Budding and maturation of HIV virion

Pathway network for the Budding and maturation of HIV virion SuperPath

Sources:

Reactome

Pathways in the Budding and maturation of HIV virion SuperPath

#	Name	Source	Genes
1	Budding and maturation of HIV virion	Reactome	CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CHMP6 CHMP7 MVB12A MVB12B NEDD4L PPIA RNF103-CHMP3 RPS27A TSG101 UBA52 UBAP1 UBB UBC VPS28 VPS37A VPS37B VPS37C VPS37D VPS4A VPS4B VTA1 (see all 28) (see less)
2	Late endosomal microautophagy	Reactome	ARL13B CETN1 CFTR CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 HBB HDAC6 HSPA8 IFT88 MVB12A MVB12B PARK7 PCNT PLIN2 PLIN3 RNASE1 RNF103-CHMP3 RPS27A TSG101 UBA52 UBAP1 UBB UBC VIM VPS28 VPS37A VPS37B VPS37C VPS37D (see all 35) (see less)
3	Endosomal Sorting Complex Required For Transport (ESCRT)	Reactome	CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CHMP6 CHMP7 HGS MVB12A MVB12B RNF103-CHMP3 RPS27A SNF8 STAM STAM2 TSG101 UBA52 UBAP1 UBB UBC VPS25 VPS28 VPS36 VPS37A VPS37B VPS37C VPS37D VPS4A VPS4B VTA1 (see all 32) (see less)
4	Chaperone Mediated Autophagy	Reactome	ARL13B CETN1 CFTR EEF1A1 GFAP HBB HDAC6 HSP90AA1 HSP90AB1 HSPA8 IFT88 LAMP2 PARK7 PCNT PLIN2 PLIN3 RNASE1 RPS27A UBA52 UBB UBC VIM (see all 22) (see less)
5	Synthesis And Processing Of GAG, GAGPOL Polyproteins	Reactome	MVB12A MVB12B NMT2 RPS27A TSG101 UBA52 UBAP1 UBB UBC VPS28 VPS37A VPS37B VPS37C VPS37D (see all 14) (see less)
6	Membrane binding and targetting of GAG proteins	Reactome	MVB12A MVB12B NMT2 RPS27A TSG101 UBA52 UBAP1 UBB UBC VPS28 VPS37A VPS37B VPS37C VPS37D (see all 14) (see less)

Gene overlap in member pathways for Budding and maturation of HIV virion SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RPS27A	Ribosomal Protein S27a	Protein Coding	6
2	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	6
3	UBB	Ubiquitin B	Protein Coding	6
4	UBC	Ubiquitin C	Protein Coding	6
5	VPS37A	VPS37A Subunit Of ESCRT-I	Protein Coding	5
6	VPS37D	VPS37D Subunit Of ESCRT-I	Protein Coding	5
7	VPS28	VPS28 Subunit Of ESCRT-I	Protein Coding	5
8	UBAP1	Ubiquitin Associated Protein 1	Protein Coding	5
9	VPS37C	VPS37C Subunit Of ESCRT-I	Protein Coding	5
10	TSG101	Tumor Susceptibility 101	Protein Coding	5
11	VPS37B	VPS37B Subunit Of ESCRT-I	Protein Coding	5
12	MVB12B	Multivesicular Body Subunit 12B	Protein Coding	5
13	MVB12A	Multivesicular Body Subunit 12A	Protein Coding	5
14	RNF103-CHMP3	RNF103-CHMP3 Readthrough	Protein Coding	3
15	CHMP4B	Charged Multivesicular Body Protein 4B	Protein Coding	3
16	CHMP2B	Charged Multivesicular Body Protein 2B	Protein Coding	3
17	CHMP2A	Charged Multivesicular Body Protein 2A	Protein Coding	3
18	CHMP4A	Charged Multivesicular Body Protein 4A	Protein Coding	3
19	CHMP3	Charged Multivesicular Body Protein 3	Protein Coding	3
20	CHMP6	Charged Multivesicular Body Protein 6	Protein Coding	3
21	CHMP7	Charged Multivesicular Body Protein 7	Protein Coding	3
22	CHMP4C	Charged Multivesicular Body Protein 4C	Protein Coding	3
23	VPS4A	Vacuolar Protein Sorting 4 Homolog A	Protein Coding	2
24	CHMP5	Charged Multivesicular Body Protein 5	Protein Coding	2
25	VTA1	Vesicle Trafficking 1	Protein Coding	2
26	VPS4B	Vacuolar Protein Sorting 4 Homolog B	Protein Coding	2
27	HDAC6	Histone Deacetylase 6	Protein Coding	2
28	PLIN3	Perilipin 3	Protein Coding	2
29	CETN1	Centrin 1	Protein Coding	2
30	CFTR	CF Transmembrane Conductance Regulator	Protein Coding	2
31	PARK7	Parkinsonism Associated Deglycase	Protein Coding	2
32	PLIN2	Perilipin 2	Protein Coding	2
33	ARL13B	ARF Like GTPase 13B	Protein Coding	2
34	HBB	Hemoglobin Subunit Beta	Protein Coding	2
35	HSPA8	Heat Shock Protein Family A (Hsp70) Member 8	Protein Coding	2
36	PCNT	Pericentrin	Protein Coding	2
37	RNASE1	Ribonuclease A Family Member 1, Pancreatic	Protein Coding	2
38	VIM	Vimentin	Protein Coding	2
39	IFT88	Intraflagellar Transport 88	Protein Coding	2
40	NMT2	N-Myristoyltransferase 2	Protein Coding	2
41	NEDD4L	NEDD4 Like E3 Ubiquitin Protein Ligase	Protein Coding	1
42	PPIA	Peptidylprolyl Isomerase A	Protein Coding	1
43	STAM2	Signal Transducing Adaptor Molecule 2	Protein Coding	1
44	SNF8	SNF8 Subunit Of ESCRT-II	Protein Coding	1
45	VPS36	Vacuolar Protein Sorting 36 Homolog	Protein Coding	1
46	STAM	Signal Transducing Adaptor Molecule	Protein Coding	1
47	VPS25	Vacuolar Protein Sorting 25 Homolog	Protein Coding	1
48	HGS	Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate	Protein Coding	1
49	EEF1A1	Eukaryotic Translation Elongation Factor 1 Alpha 1	Protein Coding	1
50	GFAP	Glial Fibrillary Acidic Protein	Protein Coding	1
51	HSP90AA1	Heat Shock Protein 90 Alpha Family Class A Member 1	Protein Coding	1
52	HSP90AB1	Heat Shock Protein 90 Alpha Family Class B Member 1	Protein Coding	1
53	LAMP2	Lysosomal Associated Membrane Protein 2	Protein Coding	1

