Biofilm formation

Pathway network for the Biofilm formation SuperPath

Sources:

Reactome
GeneGo (Thomson Reuters)
PubChem

Pathways in the Biofilm formation SuperPath

#	Name	Source	Genes
1	Biofilm formation	Reactome	COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 EPCAM FN1 LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMC1 LAMC2 LAMC3 UPK1A (see all 23) (see less)
2	Cell adhesion Endothelial cell contacts by non-junctional mechanisms	GeneGo (Thomson Reuters)	ACTB ACTG1 ACTN1 ACTN2 ACTN3 ACTN4 CDH2 COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 CTNNA1 CTNNA2 CTNNA3 CTNNB1 CTNND1 ESAM FN1 ITGA1 ITGA2 ITGA3 ITGA5 ITGA6 ITGAV ITGB1 ITGB3 ITGB4 ITGB5 JUP LAMA1 LAMA4 LAMB1 LAMC1 MAGI1 PECAM1 VTN (see all 40) (see less)
3	Laminin interactions	Reactome	COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL7A1 HSPG2 ITGA1 ITGA2 ITGA3 ITGA6 ITGA7 ITGAV ITGB1 ITGB4 LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMC1 LAMC2 LAMC3 NID1 NID2 (see all 30) (see less)
4	Infection with Enterobacteria	Reactome	COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 EPCAM FN1 HBA1 HBA2 HBB LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMC1 LAMC2 LAMC3 UPK1A (see all 26) (see less)
5	Attachment of bacteria to epithelial cells	Reactome	COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 EPCAM FN1 LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMC1 LAMC2 LAMC3 UPK1A (see all 23) (see less)
6	Fibronectin matrix formation	Reactome	CEACAM1 CEACAM6 CEACAM8 COL1A1 COL1A2 COL2A1 COL3A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COL5A1 COL5A2 COL5A3 COL7A1 FN1 ITGA5 ITGB1 (see all 20) (see less)
7	Alpha6 beta4 integrin-ligand interactions	PubChem	ITGA6 ITGB4 LAMA1 LAMA2 LAMA3 LAMA5 LAMB1 LAMB2 LAMB3 LAMC1 LAMC2 (see all 11) (see less)

