Ceramide Pathway
Pathways in the Ceramide Pathway SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Ceramide Pathway | QIAGEN | |
| 2 | TNF-Induced Apoptosis Implicating Sphingolipids | QIAGEN |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | BAD | BCL2 Associated Agonist Of Cell Death | Protein Coding | 2 |
| 2 | CASP1 | Caspase 1 | Protein Coding | 2 |
| 3 | CASP10 | Caspase 10 | Protein Coding | 2 |
| 4 | CASP2 | Caspase 2 | Protein Coding | 2 |
| 5 | CASP3 | Caspase 3 | Protein Coding | 2 |
| 6 | CASP4 | Caspase 4 | Protein Coding | 2 |
| 7 | CASP5 | Caspase 5 | Protein Coding | 2 |
| 8 | CASP6 | Caspase 6 | Protein Coding | 2 |
| 9 | CASP7 | Caspase 7 | Protein Coding | 2 |
| 10 | CASP8 | Caspase 8 | Protein Coding | 2 |
| 11 | CASP9 | Caspase 9 | Protein Coding | 2 |
| 12 | CERK | Ceramide Kinase | Protein Coding | 2 |
| 13 | CTSD | Cathepsin D | Protein Coding | 2 |
| 14 | CYCS | Cytochrome C, Somatic | Protein Coding | 2 |
| 15 | FADD | Fas Associated Via Death Domain | Protein Coding | 2 |
| 16 | MAP2K1 | Mitogen-Activated Protein Kinase Kinase 1 | Protein Coding | 2 |
| 17 | MAP2K4 | Mitogen-Activated Protein Kinase Kinase 4 | Protein Coding | 2 |
| 18 | MAPK10 | Mitogen-Activated Protein Kinase 10 | Protein Coding | 2 |
| 19 | MAPK3 | Mitogen-Activated Protein Kinase 3 | Protein Coding | 2 |
| 20 | MAPK8 | Mitogen-Activated Protein Kinase 8 | Protein Coding | 2 |
| 21 | MAPK9 | Mitogen-Activated Protein Kinase 9 | Protein Coding | 2 |
| 22 | NSMAF | Neutral Sphingomyelinase Activation Associated Factor | Protein Coding | 2 |
| 23 | RAF1 | Raf-1 Proto-Oncogene, Serine/Threonine Kinase | Protein Coding | 2 |
| 24 | SMPD1 | Sphingomyelin Phosphodiesterase 1 | Protein Coding | 2 |
| 25 | SMPD3 | Sphingomyelin Phosphodiesterase 3 | Protein Coding | 2 |
| 26 | SPHK1 | Sphingosine Kinase 1 | Protein Coding | 2 |
| 27 | TNF | Tumor Necrosis Factor | Protein Coding | 2 |
| 28 | TNFRSF1A | TNF Receptor Superfamily Member 1A | Protein Coding | 2 |
| 29 | TRADD | TNFRSF1A Associated Via Death Domain | Protein Coding | 2 |
| 30 | TRAF2 | TNF Receptor Associated Factor 2 | Protein Coding | 2 |
| 31 | AKT1 | AKT Serine/Threonine Kinase 1 | Protein Coding | 1 |
| 32 | ATF1 | Activating Transcription Factor 1 | Protein Coding | 1 |
| 33 | ATF2 | Activating Transcription Factor 2 | Protein Coding | 1 |
| 34 | ATF3 | Activating Transcription Factor 3 | Protein Coding | 1 |
| 35 | ATF4 | Activating Transcription Factor 4 | Protein Coding | 1 |
| 36 | ATF5 | Activating Transcription Factor 5 | Protein Coding | 1 |
| 37 | ATF6 | Activating Transcription Factor 6 | Protein Coding | 1 |
| 38 | ATF7 | Activating Transcription Factor 7 | Protein Coding | 1 |
| 39 | BCL2 | BCL2 Apoptosis Regulator | Protein Coding | 1 |
| 40 | CNKSR1 | Connector Enhancer Of Kinase Suppressor Of Ras 1 | Protein Coding | 1 |
| 41 | S1PR1 | Sphingosine-1-Phosphate Receptor 1 | Protein Coding | 1 |
| 42 | S1PR3 | Sphingosine-1-Phosphate Receptor 3 | Protein Coding | 1 |
| 43 | S1PR2 | Sphingosine-1-Phosphate Receptor 2 | Protein Coding | 1 |
| 44 | S1PR4 | Sphingosine-1-Phosphate Receptor 4 | Protein Coding | 1 |
| 45 | S1PR5 | Sphingosine-1-Phosphate Receptor 5 | Protein Coding | 1 |
| 46 | FOS | Fos Proto-Oncogene, AP-1 Transcription Factor Subunit | Protein Coding | 1 |
| 47 | FOSB | FosB Proto-Oncogene, AP-1 Transcription Factor Subunit | Protein Coding | 1 |
| 48 | FOSL1 | FOS Like 1, AP-1 Transcription Factor Subunit | Protein Coding | 1 |
| 49 | FOSL2 | FOS Like 2, AP-1 Transcription Factor Subunit | Protein Coding | 1 |
