Cellular response to mitochondrial stress
Pathways in the Cellular response to mitochondrial stress SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Cellular response to mitochondrial stress | Reactome |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | YME1L1 | YME1 Like 1 ATPase | Protein Coding | 1 |
| 2 | PHB2 | Prohibitin 2 | Protein Coding | 1 |
| 3 | OMA1 | OMA1 Zinc Metallopeptidase | Protein Coding | 1 |
| 4 | EIF2S1 | Eukaryotic Translation Initiation Factor 2 Subunit Alpha | Protein Coding | 1 |
| 5 | EIF2S3 | Eukaryotic Translation Initiation Factor 2 Subunit Gamma | Protein Coding | 1 |
| 6 | EIF2AK1 | Eukaryotic Translation Initiation Factor 2 Alpha Kinase 1 | Protein Coding | 1 |
| 7 | STOML2 | Stomatin Like 2 | Protein Coding | 1 |
| 8 | EIF2S2 | Eukaryotic Translation Initiation Factor 2 Subunit Beta | Protein Coding | 1 |
| 9 | DELE1 | DAP3 Binding Cell Death Enhancer 1 | Protein Coding | 1 |
Disorders associated with Cellular response to mitochondrial stress SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Mehmo syndrome | Enrichment | EIF2S3 | 3.18 |
| 2 | Leukoencephalopathy, motor delay, spasticity, and dysarthria syndrome | Enrichment | EIF2AK1 | 3.18 |
| 3 | Optic atrophy 11 | Enrichment | YME1L1 | 3.18 |
| 4 | Leukodystrophy, hypomyelinating, 17 | Enrichment | EIF2AK1 | 2.88 |
| 5 | 3-methylglutaconic aciduria | Enrichment | YME1L1 | 2.70 |
| 6 | Autosomal recessive isolated optic atrophy | Enrichment | YME1L1 | 2.58 |