Gene overlap in member pathways for Biofilm formation SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	COL4A1	Collagen Type IV Alpha 1 Chain	Protein Coding	6
2	COL4A2	Collagen Type IV Alpha 2 Chain	Protein Coding	6
3	COL4A3	Collagen Type IV Alpha 3 Chain	Protein Coding	6
4	COL4A4	Collagen Type IV Alpha 4 Chain	Protein Coding	6
5	COL4A5	Collagen Type IV Alpha 5 Chain	Protein Coding	6
6	COL4A6	Collagen Type IV Alpha 6 Chain	Protein Coding	6
7	LAMA1	Laminin Subunit Alpha 1	Protein Coding	6
8	LAMB1	Laminin Subunit Beta 1	Protein Coding	6
9	LAMC1	Laminin Subunit Gamma 1	Protein Coding	6
10	FN1	Fibronectin 1	Protein Coding	5
11	LAMA2	Laminin Subunit Alpha 2	Protein Coding	5
12	LAMA3	Laminin Subunit Alpha 3	Protein Coding	5
13	LAMA4	Laminin Subunit Alpha 4	Protein Coding	5
14	LAMA5	Laminin Subunit Alpha 5	Protein Coding	5
15	LAMB2	Laminin Subunit Beta 2	Protein Coding	5
16	LAMB3	Laminin Subunit Beta 3	Protein Coding	5
17	LAMC2	Laminin Subunit Gamma 2	Protein Coding	5
18	LAMC3	Laminin Subunit Gamma 3	Protein Coding	4
19	COL5A1	Collagen Type V Alpha 1 Chain	Protein Coding	4
20	COL5A2	Collagen Type V Alpha 2 Chain	Protein Coding	4
21	COL5A3	Collagen Type V Alpha 3 Chain	Protein Coding	4
22	UPK1A	Uroplakin 1A	Protein Coding	3
23	EPCAM	Epithelial Cell Adhesion Molecule	Protein Coding	3
24	ITGA6	Integrin Subunit Alpha 6	Protein Coding	3
25	ITGB1	Integrin Subunit Beta 1	Protein Coding	3
26	ITGB4	Integrin Subunit Beta 4	Protein Coding	3
27	COL1A1	Collagen Type I Alpha 1 Chain	Protein Coding	2
28	COL1A2	Collagen Type I Alpha 2 Chain	Protein Coding	2
29	ITGA1	Integrin Subunit Alpha 1	Protein Coding	2
30	ITGA2	Integrin Subunit Alpha 2	Protein Coding	2
31	ITGA3	Integrin Subunit Alpha 3	Protein Coding	2
32	ITGA5	Integrin Subunit Alpha 5	Protein Coding	2
33	ITGAV	Integrin Subunit Alpha V	Protein Coding	2
34	COL7A1	Collagen Type VII Alpha 1 Chain	Protein Coding	2
35	ACTB	Actin Beta	Protein Coding	1
36	ACTG1	Actin Gamma 1	Protein Coding	1
37	ACTN4	Actinin Alpha 4	Protein Coding	1
38	ACTN1	Actinin Alpha 1	Protein Coding	1
39	ACTN2	Actinin Alpha 2	Protein Coding	1
40	ACTN3	Actinin Alpha 3	Protein Coding	1
41	CDH2	Cadherin 2	Protein Coding	1
42	CTNNA1	Catenin Alpha 1	Protein Coding	1
43	CTNNA2	Catenin Alpha 2	Protein Coding	1
44	CTNNB1	Catenin Beta 1	Protein Coding	1
45	CTNND1	Catenin Delta 1	Protein Coding	1
46	ITGB3	Integrin Subunit Beta 3	Protein Coding	1
47	ITGB5	Integrin Subunit Beta 5	Protein Coding	1
48	JUP	Junction Plakoglobin	Protein Coding	1
49	PECAM1	Platelet And Endothelial Cell Adhesion Molecule 1	Protein Coding	1
50	VTN	Vitronectin	Protein Coding	1
51	MAGI1	Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 1	Protein Coding	1
52	CTNNA3	Catenin Alpha 3	Protein Coding	1
53	ESAM	Endothelial Cell Adhesion Molecule	Protein Coding	1
54	NID2	Nidogen 2	Protein Coding	1
55	HSPG2	Heparan Sulfate Proteoglycan 2	Protein Coding	1
56	ITGA7	Integrin Subunit Alpha 7	Protein Coding	1
57	NID1	Nidogen 1	Protein Coding	1
58	COL18A1	Collagen Type XVIII Alpha 1 Chain	Protein Coding	1
59	HBA1	Hemoglobin Subunit Alpha 1	Protein Coding	1
60	HBA2	Hemoglobin Subunit Alpha 2	Protein Coding	1
61	HBB	Hemoglobin Subunit Beta	Protein Coding	1
62	CEACAM8	CEA Cell Adhesion Molecule 8	Protein Coding	1
63	COL2A1	Collagen Type II Alpha 1 Chain	Protein Coding	1
64	COL3A1	Collagen Type III Alpha 1 Chain	Protein Coding	1
65	CEACAM6	CEA Cell Adhesion Molecule 6	Protein Coding	1
66	CEACAM1	CEA Cell Adhesion Molecule 1	Protein Coding	1

