C-MYB transcription factor network

No Pathway Network information available for C-MYB transcription factor network

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

Disorders associated with C-MYB transcription factor network SuperPath

according to GeneCards Suite gene sharing
#DisorderTypeGenesScore
1Acute basophilic leukemiaEnrichmentGATA1, MYB4.46
2High-grade b-cell lymphoma double-hit/triple-hitEnrichmentBCL2, MYC3.99
3Precursor t-cell acute lymphoblastic leukemiaEnrichmentCDKN2A, MYB, MYC3.49
4Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negativeEnrichmentADA, RAG23.47
5Acute myeloid leukemia with t(8;21)(q22;q22) translocationEnrichmentCEBPA, KIT3.47
6Myopathy, centronuclear, 1EnrichmentMYF6, MYOD13.29
7Testicular germ cell tumorEnrichmentKIT, KITLG3.29
8Multiple endocrine neoplasia, type iEnrichmentCDKN1A, CDKN1B3.15
9Omenn syndromeEnrichmentADA, RAG22.82
10Leukemia, acute myeloidEnrichmentCEBPA, KIT, NRAS2.78
11Leukemia, acute lymphoblasticEnrichmentCDKN2A, PAX52.74
12Lip and oral cavity carcinomaEnrichmentCDKN2A, KIT2.66
13Osteogenesis imperfecta, type ivEnrichmentCOL1A2, WNT12.59
14Alzheimer's diseaseEnrichmentCSF1R, MPO2.59
15Protein-deficiency anemiaEnrichmentGATA1, NRAS2.59
16OsteoporosisEnrichmentCOL1A2, WNT12.53
17Osteogenesis imperfecta, type iiiEnrichmentCOL1A2, WNT12.46
18Alzheimer disease, familial, 1EnrichmentCSF1R, MPO2.36
19Cardiospondylocarpofacial syndromeEnrichmentMAP3K72.23
20Ehlers-danlos syndrome, cardiac valvular typeEnrichmentCOL1A22.23
21Anemia, congenital, nonspherocytic hemolytic, 9EnrichmentGATA12.23
22Thrombocytopenia, x-linked, with or without dyserythropoietic anemiaEnrichmentGATA12.23
23Thrombocytopenia with beta-thalassemia, x-linkedEnrichmentGATA12.23
24Cataract 21, multiple typesEnrichmentMAF2.23
25Mastocytosis, cutaneousEnrichmentKIT2.23
26Hyperpigmentation with or without hypopigmentation, familial progressiveEnrichmentKITLG2.23
27Microcephaly 12, primary, autosomal recessiveEnrichmentCDK62.23
28Melanosis, neurocutaneousEnrichmentNRAS2.23
29Noonan syndrome 6EnrichmentNRAS2.23
30Shprintzen-goldberg craniosynostosis syndromeEnrichmentSKI2.23
31Frontometaphyseal dysplasia 2EnrichmentMAP3K72.23
32Ectodermal dysplasia 17 with or without limb malformationsEnrichmentLEF12.23
33Agammaglobulinemia 10, autosomal dominantEnrichmentSPI12.23
34Intellectual developmental disorder, autosomal dominant 66EnrichmentATP2B12.23
35Immunodeficiency 85 and autoimmunityEnrichmentTOM12.23
36Developmental and epileptic encephalopathy 91EnrichmentPPP3CA2.23
37Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual developmentEnrichmentPPP3CA2.23
38Combined osteogenesis imperfecta and ehlers-danlos syndrome 2EnrichmentCOL1A22.23
39Anemia, x-linked, with or without neutropenia and/or platelet abnormalitiesEnrichmentGATA12.23
40Okt4 epitope deficiencyEnrichmentCD42.23
41Ayme-gripp syndromeEnrichmentMAF2.23
42Bone mineral density quantitative trait locus 16EnrichmentWNT12.23
43Immunodeficiency 54EnrichmentMCM42.23
