Cellular hexose transport

Pathway network for the Cellular hexose transport SuperPath

Sources:

Reactome

Pathways in the Cellular hexose transport SuperPath

#	Name	Source	Genes
1	Cellular hexose transport	Reactome	FGF21 SLC2A1 SLC2A10 SLC2A11 SLC2A12 SLC2A14 SLC2A2 SLC2A3 SLC2A4 SLC2A6 SLC2A7 SLC2A8 SLC2A9 SLC45A3 SLC50A1 SLC5A1 SLC5A10 SLC5A2 SLC5A4 SLC5A9 SLC60A2 (see all 21) (see less)
2	Defective SLC5A2 causes renal glucosuria (GLYS1)	Reactome	SLC5A2
3	Defective SLC2A10 causes arterial tortuosity syndrome (ATS)	Reactome	SLC2A10

Gene overlap in member pathways for Cellular hexose transport SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SLC5A2	Solute Carrier Family 5 Member 2	Protein Coding	2
2	SLC2A10	Solute Carrier Family 2 Member 10	Protein Coding	2
3	SLC2A6	Solute Carrier Family 2 Member 6	Protein Coding	1
4	SLC5A10	Solute Carrier Family 5 Member 10	Protein Coding	1
5	SLC2A14	Solute Carrier Family 2 Member 14	Protein Coding	1
6	SLC2A12	Solute Carrier Family 2 Member 12	Protein Coding	1
7	SLC2A7	Solute Carrier Family 2 Member 7	Protein Coding	1
8	SLC5A9	Solute Carrier Family 5 Member 9	Protein Coding	1
9	FGF21	Fibroblast Growth Factor 21	Protein Coding	1
10	SLC2A8	Solute Carrier Family 2 Member 8	Protein Coding	1
11	SLC50A1	Solute Carrier Family 50 Member 1	Protein Coding	1
12	SLC2A9	Solute Carrier Family 2 Member 9	Protein Coding	1
13	SLC2A1	Solute Carrier Family 2 Member 1	Protein Coding	1
14	SLC2A2	Solute Carrier Family 2 Member 2	Protein Coding	1
15	SLC2A3	Solute Carrier Family 2 Member 3	Protein Coding	1
16	SLC2A4	Solute Carrier Family 2 Member 4	Protein Coding	1
17	SLC5A1	Solute Carrier Family 5 Member 1	Protein Coding	1
18	SLC5A4	Solute Carrier Family 5 Member 4	Protein Coding	1
19	SLC2A11	Solute Carrier Family 2 Member 11	Protein Coding	1
20	SLC45A3	Solute Carrier Family 45 Member 3	Protein Coding	1
21	SLC60A2	Solute Carrier Family 60 Member 2	Protein Coding	1

Disorders associated with Cellular hexose transport SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Renal tubular transport disease	Direct
2	Arterial tortuosity syndrome	Direct
3	Renal glucosuria	Enrichment	SLC5A1, SLC5A2	4.86
4	Stomatin-deficient cryohydrocytosis with neurologic defects	Enrichment	SLC2A1	2.81
5	Glucose/galactose malabsorption	Enrichment	SLC5A1	2.81
6	Epilepsy, idiopathic generalized 12	Enrichment	SLC2A1	2.81
7	Epilepsy with myoclonic absences	Enrichment	SLC2A1	2.81
8	Hereditary cryohydrocytosis with reduced stomatin	Enrichment	SLC2A1	2.81
9	Type 2 diabetes mellitus	Enrichment	SLC2A2, SLC2A4	2.72
10	Fanconi-bickel syndrome	Enrichment	SLC2A2	2.51
11	Dystonia 9	Enrichment	SLC2A1	2.51
12	Glut1 deficiency syndrome 1	Enrichment	SLC2A1	2.51
13	Hypouricemia, renal, 2	Enrichment	SLC2A9	2.51
14	Glucose transporter type 1 deficiency syndrome	Enrichment	SLC2A1	2.51
15	Familial renal hypouricemia	Enrichment	SLC2A9	2.51
16	Glut1 deficiency syndrome 2	Enrichment	SLC2A1	2.33
17	Chromosome 17q23.1-q23.2 deletion syndrome	Enrichment	SLC2A1	2.33
18	Familial renal glucosuria	Enrichment	SLC5A2	2.33
19	Huntington disease	Enrichment	SLC2A3	2.21
20	Paroxysmal dystonia	Enrichment	SLC2A1	1.97
21	Alternating hemiplegia of childhood	Enrichment	SLC2A1	1.91
22	Myoclonic-atonic epilepsy	Enrichment	SLC2A1	1.86
23	Congenital long qt syndrome	Enrichment	SLC2A2	1.73
24	Developmental and epileptic encephalopathy 1	Enrichment	SLC2A1	1.42
25	Strabismus	Enrichment	SLC2A1	1.39
26	Long qt syndrome 1	Enrichment	SLC2A2	1.34
27	Epilepsy	Enrichment	SLC2A1	1.22
28	Benign epilepsy with centrotemporal spikes	Enrichment	SLC2A1	1.21
29	Centralopathic epilepsy	Enrichment	SLC2A1	1.19
30	West syndrome	Enrichment	SLC2A1	1.18
31	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SLC2A10	1.18
32	Microcephaly	Enrichment	SLC2A1	0.76

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Cellular hexose transport

Pathway Network for Cellular hexose transport

Pathway network for the Cellular hexose transport SuperPath

Member Pathways for Cellular hexose transport

Pathways in the Cellular hexose transport SuperPath

Gene overlap in member pathways for Cellular hexose transport SuperPath

Associated Genes for Cellular hexose transport

Associated Disorders for Cellular hexose transport

Disorders associated with Cellular hexose transport SuperPath

STRING Interaction Network for Cellular hexose transport

Sources for Cellular hexose transport