Beta5 beta6 beta7 and beta8 integrin cell surface interactions

No Pathway Network information available for Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Pathways in the Beta5 beta6 beta7 and beta8 integrin cell surface interactions SuperPath

#	Name	Source	Genes
1	Beta5 beta6 beta7 and beta8 integrin cell surface interactions	PubChem	CCN1 EDIL3 FBN1 FN1 ITGA4 ITGAV ITGB5 ITGB6 ITGB7 ITGB8 MADCAM1 PLAU PLAUR SDC1 TGFBR1 VCAM1 VTN (see all 17) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CCN1	Cellular Communication Network Factor 1	Protein Coding	1
2	MADCAM1	Mucosal Vascular Addressin Cell Adhesion Molecule 1	Protein Coding	1
3	EDIL3	EGF Like And Discoidin Domains 3	Protein Coding	1
4	TGFBR1	Transforming Growth Factor Beta Receptor 1	Protein Coding	1
5	SDC1	Syndecan 1	Protein Coding	1
6	PLAUR	Plasminogen Activator, Urokinase Receptor	Protein Coding	1
7	PLAU	Plasminogen Activator, Urokinase	Protein Coding	1
8	FBN1	Fibrillin 1	Protein Coding	1
9	VTN	Vitronectin	Protein Coding	1
10	ITGB7	Integrin Subunit Beta 7	Protein Coding	1
11	VCAM1	Vascular Cell Adhesion Molecule 1	Protein Coding	1
12	ITGB6	Integrin Subunit Beta 6	Protein Coding	1
13	ITGA4	Integrin Subunit Alpha 4	Protein Coding	1
14	ITGB8	Integrin Subunit Beta 8	Protein Coding	1
15	FN1	Fibronectin 1	Protein Coding	1
16	ITGAV	Integrin Subunit Alpha V	Protein Coding	1
17	ITGB5	Integrin Subunit Beta 5	Protein Coding	1

Disorders associated with Beta5 beta6 beta7 and beta8 integrin cell surface interactions SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Aortic aneurysm	Enrichment	FBN1, TGFBR1	5.05
2	Loeys-dietz syndrome	Enrichment	FBN1, TGFBR1	4.28
3	Marfan syndrome	Enrichment	FBN1, TGFBR1	4.18
4	Pectus excavatum	Enrichment	FBN1, TGFBR1	4.09
5	Ectopia lentis 1, isolated, autosomal dominant	Enrichment	FBN1	2.90
6	Multiple self-healing squamous epithelioma	Enrichment	TGFBR1	2.90
7	Weill-marchesani syndrome 2	Enrichment	FBN1	2.90
8	Geleophysic dysplasia 2	Enrichment	FBN1	2.90
9	Protrusio acetabuli	Enrichment	FBN1	2.90
10	Lymphoplasmacytic lymphoma	Enrichment	FBN1	2.90
11	Amelogenesis imperfecta, type ih	Enrichment	ITGB6	2.90
12	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	2.90
13	Neonatal marfan syndrome	Enrichment	FBN1	2.90
14	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	FBN1, TGFBR1	2.87
15	Acromicric dysplasia	Enrichment	FBN1	2.60
16	Spondyloepimetaphyseal dysplasia, strudwick type	Enrichment	FN1	2.60
17	Spondylometaphyseal dysplasia, corner fracture type	Enrichment	FN1	2.60
18	Stiff skin syndrome	Enrichment	FBN1	2.60
19	Quebec platelet disorder	Enrichment	PLAU	2.60
20	Loeys-dietz syndrome 2	Enrichment	TGFBR1	2.60
21	Beaulieu-boycott-innes syndrome	Enrichment	FBN1	2.60
22	Aortic dissection	Enrichment	FBN1	2.60
23	Marfanoid-progeroid-lipodystrophy syndrome	Enrichment	FBN1	2.60
24	Lens subluxation	Enrichment	FBN1	2.60
25	Contractural arachnodactyly, congenital	Enrichment	FBN1	2.43
26	Achondroplasia	Enrichment	FBN1	2.43
27	Mccune-albright syndrome	Enrichment	FBN1	2.43
28	Glomerulopathy with fibronectin deposits 2	Enrichment	FN1	2.43
29	Weill-marchesani syndrome 1	Enrichment	FBN1	2.43
30	Isolated ectopia lentis	Enrichment	FBN1	2.43
31	Loeys-dietz syndrome 1	Enrichment	TGFBR1	2.43
32	Geleophysic dysplasia	Enrichment	FBN1	2.43
33	Alopecia - intellectual disability syndrome	Enrichment	ITGB6	2.43
34	Amelogenesis imperfecta, type iiia	Enrichment	ITGB6	2.30
35	Retinitis pigmentosa 26	Enrichment	ITGA4	2.30
36	Weill-marchesani syndrome	Enrichment	FBN1	2.30
37	Mitral valve insufficiency	Enrichment	FBN1	2.30
38	Polycystic liver disease 1 with or without kidney cysts	Enrichment	FBN1	2.20
39	Alzheimer disease 2	Enrichment	PLAU	2.20
40	Arthrogryposis, renal dysfunction, and cholestasis 1	Enrichment	FBN1	2.20
41	Goldberg-shprintzen syndrome	Enrichment	FBN1	2.20
42	Polycystic liver disease 1	Enrichment	FBN1	2.20
43	Inguinal hernia	Enrichment	FBN1	2.13
44	Classic ehlers-danlos syndrome	Enrichment	TGFBR1	2.13
45	Brugada syndrome 1	Enrichment	FBN1	2.06
46	Orthostatic intolerance	Enrichment	FBN1	2.00
47	Familial thoracic aortic aneurysm and dissection	Enrichment	FBN1	1.95
48	Amelogenesis imperfecta, type ie	Enrichment	ITGB6	1.90
49	Stroke, ischemic	Enrichment	FBN1	1.90
50	Melanoma	Enrichment	FBN1	1.90
51	Diaphragmatic hernia, congenital	Enrichment	FBN1	1.79
52	Aortic aneurysm, familial thoracic 1	Enrichment	FBN1	1.76
53	Isolated macular dystrophy	Enrichment	ITGA4	1.76
54	Myopia	Enrichment	FBN1	1.73
55	Perrault syndrome 1	Enrichment	FBN1	1.70
56	Alzheimer disease, familial, 1	Enrichment	PLAU	1.68
57	Scoliosis	Enrichment	FBN1	1.53
58	Severe covid-19	Enrichment	ITGAV	1.45
59	Connective tissue disease	Enrichment	FBN1	1.40
60	Myopathy	Enrichment	FBN1	1.31
61	Nephrotic syndrome	Enrichment	FN1	1.28
62	Cone-rod dystrophy 2	Enrichment	ITGA4	1.09
63	Dilated cardiomyopathy	Enrichment	FBN1	1.02
64	Hereditary retinal dystrophy	Enrichment	ITGA4	0.51
65	Fundus dystrophy	Enrichment	ITGA4	0.51

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Pathway Network for Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Member Pathways for Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Pathways in the Beta5 beta6 beta7 and beta8 integrin cell surface interactions SuperPath

Associated Genes for Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Associated Disorders for Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Disorders associated with Beta5 beta6 beta7 and beta8 integrin cell surface interactions SuperPath

STRING Interaction Network for Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Sources for Beta5 beta6 beta7 and beta8 integrin cell surface interactions