44Skin/hair/eye pigmentation, variation in, 7EnrichmentKITLG2.23
45Atrial fibrillation, familial, 8EnrichmentZFHX32.23
46Neuroendocrine tumorEnrichmentCDKN1B2.23
47Congenital myopathy 17EnrichmentMYOD12.23
48Immunoglobulin light chain amyloidosisEnrichmentLYZ2.23
49Autoinflammation and autoimmunity, systemic, with immune dysregulationEnrichmentCOPA2.23
50Blepharophimosis-impaired intellectual development syndromeEnrichmentSMARCA22.23
51Amyloidosis, hereditary systemic 5EnrichmentLYZ2.23
52Menke-hennekam syndrome 1EnrichmentCREBBP2.23
53Brain abnormalities, neurodegeneration, and dysosteosclerosisEnrichmentCSF1R2.23
54Immunodeficiency 79EnrichmentCD42.23
55Chronic mast cell leukemiaEnrichmentKIT2.23
56Deafness, autosomal dominant 69EnrichmentKITLG2.23
57Acute megakaryoblastic leukemia in children with down syndromeEnrichmentGATA12.23
58Recombinase activating gene 2 deficiencyEnrichmentRAG22.23
59Cdkn2a cancer predispositionEnrichmentCDKN2A2.23
60Mosaic variegated aneuploidy syndrome 7 with inflammation and tumor predispositionEnrichmentMAD1L12.23
61Csf1r-related disorderEnrichmentCSF1R2.23
62Rubinstein-taybi syndrome due to 16p13.3 microdeletionEnrichmentCREBBP2.23
63Immunodeficiency 126EnrichmentPTCRA2.23
64Thrombocytopenia with congenital dyserythropoietic anemiaEnrichmentGATA12.23
65Chromosome 15q24 deletion syndromeEnrichmentSIN3A2.23
66AgammaglobulinemiaEnrichmentSPI12.23
67Isolated bone marrow mastocytosisEnrichmentKIT2.23
68Smoldering systemic mastocytosisEnrichmentKIT2.23
69Wilms tumor 7EnrichmentTRIM282.23
70Acute myeloid leukemia with mutated cebpaEnrichmentCEBPA2.23
71MastocytosisEnrichmentKIT2.23
72Menke-hennekam syndromeEnrichmentCREBBP2.23
73Familial progressive hyperpigmentationEnrichmentKITLG2.23
74Early-onset calcifying leukoencephalopathy-skeletal dysplasiaEnrichmentCSF1R2.23
75Cutaneous mastocytomaEnrichmentKIT2.23
76Typical urticaria pigmentosaEnrichmentKIT2.23
77Nodular urticaria pigmentosaEnrichmentKIT2.23
78Pseudoxanthomatous diffuse cutaneous mastocytosisEnrichmentKIT2.23
79Telangiectasia macularis eruptiva perstansEnrichmentKIT2.23
80Acute mast cell leukemiaEnrichmentKIT2.23
81Familial progressive hyper- and hypopigmentationEnrichmentKITLG2.23
82Plaque-form urticaria pigmentosaEnrichmentKIT2.23
83Neurocutaneous melanocytosisEnrichmentNRAS2.23
84Bullous diffuse cutaneous mastocytosisEnrichmentKIT2.23
85Testis seminomaEnrichmentKIT2.23
86Inherited cancer-predisposing syndromeEnrichmentCDKN1B, CDKN2A, CEBPA, KIT2.12
87Brittle bone disorderEnrichmentCOL1A2, WNT12.10
88Myeloproliferative syndrome, transientEnrichmentGATA11.93
89Ectrodactyly and ectodermal dysplasia without cleft lip/palateEnrichmentLEF11.93
90Melanoma-astrocytoma syndromeEnrichmentCDKN2A1.93
91Burkitt lymphomaEnrichmentMYC1.93
92Cyclic neutropeniaEnrichmentELANE1.93
93Hypoparathyroidism, sensorineural deafness, and renal dysplasia syndromeEnrichmentGATA31.93
94Bruck syndrome 1EnrichmentCOL1A21.93
95Thumb deformityEnrichmentCREBBP1.93
