CCL18 signaling pathway

No Pathway Network information available for CCL18 signaling pathway

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

Disorders associated with CCL18 signaling pathway SuperPath

according to GeneCards Suite gene sharing
#DisorderTypeGenesScore
1Human immunodeficiency virus type 1EnrichmentCCL2, CCL3, CCR2, CCR5, IL107.21
2Ehlers-danlos syndrome, arthrochalasia type, 2EnrichmentCOL1A1, COL1A24.43
3Ehlers-danlos/osteogenesis imperfecta syndromeEnrichmentCOL1A1, COL1A24.43
4OsteoporosisEnrichmentCOL1A1, COL1A2, SRC4.12
5High bone mass osteogenesis imperfectaEnrichmentCOL1A1, COL1A23.96
6Arteriovenous malformations of the brainEnrichmentCDH2, IL6, PITPNM33.70
7Ehlers-danlos syndromeEnrichmentCOL1A1, COL1A2, SMAD33.70
8Ehlers-danlos syndrome, arthrochalasia type, 1EnrichmentCOL1A1, COL1A23.66
9Osteogenesis imperfecta with normal sclerae, dominant formEnrichmentCOL1A1, COL1A23.66
10Histiocytoid hemangiomaEnrichmentFOS, VIM3.44
11Ehlers-danlos syndrome, classic type, 1EnrichmentCOL1A1, COL1A23.26
12Osteogenesis imperfecta, type iEnrichmentCOL1A1, COL1A23.26
13Il10-related early-onset inflammatory bowel diseaseEnrichmentIL10, TGFB13.26
14Classic ehlers-danlos syndromeEnrichmentCOL1A1, COL1A23.26
15Prostate cancerEnrichmentCDH1, MAD1L1, PTEN3.14
16Osteogenesis imperfecta, type iiEnrichmentCOL1A1, COL1A23.12
17Thyroid cancer, nonmedullary, 2EnrichmentNRAS, PTEN3.12
18Waardenburg syndrome, type 2eEnrichmentKITLG, SNAI23.12
19Follicular thyroid carcinomaEnrichmentNRAS, PTEN3.12
20Melanocytic nevus syndrome, congenitalEnrichmentNRAS, ZEB23.00
21Primary bone dysplasiaEnrichmentCOL1A1, COL1A22.79
22OsteochondrodysplasiaEnrichmentCOL1A1, COL1A22.71
23Colorectal cancerEnrichmentCDH1, EP300, NRAS, SRC2.70
24Familial thoracic aortic aneurysm and aortic dissectionEnrichmentACTA2, COL1A1, SMAD32.61
25Osteogenesis imperfecta, type ivEnrichmentCOL1A1, COL1A22.56
26Osteogenesis imperfecta, type iiiEnrichmentCOL1A1, COL1A22.43
27Behcet syndromeEnrichmentCCR1, IL102.23
28Ehlers-danlos syndrome, cardiac valvular typeEnrichmentCOL1A22.21
29Cone-rod dystrophy 5EnrichmentPITPNM32.21
30Vacterl association with hydrocephalusEnrichmentPTEN2.21
31Caspase 8 deficiencyEnrichmentCASP82.21
32Hyperpigmentation with or without hypopigmentation, familial progressiveEnrichmentKITLG2.21
33Polycystic lung diseaseEnrichmentCCR22.21
34Melanosis, neurocutaneousEnrichmentNRAS2.21
35Noonan syndrome 6EnrichmentNRAS2.21
36Fetal encasement syndromeEnrichmentCHUK2.21
37Whim syndrome 1EnrichmentCXCR42.21
38Autoimmune lymphoproliferative syndrome, type iiiEnrichmentPRKCD2.21
39Immunodeficiency 15bEnrichmentIKBKB2.21
40Noonan syndrome 13EnrichmentMAPK12.21
41Immunodeficiency 15aEnrichmentIKBKB2.21
42Combined osteogenesis imperfecta and ehlers-danlos syndrome 2EnrichmentCOL1A22.21
43Hereditary lymphedema idEnrichmentVEGFC2.21
44Immune dysregulation, autoimmunity, and autoinflammationEnrichmentPLCG12.21
45Graft-versus-host diseaseEnrichmentIL102.21
46Agenesis of corpus callosum, cardiac, ocular, and genital syndromeEnrichmentCDH22.21
47Lymphatic malformation 4EnrichmentVEGFC2.21
48Papillary tumor of the pineal regionEnrichmentPTEN2.21
