Biomarkers for urea cycle disorders

No Pathway Network information available for Biomarkers for urea cycle disorders

#	Name	Source	Genes
1	Biomarkers for urea cycle disorders	WikiPathways	ARG1 ASL ASS1 F10 F7 GAMT GATM GLS2 GOT1 GPT NAGS OTC (see all 12) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	GLS2	Glutaminase 2	Protein Coding	1
2	ASS1	Argininosuccinate Synthase 1	Protein Coding	1
3	ASL	Argininosuccinate Lyase	Protein Coding	1
4	NAGS	N-Acetylglutamate Synthase	Protein Coding	1
5	ARG1	Arginase 1	Protein Coding	1
6	OTC	Ornithine Transcarbamylase	Protein Coding	1
7	GATM	Glycine Amidinotransferase	Protein Coding	1
8	GAMT	Guanidinoacetate N-Methyltransferase	Protein Coding	1
9	GOT1	Glutamic-Oxaloacetic Transaminase 1	Protein Coding	1
10	GPT	Glutamic--Pyruvic Transaminase	Protein Coding	1
11	F7	Coagulation Factor VII	Protein Coding	1
12	F10	Coagulation Factor X	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Factor vii deficiency	Enrichment	F7	3.05
2	Argininosuccinic aciduria	Enrichment	ASL	3.05
3	Ornithine transcarbamylase deficiency, hyperammonemia due to	Enrichment	OTC	3.05
4	Aspartate aminotransferase, serum level of, quantitative trait locus 1	Enrichment	GOT1	3.05
5	Disorder of ornithine metabolism	Enrichment	OTC	3.05
6	Congenital factor vii deficiency	Enrichment	F7	3.05
7	Fanconi renotubular syndrome 1	Enrichment	GATM	2.75
8	Citrullinemia, classic	Enrichment	ASS1	2.75
9	Argininemia	Enrichment	ARG1	2.75
10	N-acetylglutamate synthase deficiency	Enrichment	NAGS	2.75
11	Cerebral creatine deficiency syndrome 2	Enrichment	GAMT	2.75
12	Cerebral creatine deficiency syndrome	Enrichment	GAMT	2.75
13	Cerebral creatine deficiency syndrome 3	Enrichment	GATM	2.75
14	Citrullinemia	Enrichment	ASS1	2.75
15	Creatine deficiency disorders	Enrichment	GAMT	2.75
16	Factor x deficiency	Enrichment	F10	2.58
17	Citrin deficiency, adolescent or adult onset	Enrichment	ASS1	2.58
18	Fanconi syndrome	Enrichment	GATM	2.58
19	Congenital factor x deficiency	Enrichment	F10	2.58
20	Glycogen storage disease ia	Enrichment	ASS1	2.45
21	Primary fanconi renotubular syndrome	Enrichment	GATM	2.45
22	Myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency	Enrichment	ASL	2.05
23	Parkinson's disease	Enrichment	GAMT	1.78
24	Myocardial infarction	Enrichment	F7	1.71
25	Parkinson disease, late-onset	Enrichment	GAMT	1.68
26	Thrombocytopenia	Enrichment	F10	1.38
27	Congenital nervous system abnormality	Enrichment	GAMT	1.05
28	Nervous system disease	Enrichment	GAMT	1.05

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Biomarkers for urea cycle disorders