CCR3 Pathway in Eosinophils

No Pathway Network information available for CCR3 Pathway in Eosinophils

Pathways in the CCR3 Pathway in Eosinophils SuperPath

#	Name	Source	Genes
1	CCR3 Pathway in Eosinophils	QIAGEN	ACTA1 ACTA2 ACTB ACTG1 ACTG2 CALM1 CALM2 CALM3 CCL11 CCL24 CCL26 CCR3 CFL1 CFL2 GNA11 GNA12 GNA13 GNA14 GNA15 GNAL GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG2 GNG3 GNG4 HRAS ITPR1 ITPR2 ITPR3 KRAS LIMK1 LIMK2 MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MRAS MYLK NRAS PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 PIK3CG PLA2G4A PLA2G4C PLCB1 PLCB2 PLCB3 PLCB4 PPP1CB PPP1R12A PPP1R12B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 RAC1 RAC2 RAC3 RAF1 RHOA ROCK1 ROCK2 RRAS RRAS2 (see all 87) (see less)
2	VEGF and S-1P Signaling	QIAGEN	ARAF BCAR1 BRAF CALM1 CALM2 CALM3 CRK GNA11 GNA12 GNA13 GNA14 GNA15 GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG2 GNG3 GNG4 HRAS KDR KRAS MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAPK1 MAPK12 MAPK3 MAPK6 MAPK7 MRAS NOS3 NRAS PIK3C2A PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD3 RAF1 RASA1 RRAS RRAS2 S1PR1 SPHK1 SRC VEGFA (see all 58) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CALM1	Calmodulin 1	Protein Coding	2
2	CALM2	Calmodulin 2	Protein Coding	2
3	CALM3	Calmodulin 3	Protein Coding	2
4	GNA11	G Protein Subunit Alpha 11	Protein Coding	2
5	GNA12	G Protein Subunit Alpha 12	Protein Coding	2
6	GNA13	G Protein Subunit Alpha 13	Protein Coding	2
7	GNA14	G Protein Subunit Alpha 14	Protein Coding	2
8	GNA15	G Protein Subunit Alpha 15	Protein Coding	2
9	GNAS	GNAS Complex Locus	Protein Coding	2
10	GNB1	G Protein Subunit Beta 1	Protein Coding	2
11	GNB2	G Protein Subunit Beta 2	Protein Coding	2
12	GNB3	G Protein Subunit Beta 3	Protein Coding	2
13	GNB4	G Protein Subunit Beta 4	Protein Coding	2
14	GNB5	G Protein Subunit Beta 5	Protein Coding	2
15	GNG2	G Protein Subunit Gamma 2	Protein Coding	2
16	GNG3	G Protein Subunit Gamma 3	Protein Coding	2
17	GNG4	G Protein Subunit Gamma 4	Protein Coding	2
18	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	2
19	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	2
20	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	2
21	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	2
22	MAP2K3	Mitogen-Activated Protein Kinase Kinase 3	Protein Coding	2
23	MAP2K4	Mitogen-Activated Protein Kinase Kinase 4	Protein Coding	2
24	MAP2K5	Mitogen-Activated Protein Kinase Kinase 5	Protein Coding	2
25	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	2
26	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	2
27	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	2
28	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	2
29	MRAS	Muscle RAS Oncogene Homolog	Protein Coding	2
30	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	2
31	PRKCA	Protein Kinase C Alpha	Protein Coding	2
32	PRKCB	Protein Kinase C Beta	Protein Coding	2
33	PRKCD	Protein Kinase C Delta	Protein Coding	2
34	PRKCE	Protein Kinase C Epsilon	Protein Coding	2
35	PRKCG	Protein Kinase C Gamma	Protein Coding	2
36	PRKCH	Protein Kinase C Eta	Protein Coding	2
37	PRKCI	Protein Kinase C Iota	Protein Coding	2
38	PRKD1	Protein Kinase D1	Protein Coding	2
39	PRKD3	Protein Kinase D3	Protein Coding	2