Disorders associated with Biofilm formation SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Bacterial infectious disease	Direct
2	Junctional epidermolysis bullosa	Enrichment	ITGA6, ITGB4, LAMA3, LAMB3, LAMC2	10.68
3	Epidermolysis bullosa, junctional 1a, intermediate	Enrichment	ITGB4, LAMA3, LAMB3, LAMC2	10.36
4	Junctional epidermolysis bullosa non-herlitz type	Enrichment	ITGB4, LAMA3, LAMB3, LAMC2	10.36
5	Ehlers-danlos syndrome	Enrichment	COL1A1, COL1A2, COL3A1, COL5A1, COL5A2	10.17
6	Ehlers-danlos syndrome, classic type, 1	Enrichment	COL1A1, COL1A2, COL5A1, COL5A2	10.05
7	Classic ehlers-danlos syndrome	Enrichment	COL1A1, COL1A2, COL5A1, COL5A2	10.05
8	Nephrotic syndrome	Enrichment	COL4A3, COL4A4, COL4A5, ITGA3, LAMA5, LAMB2	9.39
9	Digenic alport syndrome	Enrichment	COL4A3, COL4A4, COL4A5	8.56
10	Epidermolysis bullosa, junctional 1b, severe	Enrichment	LAMA3, LAMB3, LAMC2	8.10
11	Kidney disease	Enrichment	COL4A3, COL4A4, COL4A5, LAMB2	7.58
12	Alport syndrome 3a, autosomal dominant	Enrichment	COL4A3, COL4A4, COL4A5	7.56
13	Autosomal dominant alport syndrome	Enrichment	COL4A3, COL4A4, COL4A5	7.56
14	Alport syndrome	Enrichment	COL4A3, COL4A4, COL4A5	7.56
15	Keratoconus	Enrichment	COL1A1, COL4A1, COL5A2	7.26
16	Epidermolysis bullosa	Enrichment	COL7A1, ITGA6, LAMB3	7.01
17	Skin disease	Enrichment	COL7A1, ITGB4, LAMB3, LAMC2	6.86
18	Multiple sclerosis	Enrichment	ITGB4, LAMA5, LAMB1	6.84
19	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	COL1A1, COL3A1, COL5A1, COL5A2	6.35
20	Spondyloepimetaphyseal dysplasia, strudwick type	Enrichment	COL2A1, FN1	5.69
21	Spondylometaphyseal dysplasia, corner fracture type	Enrichment	COL2A1, FN1	5.69
22	Ehlers-danlos syndrome, arthrochalasia type, 2	Enrichment	COL1A1, COL1A2	5.69
23	Ehlers-danlos/osteogenesis imperfecta syndrome	Enrichment	COL1A1, COL1A2	5.69
24	X-linked diffuse leiomyomatosis-alport syndrome	Enrichment	COL4A5, COL4A6	5.69
25	Hematuria, benign familial, 1	Enrichment	COL4A3, COL4A4	5.21
26	Ehlers-danlos syndrome, classic type, 2	Enrichment	COL5A1, COL5A2	5.21
27	High bone mass osteogenesis imperfecta	Enrichment	COL1A1, COL1A2	5.21
28	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	CDH2, CTNNA3, JUP	5.07
29	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	5.07
30	Epidermolysis bullosa, junctional 5b, with pyloric atresia	Enrichment	ITGA6, ITGB4	5.05
31	Ehlers-danlos syndrome, arthrochalasia type, 1	Enrichment	COL1A1, COL1A2	4.91
32	Brain small vessel disease 1 with or without ocular anomalies	Enrichment	COL4A1, COL4A2	4.91
33	Alport syndrome 2, autosomal recessive	Enrichment	COL4A3, COL4A4	4.91
34	Autosomal recessive alport syndrome	Enrichment	COL4A3, COL4A4	4.91
35	Osteogenesis imperfecta with normal sclerae, dominant form	Enrichment	COL1A1, COL1A2	4.91
36	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	ACTN2, CTNNA3, JUP	4.89
37	Familial porencephaly	Enrichment	COL4A1, COL4A2	4.69
38	Osteogenesis imperfecta, type i	Enrichment	COL1A1, COL1A2	4.51
39	Hemorrhage, intracerebral	Enrichment	COL4A1, COL4A2	4.51
40	Osteogenesis imperfecta, type ii	Enrichment	COL1A1, COL1A2	4.36
41	Primary bone dysplasia	Enrichment	COL1A1, COL1A2	4.03
42	Osteochondrodysplasia	Enrichment	COL1A1, COL1A2	3.95
43	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGA2, ITGB3	3.90
44	Osteogenesis imperfecta, type iv	Enrichment	COL1A1, COL1A2	3.80
45	Chronic kidney disease	Enrichment	COL4A4, COL4A5	3.80
46	Osteoporosis	Enrichment	COL1A1, COL1A2	3.73
