Cell cycle_Role of APC in cell cycle regulation

No Pathway Network information available for Cell cycle_Role of APC in cell cycle regulation

Pathways in the Cell cycle_Role of APC in cell cycle regulation SuperPath

#	Name	Source	Genes
1	Cell cycle_Role of APC in cell cycle regulation	GeneGo (Thomson Reuters)	ANAPC1 ANAPC10 ANAPC11 ANAPC13 ANAPC2 ANAPC4 ANAPC5 ANAPC7 AURKA AURKB BUB1 BUB1B BUB3 CCNA1 CCNA2 CCNB1 CCNB2 CCNB3 CCT2 CCT3 CCT4 CCT5 CCT6A CCT6B CCT7 CCT8 CDC14A CDC16 CDC20 CDC23 CDC25A CDC26 CDC27 CDC6 CDCA3 CDK1 CDK2 CKS1B FBXO5 FZR1 GMNN KIF22 MAD2L1 MAD2L2 NEK2 ORC1 PLK1 PRKACA PRKACB PRKACG PTTG1 RASSF1 SKP2 TCP1 (see all 54) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	BUB1	BUB1 Mitotic Checkpoint Serine/Threonine Kinase	Protein Coding	1
2	BUB1B	BUB1 Mitotic Checkpoint Serine/Threonine Kinase B	Protein Coding	1
3	CCNA2	Cyclin A2	Protein Coding	1
4	CCNB1	Cyclin B1	Protein Coding	1
5	CCT6A	Chaperonin Containing TCP1 Subunit 6A	Protein Coding	1
6	CDK1	Cyclin Dependent Kinase 1	Protein Coding	1
7	CDC6	Cell Division Cycle 6	Protein Coding	1
8	CDC20	Cell Division Cycle 20	Protein Coding	1
9	CDC25A	Cell Division Cycle 25A	Protein Coding	1
10	CDC27	Cell Division Cycle 27	Protein Coding	1
11	CDK2	Cyclin Dependent Kinase 2	Protein Coding	1
12	CKS1B	CDC28 Protein Kinase Regulatory Subunit 1B	Protein Coding	1
13	KIF22	Kinesin Family Member 22	Protein Coding	1
14	MAD2L1	Mitotic Arrest Deficient 2 Like 1	Protein Coding	1
15	NEK2	NIMA Related Kinase 2	Protein Coding	1
16	ORC1	Origin Recognition Complex Subunit 1	Protein Coding	1
17	PLK1	Polo Like Kinase 1	Protein Coding	1
18	PRKACA	Protein Kinase CAMP-Activated Catalytic Subunit Alpha	Protein Coding	1
19	PRKACB	Protein Kinase CAMP-Activated Catalytic Subunit Beta	Protein Coding	1
20	PRKACG	Protein Kinase CAMP-Activated Catalytic Subunit Gamma	Protein Coding	1
21	SKP2	S-Phase Kinase Associated Protein 2	Protein Coding	1
22	AURKA	Aurora Kinase A	Protein Coding	1
23	TCP1	T-Complex 1	Protein Coding	1
24	CCT3	Chaperonin Containing TCP1 Subunit 3	Protein Coding	1
25	CDC14A	Cell Division Cycle 14A	Protein Coding	1
26	CDC23	Cell Division Cycle 23	Protein Coding	1
27	CDC16	Cell Division Cycle 16	Protein Coding	1
28	CCNA1	Cyclin A1	Protein Coding	1
29	CCNB2	Cyclin B2	Protein Coding	1
30	BUB3	BUB3 Mitotic Checkpoint Protein	Protein Coding	1
31	AURKB	Aurora Kinase B	Protein Coding	1
32	PTTG1	PTTG1 Regulator Of Sister Chromatid Separation, Securin	Protein Coding	1
33	ANAPC10	Anaphase Promoting Complex Subunit 10	Protein Coding	1
34	MAD2L2	Mitotic Arrest Deficient 2 Like 2	Protein Coding	1
35	CCT7	Chaperonin Containing TCP1 Subunit 7	Protein Coding	1
36	CCT4	Chaperonin Containing TCP1 Subunit 4	Protein Coding	1
37	CCT2	Chaperonin Containing TCP1 Subunit 2	Protein Coding	1
38	CCT6B	Chaperonin Containing TCP1 Subunit 6B	Protein Coding	1
39	CCT8	Chaperonin Containing TCP1 Subunit 8	Protein Coding	1
40	RASSF1	Ras Association Domain Family Member 1	Protein Coding	1
41	CCT5	Chaperonin Containing TCP1 Subunit 5	Protein Coding	1
42	ANAPC13	Anaphase Promoting Complex Subunit 13	Protein Coding	1
43	FBXO5	F-Box Protein 5	Protein Coding	1
44	ANAPC2	Anaphase Promoting Complex Subunit 2	Protein Coding	1
45	ANAPC4	Anaphase Promoting Complex Subunit 4	Protein Coding	1
46	GMNN	Geminin DNA Replication Inhibitor	Protein Coding	1
47	FZR1	Fizzy And Cell Division Cycle 20 Related 1	Protein Coding	1
48	ANAPC5	Anaphase Promoting Complex Subunit 5	Protein Coding	1
49	ANAPC7	Anaphase Promoting Complex Subunit 7	Protein Coding	1
50	ANAPC11	Anaphase Promoting Complex Subunit 11	Protein Coding	1
51	ANAPC1	Anaphase Promoting Complex Subunit 1	Protein Coding	1
52	CDCA3	Cell Division Cycle Associated 3	Protein Coding	1
53	CCNB3	Cyclin B3	Protein Coding	1
54	CDC26	Cell Division Cycle 26	Protein Coding	1