40	PRKCQ	Protein Kinase C Theta	Protein Coding	2
41	PRKCZ	Protein Kinase C Zeta	Protein Coding	2
42	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	2
43	RRAS	RAS Related	Protein Coding	2
44	RRAS2	RAS Related 2	Protein Coding	2
45	ACTA1	Actin Alpha 1, Skeletal Muscle	Protein Coding	1
46	ACTA2	Actin Alpha 2, Smooth Muscle	Protein Coding	1
47	ACTB	Actin Beta	Protein Coding	1
48	ACTG1	Actin Gamma 1	Protein Coding	1
49	ACTG2	Actin Gamma 2, Smooth Muscle	Protein Coding	1
50	RHOA	Ras Homolog Family Member A	Protein Coding	1
51	CCL11	C-C Motif Chemokine Ligand 11	Protein Coding	1
52	CCL24	C-C Motif Chemokine Ligand 24	Protein Coding	1
53	CCL26	C-C Motif Chemokine Ligand 26	Protein Coding	1
54	CCR3	C-C Motif Chemokine Receptor 3	Protein Coding	1
55	CFL1	Cofilin 1	Protein Coding	1
56	CFL2	Cofilin 2	Protein Coding	1
57	GNAL	G Protein Subunit Alpha L	Protein Coding	1
58	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	1
59	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	1
60	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	1
61	LIMK1	LIM Domain Kinase 1	Protein Coding	1
62	LIMK2	LIM Domain Kinase 2	Protein Coding	1
63	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	1
64	MAPK13	Mitogen-Activated Protein Kinase 13	Protein Coding	1
65	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
66	MYLK	Myosin Light Chain Kinase	Protein Coding	1
67	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	1
68	PAK2	P21 (RAC1) Activated Kinase 2	Protein Coding	1
69	PAK3	P21 (RAC1) Activated Kinase 3	Protein Coding	1
70	PAK4	P21 (RAC1) Activated Kinase 4	Protein Coding	1
71	PAK6	P21 (RAC1) Activated Kinase 6	Protein Coding	1
72	PAK5	P21 (RAC1) Activated Kinase 5	Protein Coding	1
73	PIK3CG	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma	Protein Coding	1
74	PLA2G4A	Phospholipase A2 Group IVA	Protein Coding	1
75	PLA2G4C	Phospholipase A2 Group IVC	Protein Coding	1
76	PLCB1	Phospholipase C Beta 1	Protein Coding	1
77	PLCB2	Phospholipase C Beta 2	Protein Coding	1
78	PLCB3	Phospholipase C Beta 3	Protein Coding	1
79	PLCB4	Phospholipase C Beta 4	Protein Coding	1
80	PPP1CB	Protein Phosphatase 1 Catalytic Subunit Beta	Protein Coding	1
81	PPP1R12A	Protein Phosphatase 1 Regulatory Subunit 12A	Protein Coding	1
82	PPP1R12B	Protein Phosphatase 1 Regulatory Subunit 12B	Protein Coding	1
83	RAC1	Rac Family Small GTPase 1	Protein Coding	1
84	RAC2	Rac Family Small GTPase 2	Protein Coding	1
85	RAC3	Rac Family Small GTPase 3	Protein Coding	1
86	ROCK1	Rho Associated Coiled-Coil Containing Protein Kinase 1	Protein Coding	1
87	ROCK2	Rho Associated Coiled-Coil Containing Protein Kinase 2	Protein Coding	1
88	ARAF	A-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
89	BCAR1	BCAR1 Scaffold Protein, Cas Family Member	Protein Coding	1
90	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
91	CRK	CRK Proto-Oncogene, Adaptor Protein	Protein Coding	1
92	S1PR1	Sphingosine-1-Phosphate Receptor 1	Protein Coding	1
93	KDR	Kinase Insert Domain Receptor	Protein Coding	1
94	MAPK6	Mitogen-Activated Protein Kinase 6	Protein Coding	1
95	MAPK7	Mitogen-Activated Protein Kinase 7	Protein Coding	1
96	NOS3	Nitric Oxide Synthase 3	Protein Coding	1
97	PIK3C2A	Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha	Protein Coding	1
