Cardiomyocyte Differentiation through BMP Receptors

No Pathway Network information available for Cardiomyocyte Differentiation through BMP Receptors

Pathways in the Cardiomyocyte Differentiation through BMP Receptors SuperPath

#	Name	Source	Genes
1	Cardiomyocyte Differentiation through BMP Receptors	QIAGEN	ATF2 BMP10 BMP2 BMP4 BMP5 BMP7 BMPR1A BMPR1B BMPR2 GATA4 MAP3K7 MEF2C MYH7 MYH7B MYL2 NKX2-5 NPPA NPPB SMAD1 SMAD4 SMAD5 SMAD9 (see all 22) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ATF2	Activating Transcription Factor 2	Protein Coding	1
2	BMP10	Bone Morphogenetic Protein 10	Protein Coding	1
3	BMP2	Bone Morphogenetic Protein 2	Protein Coding	1
4	BMP4	Bone Morphogenetic Protein 4	Protein Coding	1
5	BMP5	Bone Morphogenetic Protein 5	Protein Coding	1
6	BMP7	Bone Morphogenetic Protein 7	Protein Coding	1
7	BMPR1A	Bone Morphogenetic Protein Receptor Type 1A	Protein Coding	1
8	BMPR1B	Bone Morphogenetic Protein Receptor Type 1B	Protein Coding	1
9	BMPR2	Bone Morphogenetic Protein Receptor Type 2	Protein Coding	1
10	GATA4	GATA Binding Protein 4	Protein Coding	1
11	SMAD1	SMAD Family Member 1	Protein Coding	1
12	SMAD4	SMAD Family Member 4	Protein Coding	1
13	SMAD5	SMAD Family Member 5	Protein Coding	1
14	SMAD9	SMAD Family Member 9	Protein Coding	1
15	MAP3K7	Mitogen-Activated Protein Kinase Kinase Kinase 7	Protein Coding	1
16	MEF2C	Myocyte Enhancer Factor 2C	Protein Coding	1
17	MYH7	Myosin Heavy Chain 7	Protein Coding	1
18	MYH7B	Myosin Heavy Chain 7B	Protein Coding	1
19	MYL2	Myosin Light Chain 2	Protein Coding	1
20	NKX2-5	NK2 Homeobox 5	Protein Coding	1
21	NPPA	Natriuretic Peptide A	Protein Coding	1
22	NPPB	Natriuretic Peptide B	Protein Coding	1