Disorders associated with Cell cycle_Role of APC in cell cycle regulation SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Mosaic variegated aneuploidy syndrome	Enrichment	BUB1, BUB1B, BUB3	5.48
2	Meier-gorlin syndrome 1	Enrichment	CDC6, GMNN, ORC1	5.15
3	Ellis-van creveld syndrome	Enrichment	PRKACA, PRKACB	3.26
4	Deafness, autosomal recessive 32, with or without immotile sperm	Enrichment	CDC14A	2.40
5	Premature chromatid separation trait	Enrichment	BUB1B	2.40
6	Fanconi anemia, complementation group v	Enrichment	MAD2L2	2.40
7	Oocyte/zygote/embryo maturation arrest 14	Enrichment	CDC20	2.40
8	Intellectual developmental disorder with polymicrogyria and seizures	Enrichment	TCP1	2.40
9	Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive	Enrichment	CCT5	2.40
10	Cardioacrofacial dysplasia 2	Enrichment	PRKACB	2.40
11	Ferguson-bonni neurodevelopmental syndrome	Enrichment	ANAPC7	2.40
12	Developmental and epileptic encephalopathy 109	Enrichment	FZR1	2.40
13	Autosomal recessive sensory neuropathy with spastic paraplegia	Enrichment	CCT5	2.40
14	Spondyloepimetaphyseal dysplasia with joint laxity, type 2	Enrichment	KIF22	2.40
15	Rothmund-thomson syndrome, type 1	Enrichment	ANAPC1	2.40
16	Retinitis pigmentosa 67	Enrichment	NEK2	2.40
17	Pigmented nodular adrenocortical disease, primary, 4	Enrichment	PRKACA	2.40
18	Meier-gorlin syndrome 5	Enrichment	CDC6	2.40
19	Cardioacrofacial dysplasia 1	Enrichment	PRKACA	2.40
20	Meier-gorlin syndrome 6	Enrichment	GMNN	2.40
21	Autosomal recessive nonsyndromic deafness 32	Enrichment	CDC14A	2.40
22	Microcephaly 30, primary, autosomal recessive	Enrichment	BUB1	2.40
23	Neurodevelopmental disorder with speech or visual impairment and brain hypomyelination	Enrichment	CCT3	2.40
24	Colorectal cancer	Enrichment	AURKA, BUB1, BUB1B	2.30
25	Bleeding disorder, platelet-type, 19	Enrichment	PRKACG	2.10
26	Night blindness, congenital stationary, type 1h	Enrichment	CDCA3	2.10
27	Fibrolamellar carcinoma	Enrichment	PRKACA	2.10
28	Ciliary dyskinesia, primary, 22	Enrichment	RASSF1	1.80
29	Pregnancy loss, recurrent 1	Enrichment	CCNB3	1.80
30	Mosaic variegated aneuploidy syndrome 1	Enrichment	BUB1B	1.70
31	Nk-cell enteropathy	Enrichment	AURKB	1.30
32	Hypertension, essential	Enrichment	CDCA3	1.18
33	Polycystic liver disease	Enrichment	CDC25A	1.18
34	Autosomal dominant polycystic liver disease	Enrichment	CDC25A	1.18
35	Myocardial infarction	Enrichment	CCT7	1.08
36	Ear malformation	Enrichment	CDC14A	1.04
37	Fanconi anemia, complementation group a	Enrichment	MAD2L2	0.88
38	Sensorineural hearing loss	Enrichment	CDC14A	0.76
39	Myeloma, multiple	Enrichment	AURKA	0.70
40	Undetermined early-onset epileptic encephalopathy	Enrichment	FZR1	0.70
41	Breast cancer	Enrichment	CKS1B	0.59
42	Rare genetic deafness	Enrichment	CDC14A	0.57
43	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	CDC14A	0.52
44	Leber plus disease	Enrichment	CCT2	0.50
45	Ovarian cancer	Enrichment	BUB1B	0.48
46	Retinitis pigmentosa	Enrichment	NEK2	0.24
47	Hereditary retinal dystrophy	Enrichment	NEK2	0.16
48	Fundus dystrophy	Enrichment	NEK2	0.16

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Cell cycle_Role of APC in cell cycle regulation

Pathway Network for Cell cycle_Role of APC in cell cycle regulation

Member Pathways for Cell cycle_Role of APC in cell cycle regulation

Pathways in the Cell cycle_Role of APC in cell cycle regulation SuperPath

Associated Genes for Cell cycle_Role of APC in cell cycle regulation

Associated Disorders for Cell cycle_Role of APC in cell cycle regulation

Disorders associated with Cell cycle_Role of APC in cell cycle regulation SuperPath

STRING Interaction Network for Cell cycle_Role of APC in cell cycle regulation

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