta2 integrin cell surface interactions

Pathway Network for Beta2 integrin cell surface interactions

Member Pathways for Beta2 integrin cell surface interactions

Pathways in the Beta2 integrin cell surface interactions SuperPath

Associated Genes for Beta2 integrin cell surface interactions

Associated Disorders for Beta2 integrin cell surface interactions

Disorders associated with Beta2 integrin cell surface interactions SuperPath

STRING Interaction Network for Beta2 integrin cell surface interactions

Sources for Beta2 integrin cell surface interactions