49Microvascular complications of diabetes 1EnrichmentVEGFA2.21
50Skin/hair/eye pigmentation, variation in, 7EnrichmentKITLG2.21
51Arrhythmogenic right ventricular dysplasia, familial, 14EnrichmentCDH22.21
52Lactate dehydrogenase b deficiencyEnrichmentLDHB2.21
53Type 1 diabetes mellitus 22EnrichmentCCR52.21
54Glioma susceptibility 2EnrichmentPTEN2.21
55Thrombocytopenia 6EnrichmentSRC2.21
56Bartsocas-papas syndrome 2EnrichmentCHUK2.21
57Asphyxia neonatorumEnrichmentCOL1A12.21
58Deafness, autosomal dominant 69EnrichmentKITLG2.21
59Attention deficit-hyperactivity disorder 8EnrichmentCDH22.21
60Mosaic variegated aneuploidy syndrome 7 with inflammation and tumor predispositionEnrichmentMAD1L12.21
61Breast lobular carcinomaEnrichmentCDH12.21
62Congenital primary lymphedema of gordonEnrichmentVEGFC2.21
63Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiencyEnrichmentCHUK2.21
64Familial progressive hyperpigmentationEnrichmentKITLG2.21
65Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndromeEnrichmentPTEN2.21
66Premature agingEnrichmentVIM2.21
67Familial progressive hyper- and hypopigmentationEnrichmentKITLG2.21
68Neurocutaneous melanocytosisEnrichmentNRAS2.21
69Endometrial cancerEnrichmentCDH1, PTEN2.14
70Brittle bone disorderEnrichmentCOL1A1, COL1A22.07
71Breast cancerEnrichmentCASP8, CDH1, PTEN1.96
72Epiphyseal dysplasia, multiple, 1EnrichmentCOL1A11.91
73Blepharocheilodontic syndrome 1EnrichmentCDH11.91
74Leukocyte adhesion deficiency, type iEnrichmentITGB21.91
75Camurati-engelmann disease 1EnrichmentTGFB11.91
76Spondyloepimetaphyseal dysplasia, strudwick typeEnrichmentFN11.91
77Spondylometaphyseal dysplasia, corner fracture typeEnrichmentFN11.91
78Bruck syndrome 1EnrichmentCOL1A21.91
79Robinow-sorauf syndromeEnrichmentTWIST11.91
80Mowat-wilson syndromeEnrichmentZEB21.91
81Dermatofibrosarcoma protuberansEnrichmentCOL1A11.91
82West nile virusEnrichmentCCR51.91
83Histiocytoma, angiomatoid fibrousEnrichmentCREB11.91
84Aortic aneurysm, familial thoracic 2EnrichmentACTA21.91
85Ectodermal dysplasia and immunodeficiency 2EnrichmentNFKBIA1.91
86Piebald traitEnrichmentSNAI21.91
87Smooth muscle dysfunction syndromeEnrichmentACTA21.91
88Leukocyte adhesion deficiency, type iiiEnrichmentITGB21.91
89Aortic aneurysm, familial thoracic 6EnrichmentACTA21.91
90Ras-associated autoimmune leukoproliferative disorderEnrichmentNRAS1.91
91Moyamoya disease 5EnrichmentACTA21.91
92Loeys-dietz syndrome 3EnrichmentSMAD31.91
93Combined osteogenesis imperfecta and ehlers-danlos syndrome 1EnrichmentCOL1A11.91
94Waardenburg syndrome, type 2fEnrichmentKITLG1.91
95Sweeney-cox syndromeEnrichmentTWIST11.91
96Menke-hennekam syndrome 2EnrichmentEP3001.91
97Inflammatory bowel disease, immunodeficiency, and encephalopathyEnrichmentTGFB11.91
98Cataract 30EnrichmentVIM1.91
99Camurati-engelmann diseaseEnrichmentTGFB11.91
100Stickler syndrome, type iiEnrichmentCOL1A11.91
101Ectodermal dysplasia and immune deficiencyEnrichmentNFKBIA1.91
102Vacterl with hydrocephalusEnrichmentPTEN1.91
103Dentinogenesis imperfectaEnrichmentCOL1A21.91
104Non-syndromic sagittal craniosynostosisEnrichmentTWIST11.91
105Juvenile polyposis of infancyEnrichmentPTEN1.91