Disorders associated with Cardiomyocyte Differentiation through BMP Receptors SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Ventricular septal defect 1	Enrichment	BMP2, BMP7, GATA4	7.43
2	Heart disease	Enrichment	GATA4, MYL2, NKX2-5	5.88
3	Familial atrial fibrillation	Enrichment	GATA4, NKX2-5, NPPA	5.13
4	Juvenile polyposis syndrome	Enrichment	BMPR1A, SMAD4	5.12
5	Pulmonary arterial hypertension associated with congenital heart disease	Enrichment	BMPR2, SMAD9	5.12
6	Brachydactyly, type a2	Enrichment	BMP2, BMPR1B	4.82
7	Left ventricular noncompaction	Enrichment	MYH7, MYH7B, NKX2-5	4.63
8	Congenital heart defects, multiple types, 4	Enrichment	BMP7, GATA4	4.60
9	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	BMPR1A, SMAD4	4.60
10	Hypertrophic cardiomyopathy	Enrichment	MYH7, MYH7B, MYL2	4.36
11	Heritable pulmonary arterial hypertension	Enrichment	BMPR2, SMAD9	3.86
12	Congenital myopathy 4a, autosomal dominant	Enrichment	MYH7, MYL2	3.58
13	Dilated cardiomyopathy	Enrichment	MYH7, MYL2, NKX2-5	3.55
14	Cardiomyopathy, dilated, 1e	Enrichment	MYH7, MYL2	3.47
15	Patent foramen ovale	Enrichment	GATA4, NKX2-5	3.42
16	Cardiomyopathy, familial hypertrophic, 1	Enrichment	MYH7, MYH7B	3.17
17	Tetralogy of fallot	Enrichment	GATA4, NKX2-5	3.10
18	Familial hypertrophic cardiomyopathy	Enrichment	MYH7, MYL2	2.89
19	Atrial septal defect 7 with or without atrioventricular conduction defects	Enrichment	NKX2-5	2.79
20	Cardiospondylocarpofacial syndrome	Enrichment	MAP3K7	2.79
21	Hypothyroidism, congenital, nongoitrous, 5	Enrichment	NKX2-5	2.79
22	Polyposis syndrome, hereditary mixed, 2	Enrichment	BMPR1A	2.79
23	Acromesomelic dysplasia 3	Enrichment	BMPR1B	2.79
24	Brachydactyly, type a1, d	Enrichment	BMPR1B	2.79
25	Frontometaphyseal dysplasia 2	Enrichment	MAP3K7	2.79
26	Atrioventricular septal defect 4	Enrichment	GATA4	2.79
27	Microphthalmia, syndromic 6	Enrichment	BMP4	2.79
28	Orofacial cleft 11	Enrichment	BMP4	2.79
29	Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Enrichment	MEF2C	2.79
30	Atrial septal defect 2	Enrichment	GATA4	2.79
31	Ventricular septal defect 3	Enrichment	NKX2-5	2.79
32	Pulmonary hypertension, primary, 2	Enrichment	SMAD9	2.79
33	Testicular anomalies with or without congenital heart disease	Enrichment	GATA4	2.79
34	Hypoplastic left heart syndrome 2	Enrichment	NKX2-5	2.79
35	20p12.3 microdeletion syndrome	Enrichment	BMP2	2.79
36	8p23.1 microdeletion syndrome	Enrichment	GATA4	2.79
37	Short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies 1	Enrichment	BMP2	2.79
38	Heritable thoracic aortic disease	Enrichment	SMAD4	2.79
39	5q14.3 microdeletion syndrome	Enrichment	MEF2C	2.79
40	Aortic arch interruption	Enrichment	NKX2-5	2.79
41	Primary pulmonary hypertension	Enrichment	BMPR2	2.79
42	Pulmonary hypertension	Enrichment	BMPR2	2.79
43	Complete atrioventricular septal defect without ventricular hypoplasia	Enrichment	MEF2C	2.79
44	Drug- or toxin-induced pulmonary arterial hypertension	Enrichment	BMPR2	2.79
45	Atrial heart septal defect 7	Enrichment	NKX2-5	2.79
46	Partial atrioventricular septal defect with ventricular hypoplasia	Enrichment	GATA4	2.79
47	Mef2c-related disorder	Enrichment	MEF2C	2.79
48	Myhre syndrome	Enrichment	SMAD4	2.49
49	Ebstein anomaly	Enrichment	MYH7	2.49
50	Pulmonary venoocclusive disease 1, autosomal dominant	Enrichment	BMPR2	2.49
51	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	2.49
52	Fibrodysplasia ossificans progressiva	Enrichment	BMPR2	2.49
53	Atrial fibrillation, familial, 6	Enrichment	NPPA	2.49
54	Pulmonary venoocclusive disease 1	Enrichment	BMPR2	2.49
55	Cardiomyopathy, familial hypertrophic, 10	Enrichment	MYL2	2.49
56	46,xy sex reversal 3	Enrichment	GATA4	2.49
57	Myopathy, myofibrillar, 12, infantile-onset, with cardiomyopathy	Enrichment	MYL2	2.49
58	Craniosynostosis 7	Enrichment	BMP2	2.49
59	Hereditary mixed polyposis syndrome	Enrichment	BMPR1A	2.49
60	Familial isolated congenital asplenia	Enrichment	NKX2-5	2.49
61	Deletion 5q35	Enrichment	NKX2-5	2.49
62	Isolated atrial standstill	Enrichment	NPPA	2.49
63	Pulmonary venoocclusive disease	Enrichment	BMPR2	2.49
64	Juvenile polyposis of infancy	Enrichment	BMPR1A	2.49
65	Idiopathic/heritable pulmonary arterial hypertension	Enrichment	BMPR2	2.49
66	Brachydactyly, type a1	Enrichment	BMPR1B	2.31
