Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions

No Pathway Network information available for Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions

Pathways in the Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions SuperPath

#	Name	Source	Genes
1	Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions	R&D Systems	ACKR1 ACKR2 ACKR3 ACKR4 APOB CCL1 CCL11 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL4 CCL5 CCL7 CCL8 CCR1 CCR10 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCRL2 CX3CL1 CX3CR1 CXCL1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL16 CXCL17 CXCL2 CXCL3 CXCL5 CXCL6 CXCL8 CXCL9 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 PF4 PPBP XCL1 XCL2 XCR1 (see all 68) (see less)
2	Chemokine receptors bind chemokines	Reactome	ACKR2 ACKR3 ACKR4 CCL1 CCL11 CCL13 CCL16 CCL17 CCL19 CCL2 CCL20 CCL21 CCL22 CCL25 CCL27 CCL28 CCL3 CCL3L1 CCL3L3 CCL4 CCL4L1 CCL5 CCL7 CCR1 CCR10 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCRL2 CX3CL1 CX3CR1 CXCL1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL16 CXCL2 CXCL3 CXCL5 CXCL6 CXCL8 CXCL9 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 PF4 PPBP XCL1 XCL2 XCR1 (see all 59) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CCR1	C-C Motif Chemokine Receptor 1	Protein Coding	2
2	CCR2	C-C Motif Chemokine Receptor 2	Protein Coding	2
3	CCR3	C-C Motif Chemokine Receptor 3	Protein Coding	2
4	CCR4	C-C Motif Chemokine Receptor 4	Protein Coding	2
5	CCR5	C-C Motif Chemokine Receptor 5	Protein Coding	2
6	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	2
7	CCR7	C-C Motif Chemokine Receptor 7	Protein Coding	2
8	CCR8	C-C Motif Chemokine Receptor 8	Protein Coding	2
9	CCR9	C-C Motif Chemokine Receptor 9	Protein Coding	2
10	CCR10	C-C Motif Chemokine Receptor 10	Protein Coding	2
11	ACKR4	Atypical Chemokine Receptor 4	Protein Coding	2
12	CCRL2	C-C Motif Chemokine Receptor Like 2	Protein Coding	2
13	ACKR2	Atypical Chemokine Receptor 2	Protein Coding	2
14	XCR1	X-C Motif Chemokine Receptor 1	Protein Coding	2
15	CX3CR1	C-X3-C Motif Chemokine Receptor 1	Protein Coding	2
16	CXCR1	C-X-C Motif Chemokine Receptor 1	Protein Coding	2
17	CXCR2	C-X-C Motif Chemokine Receptor 2	Protein Coding	2
18	CXCR3	C-X-C Motif Chemokine Receptor 3	Protein Coding	2
19	CXCR4	C-X-C Motif Chemokine Receptor 4	Protein Coding	2
20	CXCR5	C-X-C Motif Chemokine Receptor 5	Protein Coding	2
21	CXCR6	C-X-C Motif Chemokine Receptor 6	Protein Coding	2
22	ACKR3	Atypical Chemokine Receptor 3	Protein Coding	2
23	CCL3	C-C Motif Chemokine Ligand 3	Protein Coding	2
24	CCL4	C-C Motif Chemokine Ligand 4	Protein Coding	2
25	CCL5	C-C Motif Chemokine Ligand 5	Protein Coding	2
26	CCL7	C-C Motif Chemokine Ligand 7	Protein Coding	2
27	CCL13	C-C Motif Chemokine Ligand 13	Protein Coding	2
28	CCL16	C-C Motif Chemokine Ligand 16	Protein Coding	2
29	CCL3L1	C-C Motif Chemokine Ligand 3 Like 1	Protein Coding	2
30	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	2
31	CCL11	C-C Motif Chemokine Ligand 11	Protein Coding	2
32	CCL28	C-C Motif Chemokine Ligand 28	Protein Coding	2
33	CCL17	C-C Motif Chemokine Ligand 17	Protein Coding	2
34	CCL22	C-C Motif Chemokine Ligand 22	Protein Coding	2
35	CCL20	C-C Motif Chemokine Ligand 20	Protein Coding	2
36	CCL19	C-C Motif Chemokine Ligand 19	Protein Coding	2
37	CCL21	C-C Motif Chemokine Ligand 21	Protein Coding	2
38	CCL1	C-C Motif Chemokine Ligand 1	Protein Coding	2
39	CCL25	C-C Motif Chemokine Ligand 25	Protein Coding	2
40	CCL27	C-C Motif Chemokine Ligand 27	Protein Coding	2
41	XCL1	X-C Motif Chemokine Ligand 1	Protein Coding	2
42	XCL2	X-C Motif Chemokine Ligand 2	Protein Coding	2
43	CX3CL1	C-X3-C Motif Chemokine Ligand 1	Protein Coding	2
44	CXCL6	C-X-C Motif Chemokine Ligand 6	Protein Coding	2
45	PPBP	Pro-Platelet Basic Protein	Protein Coding	2
46	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	2
47	CXCL1	C-X-C Motif Chemokine Ligand 1	Protein Coding	2
48	CXCL2	C-X-C Motif Chemokine Ligand 2	Protein Coding	2
49	CXCL3	C-X-C Motif Chemokine Ligand 3	Protein Coding	2
50	CXCL5	C-X-C Motif Chemokine Ligand 5	Protein Coding	2
51	PF4	Platelet Factor 4	Protein Coding	2
52	CXCL9	C-X-C Motif Chemokine Ligand 9	Protein Coding	2
53	CXCL10	C-X-C Motif Chemokine Ligand 10	Protein Coding	2
54	CXCL11	C-X-C Motif Chemokine Ligand 11	Protein Coding	2
55	CXCL13	C-X-C Motif Chemokine Ligand 13	Protein Coding	2
56	CXCL12	C-X-C Motif Chemokine Ligand 12	Protein Coding	2
57	CXCL16	C-X-C Motif Chemokine Ligand 16	Protein Coding	2
58	ACKR1	Atypical Chemokine Receptor 1 (Duffy Blood Group)	Protein Coding	1
59	CCL8	C-C Motif Chemokine Ligand 8	Protein Coding	1
60	CCL14	C-C Motif Chemokine Ligand 14	Protein Coding	1
61	CCL15	C-C Motif Chemokine Ligand 15	Protein Coding	1
62	CCL23	C-C Motif Chemokine Ligand 23	Protein Coding	1
63	APOB	Apolipoprotein B	Protein Coding	1
64	CCL24	C-C Motif Chemokine Ligand 24	Protein Coding	1
65	CCL26	C-C Motif Chemokine Ligand 26	Protein Coding	1
66	CCL18	C-C Motif Chemokine Ligand 18	Protein Coding	1
67	CXCL14	C-X-C Motif Chemokine Ligand 14	Protein Coding	1
68	CXCL17	C-X-C Motif Chemokine Ligand 17	Protein Coding	1
69	CCL4L1	C-C Motif Chemokine Ligand 4 Like 1	Protein Coding	1
70	CCL3L3	C-C Motif Chemokine Ligand 3 Like 3	Protein Coding	1