98	RASA1	RAS P21 Protein Activator 1	Protein Coding	1
99	SPHK1	Sphingosine Kinase 1	Protein Coding	1
100	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
101	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1

Disorders associated with CCR3 Pathway in Eosinophils SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Rasopathy	Enrichment	HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NRAS, PPP1CB, RAF1, RRAS2	16.00
2	Noonan syndrome 1	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, MRAS, NRAS, RAF1, RRAS, RRAS2	16.00
3	Noonan syndrome and noonan-related syndrome	Enrichment	BRAF, HRAS, KRAS, MAP2K1, MAP2K2, NRAS, RAF1	11.33
4	Cardiofaciocutaneous syndrome 1	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	9.53
5	Cardiofaciocutaneous syndrome	Enrichment	BRAF, KRAS, MAP2K1, MAP2K2	9.53
6	Lung non-small cell carcinoma	Enrichment	BRAF, HRAS, KRAS, MAP2K1, NRAS	9.26
7	Melanocytic nevus syndrome, congenital	Enrichment	BRAF, HRAS, NRAS, RAF1	7.68
8	Langerhans cell histiocytosis	Enrichment	BRAF, MAP2K1, NRAS	7.13
9	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	6.53
10	Nevus, epidermal	Enrichment	HRAS, KRAS, NRAS	5.59
11	Thyroid cancer, nonmedullary, 2	Enrichment	BRAF, HRAS, NRAS	5.59
12	Capillary malformation-arteriovenous malformation 1	Enrichment	KRAS, MAP2K1, RASA1	5.59
13	Noonan syndrome 3	Enrichment	HRAS, KRAS, RAF1	5.59
14	Pilomyxoid astrocytoma	Enrichment	BRAF, KRAS, RAF1	5.59
15	Follicular thyroid carcinoma	Enrichment	BRAF, HRAS, NRAS	5.59
16	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	5.39
17	Arteriovenous malformation	Enrichment	HRAS, MAP2K1, RASA1	5.21
18	Differentiated thyroid carcinoma	Enrichment	BRAF, HRAS, KRAS, NRAS	5.18
19	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, MAP2K1, RASA1	5.06
20	Juvenile myelomonocytic leukemia	Enrichment	KRAS, NRAS, RRAS	4.80
21	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	4.75
22	Angioma, tufted	Enrichment	GNA14, KDR	4.75
23	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3, ITPR3	4.42
24	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	4.39
25	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	4.27
26	Anastomosing haemangioma	Enrichment	GNA11, GNA14	4.27
27	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS, NRAS	3.97
28	Noonan syndrome with multiple lentigines	Enrichment	BRAF, RAF1	3.97
29	Capillary malformations, congenital	Enrichment	GNA11, RASA1	3.75
30	Megacystis-microcolon-intestinal hypoperistalsis syndrome 1	Enrichment	ACTG2, MYLK	3.62
31	Hemangioma, capillary infantile	Enrichment	KDR, RASA1	3.57
32	Leukemia, chronic myeloid	Enrichment	KRAS, NRAS	3.43
33	Gallbladder cancer	Enrichment	BRAF, KRAS	3.43
34	Visceral myopathy 1	Enrichment	ACTG2, MYLK	3.40
35	Melanoma, uveal	Enrichment	GNA11, PLCB4	3.22
36	Typical nemaline myopathy	Enrichment	ACTA1, CFL2	3.22
37	Primary hyperaldosteronism	Enrichment	BRAF, GNAS	3.20
38	Stroke, ischemic	Enrichment	NOS3, PRKCH	3.10
39	Non-immune hydrops fetalis	Enrichment	ACTA1, HRAS, KRAS	3.00
40	Microcephaly	Enrichment	ACTB, ACTG1, GNB1, MAPK1, PAK3	2.94
41	Lip and oral cavity carcinoma	Enrichment	BRAF, HRAS	2.94
42	Lung cancer susceptibility 3	Enrichment	BRAF, KRAS	2.80
