CD209 (DC-SIGN) signaling

No Pathway Network information available for CD209 (DC-SIGN) signaling

Pathways in the CD209 (DC-SIGN) signaling SuperPath

#	Name	Source	Genes
1	CD209 (DC-SIGN) signaling	Reactome	CD209 CREBBP EP300 FYN HRAS ICAM2 ICAM3 KRAS LYN NFKB1 NRAS PAK1 PAK2 PAK3 PRKACA PRKACB PRKACG RAF1 RELA RELB RPS6KA5 (see all 21) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
2	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
3	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
4	CD209	CD209 Molecule	Protein Coding	1
5	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	1
6	ICAM2	Intercellular Adhesion Molecule 2	Protein Coding	1
7	ICAM3	Intercellular Adhesion Molecule 3	Protein Coding	1
8	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	1
9	LYN	LYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
10	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
11	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	1
12	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	1
13	PAK2	P21 (RAC1) Activated Kinase 2	Protein Coding	1
14	PAK3	P21 (RAC1) Activated Kinase 3	Protein Coding	1
15	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
16	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	1
17	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	1
18	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
19	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	1
20	RELB	RELB Proto-Oncogene, NF-KB Subunit	Protein Coding	1
21	RPS6KA5	Ribosomal Protein S6 Kinase A5	Protein Coding	1

