PathCards :: Cardiac conduction Pathway and related pathways

Cardiac conduction SuperPath

Pathway network for Cardiac conduction SuperPath

17 Pathways in the Cardiac conduction SuperPath

	Tandem pore domain halothane-inhibited K+ channel (THIK)		Phase 3 - rapid repolarisation
	Tandem pore domain potassium channels		Physiological factors
	TWIK related potassium channel (TREK)		Cardiac conduction
	Ion homeostasis		Ion transport by P-type ATPases
	TWIK-related spinal cord K+ channel (TRESK)		Phase 2 - plateau phase
	Classical Kir channels		Phase 1 - inactivation of fast Na+ channels
	Phase 4 - resting membrane potential		Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)
	TWIK-related alkaline pH activated K+ channel (TALK)		Muscle contraction
	TWIK-releated acid-sensitive K+ channel (TASK)

232 Genes in the Cardiac conduction SuperPath

KCNK13	KCNK7	KCNK18	KCNK1	KCNK2	KCNK3	KCNK4	KCNK9	KCNK10	KCNK16	KCNK17	KCNK6
KCNE3	AKAP9	KCNE5	KCNE4	KCNE1	KCNQ1	KCNE2	KCNJ2	KCNJ4	KCNJ12	KCNJ14	ATP1A1
ATP1A2	ATP1A3	ATP1A4	ATP1B1	ATP1B2	ATP1B3	FXYD2	ATP2A1	ATP2A2	ATP2A3	ATP2B1	ATP2B2
ATP2B3	ATP2B4	FXYD1	FXYD3	PLN	FXYD7	FXYD6	FXYD4	SLN	SRI	CALM1	CALM2
CALM3	CAMK2A	CAMK2B	CAMK2D	CAMK2G	KCNA5	KCNH2	CES1	CORIN	NKX2-5	HIPK1	WWTR1
GATA4	HIPK2	MME	NPPA	NPPC	NPR1	NPR2	TBX5	KAT2B	ABCC9	TRDN	AHCYL1
CLIC2	DMPK	FKBP1B	CACNG4	KCNIP3	KCNIP2	KCNIP1	ITPR1	ITPR2	ITPR3	KCND1	KCND2
KCND3	KCNJ11	ASPH	NOS1	PRKACA	KCNK12	CACNG8	CACNG7	CACNG6	KCNK15	RYR1	RYR2
RYR3	SLC8A2	SLC8A1	SLC8A3	STIM1	TNNI3	TRPC1	CACNA1C	CACNB1	CACNB2	ORAI2	KCNIP4
CASQ1	CASQ2	ORAI1	KCNK5	CACNA2D2	SCN11A	FGF11	FGF12	FGF13	FGF14	RANGRF	SCN3B
SCN1A	SCN1B	SCN2A	SCN2B	SCN3A	SCN4A	SCN4B	SCN5A	SCN7A	SCN8A	SCN9A	SCN10A
ATP9A	ATP8A1	ATP8B3	ATP10B	ATP11B	ATP11A	ATP13A2	ATP2C1	ATP11C	ATP13A5	ATP9B	ATP12A
ATP4A	ATP4B	CUTC	PDZD11	ATP8A2	ATP8B1	ATP7A	ATP7B	ATP13A1	ATP10A	ATP8B2	ATP10D
ATP8B4	ATP13A4	ATP2C2	SORBS3	MYL12B	MYL9	SORBS1	MYL12A	MYL6B	DES	DMD	ALDH2
LMOD1	TMOD4	TMOD3	TMOD2	GUCY1A2	GUCY1A1	GUCY1B1	MYL11	ANXA1	ANXA2	ANXA6	ITGA1
ITGB5	MYBPC1	MYBPC2	MYBPC3	MYH3	MYH6	MYH8	MYH11	MYL1	MYL2	MYL3	MYL4
MYL5	MYL6	MYLK	NEB	TRIM72	PAK1	PAK2	ACTA1	PXN	MYL7	ACTA2	ACTC1
TLN1	TMOD1	TNNC2	TNNC1	TNNI1	TNNI2	TNNT1	TNNT2	TNNT3	TPM1	TPM2	TPM3
TPM4	ACTG2	TTN	VCL	VIM	CALD1	DYSF	TCAP	CAV3	PDE5A	ACTN2	ACTN3
CACNA1I	CACNA1H	CACNA1G	MYL10

*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.

STRING interaction network for Cardiac conduction SuperPath