Chromosome Maintenance

No Pathway Network information available for Chromosome Maintenance

Pathways in the Chromosome Maintenance SuperPath

#	Name	Source	Genes
1	Chromosome Maintenance	Reactome	ACD ANKRD28 ATRX BLM CCNA1 CCNA2 CDK2 CENPA CENPC CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPS CENPS-CORT CENPT CENPU CENPW CENPX CHTF18 CHTF8 CTC1 DAXX DKC1 DNA2 DSCC1 FEN1 GAR1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AJ H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-3A H3-3B H3-4 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HJURP ITGB3BP KNL1 LIG1 MIS18A MIS18BP1 NHP2 NOP10 NPM1 OIP5 PCNA PIF1 POLA1 POLA2 POLD1 POLD2 POLD3 POLD4 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L POT1 PPP6C PPP6R3 PRIM1 PRIM2 RBBP4 RBBP7 RFC1 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 RSF1 RTEL1 RUVBL1 RUVBL2 SHQ1 SMARCA5 STN1 TEN1 TERF1 TERF2 TERF2IP TERT TINF2 WRAP53 WRN (see all 140) (see less)
2	Telomere Maintenance	Reactome	ACD ANKRD28 ATRX BLM CCNA1 CCNA2 CDK2 CHTF18 CHTF8 CTC1 DAXX DKC1 DNA2 DSCC1 FEN1 GAR1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AJ H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H3-3A H3-3B H3-4 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 LIG1 NHP2 NOP10 PCNA PIF1 POLA1 POLA2 POLD1 POLD2 POLD3 POLD4 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L POT1 PPP6C PPP6R3 PRIM1 PRIM2 RFC1 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 RTEL1 RUVBL1 RUVBL2 SHQ1 STN1 TEN1 TERF1 TERF2 TERF2IP TERT TINF2 WRAP53 WRN (see all 112) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TEN1	TEN1 Subunit Of CST Complex	Protein Coding	2
2	CDK2	Cyclin Dependent Kinase 2	Protein Coding	2
3	POLD3	DNA Polymerase Delta 3, Accessory Subunit	Protein Coding	2
4	RUVBL2	RuvB Like AAA ATPase 2	Protein Coding	2
5	H4C16	H4 Histone 16	Protein Coding	2
6	H2BC26	H2B Clustered Histone 26	Protein Coding	2
7	DAXX	Death Domain Associated Protein	Protein Coding	2
8	DKC1	Dyskerin Pseudouridine Synthase 1	Protein Coding	2
9	DNA2	DNA Replication Helicase/Nuclease 2	Protein Coding	2
10	FEN1	Flap Structure-Specific Endonuclease 1	Protein Coding	2
11	ANKRD28	Ankyrin Repeat Domain 28	Protein Coding	2
12	POLA2	DNA Polymerase Alpha 2, Accessory Subunit	Protein Coding	2
13	H2BC1	H2B Clustered Histone 1	Protein Coding	2
14	POT1	Protection Of Telomeres 1	Protein Coding	2
15	TINF2	TERF1 Interacting Nuclear Factor 2	Protein Coding	2
16	H2AC8	H2A Clustered Histone 8	Protein Coding	2
17	H2AC7	H2A Clustered Histone 7	Protein Coding	2
18	H2AX	H2A.X Variant Histone	Protein Coding	2
19	H2BC5	H2B Clustered Histone 5	Protein Coding	2
20	H2BC3	H2B Clustered Histone 3	Protein Coding	2
21	H3-3A	H3.3 Histone A	Protein Coding	2
22	H3-3B	H3.3 Histone B	Protein Coding	2
23	LIG1	DNA Ligase 1	Protein Coding	2
24	H2AB1	H2A.B Variant Histone 1	Protein Coding	2
25	PCNA	Proliferating Cell Nuclear Antigen	Protein Coding	2
26	RTEL1	Regulator Of Telomere Elongation Helicase 1	Protein Coding	2
27	H2BC12L	H2B Clustered Histone 12 Like	Protein Coding	2
28	POLA1	DNA Polymerase Alpha 1, Catalytic Subunit	Protein Coding	2
29	POLD1	DNA Polymerase Delta 1, Catalytic Subunit	Protein Coding	2
30	POLD2	DNA Polymerase Delta 2, Accessory Subunit	Protein Coding	2
31	POLR2A	RNA Polymerase II Subunit A	Protein Coding	2
32	POLR2B	RNA Polymerase II Subunit B	Protein Coding	2
33	POLR2C	RNA Polymerase II Subunit C	Protein Coding	2
34	POLR2D	RNA Polymerase II Subunit D	Protein Coding	2
35	POLR2E	RNA Polymerase II, I And III Subunit E	Protein Coding	2
36	POLR2F	RNA Polymerase II, I And III Subunit F	Protein Coding	2
