Cells and molecules involved in local acute inflammatory response

No Pathway Network information available for Cells and molecules involved in local acute inflammatory response

#	Name	Source	Genes
1	Cells and molecules involved in local acute inflammatory response	WikiPathways	CXCL8 IL6 KNG1 TNF
2	IL8-mediated signaling events	PubChem	CXCL8

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	2
2	TNF	Tumor Necrosis Factor	Protein Coding	1
3	KNG1	Kininogen 1	Protein Coding	1
4	IL6	Interleukin 6	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	High molecular weight kininogen deficiency	Enrichment	KNG1	3.53
2	Angioedema, hereditary, 6	Enrichment	KNG1	3.53
3	Immunodeficiency 127	Enrichment	TNF	3.23
4	Psoriatic arthritis	Enrichment	TNF	3.05
5	Migraine without aura	Enrichment	TNF	3.05
6	Kaposi sarcoma	Enrichment	IL6	2.93
7	Cerebral malaria	Enrichment	TNF	2.93
8	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	2.93
9	Hereditary angioedema with normal c1inh not related to f12 or plg variant	Enrichment	KNG1	2.93
10	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	2.83
11	Vascular dementia	Enrichment	TNF	2.83
12	Type 1 diabetes mellitus	Enrichment	IL6	2.75
13	Inflammatory bowel disease 1	Enrichment	IL6	2.58
14	Asthma	Enrichment	TNF	2.49
15	Alzheimer's disease	Enrichment	TNF	2.42
16	Arteriovenous malformations of the brain	Enrichment	IL6	2.25
17	Malaria	Enrichment	TNF	2.17
18	Systemic lupus erythematosus	Enrichment	TNF	1.94
19	Type 2 diabetes mellitus	Enrichment	IL6	1.91

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Cells and molecules involved in local acute inflammatory response