47	Osteogenesis imperfecta, type iii	Enrichment	COL1A1, COL1A2	3.67
48	Myopia	Enrichment	COL2A1, COL4A4	3.67
49	Hypertension	Enrichment	COL4A4, COL4A5	3.61
50	Autosomal dominant macrothrombocytopenia	Enrichment	ACTN1, ITGB3	3.42
51	Focal segmental glomerulosclerosis	Enrichment	COL4A4, COL4A5	3.41
52	Microcephaly	Enrichment	ACTB, ACTG1, COL4A1, CTNNB1	3.34
53	Brittle bone disorder	Enrichment	COL1A1, COL1A2	3.29
54	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	CTNNA3, JUP	3.26
55	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	CTNNA3, JUP	3.26
56	Lissencephaly 5	Enrichment	LAMB1	3.09
57	Nephrotic syndrome, type 26	Enrichment	LAMA5	3.09
58	Bent bone dysplasia syndrome 2	Enrichment	LAMA5	3.09
59	Lama5-related multisystemic syndrome	Enrichment	LAMA5	3.09
60	Laminin subunit alpha 2-related muscular dystrophy	Enrichment	LAMA2	3.09
61	Corpus callosum, agenesis of	Enrichment	CDH2, COL4A1	3.06
62	Isolated corpus callosum agenesis	Enrichment	CDH2, COL4A1	3.06
63	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CDH2, COL4A1	3.06
64	Connective tissue disease	Enrichment	COL2A1, COL5A1	3.00
65	Stickler syndrome, type i	Enrichment	COL2A1	2.83
66	Epidermolysis bullosa dystrophica, pretibial	Enrichment	COL7A1	2.83
67	Epidermolysis bullosa dystrophica, autosomal dominant	Enrichment	COL7A1	2.83
68	Epiphyseal dysplasia, multiple, with myopia and conductive deafness	Enrichment	COL2A1	2.83
69	Ehlers-danlos syndrome, cardiac valvular type	Enrichment	COL1A2	2.83
70	Epidermolysis bullosa dystrophica, autosomal recessive	Enrichment	COL7A1	2.83
71	Spondylometaphyseal dysplasia, algerian type	Enrichment	COL2A1	2.83
72	Alport syndrome 1, x-linked	Enrichment	COL4A5	2.83
73	Osteoarthritis with mild chondrodysplasia	Enrichment	COL2A1	2.83
74	Avascular necrosis of femoral head, primary, 1	Enrichment	COL2A1	2.83
75	Czech dysplasia	Enrichment	COL2A1	2.83
76	Nail disorder, nonsyndromic congenital, 8	Enrichment	COL7A1	2.83
77	Kniest dysplasia	Enrichment	COL2A1	2.83
78	Transient bullous dermolysis of the newborn	Enrichment	COL7A1	2.83
79	Platyspondylic lethal skeletal dysplasia, torrance type	Enrichment	COL2A1	2.83
80	Epidermolysis bullosa with congenital localized absence of skin and deformity of nails	Enrichment	COL7A1	2.83
81	Spondyloepiphyseal dysplasia, stanescu type	Enrichment	COL2A1	2.83
82	Acrogeria, gottron type	Enrichment	COL3A1	2.83
83	Achondrogenesis, type ii	Enrichment	COL2A1	2.83
84	Deafness, x-linked 6	Enrichment	COL4A6	2.83
85	Combined osteogenesis imperfecta and ehlers-danlos syndrome 2	Enrichment	COL1A2	2.83
86	Spondyloperipheral dysplasia	Enrichment	COL2A1	2.83
87	Porencephaly	Enrichment	COL4A1	2.83
88	Epidermolysis bullosa pruriginosa	Enrichment	COL7A1	2.83
89	Stickler syndrome, type i, nonsyndromic ocular	Enrichment	COL2A1	2.83
90	Thyroid gland disease	Enrichment	COL7A1	2.83
91	Vitreoretinopathy with phalangeal epiphyseal dysplasia	Enrichment	COL2A1	2.83
92	Recessive dystrophic epidermolysis bullosa-generalized other	Enrichment	COL7A1	2.83
93	Asphyxia neonatorum	Enrichment	COL1A1	2.83
94	Col4a1-related disorders	Enrichment	COL4A1	2.83
95	Autosomal dominant rhegmatogenous retinal detachment	Enrichment	COL2A1	2.83
96	Col4a1 or col4a2-related cerebral small vessel disease	Enrichment	COL4A1	2.83
97	Multiple epiphyseal dysplasia with myopia and deafness	Enrichment	COL2A1	2.83
98	Hypochondrogenesis	Enrichment	COL2A1	2.83
99	X-linked alport syndrome	Enrichment	COL4A5	2.83
100	Pneumothorax	Enrichment	COL5A1	2.83