43	Hypertension, essential	Enrichment	GNB3, NOS3	2.63
44	Arteriovenous malformations of the brain	Enrichment	BRAF, KRAS	2.53
45	Hypocalciuric hypercalcemia, familial, type ii	Enrichment	GNA11	2.37
46	Cystic angiomatosis of bone, diffuse	Enrichment	RASA1	2.37
47	Oculoectodermal syndrome	Enrichment	KRAS	2.37
48	Pallister-killian syndrome	Enrichment	ARAF	2.37
49	Noonan syndrome 5	Enrichment	RAF1	2.37
50	Pseudohypoparathyroidism, type ic	Enrichment	GNAS	2.37
51	Melorheostosis, isolated	Enrichment	MAP2K1	2.37
52	Osseous heteroplasia, progressive	Enrichment	GNAS	2.37
53	Noonan syndrome 7	Enrichment	BRAF	2.37
54	Leopard syndrome 3	Enrichment	BRAF	2.37
55	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.37
56	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.37
57	Melanosis, neurocutaneous	Enrichment	NRAS	2.37
58	Noonan syndrome 6	Enrichment	NRAS	2.37
59	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	2.37
60	Acth-independent macronodular adrenal hyperplasia 1	Enrichment	GNAS	2.37
61	Noonan syndrome 11	Enrichment	MRAS	2.37
62	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	2.37
63	Noonan syndrome 13	Enrichment	MAPK1	2.37
64	Pituitary adenoma 3, multiple types	Enrichment	GNAS	2.37
65	Oculoskeletodental syndrome	Enrichment	PIK3C2A	2.37
66	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	2.37
67	Microvascular complications of diabetes 1	Enrichment	VEGFA	2.37
68	Lymphangioma	Enrichment	BRAF	2.37
69	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	2.37
70	Phace association	Enrichment	BRAF	2.37
71	Spinocerebellar ataxia 14	Enrichment	PRKCG	2.37
72	Melorheostosis	Enrichment	MAP2K1	2.37
73	Leopard syndrome 2	Enrichment	RAF1	2.37
74	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	2.37
75	Long qt syndrome 16	Enrichment	CALM3	2.37
76	Hypocalcemia, autosomal dominant 2	Enrichment	GNA11	2.37
77	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	2.37
78	Disorders of gnas inactivation	Enrichment	GNAS	2.37
79	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	2.37
80	Thrombocytopenia 6	Enrichment	SRC	2.37
81	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	2.37
82	Sick sinus syndrome 4	Enrichment	GNB2	2.37
83	Trigonitis	Enrichment	RAF1	2.37
84	Tufted angioma of skin	Enrichment	KDR	2.37
85	Long qt syndrome 15	Enrichment	CALM2	2.37
86	Congenital pulmonary airway malformation	Enrichment	KRAS	2.37
87	Gorham's disease	Enrichment	RASA1	2.37
88	Syringocystadenoma papilliferum	Enrichment	BRAF	2.37
89	Ganglioglioma	Enrichment	BRAF	2.37
90	Nongerminomatous germ cell tumor	Enrichment	BRAF	2.37
91	Monostotic fibrous dysplasia	Enrichment	GNAS	2.37
92	Phace syndrome	Enrichment	BRAF	2.37
93	Oculocerebrodental syndrome	Enrichment	PIK3C2A	2.37
94	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.37
95	Classic hairy cell leukemia	Enrichment	BRAF	2.37
96	Phakomatosis cesiomarmorata	Enrichment	GNA11	2.37
97	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	2.37
98	Kaposiform hemangioendothelioma	Enrichment	GNA14	2.37
99	Mazabraud syndrome	Enrichment	GNAS	2.37
100	Neurocutaneous melanocytosis	Enrichment	NRAS	2.37
101	Colorectal cancer	Enrichment	BRAF, NRAS, SRC	2.21
102	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	2.19
103	Baraitser-winter syndrome 1	Enrichment	ACTB	2.19