37	POLR2G	RNA Polymerase II Subunit G	Protein Coding	2
38	POLR2H	RNA Polymerase II, I And III Subunit H	Protein Coding	2
39	POLR2I	RNA Polymerase II Subunit I	Protein Coding	2
40	TERF2IP	TERF2 Interacting Protein	Protein Coding	2
41	POLR2J	RNA Polymerase II Subunit J	Protein Coding	2
42	POLR2K	RNA Polymerase II, I And III Subunit K	Protein Coding	2
43	POLR2L	RNA Polymerase II, I And III Subunit L	Protein Coding	2
44	GAR1	GAR1 Ribonucleoprotein	Protein Coding	2
45	ATRX	ATRX Chromatin Remodeler	Protein Coding	2
46	CHTF8	Chromosome Transmission Fidelity Factor 8	Protein Coding	2
47	WRAP53	WD Repeat Containing Antisense To TP53	Protein Coding	2
48	SHQ1	SHQ1, H/ACA Ribonucleoprotein Assembly Factor	Protein Coding	2
49	PPP6R3	Protein Phosphatase 6 Regulatory Subunit 3	Protein Coding	2
50	PPP6C	Protein Phosphatase 6 Catalytic Subunit	Protein Coding	2
51	H4C15	H4 Clustered Histone 15	Protein Coding	2
52	NOP10	NOP10 Ribonucleoprotein	Protein Coding	2
53	PRIM1	DNA Primase Subunit 1	Protein Coding	2
54	PRIM2	DNA Primase Subunit 2	Protein Coding	2
55	NHP2	NHP2 Ribonucleoprotein	Protein Coding	2
56	H2AJ	H2A.J Histone	Protein Coding	2
57	POLD4	DNA Polymerase Delta 4, Accessory Subunit	Protein Coding	2
58	RFC1	Replication Factor C Subunit 1	Protein Coding	2
59	RFC2	Replication Factor C Subunit 2	Protein Coding	2
60	RFC3	Replication Factor C Subunit 3	Protein Coding	2
61	RFC4	Replication Factor C Subunit 4	Protein Coding	2
62	RFC5	Replication Factor C Subunit 5	Protein Coding	2
63	RPA1	Replication Protein A1	Protein Coding	2
64	RPA2	Replication Protein A2	Protein Coding	2
65	RPA3	Replication Protein A3	Protein Coding	2
66	CHTF18	Chromosome Transmission Fidelity Factor 18	Protein Coding	2
67	BLM	BLM RecQ Like Helicase	Protein Coding	2
68	ACD	ACD Shelterin Complex Subunit And Telomerase Recruitment Factor	Protein Coding	2
69	TERF1	Telomeric Repeat Binding Factor 1	Protein Coding	2
70	TERF2	Telomeric Repeat Binding Factor 2	Protein Coding	2
71	TERT	Telomerase Reverse Transcriptase	Protein Coding	2
72	H2AC19	H2A Clustered Histone 19	Protein Coding	2
73	WRN	WRN RecQ Like Helicase	Protein Coding	2
74	DSCC1	DNA Replication And Sister Chromatid Cohesion 1	Protein Coding	2
75	STN1	STN1 Subunit Of CST Complex	Protein Coding	2
76	PIF1	PIF1 5''-To-3'' DNA Helicase	Protein Coding	2
77	CTC1	CST Telomere Replication Complex Component 1	Protein Coding	2
78	H3-4	H3.4 Histone, Cluster Member	Protein Coding	2
79	H4C9	H4 Clustered Histone 9	Protein Coding	2
80	H2AC14	H2A Clustered Histone 14	Protein Coding	2
81	H2AC6	H2A Clustered Histone 6	Protein Coding	2
82	H2AC4	H2A Clustered Histone 4	Protein Coding	2
83	H2AC18	H2A Clustered Histone 18	Protein Coding	2
84	H2AC20	H2A Clustered Histone 20	Protein Coding	2
85	H2BC8	H2B Clustered Histone 8	Protein Coding	2
86	H2BC13	H2B Clustered Histone 13	Protein Coding	2
87	H2BC15	H2B Clustered Histone 15	Protein Coding	2
88	H2BC14	H2B Clustered Histone 14	Protein Coding	2
89	H2BC7	H2B Clustered Histone 7	Protein Coding	2
90	H2BC6	H2B Clustered Histone 6	Protein Coding	2
91	H2BC9	H2B Clustered Histone 9	Protein Coding	2
92	H2BC10	H2B Clustered Histone 10	Protein Coding	2
93	H2BC4	H2B Clustered Histone 4	Protein Coding	2
94	H2BC17	H2B Clustered Histone 17	Protein Coding	2
95	H2BC21	H2B Clustered Histone 21	Protein Coding	2
96	H4C1	H4 Clustered Histone 1	Protein Coding	2
97	H4C4	H4 Clustered Histone 4	Protein Coding	2
98	H4C6	H4 Clustered Histone 6	Protein Coding	2
99	H4C12	H4 Clustered Histone 12	Protein Coding	2
100	H4C11	H4 Clustered Histone 11	Protein Coding	2
101	H4C3	H4 Clustered Histone 3	Protein Coding	2