106Lung cancerEnrichmentACTA2, CASP81.79
107Connective tissue diseaseEnrichmentACTA2, SMAD31.79
108Craniosynostosis 1EnrichmentTWIST11.74
109Glomerulopathy with fibronectin deposits 2EnrichmentFN11.74
110Multicentric osteolysis, nodulosis, and arthropathyEnrichmentMMP21.74
111Langerhans cell histiocytosisEnrichmentNRAS1.74
112Corneal dystrophy, posterior polymorphous, 3EnrichmentZEB11.74
113Corneal dystrophy, fuchs endothelial, 6EnrichmentZEB11.74
114Hepatitis c virusEnrichmentCCR51.74
115Nasopharyngeal carcinomaEnrichmentNFKBIA1.74
116Caffey diseaseEnrichmentCOL1A11.74
117Large congenital melanocytic nevusEnrichmentNRAS1.74
118Intraocular pressure quantitative trait locusEnrichmentZEB11.74
119Laryngeal squamous cell carcinomaEnrichmentPTEN1.74
120Melanoma of soft tissueEnrichmentCREB11.74
121Kaposi sarcomaEnrichmentIL61.62
122Schimmelpenning-feuerstein-mims syndromeEnrichmentNRAS1.62
123Diffuse gastric and lobular breast cancer syndromeEnrichmentCDH11.62
124PhenylketonuriaEnrichmentCOL1A11.62
125Autoimmune lymphoproliferative syndromeEnrichmentACTA21.62
126Chromosome 22q11.2 deletion syndrome, distalEnrichmentMAPK11.62
127Saethre-chotzen syndromeEnrichmentTWIST11.62
128Congenital generalized lipodystrophyEnrichmentFOS1.62
129Chronic myelogenous leukemia, bcr-abl1 positiveEnrichmentNRAS1.62
130Retinopathy of prematurityEnrichmentFZD41.62
131Aortic aneurysmEnrichmentSMAD31.62
132Corneal dystrophyEnrichmentZEB11.62
133Non-syndromic bicoronal craniosynostosisEnrichmentTWIST11.62
134Systemic-onset juvenile idiopathic arthritisEnrichmentIL61.62
135GliomaEnrichmentPTEN1.62
136Gastric cancerEnrichmentCDH1, PTEN1.55
137Hereditary breast carcinomaEnrichmentCDH1, PTEN1.53
138Exudative vitreoretinopathy 1EnrichmentFZD41.52
139Norrie diseaseEnrichmentFZD41.52
140Macrocephaly/autism syndromeEnrichmentPTEN1.52
141Rheumatoid arthritis, systemic juvenileEnrichmentIL61.52
142Mosaic variegated aneuploidy syndrome 1EnrichmentMAD1L11.52
143Rubinstein-taybi syndrome 2EnrichmentEP3001.52
144Fuchs' endothelial dystrophyEnrichmentZEB11.52
145HemangiomaEnrichmentPTEN1.52
146Persistent hyperplastic primary vitreousEnrichmentFZD41.52
147Acute megakaryocytic leukemiaEnrichmentPTEN1.52
148HemimegalencephalyEnrichmentPTEN1.52
149Diffuse cutaneous systemic sclerosisEnrichmentCCR61.52
150Corneal dystrophy, posterior polymorphous, 1EnrichmentZEB11.44
151Cowden syndrome 1EnrichmentPTEN1.44
152Rubinstein-taybi syndrome 1EnrichmentEP3001.44
153Moyamoya disease 1EnrichmentACTA21.44
154Type 1 diabetes mellitusEnrichmentIL61.44
155Testicular germ cell tumorEnrichmentKITLG1.44
156Chromosome 16p13.3 deletion syndrome, proximalEnrichmentEP3001.44
157Inflammatory bowel disease 25, autosomal recessiveEnrichmentTGFB11.44
158KeratoconusEnrichmentCOL1A11.44
159Limited sclerodermaEnrichmentCCR61.44
160Cleft lip with or without cleft palateEnrichmentCDH11.44
161Nevus, epidermalEnrichmentNRAS1.38
162MyelofibrosisEnrichmentSRC1.38
163Squamous cell carcinoma, head and neckEnrichmentPTEN1.38
164Coats diseaseEnrichmentFZD41.38
165Leukemia, chronic myeloidEnrichmentNRAS1.38
166MegacolonEnrichmentZEB21.38
167Exudative vitreoretinopathyEnrichmentFZD41.32