104	Intellectual developmental disorder, x-linked 30	Enrichment	PAK3	2.19
105	Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis	Enrichment	RAC2	2.19
106	Congenital myopathy 2a, typical, autosomal dominant	Enrichment	ACTA1	2.19
107	Myopathy, scapulohumeroperoneal	Enrichment	ACTA1	2.19
108	Megacystis-microcolon-intestinal hypoperistalsis syndrome 5	Enrichment	ACTG2	2.19
109	Spondylometaphyseal dysplasia with corneal dystrophy	Enrichment	PLCB3	2.19
110	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	2.19
111	Knobloch syndrome 2	Enrichment	PAK2	2.19
112	Neurodevelopmental disorder with structural brain anomalies and dysmorphic facies	Enrichment	RAC3	2.19
113	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	2.19
114	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	2.19
115	Auriculocondylar syndrome 2a	Enrichment	PLCB4	2.19
116	Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia	Enrichment	RAC2	2.19
117	Nemaline myopathy 7	Enrichment	CFL2	2.19
118	Becker nevus syndrome	Enrichment	ACTB	2.19
119	Dystonia-deafness syndrome 1	Enrichment	ACTB	2.19
120	Visceral neuropathy, familial, 3, autosomal dominant	Enrichment	ACTG2	2.19
121	Congenital myopathy 2b, severe infantile, autosomal recessive	Enrichment	ACTA1	2.19
122	Cytosolic phospholipase-a2 alpha deficiency associated bleeding disorder	Enrichment	PLA2G4A	2.19
123	Dystonia 25	Enrichment	GNAL	2.19
124	Autosomal dominant familial visceral neuropathy	Enrichment	ACTG2	2.19
125	Immunodeficiency 97 with autoinflammation	Enrichment	PIK3CG	2.19
126	Gastrointestinal ulceration, recurrent, with dysfunctional platelets	Enrichment	PLA2G4A	2.19
127	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	2.19
128	Noonan syndrome-like disorder with loose anagen hair 2	Enrichment	PPP1CB	2.19
129	Congenital myopathy 2c, severe infantile, autosomal dominant	Enrichment	ACTA1	2.19
130	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	2.19
131	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	2.19
132	Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia	Enrichment	RAC2	2.19
133	Auriculocondylar syndrome 2b	Enrichment	PLCB4	2.19
134	Baraitser-winter syndrome	Enrichment	ACTB	2.19
135	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	2.19
136	Zebra body myopathy	Enrichment	ACTA1	2.19
137	Infantile lad-like disease due to rac2 deficiency	Enrichment	RAC2	2.19
138	Congenital smooth muscle hamartoma	Enrichment	ACTB	2.19
139	Reticular dysgenesis-like severe combined immunodeficiency	Enrichment	RAC2	2.19
140	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	2.19
141	Cryptogenic multifocal ulcerous stenosing enteritis	Enrichment	PLA2G4A	2.19
142	Actin-accumulation myopathy	Enrichment	ACTA1	2.19
143	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.19
144	Myopathic intestinal pseudoobstruction	Enrichment	ACTG2	2.19
145	Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome	Enrichment	RAC2	2.19
146	Actg2 visceral myopathy	Enrichment	ACTG2	2.19
147	Bladder cancer	Enrichment	HRAS, KRAS	2.17
148	Long qt syndrome	Enrichment	CALM1, CALM2	2.11
149	Centronuclear myopathy	Enrichment	ACTA1, CFL2	2.10
150	Lung cancer	Enrichment	BRAF, KRAS	2.09
151	Pseudohypoparathyroidism, type ia	Enrichment	GNAS	2.07