Disorders associated with Budding and maturation of HIV virion SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Human immunodeficiency virus infectious disease	Direct
2	Chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia	Enrichment	HDAC6	2.79
3	Joubert syndrome 8	Enrichment	ARL13B	2.79
4	Microcephalic osteodysplastic primordial dwarfism, type ii	Enrichment	PCNT	2.79
5	Danon disease	Enrichment	LAMP2	2.79
6	Parkinson disease 7, autosomal recessive early-onset	Enrichment	PARK7	2.79
7	Sickle cell-beta-thalassemia disease syndrome	Enrichment	HBB	2.79
8	Hemoglobin c-beta-thalassemia syndrome	Enrichment	HBB	2.79
9	Aquagenic palmoplantar keratoderma	Enrichment	CFTR	2.79
10	Sickle cell s-o arab disease	Enrichment	HBB	2.79
11	Sickle cell-beta zero-thalassemia	Enrichment	HBB	2.79
12	Sickle cell s-d punjab disease	Enrichment	HBB	2.79
13	Premature aging	Enrichment	VIM	2.79
14	Sickle cell s-c disease	Enrichment	HBB	2.79
15	Sickle cell s-e disease	Enrichment	HBB	2.79
16	Homozygous hemoglobin o arab disease	Enrichment	HBB	2.79
17	Sickle cell s-other specified hemoglobin variant	Enrichment	HBB	2.79
18	Cataract 31, multiple types	Enrichment	CHMP4B	2.63
19	Spastic paraplegia 53, autosomal recessive	Enrichment	VPS37A	2.63
20	Developmental and epileptic encephalopathy 115	Enrichment	SNF8	2.63
21	Spastic paraplegia 80, autosomal dominant	Enrichment	UBAP1	2.63
22	Neurodevelopmental disorder plus optic atrophy	Enrichment	SNF8	2.63
23	Amyotrophic lateral sclerosis-parkinsonism/dementia complex 1	Enrichment	PARK7	2.49
24	Alexander disease	Enrichment	GFAP	2.49
25	Spermatogenic failure, y-linked, 2	Enrichment	CFTR	2.49
26	Spastic paraplegia, intellectual disability, nystagmus, and obesity	Enrichment	GFAP	2.49
27	Cataract 30	Enrichment	VIM	2.49
28	Hemoglobin lepore-beta-thalassemia syndrome	Enrichment	HBB	2.49
29	Sickle cell s-lepore disease	Enrichment	HBB	2.49
30	Submucosal cleft palate	Enrichment	UBB	2.49
31	Cleft hard palate	Enrichment	UBB	2.49
32	Spastic paraplegia 12, autosomal dominant	Enrichment	UBAP1	2.33
33	Cimdag syndrome	Enrichment	VPS4A	2.33
34	Uvula, bifid	Enrichment	UBB	2.31
35	Nuchal bleb, familial	Enrichment	CFTR	2.31
36	Cleft soft palate	Enrichment	UBB	2.31
37	Hemoglobin e disease	Enrichment	HBB	2.31
38	Sickle cell-hemoglobin c disease	Enrichment	HBB	2.31
39	Hemoglobin d disease	Enrichment	HBB	2.31
40	Delta beta-thalassemia	Enrichment	HBB	2.31
41	Unstable hemoglobin disease	Enrichment	HBB	2.31
42	Hemoglobin e/beta thalassemia disease	Enrichment	HBB	2.31
43	Sickle cell disease	Enrichment	HBB	2.19
44	Beta-thalassemia, dominant inclusion body type	Enrichment	HBB	2.19
45	Erythrocytosis, familial, 6	Enrichment	HBB	2.19
46	Beta-thalassemia intermedia	Enrichment	HBB	2.19
47	Hemoglobinopathy	Enrichment	HBB	2.19
48	Idiopathic bronchiectasis	Enrichment	CFTR	2.19
49	Hemoglobin c disease	Enrichment	HBB	2.19
50	Hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome	Enrichment	HBB	2.19
51	Methemoglobinemia, beta-globin type	Enrichment	HBB	2.19
52	Thalassemia	Enrichment	HBB	2.09