96Neutropenia, severe congenital, x-linkedEnrichmentELANE1.93
97Porphyria, congenital erythropoieticEnrichmentGATA11.93
98Mitochondrial phosphate carrier deficiencyEnrichmentSLC25A31.93
99Piebald traitEnrichmentKIT1.93
100Osteogenesis imperfecta, type xvEnrichmentWNT11.93
101Melanoma, cutaneous malignant 2EnrichmentCDKN2A1.93
102Ras-associated autoimmune leukoproliferative disorderEnrichmentNRAS1.93
103Developmental and epileptic encephalopathy 28EnrichmentMAF1.93
104Multiple endocrine neoplasia, type ivEnrichmentCDKN1B1.93
105Spinocerebellar ataxia, autosomal recessive 12EnrichmentMAF1.93
106Waardenburg syndrome, type 2fEnrichmentKITLG1.93
107Ehlers-danlos syndrome, arthrochalasia type, 2EnrichmentCOL1A21.93
108Intravascular large b-cell lymphomaEnrichmentBCL21.93
109Acute myeloid leukemia with kat6a-crebbp fusionEnrichmentCREBBP1.93
110Split hand-foot malformationEnrichmentLEF11.93
111Melanoma-pancreatic cancer syndromeEnrichmentCDKN2A1.93
112Witteveen-kolk syndromeEnrichmentSIN3A1.93
113Angiocentric gliomaEnrichmentMYB1.93
114B-lymphoblastic leukemia/lymphoma with hyperdiploidyEnrichmentGATA31.93
115Hypoparathyroidism-deafness-renal disease syndromeEnrichmentGATA31.93
116Blepharophimosis - intellectual disability syndromeEnrichmentSMARCA21.93
117Ehlers-danlos/osteogenesis imperfecta syndromeEnrichmentCOL1A21.93
118Autosomal dominant nonsyndromic deafnessEnrichmentGATA31.93
119Cardiomyopathy-hypotonia-lactic acidosis syndromeEnrichmentSLC25A31.93
120Dentinogenesis imperfectaEnrichmentCOL1A21.93
121B-lymphoblastic leukemia/lymphoma with tEnrichmentKIT1.93
122B-lymphoblastic leukemia/lymphoma with t(7;9)(q11.2;p13.2)EnrichmentPAX51.93
123Bladder cancerEnrichmentCDKN1A, CDKN2A1.90
124Prostate cancerEnrichmentMAD1L1, ZFHX31.90
125Severe combined immunodeficiencyEnrichmentADA, RAG21.79
126Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-negative, nk cell-negative, due to adenosine deaminase deficiencyEnrichmentADA1.75
127Jacobsen syndromeEnrichmentETS11.75
128Neutropenia, severe congenital, 1, autosomal dominantEnrichmentELANE1.75
129Combined cellular and humoral immune defects with granulomasEnrichmentRAG21.75
130Leukoencephalopathy, hereditary diffuse, with spheroids 1EnrichmentCSF1R1.75
131Spinocerebellar ataxia 4EnrichmentZFHX31.75
132Langerhans cell histiocytosisEnrichmentNRAS1.75
133Osteoporosis, juvenileEnrichmentWNT11.75
134Tethered spinal cord syndromeEnrichmentCREBBP1.75
135Large congenital melanocytic nevusEnrichmentNRAS1.75
136Testicular germ cell cancerEnrichmentKIT1.75
137Frontometaphyseal dysplasiaEnrichmentMAP3K71.75
138Intraocular pressure quantitative trait locusEnrichmentCREBBP1.75
139End stage renal diseaseEnrichmentGATA31.75
140Intellectual developmental disorder, autosomal dominant 30, with speech delay and behavioral abnormalitiesEnrichmentATP2B11.75
141Adenoid cystic carcinomaEnrichmentMYB1.75
142High bone mass osteogenesis imperfectaEnrichmentCOL1A21.75
143Ovarian cancerEnrichmentCDKN1B, CDKN2A, KIT1.66