168Mosaic variegated aneuploidy syndromeEnrichmentMAD1L11.32
169Rheumatoid arthritisEnrichmentIL101.27
170Charge syndromeEnrichmentEP3001.27
171Inflammatory bowel disease 1EnrichmentIL61.27
172Loeys-dietz syndromeEnrichmentSMAD31.27
173Adult hepatocellular carcinomaEnrichmentCASP81.27
174Cowden syndromeEnrichmentPTEN1.27
175Familial thoracic aortic aneurysm and dissectionEnrichmentSMAD31.27
176Cataract 30, multiple typesEnrichmentVIM1.23
177MelanomaEnrichmentPTEN1.23
178Meningioma, familialEnrichmentPTEN1.19
179Lung non-small cell carcinomaEnrichmentNRAS1.19
180Uterine corpus cancerEnrichmentPTEN1.19
181Specific learning disabilityEnrichmentMAPK11.19
182Juvenile myelomonocytic leukemiaEnrichmentNRAS1.15
183MeningiomaEnrichmentPTEN1.15
184Neural tube defectsEnrichmentITGB11.12
185Chromosome 1p36 deletion syndromeEnrichmentPRKCZ1.12
186Protein-deficiency anemiaEnrichmentNRAS1.12
187Aortic aneurysm, familial thoracic 1EnrichmentSMAD31.08
188Lung cancer susceptibility 3EnrichmentACTA21.08
189Cleft lip/palateEnrichmentCDH11.08
190Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variantEnrichmentCDH21.08
191Polydactyly, postaxial, type a1EnrichmentEP3001.06
192Corpus callosum, agenesis ofEnrichmentCDH21.06
193Isolated corpus callosum agenesisEnrichmentCDH21.06
194Rare genetic intellectual disabilityEnrichmentEP3001.06
195Intellectual disability-hypoplastic corpus callosum-preauricular tag syndromeEnrichmentCDH21.06
196Noonan syndrome and noonan-related syndromeEnrichmentNRAS1.06
197RhabdomyosarcomaEnrichmentPTEN1.03
198GliosarcomaEnrichmentNFKBIA1.03
199Giant cell glioblastomaEnrichmentNFKBIA1.00
200Heart, malformation ofEnrichmentMAPK10.98
201Diffuse large b-cell lymphomaEnrichmentPTEN0.96
202Williams-beuren syndromeEnrichmentLIMK10.94
203Hepatocellular carcinomaEnrichmentCASP80.90
204Ovarian cancerEnrichmentCDH1, PTEN0.90
205Noonan syndrome 1EnrichmentNRAS0.88
206Cone dystrophyEnrichmentPITPNM30.86
207Congenital nervous system abnormalityEnrichmentPTEN, ZEB20.86
208Nervous system diseaseEnrichmentPTEN, ZEB20.86
209RasopathyEnrichmentNRAS0.83
210Auditory neuropathyEnrichmentCDH20.83
211Bladder cancerEnrichmentPTEN0.79
212Differentiated thyroid carcinomaEnrichmentNRAS0.79
213MicrocephalyEnrichmentEP300, MAPK10.76
214Cystic fibrosisEnrichmentTGFB10.75
215Severe combined immunodeficiencyEnrichmentIKBKB0.74
216Inherited cancer-predisposing syndromeEnrichmentCDH1, PTEN0.71
217Systemic lupus erythematosusEnrichmentIL100.67
218Leukemia, acute myeloidEnrichmentNRAS0.66
219Type 2 diabetes mellitusEnrichmentIL60.64
220Nephrotic syndromeEnrichmentFN10.63
221ThrombocytopeniaEnrichmentSRC0.59
222HypertelorismEnrichmentCOL1A10.56
223Rare autosomal dominant non-syndromic sensorineural deafness type dfnaEnrichmentKITLG0.56
224Hereditary breast ovarian cancer syndromeEnrichmentPTEN0.54
225Undetermined early-onset epileptic encephalopathyEnrichmentLIMK10.54
226Autosomal recessive non-syndromic intellectual disabilityEnrichmentEZR0.52
227Cone-rod dystrophy 2EnrichmentPITPNM30.47
228Autism spectrum disorderEnrichmentPTEN0.31
229Hereditary retinal dystrophyEnrichmentFZD40.08
230Fundus dystrophyEnrichmentFZD40.08

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