Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)

No Pathway Network information available for Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)

Pathways in the Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF) SuperPath

#	Name	Source	Genes
1	Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)	GeneGo (Thomson Reuters)	ABCA1 ABCA7 ABCG1 APOA1 APOA2 APOA4 APOD APOL1 APOL2 APOL3 APOL4 APOL5 APOL6 CAV1 CFTR EHD3 RAB11A RAB11FIP2 SCP2 (see all 19) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ABCA1	ATP Binding Cassette Subfamily A Member 1	Protein Coding	1
2	APOA1	Apolipoprotein A1	Protein Coding	1
3	APOA2	Apolipoprotein A2	Protein Coding	1
4	APOA4	Apolipoprotein A4	Protein Coding	1
5	APOD	Apolipoprotein D	Protein Coding	1
6	CAV1	Caveolin 1	Protein Coding	1
7	CFTR	CF Transmembrane Conductance Regulator	Protein Coding	1
8	SCP2	Sterol Carrier Protein 2	Protein Coding	1
9	APOL1	Apolipoprotein L1	Protein Coding	1
10	RAB11A	RAB11A, Member RAS Oncogene Family	Protein Coding	1
11	ABCG1	ATP Binding Cassette Subfamily G Member 1	Protein Coding	1
12	ABCA7	ATP Binding Cassette Subfamily A Member 7	Protein Coding	1
13	RAB11FIP2	RAB11 Family Interacting Protein 2	Protein Coding	1
14	APOL2	Apolipoprotein L2	Protein Coding	1
15	EHD3	EH Domain Containing 3	Protein Coding	1
16	APOL6	Apolipoprotein L6	Protein Coding	1
17	APOL5	Apolipoprotein L5	Protein Coding	1
18	APOL4	Apolipoprotein L4	Protein Coding	1
19	APOL3	Apolipoprotein L3	Protein Coding	1

Disorders associated with Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF) SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hypoalphalipoproteinemia, primary, 2	Enrichment	ABCA1, APOA1	5.25
2	Hypoalphalipoproteinemia, primary, 1	Enrichment	ABCA1, APOA1	4.95
3	Lipodystrophy, congenital generalized, type 3	Enrichment	CAV1	2.85
4	Focal segmental glomerulosclerosis 4	Enrichment	APOL1	2.85
5	Pulmonary hypertension, primary, 3	Enrichment	CAV1	2.85
6	Tubulointerstitial kidney disease, autosomal dominant 6	Enrichment	APOA4	2.85
7	Lipodystrophy, familial partial, type 7	Enrichment	CAV1	2.85
8	Leukoencephalopathy with dystonia and motor neuropathy	Enrichment	SCP2	2.85
9	Aquagenic palmoplantar keratoderma	Enrichment	CFTR	2.85
10	Aapoaii amyloidosis	Enrichment	APOA2	2.85
11	Hypoalphalipoproteinemia	Enrichment	ABCA1	2.85
12	Tangier disease	Enrichment	ABCA1	2.55
13	Spermatogenic failure, y-linked, 2	Enrichment	CFTR	2.55
14	Alzheimer disease 9	Enrichment	ABCA7	2.55
15	Glomerulonephritis	Enrichment	APOL1	2.55
16	Hypoalphalipoproteinemia, primary, 2, intermediate	Enrichment	APOA1	2.55
17	Amyloidosis, hereditary systemic 3	Enrichment	APOA1	2.55
18	Schizophrenia	Enrichment	APOL2, APOL4	2.52
19	Nuchal bleb, familial	Enrichment	CFTR	2.38
20	Spastic paraplegia 50, autosomal recessive	Enrichment	APOA1	2.38
21	Idiopathic bronchiectasis	Enrichment	CFTR	2.25
22	Amyloidosis, hereditary systemic 2	Enrichment	APOA1	2.16
23	Diffuse cutaneous systemic sclerosis	Enrichment	CAV1	2.16
24	Limited scleroderma	Enrichment	CAV1	2.08
25	Early-onset autosomal dominant alzheimer disease	Enrichment	ABCA7	2.01
26	Bronchiectasis with or without elevated sweat chloride 1	Enrichment	CFTR	1.90
27	Vas deferens, congenital bilateral aplasia of	Enrichment	CFTR	1.90
28	Coronary heart disease 5	Enrichment	ABCA1	1.90
29	Heritable pulmonary arterial hypertension	Enrichment	CAV1	1.82
30	Hypercholesterolemia, familial, 1	Enrichment	APOA2	1.74
31	Hereditary chronic pancreatitis	Enrichment	CFTR	1.71
32	Familial hypercholesterolemia	Enrichment	APOA2	1.68
33	Lynch syndrome	Enrichment	CFTR	1.68
34	Isolated congenital microcephaly	Enrichment	RAB11A	1.65
35	Pancreatitis, hereditary	Enrichment	CFTR	1.63
36	Focal segmental glomerulosclerosis	Enrichment	APOL1	1.56
37	Cystic fibrosis	Enrichment	CFTR	1.36
38	Male infertility	Enrichment	CFTR	1.33
39	Genetic steroid-resistant nephrotic syndrome	Enrichment	APOL1	1.33
40	Autosomal dominant non-syndromic intellectual disability	Enrichment	RAB11A	1.17
41	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	CFTR	1.12
42	Breast cancer	Enrichment	ABCA1	1.00

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)

Pathway Network for Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)

Member Pathways for Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)

Pathways in the Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF) SuperPath

Associated Genes for Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)

Associated Disorders for Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)

Disorders associated with Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF) SuperPath

STRING Interaction Network for Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)

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