144Ehlers-danlos syndrome, arthrochalasia type, 1EnrichmentCOL1A21.63
145Schimmelpenning-feuerstein-mims syndromeEnrichmentNRAS1.63
146Myeloperoxidase deficiencyEnrichmentMPO1.63
147Down syndromeEnrichmentGATA11.63
148Nicolaides-baraitser syndromeEnrichmentSMARCA21.63
149Infantile sialic acid storage diseaseEnrichmentRAG21.63
150Salla diseaseEnrichmentRAG21.63
151Mantle cell lymphomaEnrichmentCCND11.63
152BlepharophimosisEnrichmentSMARCA21.63
153Chronic myelogenous leukemia, bcr-abl1 positiveEnrichmentNRAS1.63
154Smarca2-related nicolaides-baraitser syndromeEnrichmentSMARCA21.63
155Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)EnrichmentKIT1.63
156Adenosine deaminase deficiencyEnrichmentADA1.63
157Congenital blue dot cataractEnrichmentMAF1.63
158Osteogenesis imperfecta with normal sclerae, dominant formEnrichmentCOL1A21.63
159Primary hyperparathyroidismEnrichmentCDKN1B1.63
160Systemic mastocytosis with associated hematologic neoplasmEnrichmentKIT1.63
161Familial thoracic aortic aneurysm and aortic dissectionEnrichmentMAT2A, SKI1.56
162Lymphoma, mucosa-associated lymphoid typeEnrichmentBIRC31.54
163Amyloidosis, hereditary systemic 2EnrichmentLYZ1.54
164Von hippel-lindau syndromeEnrichmentCCND11.54
165Mosaic variegated aneuploidy syndrome 1EnrichmentMAD1L11.54
166Goldberg-shprintzen syndromeEnrichmentSKI1.54
167Follicular lymphomaEnrichmentBCL21.54
168Acute myeloid leukemia with maturationEnrichmentKIT1.54
169Acute megakaryocytic leukemiaEnrichmentGATA11.54
170Autosomal dominant severe congenital neutropeniaEnrichmentELANE1.54
171Inherited acute myeloid leukemiaEnrichmentCEBPA1.54
172Free sialic acid storage disorderEnrichmentRAG21.54
173Ehlers-danlos syndrome, classic type, 1EnrichmentCOL1A21.46
174Li-fraumeni syndromeEnrichmentCDKN2A1.46
175Osteogenesis imperfecta, type iEnrichmentCOL1A21.46
176Rubinstein-taybi syndrome 1EnrichmentCREBBP1.46
177Split-hand/foot malformation 1EnrichmentLEF11.46
178Pierre robin syndromeEnrichmentATP2B11.46
179Wilms tumor 5EnrichmentTRIM281.46
180Chromosome 16p13.3 deletion syndrome, proximalEnrichmentCREBBP1.46
181Granulomatosis with polyangiitisEnrichmentPRTN31.46
182Adrenocortical carcinomaEnrichmentCDKN2A1.46
183Lung squamous cell carcinomaEnrichmentCDKN2A1.46
184HypertrichosisEnrichmentCREBBP1.46
185Classic ehlers-danlos syndromeEnrichmentCOL1A21.46
186Nevus, epidermalEnrichmentNRAS1.39
187Osteogenesis imperfecta, type iiEnrichmentCOL1A21.39
188Thyroid cancer, nonmedullary, 2EnrichmentNRAS1.39
189Gastrointestinal stromal tumorEnrichmentKIT1.39
190Waardenburg syndrome, type 2eEnrichmentKITLG1.39
191Leukemia, chronic myeloidEnrichmentNRAS1.39
192NeutropeniaEnrichmentELANE1.39
193Alzheimer's disease 1EnrichmentMPO1.39
194Common variable immunodeficiencyEnrichmentRAG21.39
195Follicular thyroid carcinomaEnrichmentNRAS1.39
196B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)EnrichmentCDKN2A1.39
197Myeloma, multipleEnrichmentCCND1, CREBBP1.37
198Melanocytic nevus syndrome, congenitalEnrichmentNRAS1.34