101	Localized dystrophic epidermolysis bullosa, acral form	Enrichment	COL7A1	2.83
102	Dysspondyloenchondromatosis	Enrichment	COL2A1	2.83
103	Abdominal aortic aneurysm	Enrichment	COL3A1	2.83
104	Recessive dystrophic epidermolysis bullosa inversa	Enrichment	COL7A1	2.83
105	Type 2 collagen-related bone disorder	Enrichment	COL2A1	2.83
106	Generalized dominant dystrophic epidermolysis bullosa	Enrichment	COL7A1	2.83
107	Cerebral palsy	Enrichment	COL4A1, COL4A2	2.83
108	Amelogenesis imperfecta, type ia	Enrichment	LAMB3	2.79
109	Epidermolysis bullosa, junctional 2c, laryngoonychocutaneous	Enrichment	LAMA3	2.79
110	Myasthenic syndrome, congenital, 5	Enrichment	LAMB2	2.79
111	Lissencephaly 1	Enrichment	LAMB1	2.79
112	Pierson syndrome	Enrichment	LAMB2	2.79
113	Epidermolysis bullosa, junctional 3b, severe	Enrichment	LAMC2	2.79
114	Epidermolysis bullosa, junctional 3a, intermediate	Enrichment	LAMC2	2.79
115	Epidermolysis bullosa, junctional 2a, intermediate	Enrichment	LAMA3	2.79
116	Epidermolysis bullosa, junctional 5a, intermediate	Enrichment	ITGB4	2.79
117	Nephrotic syndrome, type 5, with or without ocular abnormalities	Enrichment	LAMB2	2.79
118	Epidermolysis bullosa, junctional 2b, severe	Enrichment	LAMA3	2.79
119	Localized junctional epidermolysis bullosa, non-herlitz type	Enrichment	ITGB4	2.79
120	Cardiomyopathy, dilated, 1jj	Enrichment	LAMA4	2.66
121	Cortical malformations, occipital	Enrichment	LAMC3	2.66
122	Occipital pachygyria and polymicrogyria	Enrichment	LAMC3	2.66
123	Fetomaternal alloimmune thrombocytopenia 3	Enrichment	ITGA2	2.66
124	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	2.66
125	Muscular dystrophy, congenital merosin-deficient, 1a	Enrichment	LAMA2	2.61
126	Epidermolysis bullosa, junctional 6, with pyloric atresia	Enrichment	ITGA6	2.61
127	Poretti-boltshauser syndrome	Enrichment	LAMA1	2.61
128	Lama2-related muscular dystrophy	Enrichment	LAMA2	2.61
129	Genetic steroid-resistant nephrotic syndrome	Enrichment	COL4A3, LAMA5	2.60
130	Ehlers-danlos syndrome, vascular type	Enrichment	COL3A1	2.53
131	Epiphyseal dysplasia, multiple, 1	Enrichment	COL1A1	2.53
132	Ehlers-danlos syndrome, hypermobility type	Enrichment	COL3A1	2.53
133	Bruck syndrome 1	Enrichment	COL1A2	2.53
134	Otospondylomegaepiphyseal dysplasia, autosomal recessive	Enrichment	COL2A1	2.53
135	Dermatofibrosarcoma protuberans	Enrichment	COL1A1	2.53
136	Legg-calve-perthes disease	Enrichment	COL2A1	2.53
137	Specific language impairment 5	Enrichment	COL4A4	2.53
138	Otospondylomegaepiphyseal dysplasia, autosomal dominant	Enrichment	COL2A1	2.53
139	Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy, 1	Enrichment	COL4A2	2.53
140	Combined osteogenesis imperfecta and ehlers-danlos syndrome 1	Enrichment	COL1A1	2.53
141	Fibromuscular dysplasia, multifocal	Enrichment	COL5A1	2.53
142	Polymicrogyria with or without vascular-type ehlers-danlos syndrome	Enrichment	COL3A1	2.53
143	Aortic dissection	Enrichment	COL3A1	2.53
144	Recessive dystrophic epidermolysis bullosa	Enrichment	COL7A1	2.53
145	Glomerulonephritis	Enrichment	COL4A4	2.53
146	Stickler syndrome, type ii	Enrichment	COL1A1	2.53
147	Familial avascular necrosis of the femoral head	Enrichment	COL2A1	2.53
148	Dentinogenesis imperfecta	Enrichment	COL1A2	2.53
149	Epidermolysis bullosa dystrophica	Enrichment	COL7A1	2.53
150	Baraitser-winter syndrome 1	Enrichment	ACTB	2.53
151	Focal segmental glomerulosclerosis 1	Enrichment	ACTN4	2.53
152	Arrhythmogenic right ventricular dysplasia, familial, 12	Enrichment	JUP	2.53