152	Scoliosis, isolated 1	Enrichment	MAPK7	2.07
153	Costello syndrome	Enrichment	HRAS	2.07
154	Cutis marmorata telangiectatica congenita	Enrichment	GNA11	2.07
155	Pulmonic stenosis	Enrichment	BRAF	2.07
156	Pigmented nodular adrenocortical disease, primary, 1	Enrichment	GNAS	2.07
157	Pseudopseudohypoparathyroidism	Enrichment	GNAS	2.07
158	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	2.07
159	Encephalocraniocutaneous lipomatosis	Enrichment	KRAS	2.07
160	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	2.07
161	Long qt syndrome 14	Enrichment	CALM1	2.07
162	Noonan syndrome 12	Enrichment	RRAS2	2.07
163	Autosomal dominant hypocalcemia	Enrichment	GNA11	2.07
164	Pseudohypoparathyroidism	Enrichment	GNAS	2.07
165	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	2.07
166	Acth-independent macronodular adrenal hyperplasia	Enrichment	GNAS	2.07
167	Tafro syndrome	Enrichment	MAP2K2	2.07
168	Cerebral visual impairment	Enrichment	GNB1	2.07
169	Phakomatosis cesioflammea	Enrichment	GNA11	2.07
170	Wooly hair nevus	Enrichment	HRAS	2.07
171	Hydrops fetalis, nonimmune	Enrichment	ACTA1, HRAS	1.92
172	Leukemia, acute myeloid	Enrichment	KRAS, NRAS	1.90
173	Mccune-albright syndrome	Enrichment	GNAS	1.89
174	Ataxia-telangiectasia	Enrichment	BRAF	1.89
175	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	GNA11	1.89
176	Tethered spinal cord syndrome	Enrichment	BRAF	1.89
177	Wieacker-wolff syndrome	Enrichment	RASA1	1.89
178	Spermatocytoma	Enrichment	HRAS	1.89
179	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	GNAS	1.89
180	Spinocerebellar ataxia 29	Enrichment	ITPR1	1.89
181	Aortic aneurysm, familial thoracic 2	Enrichment	ACTA2	1.89
182	Deafness, autosomal dominant 20	Enrichment	ACTG1	1.89
183	Smooth muscle dysfunction syndrome	Enrichment	ACTA2	1.89
184	Aortic aneurysm, familial thoracic 6	Enrichment	ACTA2	1.89
185	Baraitser-winter syndrome 2	Enrichment	ACTG1	1.89
186	Moyamoya disease 5	Enrichment	ACTA2	1.89
187	Genitourinary and/or brain malformation syndrome	Enrichment	PPP1R12A	1.89
188	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	1.89
189	Noonan syndrome-like disorder with loose anagen hair	Enrichment	PPP1CB	1.89
190	Ocular melanoma	Enrichment	PLCB4	1.89
191	Intestinal obstruction	Enrichment	ACTG2	1.89
192	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	1.77
193	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	1.77
194	Thyroid cancer, nonmedullary, 1	Enrichment	BRAF	1.77
195	Pseudohypoparathyroidism, type ib	Enrichment	GNAS	1.77
196	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.77
197	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	1.77
198	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.77
199	Lung sarcomatoid carcinoma	Enrichment	KRAS	1.77
200	Hereditary ataxia	Enrichment	PRKCG	1.77
201	Craniopharyngioma	Enrichment	BRAF	1.77
202	Pilocytic astrocytoma	Enrichment	KRAS	1.77
203	Newborn respiratory distress syndrome	Enrichment	BRAF	1.77
204	Epidermolytic nevus	Enrichment	HRAS	1.77
205	Familial sick sinus syndrome	Enrichment	GNB2	1.77
206	Gillespie syndrome	Enrichment	ITPR1	1.72
207	Aortic aneurysm, familial thoracic 7	Enrichment	MYLK	1.72
208	Dystonia	Enrichment	GNAL, GNB1	1.68
209	Alzheimer disease 2	Enrichment	NOS3	1.67
210	Pre-eclampsia	Enrichment	NOS3	1.67