199Mosaic variegated aneuploidy syndromeEnrichmentMAD1L11.34
200Cataract - microcornea syndromeEnrichmentMAF1.34
201Leukemia, acute lymphoblastic 3EnrichmentPAX51.29
202Cataract 30, multiple typesEnrichmentMAF1.24
203Leukemia, chronic lymphocyticEnrichmentCCND11.24
204MelanomaEnrichmentCDKN2A1.24
205Autosomal non-syndromic agammaglobulinemiaEnrichmentSPI11.24
206Primary bone dysplasiaEnrichmentCOL1A21.24
207Immune deficiency diseaseEnrichmentRAG21.20
208Frontotemporal dementia 1EnrichmentCSF1R1.20
209OsteochondrodysplasiaEnrichmentCOL1A21.20
210Lung non-small cell carcinomaEnrichmentNRAS1.20
211AutismEnrichmentATP2B1, CREBBP1.17
212Juvenile myelomonocytic leukemiaEnrichmentNRAS1.16
213Clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactylyEnrichmentATP2B11.13
214ClubfootEnrichmentATP2B11.13
215Chromosome 1p36 deletion syndromeEnrichmentSKI1.13
216Periventricular nodular heterotopiaEnrichmentATP2B11.10
217Heart diseaseEnrichmentCREBBP1.10
218Pituitary stalk interruption syndromeEnrichmentSMARCA21.10
219Wilms tumor 1EnrichmentTRIM281.07
220Corpus callosum, agenesis ofEnrichmentCREBBP1.07
221Isolated corpus callosum agenesisEnrichmentCREBBP1.07
222Rare genetic intellectual disabilityEnrichmentCREBBP1.07
223Intellectual disability-hypoplastic corpus callosum-preauricular tag syndromeEnrichmentCREBBP1.07
224Noonan syndrome and noonan-related syndromeEnrichmentNRAS1.07
225Colorectal cancerEnrichmentCCND1, NRAS1.03
226Melanoma, cutaneous malignant 1EnrichmentCDKN2A1.02
227Diffuse large b-cell lymphomaEnrichmentCREBBP0.97
228Ehlers-danlos syndromeEnrichmentCOL1A20.97
229Diamond-blackfan anemia 1EnrichmentGATA10.90
230Noonan syndrome 1EnrichmentNRAS0.90
231Autoinflammatory diseaseEnrichmentELANE0.88
232ScoliosisEnrichmentCREBBP0.88
233Pancreatic cancerEnrichmentCDKN2A0.86
234Developmental and epileptic encephalopathy 1EnrichmentMAF0.86
235RasopathyEnrichmentNRAS0.85
236Differentiated thyroid carcinomaEnrichmentNRAS0.80
237Primary autosomal recessive microcephalyEnrichmentCDK60.76
238CakutEnrichmentGATA30.74
239Diamond-blackfan anemiaEnrichmentGATA10.72
240Fetal akinesia deformation sequence 1EnrichmentMYOD10.71
241Systemic lupus erythematosusEnrichmentETS10.69
242Benign epilepsy with centrotemporal spikesEnrichmentMAF0.67
243Distal arthrogryposisEnrichmentMYOD10.66
244Centralopathic epilepsyEnrichmentMAF0.65
245Gastric cancerEnrichmentCDKN2A0.65
246West syndromeEnrichmentMAF0.64
247ThrombocytopeniaEnrichmentGATA10.61
248Autosomal dominant non-syndromic intellectual disabilityEnrichmentPPP3CA0.59
249Rare autosomal dominant non-syndromic sensorineural deafness type dfnaEnrichmentKITLG0.58
250Undetermined early-onset epileptic encephalopathyEnrichmentPPP3CA0.55
251Frontotemporal dementia and/or amyotrophic lateral sclerosis 7EnrichmentCSF1R0.54
252Congenital nervous system abnormalityEnrichmentCREBBP0.33
253Nervous system diseaseEnrichmentCREBBP0.33
254Complex neurodevelopmental disorderEnrichmentATP2B10.28

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