Disorders associated with CD209 (DC-SIGN) signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, KRAS, NRAS, RAF1	8.24
2	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	7.89
3	Noonan syndrome 1	Enrichment	HRAS, KRAS, NRAS, RAF1	7.43
4	Rasopathy	Enrichment	HRAS, KRAS, NRAS, RAF1	7.21
5	Nevus, epidermal	Enrichment	HRAS, KRAS, NRAS	6.95
6	Noonan syndrome 3	Enrichment	HRAS, KRAS, RAF1	6.95
7	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, NRAS, RAF1	6.75
8	Lung non-small cell carcinoma	Enrichment	HRAS, KRAS, NRAS	6.28
9	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	5.64
10	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	5.16
11	Differentiated thyroid carcinoma	Enrichment	HRAS, KRAS, NRAS	4.94
12	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS, NRAS	4.86
13	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	4.47
14	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	4.47
15	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS, NRAS	4.32
16	Leukemia, chronic myeloid	Enrichment	KRAS, NRAS	4.32
17	Pilomyxoid astrocytoma	Enrichment	KRAS, RAF1	4.32
18	Follicular thyroid carcinoma	Enrichment	HRAS, NRAS	4.32
19	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	4.09
20	Juvenile myelomonocytic leukemia	Enrichment	KRAS, NRAS	3.83
21	Rare genetic intellectual disability	Enrichment	CREBBP, EP300	3.63
22	Bladder cancer	Enrichment	HRAS, KRAS	3.04
23	Non-immune hydrops fetalis	Enrichment	HRAS, KRAS	2.99
24	Oculoectodermal syndrome	Enrichment	KRAS	2.81
25	Intellectual developmental disorder, x-linked 30	Enrichment	PAK3	2.81
26	Noonan syndrome 5	Enrichment	RAF1	2.81
27	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.81
28	Melanosis, neurocutaneous	Enrichment	NRAS	2.81
29	Noonan syndrome 6	Enrichment	NRAS	2.81
30	Knobloch syndrome 2	Enrichment	PAK2	2.81
31	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	2.81
32	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	2.81
33	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	2.81
34	Leopard syndrome 2	Enrichment	RAF1	2.81
35	Dengue virus	Enrichment	CD209	2.81
36	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	2.81
37	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	2.81
38	Immunodeficiency 53	Enrichment	RELB	2.81
39	Autoinflammatory disease, systemic, with vasculitis	Enrichment	LYN	2.81
40	Menke-hennekam syndrome 1	Enrichment	CREBBP	2.81
41	Trigonitis	Enrichment	RAF1	2.81
42	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	2.81
43	Congenital pulmonary airway malformation	Enrichment	KRAS	2.81
44	Menke-hennekam syndrome	Enrichment	CREBBP	2.81
45	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.81
46	Neurocutaneous melanocytosis	Enrichment	NRAS	2.81
47	Leukemia, acute myeloid	Enrichment	KRAS, NRAS	2.76
48	Costello syndrome	Enrichment	HRAS	2.51
49	Thumb deformity	Enrichment	CREBBP	2.51
50	Encephalocraniocutaneous lipomatosis	Enrichment	KRAS	2.51
51	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	2.51
52	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.51
53	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	2.51
54	Menke-hennekam syndrome 2	Enrichment	EP300	2.51
55	Rela fusion-positive ependymoma	Enrichment	RELA	2.51
56	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	2.51
57	Fibrolamellar carcinoma	Enrichment	PRKACA	2.51
58	Common variable immunodeficiency 12	Enrichment	NFKB1	2.51
59	Wooly hair nevus	Enrichment	HRAS	2.51
60	Myeloma, multiple	Enrichment	CREBBP, KRAS	2.48
61	Langerhans cell histiocytosis	Enrichment	NRAS	2.33
62	Tethered spinal cord syndrome	Enrichment	CREBBP	2.33
63	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	2.33
64	Spermatocytoma	Enrichment	HRAS	2.33
65	Cardiofaciocutaneous syndrome 1	Enrichment	KRAS	2.21
66	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	2.21
67	Cardiofaciocutaneous syndrome	Enrichment	KRAS	2.21
68	Lung sarcomatoid carcinoma	Enrichment	KRAS	2.21
69	Noonan syndrome with multiple lentigines	Enrichment	RAF1	2.21
70	Pilocytic astrocytoma	Enrichment	KRAS	2.21
71	Epidermolytic nevus	Enrichment	HRAS	2.21
72	Knobloch syndrome	Enrichment	PAK2	2.21
73	Knobloch syndrome 1	Enrichment	PAK2	2.11
74	Rubinstein-taybi syndrome 2	Enrichment	EP300	2.11
75	Colorectal cancer	Enrichment	EP300, NRAS	2.10
76	Breast adenocarcinoma	Enrichment	KRAS	2.03
77	Lung squamous cell carcinoma	Enrichment	KRAS	2.03
78	Hypertrichosis	Enrichment	CREBBP	2.03
79	Capillary malformation-arteriovenous malformation 1	Enrichment	KRAS	1.97
80	Gallbladder cancer	Enrichment	KRAS	1.97
81	Common variable immunodeficiency	Enrichment	NFKB1	1.97
82	Charge syndrome	Enrichment	EP300	1.86
83	Arteriovenous malformation	Enrichment	HRAS	1.86
84	Microcephaly	Enrichment	EP300, PAK3	1.82
85	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS	1.81
86	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.81
87	Lip and oral cavity carcinoma	Enrichment	HRAS	1.73
88	Protein-deficiency anemia	Enrichment	NRAS	1.70
89	Lung cancer susceptibility 3	Enrichment	KRAS	1.67
90	Heart disease	Enrichment	CREBBP	1.67
91	Polydactyly, postaxial, type a1	Enrichment	EP300	1.64
92	Corpus callosum, agenesis of	Enrichment	CREBBP	1.64
93	Lynch syndrome	Enrichment	KRAS	1.64
94	Isolated corpus callosum agenesis	Enrichment	CREBBP	1.64
95	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP	1.64
96	Rhabdomyosarcoma	Enrichment	HRAS	1.61
97	Human immunodeficiency virus type 1	Enrichment	CD209	1.56
98	Arteriovenous malformations of the brain	Enrichment	KRAS	1.54
99	Diffuse large b-cell lymphoma	Enrichment	CREBBP	1.54
100	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	1.44
101	Scoliosis	Enrichment	CREBBP	1.44
102	Pancreatic cancer	Enrichment	KRAS	1.42
103	Hydrops fetalis, nonimmune	Enrichment	HRAS	1.40
104	Lung cancer	Enrichment	KRAS	1.31
105	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	1.30
106	Left ventricular noncompaction	Enrichment	RAF1	1.28
107	Gastric cancer	Enrichment	KRAS	1.19
108	Hereditary breast carcinoma	Enrichment	KRAS	1.18
109	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	1.10
110	Hereditary breast ovarian cancer syndrome	Enrichment	KRAS	1.09
111	Autism	Enrichment	CREBBP	0.98
112	Breast cancer	Enrichment	KRAS	0.96
113	Dilated cardiomyopathy	Enrichment	RAF1	0.93
114	Ovarian cancer	Enrichment	KRAS	0.84
115	Congenital nervous system abnormality	Enrichment	CREBBP	0.82
116	Nervous system disease	Enrichment	CREBBP	0.82
117	Complex neurodevelopmental disorder	Enrichment	PAK3	0.76

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

CD209 (DC-SIGN) signaling

Pathway Network for CD209 (DC-SIGN) signaling

Member Pathways for CD209 (DC-SIGN) signaling

Pathways in the CD209 (DC-SIGN) signaling SuperPath

Associated Genes for CD209 (DC-SIGN) signaling

Associated Disorders for CD209 (DC-SIGN) signaling

Disorders associated with CD209 (DC-SIGN) signaling SuperPath

STRING Interaction Network for CD209 (DC-SIGN) signaling

Sources for CD209 (DC-SIGN) signaling