| 50 | HRAS | HRas Proto-Oncogene, GTPase | Protein Coding | 1 |
| 51 | JUN | Jun Proto-Oncogene, AP-1 Transcription Factor Subunit | Protein Coding | 1 |
| 52 | JUNB | JunB Proto-Oncogene, AP-1 Transcription Factor Subunit | Protein Coding | 1 |
| 53 | JUND | JunD Proto-Oncogene, AP-1 Transcription Factor Subunit | Protein Coding | 1 |
| 54 | KRAS | KRAS Proto-Oncogene, GTPase | Protein Coding | 1 |
| 55 | MRAS | Muscle RAS Oncogene Homolog | Protein Coding | 1 |
| 56 | NFKB1 | Nuclear Factor Kappa B Subunit 1 | Protein Coding | 1 |
| 57 | NRAS | NRAS Proto-Oncogene, GTPase | Protein Coding | 1 |
| 58 | PIK3R5 | Phosphoinositide-3-Kinase Regulatory Subunit 5 | Protein Coding | 1 |
| 59 | PIK3R1 | Phosphoinositide-3-Kinase Regulatory Subunit 1 | Protein Coding | 1 |
| 60 | PIK3R2 | Phosphoinositide-3-Kinase Regulatory Subunit 2 | Protein Coding | 1 |
| 61 | PIK3R3 | Phosphoinositide-3-Kinase Regulatory Subunit 3 | Protein Coding | 1 |
| 62 | PIK3R4 | Phosphoinositide-3-Kinase Regulatory Subunit 4 | Protein Coding | 1 |
| 63 | PPP2CA | Protein Phosphatase 2 Catalytic Subunit Alpha | Protein Coding | 1 |
| 64 | PPP2CB | Protein Phosphatase 2 Catalytic Subunit Beta | Protein Coding | 1 |
| 65 | PPP2R1A | Protein Phosphatase 2 Scaffold Subunit Aalpha | Protein Coding | 1 |
| 66 | PPP2R1B | Protein Phosphatase 2 Scaffold Subunit Abeta | Protein Coding | 1 |
| 67 | PPP2R2A | Protein Phosphatase 2 Regulatory Subunit Balpha | Protein Coding | 1 |
| 68 | PPP2R2B | Protein Phosphatase 2 Regulatory Subunit Bbeta | Protein Coding | 1 |
| 69 | PPP2R2C | Protein Phosphatase 2 Regulatory Subunit Bgamma | Protein Coding | 1 |
| 70 | PPP2R3A | Protein Phosphatase 2 Regulatory Subunit B''''Alpha | Protein Coding | 1 |
| 71 | PTPA | Protein Phosphatase 2 Phosphatase Activator | Protein Coding | 1 |
| 72 | PPP2R5A | Protein Phosphatase 2 Regulatory Subunit B''Alpha | Protein Coding | 1 |
| 73 | PPP2R5B | Protein Phosphatase 2 Regulatory Subunit B''Beta | Protein Coding | 1 |
| 74 | PPP2R5C | Protein Phosphatase 2 Regulatory Subunit B''Gamma | Protein Coding | 1 |
| 75 | PPP2R5E | Protein Phosphatase 2 Regulatory Subunit B''Epsilon | Protein Coding | 1 |
| 76 | PPP2R3B | Protein Phosphatase 2 Regulatory Subunit B''''Beta~Name Same As:- HGNC:9310 | Protein Coding | 1 |
| 77 | PRKCD | Protein Kinase C Delta | Protein Coding | 1 |
| 78 | RIPK1 | Receptor Interacting Serine/Threonine Kinase 1 | Protein Coding | 1 |
| 79 | RRAS | RAS Related | Protein Coding | 1 |
| 80 | RRAS2 | RAS Related 2 | Protein Coding | 1 |
| 81 | BAX | BCL2 Associated X, Apoptosis Regulator | Protein Coding | 1 |
| 82 | MAP2K2 | Mitogen-Activated Protein Kinase Kinase 2 | Protein Coding | 1 |
| 83 | MAP2K3 | Mitogen-Activated Protein Kinase Kinase 3 | Protein Coding | 1 |
| 84 | MAP2K5 | Mitogen-Activated Protein Kinase Kinase 5 | Protein Coding | 1 |
| 85 | MAP2K6 | Mitogen-Activated Protein Kinase Kinase 6 | Protein Coding | 1 |
| 86 | MAPK1 | Mitogen-Activated Protein Kinase 1 | Protein Coding | 1 |
| 87 | MAPK11 | Mitogen-Activated Protein Kinase 11 | Protein Coding | 1 |
| 88 | MAPK12 | Mitogen-Activated Protein Kinase 12 | Protein Coding | 1 |
| 89 | MAPK13 | Mitogen-Activated Protein Kinase 13 | Protein Coding | 1 |
| 90 | MAPK14 | Mitogen-Activated Protein Kinase 14 | Protein Coding | 1 |
| 91 | MAPK6 | Mitogen-Activated Protein Kinase 6 | Protein Coding | 1 |
| 92 | MAPK7 | Mitogen-Activated Protein Kinase 7 | Protein Coding | 1 |
| 93 | SPHK2 | Sphingosine Kinase 2 | Protein Coding | 1 |
Disorders associated with Ceramide Pathway SuperPath
according to GeneCards Suite gene sharing