153	Macular dystrophy, patterned, 2	Enrichment	CTNNA1	2.53
154	Cardiomyopathy, dilated, 1aa, with or without left ventricular noncompaction	Enrichment	ACTN2	2.53
155	Arrhythmogenic right ventricular dysplasia, familial, 13	Enrichment	CTNNA3	2.53
156	Naxos disease	Enrichment	JUP	2.53
157	Cortical dysplasia, complex, with other brain malformations 9	Enrichment	CTNNA2	2.53
158	Congenital myopathy 8	Enrichment	ACTN2	2.53
159	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	2.53
160	Agenesis of corpus callosum, cardiac, ocular, and genital syndrome	Enrichment	CDH2	2.53
161	Actn3 deficiency	Enrichment	ACTN3	2.53
162	Becker nevus syndrome	Enrichment	ACTB	2.53
163	Dystonia-deafness syndrome 1	Enrichment	ACTB	2.53
164	Arrhythmogenic right ventricular dysplasia, familial, 14	Enrichment	CDH2	2.53
165	Bleeding disorder, platelet-type, 15	Enrichment	ACTN1	2.53
166	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	2.53
167	Myopathy, distal, 6, adult-onset, autosomal dominant	Enrichment	ACTN2	2.53
168	Attention deficit-hyperactivity disorder 8	Enrichment	CDH2	2.53
169	Adenoid ameloblastoma	Enrichment	CTNNB1	2.53
170	Baraitser-winter syndrome	Enrichment	ACTB	2.53
171	Congenital smooth muscle hamartoma	Enrichment	ACTB	2.53
172	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	2.53
173	Microcystic stromal tumor	Enrichment	CTNNB1	2.53
174	Epidermolysis bullosa simplex 5c, with pyloric atresia	Enrichment	ITGB4	2.49
175	Bladder cancer	Enrichment	CTNNA3, CTNNB1	2.49
176	Epidermolysis bullosa simplex 1c, localized	Enrichment	ITGB4	2.39
177	Muscular dystrophy, limb-girdle, autosomal recessive 23	Enrichment	LAMA2	2.39
178	Aplasia cutis congenita	Enrichment	ITGB4	2.39
179	Mccune-albright syndrome	Enrichment	COL2A1	2.35
180	Retinal arteries, tortuosity of	Enrichment	COL4A1	2.35
181	Spondyloepiphyseal dysplasia congenita	Enrichment	COL2A1	2.35
182	Nail disorder, nonsyndromic congenital, 4	Enrichment	COL7A1	2.35
183	Telecanthus	Enrichment	COL5A2	2.35
184	Glomerulopathy with fibronectin deposits 2	Enrichment	FN1	2.35
185	Caffey disease	Enrichment	COL1A1	2.35
186	Brain small vessel disease 2	Enrichment	COL4A2	2.35
187	Microangiopathy and leukoencephalopathy, pontine, autosomal dominant	Enrichment	COL4A1	2.35
188	Pilarowski-bjornsson syndrome	Enrichment	COL4A3	2.35
189	Alport syndrome 3b, autosomal recessive	Enrichment	COL4A3	2.35
190	Angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps	Enrichment	COL4A1	2.35
191	Hematuria, benign familial, 2	Enrichment	COL4A3	2.35
192	Multiple epiphyseal dysplasia	Enrichment	COL2A1	2.35
193	Hyperpigmentation of the skin	Enrichment	COL7A1	2.35
194	Schwartz-jampel syndrome, type 1	Enrichment	HSPG2	2.35
195	Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome	Enrichment	ITGA3	2.35
196	Glaucoma, primary closed-angle	Enrichment	COL18A1	2.35
197	Cakut	Enrichment	ACTG1, COL4A1	2.35
198	Epidermolysis bullosa simplex	Enrichment	ITGB4	2.25
199	Phenylketonuria	Enrichment	COL1A1	2.23
200	Schizencephaly	Enrichment	COL4A1	2.23
201	Epidermolytic hyperkeratosis	Enrichment	COL7A1	2.23
202	Rare x-linked non-syndromic sensorineural deafness type dfn	Enrichment	COL4A6	2.23
203	Blepharocheilodontic syndrome 1	Enrichment	CTNND1	2.23
204	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	2.23
205	Deafness, autosomal dominant 20	Enrichment	ACTG1	2.23
206	Baraitser-winter syndrome 2	Enrichment	ACTG1	2.23
207	Blepharocheilodontic syndrome 2	Enrichment	CTNND1	2.23