Disorders associated with Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Human immunodeficiency virus type 1	Enrichment	CCL11, CCL2, CCL3, CCL3L1, CCL5, CCR2, CCR5, CX3CR1, CXCL12, CXCR1	12.00
2	Polycystic lung disease	Enrichment	CCR2	2.36
3	Whim syndrome 1	Enrichment	CXCR4	2.36
4	Oculomotor-abducens synkinesis	Enrichment	ACKR3	2.36
5	Type 1 diabetes mellitus 22	Enrichment	CCR5	2.36
6	Macular degeneration, age-related, 12	Enrichment	CX3CR1	2.36
7	Whim syndrome 2	Enrichment	CXCR2	2.36
8	Autosomal recessive severe congenital neutropenia due to cxcr2 deficiency	Enrichment	CXCR2	2.36
9	White blood cell count quantitative trait locus 1	Enrichment	ACKR1	2.30
10	West nile virus	Enrichment	CCR5	2.06
11	Hypobetalipoproteinemia, familial, 1	Enrichment	APOB	2.00
12	Hypobetalipoproteinemia	Enrichment	APOB	2.00
13	Hepatitis c virus	Enrichment	CCR5	1.89
14	Hypercholesterolemia, familial, 2	Enrichment	APOB	1.82
15	Diffuse cutaneous systemic sclerosis	Enrichment	CCR6	1.67
16	Hyperlipidemia, familial combined, 3	Enrichment	APOB	1.61
17	Limited scleroderma	Enrichment	CCR6	1.59
18	Homozygous familial hypercholesterolemia	Enrichment	APOB	1.40
19	Coronary heart disease 5	Enrichment	APOB	1.35
20	Asthma	Enrichment	CCL11	1.33
21	Hypercholesterolemia, familial, 1	Enrichment	APOB	1.20
22	Familial hypercholesterolemia	Enrichment	APOB	1.14
23	Behcet syndrome	Enrichment	CCR1	1.10
24	Malaria	Enrichment	ACKR1	0.96

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions

Pathway Network for Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions

Member Pathways for Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions

Pathways in the Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions SuperPath

Associated Genes for Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions

Associated Disorders for Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions

Disorders associated with Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions SuperPath

STRING Interaction Network for Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions

Sources for Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions