Cell differentiation - expanded index

No Pathway Network information available for Cell differentiation - expanded index

Pathways in the Cell differentiation - expanded index SuperPath

#	Name	Source	Genes
1	Cell differentiation - expanded index	WikiPathways	EZH2 HDAC5 ID2 KLF4 LEFTY1 LEFTY2 MEF2A MEF2B MEF2C MEF2D MIR1-1 MIR106A MIR128-1 MIR133A1 MIR133A2 MIR133B MIR143 MIR145 MIR146B MIR150 MIR16-1 MIR16-2 MIR17 MIR181A1 MIR181A2 MIR181B1 MIR181B2 MIR181C MIR181D MIR199A1 MIR199A2 MIR203A MIR206 MIR20A MIR214 MIR221 MIR222 MIR223 MIR26A1 MIR26A2 MIR302A MIR302C MIR302D MIR302E MIR3074 MIR3591 MIR486-1 MIR486-2 MIR9-1 MYOD1 PAX7 RUNX2 SOX2 SRF STAT3 TLX1 TLX2 TLX3 (see all 58) (see less)
2	Cell differentiation - index	WikiPathways	HDAC5 LEFTY1 LEFTY2 MIR133A1 MIR133A2 MIR145 MIR155 MIR17 MIR206 MIR20A MIR214 MIR221 MIR222 MIR223 MIR26A1 MIR26A2 SRF STAT3 TLX1 TLX2 TLX3 (see all 21) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	LEFTY2	Left-Right Determination Factor 2	Protein Coding	2
2	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	2
3	SRF	Serum Response Factor	Protein Coding	2
4	MIR26A1	MicroRNA 26a-1	RNA Gene	2
5	MIR223	MicroRNA 223	RNA Gene	2
6	MIR222	MicroRNA 222	RNA Gene	2
7	MIR221	MicroRNA 221	RNA Gene	2
8	MIR214	MicroRNA 214	RNA Gene	2
9	MIR206	MicroRNA 206	RNA Gene	2
10	MIR20A	MicroRNA 20a	RNA Gene	2
11	MIR17	MicroRNA 17	RNA Gene	2
12	MIR145	MicroRNA 145	RNA Gene	2
13	MIR133A2	MicroRNA 133a-2	RNA Gene	2
14	MIR133A1	MicroRNA 133a-1	RNA Gene	2
15	TLX1	T Cell Leukemia Homeobox 1	Protein Coding	2
16	HDAC5	Histone Deacetylase 5	Protein Coding	2
17	LEFTY1	Left-Right Determination Factor 1	Protein Coding	2
18	MIR26A2	MicroRNA 26a-2	RNA Gene	2
19	TLX2	T Cell Leukemia Homeobox 2	Protein Coding	2
20	TLX3	T Cell Leukemia Homeobox 3	Protein Coding	2
21	KLF4	KLF Transcription Factor 4	Protein Coding	1
22	RUNX2	RUNX Family Transcription Factor 2	Protein Coding	1
23	SOX2	SRY-Box Transcription Factor 2	Protein Coding	1
24	MIR486-1	MicroRNA 486-1	RNA Gene	1
25	MIR181D	MicroRNA 181d	RNA Gene	1
26	MIR146B	MicroRNA 146b	RNA Gene	1
27	PAX7	Paired Box 7	Protein Coding	1
28	MYOD1	Myogenic Differentiation 1	Protein Coding	1
29	MIR302D	MicroRNA 302d	RNA Gene	1
30	MIR302C	MicroRNA 302c	RNA Gene	1
31	MEF2D	Myocyte Enhancer Factor 2D	Protein Coding	1
32	MEF2C	Myocyte Enhancer Factor 2C	Protein Coding	1
33	MEF2A	Myocyte Enhancer Factor 2A	Protein Coding	1
34	MIR9-1	MicroRNA 9-1	RNA Gene	1
35	MIR181A1	MicroRNA 181a-1	RNA Gene	1
36	MIR203A	MicroRNA 203a	RNA Gene	1
37	MIR199A2	MicroRNA 199a-2	RNA Gene	1
38	MIR181C	MicroRNA 181c	RNA Gene	1
39	MIR16-1	MicroRNA 16-1	RNA Gene	1
40	MIR150	MicroRNA 150	RNA Gene	1
41	MIR143	MicroRNA 143	RNA Gene	1
42	MIR128-1	MicroRNA 128-1	RNA Gene	1
43	MIR1-1	MicroRNA 1-1	RNA Gene	1
44	MIR106A	MicroRNA 106a	RNA Gene	1
45	ID2	Inhibitor Of DNA Binding 2	Protein Coding	1
46	EZH2	Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit	Protein Coding	1
47	MIR3591	MicroRNA 3591	RNA Gene	1
48	MIR486-2	MicroRNA 486-2	RNA Gene	1
49	MIR133B	MicroRNA 133b	RNA Gene	1
50	MIR302A	MicroRNA 302a	RNA Gene	1
51	MIR199A1	MicroRNA 199a-1	RNA Gene	1
52	MIR181B2	MicroRNA 181b-2	RNA Gene	1
53	MIR181B1	MicroRNA 181b-1	RNA Gene	1
54	MIR181A2	MicroRNA 181a-2	RNA Gene	1
55	MIR16-2	MicroRNA 16-2	RNA Gene	1
56	MIR3074	MicroRNA 3074	RNA Gene	1
57	MIR302E	MicroRNA 302e	RNA Gene	1
58	MEF2B	Myocyte Enhancer Factor 2B	Protein Coding	1
59	MIR155	MicroRNA 155	RNA Gene	1