67	Brachydactyly, type c	Enrichment	BMPR1B	2.31
68	Acromesomelic dysplasia 2a	Enrichment	BMPR1B	2.31
69	Acromesomelic dysplasia 2c	Enrichment	BMPR1B	2.31
70	Acromesomelic dysplasia 2b	Enrichment	BMPR1B	2.31
71	Cardiomyopathy, dilated, 1c, with or without left ventricular noncompaction	Enrichment	MYH7B	2.31
72	Transposition of the great arteries, dextro-looped	Enrichment	BMP2	2.31
73	Atrial standstill 2	Enrichment	NPPA	2.31
74	Frontometaphyseal dysplasia	Enrichment	MAP3K7	2.31
75	Qualitative or quantitative defects of beta-myosin heavy chain	Enrichment	MYH7	2.31
76	Idiopathic camptocormia	Enrichment	MYH7	2.31
77	Myopathy, distal, 1	Enrichment	MYH7	2.19
78	Congenital myopathy 7b, myosin storage, autosomal recessive	Enrichment	MYH7	2.19
79	Microtia-anotia	Enrichment	BMP5	2.19
80	Congenital myopathy 7a, myosin storage, autosomal dominant	Enrichment	MYH7	2.19
81	Hyaline body myopathy	Enrichment	MYH7	2.19
82	Hereditary progressive cardiac conduction defect	Enrichment	NKX2-5	2.19
83	Transposition of the great arteries	Enrichment	GATA4	2.19
84	Congenital myopathy 3 with rigid spine	Enrichment	MYH7	2.09
85	Atrioventricular septal defect	Enrichment	BMP5	2.09
86	Persistent truncus arteriosus	Enrichment	NKX2-5	2.09
87	Atrial septal defect 1	Enrichment	BMP2	2.01
88	Conotruncal heart malformations	Enrichment	NKX2-5	2.01
89	Anterior segment dysgenesis 5	Enrichment	BMP4	2.01
90	Double outlet right ventricle	Enrichment	NKX2-5	2.01
91	Inherited arrhythmogenic cardiomyopathy	Enrichment	MYH7	2.01
92	Hypothyroidism, congenital, nongoitrous, 2	Enrichment	NKX2-5	1.95
93	Gallbladder cancer	Enrichment	SMAD4	1.95
94	Hereditary hemorrhagic telangiectasia	Enrichment	SMAD4	1.95
95	Familial isolated restrictive cardiomyopathy	Enrichment	MYL2	1.95
96	Hemochromatosis, type 1	Enrichment	BMP2	1.89
97	Myocarditis	Enrichment	MYH7	1.89
98	Hypoplastic left heart syndrome	Enrichment	NKX2-5	1.89
99	Tooth agenesis, selective, 1	Enrichment	BMPR2	1.84
100	Cardiomyopathy, familial hypertrophic, 4	Enrichment	MYH7	1.84
101	Familial isolated arrhythmogenic right ventricular dysplasia	Enrichment	MYH7	1.84
102	Peters-plus syndrome	Enrichment	BMP4	1.79
103	Stickler syndrome	Enrichment	BMP4	1.79
104	Atrial heart septal defect	Enrichment	NKX2-5	1.75
105	Interatrial communication	Enrichment	NKX2-5	1.75
106	Familial colorectal cancer type x	Enrichment	BMPR1A	1.75
107	Inherited cancer-predisposing syndrome	Enrichment	BMPR1A, SMAD4	1.72
108	Renal hypodysplasia/aplasia 3	Enrichment	BMP4	1.71
109	Restrictive cardiomyopathy	Enrichment	MYH7	1.71
110	Aortic valve disease 1	Enrichment	NKX2-5	1.68
111	Pulmonary hypertension, primary, 1	Enrichment	BMPR2	1.68
112	Aortic aneurysm, familial thoracic 1	Enrichment	GATA4	1.65
113	Cleft lip/palate	Enrichment	BMP4	1.65
114	46,xy partial gonadal dysgenesis	Enrichment	GATA4	1.65
115	Wolff-parkinson-white syndrome	Enrichment	MYH7	1.59
116	Heart, malformation of	Enrichment	GATA4	1.54
117	Neuromuscular disease	Enrichment	MYH7	1.54
118	Congenital myopathy	Enrichment	MYH7	1.52
119	Pancreatic cancer	Enrichment	SMAD4	1.40
120	Myopathy	Enrichment	MYH7	1.20
121	Gastric cancer	Enrichment	SMAD4	1.17
122	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SMAD4	1.16
123	Thrombocytopenia	Enrichment	SMAD4	1.12
124	Familial isolated dilated cardiomyopathy	Enrichment	MYH7	1.08
125	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	GATA4	1.06
126	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	MEF2C	1.05
127	Colorectal cancer	Enrichment	SMAD4	0.88
128	Ovarian cancer	Enrichment	BMPR1A	0.82
129	Autism spectrum disorder	Enrichment	MEF2C	0.79

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Cardiomyocyte Differentiation through BMP Receptors

Pathway Network for Cardiomyocyte Differentiation through BMP Receptors

Member Pathways for Cardiomyocyte Differentiation through BMP Receptors

Pathways in the Cardiomyocyte Differentiation through BMP Receptors SuperPath

Associated Genes for Cardiomyocyte Differentiation through BMP Receptors

Associated Disorders for Cardiomyocyte Differentiation through BMP Receptors

Disorders associated with Cardiomyocyte Differentiation through BMP Receptors SuperPath

STRING Interaction Network for Cardiomyocyte Differentiation through BMP Receptors

Sources for Cardiomyocyte Differentiation through BMP Receptors