211	Hereditary breast ovarian cancer syndrome	Enrichment	BCAR1, KRAS	1.64
212	Myeloma, multiple	Enrichment	BRAF, KRAS	1.62
213	Klippel-trenaunay-weber syndrome	Enrichment	RASA1	1.60
214	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	RASA1	1.60
215	Wilms tumor 5	Enrichment	BRAF	1.60
216	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	1.60
217	Basal cell carcinoma 1	Enrichment	RASA1	1.60
218	Breast adenocarcinoma	Enrichment	KRAS	1.60
219	Lung squamous cell carcinoma	Enrichment	KRAS	1.60
220	Nemaline myopathy 2	Enrichment	ACTA1	1.59
221	Autoimmune lymphoproliferative syndrome	Enrichment	ACTA2	1.59
222	Auriculocondylar syndrome 1	Enrichment	PLCB4	1.59
223	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.59
224	Aminoacylase 1 deficiency	Enrichment	ACTB	1.59
225	Developmental and epileptic encephalopathy 12	Enrichment	PLCB1	1.59
226	Knobloch syndrome	Enrichment	PAK2	1.59
227	Intermediate nemaline myopathy	Enrichment	ACTA1	1.59
228	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.59
229	Primary ovarian insufficiency	Enrichment	KDR, NOS3	1.58
230	Myelofibrosis	Enrichment	SRC	1.53
231	Brachydactyly	Enrichment	GNAS	1.53
232	Hereditary hemorrhagic telangiectasia	Enrichment	RASA1	1.53
233	Congenital myopathy 3 with rigid spine	Enrichment	ACTA1	1.50
234	Knobloch syndrome 1	Enrichment	PAK2	1.50
235	Mosaic variegated aneuploidy syndrome 1	Enrichment	PAK6	1.50
236	Coloboma of choroid and retina	Enrichment	ACTG1	1.50
237	Severe congenital nemaline myopathy	Enrichment	ACTA1	1.50
238	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	ACTA2, MYLK	1.49
239	Spastic paraplegia 4, autosomal dominant	Enrichment	GNAS	1.47
240	Lymphoma, non-hodgkin, familial	Enrichment	BRAF	1.47
241	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	1.47
242	Hypothyroidism	Enrichment	GNB1	1.47
243	Cardiomyopathy, familial hypertrophic, 4	Enrichment	BRAF	1.42
244	Inflammatory bowel disease 1	Enrichment	PRKCQ	1.42
245	Ventricular septal defect	Enrichment	BRAF	1.42
246	Hemihyperplasia, isolated	Enrichment	RHOA	1.42
247	Moyamoya disease 1	Enrichment	ACTA2	1.42
248	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	1.42
249	Intestinal pseudo-obstruction	Enrichment	ACTG2	1.42
250	Breast cancer	Enrichment	GNG3, KRAS	1.39
251	Melanoma	Enrichment	BRAF	1.38
252	Childhood-onset nemaline myopathy	Enrichment	ACTA1	1.36
253	Complex neurodevelopmental disorder	Enrichment	GNB2, PAK3, RAC3	1.34
254	Dilated cardiomyopathy	Enrichment	BRAF, RAF1	1.34
255	Leukemia, acute lymphoblastic	Enrichment	GNB1	1.34
256	Myelodysplastic syndrome	Enrichment	GNB1	1.34
257	Specific learning disability	Enrichment	MAPK1	1.34
258	Mosaic variegated aneuploidy syndrome	Enrichment	PAK6	1.30
259	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	1.27
260	Protein-deficiency anemia	Enrichment	NRAS	1.27
261	Developmental and epileptic encephalopathy 14	Enrichment	PLCB1	1.25
262	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	1.25
263	Familial thoracic aortic aneurysm and dissection	Enrichment	MYLK	1.25
264	Osteoporosis	Enrichment	SRC	1.23
265	Wilms tumor 1	Enrichment	BRAF	1.21
266	Lynch syndrome	Enrichment	KRAS	1.21
267	Cat eye syndrome	Enrichment	ACTG1	1.21
268	Nemaline myopathy	Enrichment	ACTA1	1.21