Disorders associated with Cell differentiation - expanded index SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Precursor t-cell acute lymphoblastic leukemia	Enrichment	TLX1, TLX3	3.25
2	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	2.81
3	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	2.81
4	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	2.81
5	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	2.81
6	Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Enrichment	MEF2C	2.37
7	Coronary artery disease, autosomal dominant, 1	Enrichment	MEF2A	2.37
8	Congenital myopathy 19	Enrichment	PAX7	2.37
9	Congenital myopathy 17	Enrichment	MYOD1	2.37
10	5q14.3 microdeletion syndrome	Enrichment	MEF2C	2.37
11	Complete atrioventricular septal defect without ventricular hypoplasia	Enrichment	MEF2C	2.37
12	Mef2c-related disorder	Enrichment	MEF2C	2.37
13	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	STAT3	2.33
14	Breast implant-associated anaplastic large cell lymphoma	Enrichment	STAT3	2.33
15	Hyper ige syndrome	Enrichment	STAT3	2.33
16	Metaphyseal dysplasia with maxillary hypoplasia with or without brachydactyly	Enrichment	RUNX2	2.07
17	Permanent neonatal diabetes mellitus	Enrichment	STAT3	1.91
18	Cleidocranial dysplasia 1	Enrichment	RUNX2	1.89
19	Weaver syndrome	Enrichment	EZH2	1.89
20	Cleidocranial dysplasia	Enrichment	RUNX2	1.89
21	Microphthalmia, syndromic 3	Enrichment	SOX2	1.77
22	Acute promyelocytic leukemia	Enrichment	STAT3	1.70
23	Rhabdomyosarcoma 2	Enrichment	PAX7	1.67
24	Myopathy, centronuclear, 1	Enrichment	MYOD1	1.60
25	Diffuse large b-cell lymphoma	Enrichment	STAT3	1.54
26	Visceral heterotaxy	Enrichment	LEFTY2	1.47
27	Nanophthalmos	Enrichment	SOX2	1.34
28	Septooptic dysplasia	Enrichment	SOX2	1.30
29	Macs syndrome	Enrichment	SOX2	1.09
30	Microphthalmia	Enrichment	SOX2	1.05
31	Fetal akinesia deformation sequence 1	Enrichment	MYOD1	0.83
32	Distal arthrogryposis	Enrichment	MYOD1	0.78
33	Nephrotic syndrome	Enrichment	RUNX2	0.77
34	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	MEF2C	0.66
35	Autism spectrum disorder	Enrichment	MEF2C	0.43
36	Inherited cancer-predisposing syndrome	Enrichment	EZH2	0.36

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Cell differentiation - expanded index

Pathway Network for Cell differentiation - expanded index

Member Pathways for Cell differentiation - expanded index

Pathways in the Cell differentiation - expanded index SuperPath

Associated Genes for Cell differentiation - expanded index

Associated Disorders for Cell differentiation - expanded index

Disorders associated with Cell differentiation - expanded index SuperPath

STRING Interaction Network for Cell differentiation - expanded index

Sources for Cell differentiation - expanded index