208	Neurodevelopmental disorder with intracranial hemorrhage, seizures, and spasticity	Enrichment	ESAM	2.23
209	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	2.23
210	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	2.23
211	Teratoma	Enrichment	CTNNB1	2.23
212	Congenital muscular dystrophy	Enrichment	LAMA2	2.19
213	Dyssegmental dysplasia, silverman-handmaker type	Enrichment	HSPG2	2.18
214	Muscular dystrophy, congenital, due to integrin alpha-7 deficiency	Enrichment	ITGA7	2.18
215	Isolated dandy-walker malformation without hydrocephalus	Enrichment	NID1	2.18
216	Epidermolytic hyperkeratosis 1	Enrichment	COL7A1	2.13
217	Retinal detachment	Enrichment	COL2A1	2.13
218	Familial cerebral saccular aneurysm	Enrichment	COL3A1	2.13
219	Amelogenesis imperfecta, type ie	Enrichment	LAMB3	2.09
220	Thrombocytopenia	Enrichment	ACTN1, ITGB3	2.06
221	Developmental dysplasia of the hip 1	Enrichment	COL2A1	2.05
222	Anterior segment dysgenesis 5	Enrichment	COL4A1	2.05
223	Inguinal hernia	Enrichment	COL5A1	2.05
224	Pain disorder	Enrichment	COL5A1	2.05
225	Knobloch syndrome	Enrichment	COL18A1	2.05
226	Desmoid disease, hereditary	Enrichment	CTNNB1	2.05
227	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3	2.05
228	Bleeding disorder, platelet-type, 16	Enrichment	ITGB3	2.05
229	Epidermolysis bullosa, lethal acantholytic	Enrichment	JUP	2.05
230	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	2.05
231	Anus, imperforate	Enrichment	CTNNB1	2.05
232	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	2.05
233	Desmoid tumor	Enrichment	CTNNB1	2.05
234	Intrinsic cardiomyopathy	Enrichment	ACTN2	2.05
235	Butterfly-shaped pigment dystrophy	Enrichment	CTNNA1	2.05
236	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	2.05
237	Presynaptic congenital myasthenic syndromes	Enrichment	LAMA5	2.05
238	Nevus, epidermal	Enrichment	COL7A1	1.99
239	Multiple enchondromatosis, maffucci type	Enrichment	COL2A1	1.99
240	Amelogenesis imperfecta	Enrichment	LAMB3	1.98
241	Familial isolated dilated cardiomyopathy	Enrichment	ACTN2, LAMA4	1.97
242	Knobloch syndrome 1	Enrichment	COL18A1	1.96
243	Hereditary breast ovarian cancer syndrome	Enrichment	CTNNA1, CTNNA2	1.94
244	Gastroesophageal reflux	Enrichment	COL5A1	1.93
245	Spastic paraplegia 4, autosomal dominant	Enrichment	COL3A1	1.93
246	Orthostatic intolerance	Enrichment	COL5A1	1.93
247	Diffuse gastric and lobular breast cancer syndrome	Enrichment	CTNNA1	1.93
248	Polyposis syndrome, hereditary mixed, 1	Enrichment	CTNNA1	1.93
249	Pilomatrixoma	Enrichment	CTNNB1	1.93
250	Aminoacylase 1 deficiency	Enrichment	ACTB	1.93
251	Alazami syndrome	Enrichment	CTNNB1	1.93
252	Craniopharyngioma	Enrichment	CTNNB1	1.93
253	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.93
254	Creatine phosphokinase, elevated serum	Enrichment	LAMA2	1.89
255	Isolated elevated serum creatine phosphokinase levels	Enrichment	LAMA2	1.89
256	Familial thoracic aortic aneurysm and dissection	Enrichment	COL3A1	1.88
257	Marfan syndrome	Enrichment	COL2A1	1.83
258	Peters-plus syndrome	Enrichment	COL4A1	1.83
259	Stickler syndrome	Enrichment	COL2A1	1.83
260	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.83
261	Glanzmann thrombasthenia 2	Enrichment	ITGB3	1.83
262	Coloboma of choroid and retina	Enrichment	ACTG1	1.83
263	Focal epilepsy	Enrichment	NID1	1.81
264	Ichthyosis	Enrichment	COL7A1	1.79
265	Cutis laxa	Enrichment	COL5A1	1.76
266	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.76
267	Adrenocortical carcinoma	Enrichment	CTNNB1	1.76