269	Rhabdomyosarcoma	Enrichment	HRAS	1.18
270	Asthma	Enrichment	CCL11	1.17
271	Ovarian cancer	Enrichment	KRAS, RRAS2	1.16
272	Alzheimer disease, familial, 1	Enrichment	NOS3	1.15
273	Melanoma, cutaneous malignant 1	Enrichment	BRAF	1.15
274	Cleft palate, isolated	Enrichment	GNB1	1.15
275	Dandy-walker syndrome	Enrichment	BRAF	1.15
276	Sudden infant death syndrome	Enrichment	CALM2	1.15
277	Heart, malformation of	Enrichment	MAPK1	1.13
278	Congenital long qt syndrome	Enrichment	ITPR3	1.13
279	Diffuse large b-cell lymphoma	Enrichment	BRAF	1.11
280	Autism spectrum disorder	Enrichment	GNB1, MAP2K1	1.10
281	Multiple sclerosis	Enrichment	ITPR1	1.06
282	Aortic aneurysm, familial thoracic 1	Enrichment	MYLK	1.06
283	Attention deficit-hyperactivity disorder	Enrichment	GNB5	1.05
284	Congenital myopathy 4a, autosomal dominant	Enrichment	ACTA1	1.04
285	Anterior segment dysgenesis	Enrichment	ITPR1	1.04
286	Congenital stationary night blindness	Enrichment	GNB3	1.03
287	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	1.01
288	Pancreatic cancer	Enrichment	KRAS	0.99
289	Tetralogy of fallot	Enrichment	KDR	0.98
290	Strabismus	Enrichment	GNB1	0.96
291	Human immunodeficiency virus type 1	Enrichment	CCL11	0.96
292	Neuromuscular disease	Enrichment	ACTA1	0.96
293	Congenital myopathy	Enrichment	ACTA1	0.94
294	Williams-beuren syndrome	Enrichment	LIMK1	0.92
295	Lissencephaly	Enrichment	ACTG1	0.90
296	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.88
297	Left ventricular noncompaction	Enrichment	RAF1	0.86
298	Cerebral palsy	Enrichment	GNB1	0.81
299	Gastric cancer	Enrichment	KRAS	0.77
300	Hereditary breast carcinoma	Enrichment	KRAS	0.76
301	Thrombocytopenia	Enrichment	SRC	0.73
302	Connective tissue disease	Enrichment	ACTA2	0.73
303	Body mass index quantitative trait locus 11	Enrichment	GNAS	0.71
304	Autosomal dominant non-syndromic intellectual disability	Enrichment	GNB1	0.71
305	Cakut	Enrichment	ACTG1	0.71
306	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.69
307	Non-syndromic genetic deafness	Enrichment	ACTG1	0.68
308	Fetal akinesia deformation sequence 1	Enrichment	ACTA1	0.67
309	Myopathy	Enrichment	ACTA1	0.64
310	Benign epilepsy with centrotemporal spikes	Enrichment	PLCB1	0.63
311	Distal arthrogryposis	Enrichment	ACTA1	0.63
312	Nonsyndromic hearing loss	Enrichment	ACTG1	0.63
313	Centralopathic epilepsy	Enrichment	PLCB1	0.62
314	West syndrome	Enrichment	PLCB1	0.61
315	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ACTG1	0.55
316	Spastic ataxia	Enrichment	ITPR1	0.54
317	Undetermined early-onset epileptic encephalopathy	Enrichment	LIMK1	0.52
318	Congenital nervous system abnormality	Enrichment	GNB5	0.44
319	Nervous system disease	Enrichment	GNB5	0.44
320	Rare genetic deafness	Enrichment	ACTG1	0.40

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

CCR3 Pathway in Eosinophils

Pathway Network for CCR3 Pathway in Eosinophils

Member Pathways for CCR3 Pathway in Eosinophils

Pathways in the CCR3 Pathway in Eosinophils SuperPath

Associated Genes for CCR3 Pathway in Eosinophils

Associated Disorders for CCR3 Pathway in Eosinophils

Disorders associated with CCR3 Pathway in Eosinophils SuperPath

STRING Interaction Network for CCR3 Pathway in Eosinophils

Sources for CCR3 Pathway in Eosinophils