53	Histiocytoid hemangioma	Enrichment	VIM	2.09
54	Hereditary persistence of fetal hemoglobin-sickle cell disease syndrome	Enrichment	HBB	2.09
55	Dentin dysplasia, type i	Enrichment	VPS4B	2.03
56	Metachromatic leukodystrophy	Enrichment	GFAP	2.01
57	Parkinson disease 6, autosomal recessive early-onset	Enrichment	PARK7	2.01
58	Methemoglobinemia, beta type	Enrichment	HBB	2.01
59	Autosomal dominant secondary polycythemia	Enrichment	HBB	2.01
60	Beta-thalassemia	Enrichment	HBB	1.95
61	Beta-thalassemia major	Enrichment	HBB	1.95
62	Hemolytic anemia	Enrichment	HBB	1.95
63	Cataract 6, multiple types	Enrichment	CHMP4B	1.93
64	Heinz body anemias	Enrichment	HBB	1.89
65	Fetal hemoglobin quantitative trait locus 1	Enrichment	HBB	1.89
66	Heinz body anemia	Enrichment	HBB	1.89
67	Bronchiectasis with or without elevated sweat chloride 1	Enrichment	CFTR	1.84
68	Vas deferens, congenital bilateral aplasia of	Enrichment	CFTR	1.84
69	Alpha-thalassemia	Enrichment	HBB	1.84
70	Cataract 30, multiple types	Enrichment	VIM	1.79
71	Semantic dementia	Enrichment	CHMP2B	1.79
72	Early-onset posterior polar cataract	Enrichment	CHMP4B	1.73
73	Early-onset parkinson's disease	Enrichment	PARK7	1.71
74	Protein-deficiency anemia	Enrichment	HBB	1.68
75	Progressive non-fluent aphasia	Enrichment	CHMP2B	1.68
76	Behavioral variant of frontotemporal dementia	Enrichment	CHMP2B	1.68
77	Seckel syndrome	Enrichment	PCNT	1.65
78	Hereditary chronic pancreatitis	Enrichment	CFTR	1.65
79	Atypical hemolytic-uremic syndrome	Enrichment	HBB	1.62
80	Lynch syndrome	Enrichment	CFTR	1.62
81	Pancreatitis, hereditary	Enrichment	CFTR	1.56
82	Malaria	Enrichment	HBB	1.44
83	Scoliosis	Enrichment	GFAP	1.42
84	Williams-beuren syndrome	Enrichment	VPS37D	1.34
85	Isolated joubert syndrome	Enrichment	ARL13B	1.32
86	Cystic fibrosis	Enrichment	CFTR	1.30
87	Familial hypertrophic cardiomyopathy	Enrichment	LAMP2	1.28
88	Male infertility	Enrichment	CFTR	1.27
89	Left ventricular noncompaction	Enrichment	LAMP2	1.26
90	Hypertrophic cardiomyopathy	Enrichment	LAMP2	1.17
91	Joubert syndrome 1	Enrichment	ARL13B	1.11
92	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	CFTR	1.06
93	Dilated cardiomyopathy	Enrichment	LAMP2	0.91
94	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	CHMP2B	0.89
95	Retinitis pigmentosa	Enrichment	IFT88	0.53

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Budding and maturation of HIV virion

Pathway Network for Budding and maturation of HIV virion

Pathway network for the Budding and maturation of HIV virion SuperPath

Member Pathways for Budding and maturation of HIV virion

Pathways in the Budding and maturation of HIV virion SuperPath

Gene overlap in member pathways for Budding and maturation of HIV virion SuperPath

Associated Genes for Budding and maturation of HIV virion

Associated Disorders for Budding and maturation of HIV virion

Disorders associated with Budding and maturation of HIV virion SuperPath

STRING Interaction Network for Budding and maturation of HIV virion

Sources for Budding and maturation of HIV virion