268	Cleft lip with or without cleft palate	Enrichment	CTNND1	1.76
269	Clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly	Enrichment	COL5A1	1.72
270	Neural tube defects	Enrichment	ITGB1	1.72
271	Clubfoot	Enrichment	COL5A1	1.72
272	Aortic aneurysm, familial thoracic 1	Enrichment	COL3A1	1.69
273	Walker-warburg syndrome	Enrichment	COL4A1	1.69
274	Cataract	Enrichment	COL5A1	1.69
275	Isolated macular dystrophy	Enrichment	COL4A5	1.69
276	Glanzmann thrombasthenia 1	Enrichment	ITGB3	1.69
277	Gallbladder cancer	Enrichment	CTNNB1	1.69
278	Anterior segment dysgenesis	Enrichment	COL4A1	1.66
279	Atypical hemolytic-uremic syndrome	Enrichment	COL4A5	1.66
280	Rare genetic deafness	Enrichment	ACTG1, COL4A5	1.65
281	Dilated cardiomyopathy	Enrichment	ACTN2, JUP	1.63
282	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.63
283	Beckwith-wiedemann syndrome	Enrichment	COL7A1	1.58
284	Heart, malformation of	Enrichment	COL2A1	1.58
285	Polycystic kidney disease	Enrichment	COL4A4	1.58
286	Adult hepatocellular carcinoma	Enrichment	CTNNB1	1.58
287	Colorectal cancer	Enrichment	CTNNA1, CTNNB1	1.57
288	Chromosome 1p36 deletion syndrome	Enrichment	HSPG2	1.55
289	Cat eye syndrome	Enrichment	ACTG1	1.54
290	Hepatoblastoma	Enrichment	COL7A1	1.52
291	Congenital myopathy 4a, autosomal dominant	Enrichment	ITGA7	1.49
292	Hydrocephalus	Enrichment	NID1	1.49
293	Charcot-marie-tooth disease	Enrichment	LAMA2	1.48
294	Scoliosis	Enrichment	COL2A1	1.46
295	Medulloblastoma	Enrichment	CTNNB1	1.39
296	Stargardt disease 1	Enrichment	COL2A1	1.36
297	Cystic fibrosis	Enrichment	CEACAM6	1.34
298	Wolff-parkinson-white syndrome	Enrichment	JUP	1.34
299	Polycystic liver disease	Enrichment	CTNNB1	1.31
300	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	1.31
301	Arteriovenous malformations of the brain	Enrichment	CDH2	1.26
302	Craniosynostosis	Enrichment	CTNNA1	1.24
303	Lissencephaly	Enrichment	ACTG1	1.22
304	Severe covid-19	Enrichment	ITGAV	1.21
305	Hepatocellular carcinoma	Enrichment	CTNNB1	1.20
306	Myocardial infarction	Enrichment	ITGB3	1.20
307	Auditory neuropathy	Enrichment	CDH2	1.13
308	Hypertelorism	Enrichment	COL1A1	1.13
309	Long qt syndrome	Enrichment	CTNNA3	1.06
310	Familial hypertrophic cardiomyopathy	Enrichment	ACTN2	1.03
311	Left ventricular noncompaction	Enrichment	ACTN2	1.01
312	Non-syndromic genetic deafness	Enrichment	ACTG1	1.00
313	Nonsyndromic hearing loss	Enrichment	ACTG1	0.93
314	Hypertrophic cardiomyopathy	Enrichment	ACTN2	0.92
315	Hereditary retinal dystrophy	Enrichment	COL18A1, LAMA1	0.87
316	Fundus dystrophy	Enrichment	COL18A1, LAMA1	0.87
317	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ACTG1	0.85
318	Ovarian cancer	Enrichment	CTNNB1	0.59
319	Congenital nervous system abnormality	Enrichment	CTNNB1	0.57
320	Nervous system disease	Enrichment	CTNNB1	0.57
321	Inherited cancer-predisposing syndrome	Enrichment	CTNNA1	0.49
322	Retinitis pigmentosa	Enrichment	COL18A1	0.42

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Biofilm formation

Pathway Network for Biofilm formation

Pathway network for the Biofilm formation SuperPath

Member Pathways for Biofilm formation

Pathways in the Biofilm formation SuperPath

Gene overlap in member pathways for Biofilm formation SuperPath

Associated Genes for Biofilm formation

Associated Disorders for Biofilm formation

Disorders associated with Biofilm formation SuperPath

STRING Interaction Network for Biofilm formation

Sources for Biofilm formation