102	H4C8	H4 Clustered Histone 8	Protein Coding	2
103	H4C2	H4 Clustered Histone 2	Protein Coding	2
104	H4C5	H4 Clustered Histone 5	Protein Coding	2
105	H4C13	H4 Clustered Histone 13	Protein Coding	2
106	H4C14	H4 Clustered Histone 14	Protein Coding	2
107	H2BC12	H2B Clustered Histone 12	Protein Coding	2
108	RUVBL1	RuvB Like AAA ATPase 1	Protein Coding	2
109	CCNA2	Cyclin A2	Protein Coding	2
110	CCNA1	Cyclin A1	Protein Coding	2
111	H2BC11	H2B Clustered Histone 11	Protein Coding	2
112	H2AZ2	H2A.Z Variant Histone 2	Protein Coding	2
113	CENPS-CORT	CENPS-CORT Readthrough	Protein Coding	1
114	CENPA	Centromere Protein A	Protein Coding	1
115	CENPC	Centromere Protein C	Protein Coding	1
116	OIP5	Opa Interacting Protein 5	Protein Coding	1
117	CENPX	Centromere Protein X	Protein Coding	1
118	ITGB3BP	Integrin Subunit Beta 3 Binding Protein	Protein Coding	1
119	CENPI	Centromere Protein I	Protein Coding	1
120	CENPS	Centromere Protein S	Protein Coding	1
121	CENPW	Centromere Protein W	Protein Coding	1
122	CENPP	Centromere Protein P	Protein Coding	1
123	NPM1	Nucleophosmin 1	Protein Coding	1
124	RSF1	Remodeling And Spacing Factor 1	Protein Coding	1
125	MIS18A	MIS18 Kinetochore Protein A	Protein Coding	1
126	CENPQ	Centromere Protein Q	Protein Coding	1
127	MIS18BP1	MIS18 Binding Protein 1	Protein Coding	1
128	HJURP	Holliday Junction Recognition Protein	Protein Coding	1
129	CENPN	Centromere Protein N	Protein Coding	1
130	KNL1	Kinetochore Scaffold 1	Protein Coding	1
131	RBBP4	RB Binding Protein 4, Chromatin Remodeling Factor	Protein Coding	1
132	RBBP7	RB Binding Protein 7, Chromatin Remodeling Factor	Protein Coding	1
133	CENPK	Centromere Protein K	Protein Coding	1
134	CENPH	Centromere Protein H	Protein Coding	1
135	CENPM	Centromere Protein M	Protein Coding	1
136	CENPO	Centromere Protein O	Protein Coding	1
137	CENPU	Centromere Protein U	Protein Coding	1
138	CENPT	Centromere Protein T	Protein Coding	1
139	SMARCA5	SNF2 Related Chromatin Remodeling ATPase 5	Protein Coding	1
140	CENPL	Centromere Protein L	Protein Coding	1

Disorders associated with Chromosome Maintenance SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Dyskeratosis congenita	Enrichment	CTC1, DKC1, NHP2, NOP10, NPM1, POT1, RTEL1, TERT, TINF2, WRAP53	11.14
2	Hoyeraal-hreidarsson syndrome	Enrichment	ACD, DKC1, RTEL1, TERT, TINF2	9.63
3	Tessadori-bicknell-van haaften neurodevelopmental syndrome 4	Enrichment	H2BC12, H4C1, H4C9	6.26
4	Melanoma, cutaneous malignant 1	Enrichment	ACD, POT1, TERF2IP, TERT	5.02
5	Tessadori-bicknell-van haaften neurodevelopmental syndrome 1	Enrichment	H4C1, H4C3	4.17
6	Tessadori-bicknell-van haaften neurodevelopmental syndrome 2	Enrichment	H4C1, H4C11	4.17
7	Bryant-li-bhoj neurodevelopmental syndrome 2	Enrichment	H3-3A, H3-3B	4.17
8	Dyskeratosis congenita, x-linked	Enrichment	DKC1, RTEL1	3.70
9	Tessadori-bicknell-van haaften neurodevelopmental syndrome 3	Enrichment	H4C1, H4C5	3.70
10	Cerebroretinal microangiopathy with calcifications and cysts 1	Enrichment	CTC1, STN1	3.70
11	Interstitial lung disease 2	Enrichment	RTEL1, STN1, TERT	3.47
12	Dyskeratosis congenita, autosomal dominant 1	Enrichment	TERT, TINF2	3.00
13	Pulmonary fibrosis	Enrichment	RTEL1, TERT	3.00
14	Dyskeratosis congenita, autosomal dominant 2	Enrichment	TERT, TINF2	2.86
15	Seckel syndrome	Enrichment	DNA2, PRIM1	2.24
16	Leukemia, acute myeloid	Enrichment	NPM1, RTEL1, TERT	2.09
17	Bloom syndrome	Enrichment	BLM	2.08
18	Van esch-o'driscoll syndrome	Enrichment	POLA1	2.08
19	Colorectal cancer 10	Enrichment	POLD1	2.08
20	Dyskeratosis congenita, autosomal recessive 1	Enrichment	NOP10	2.08
21	Seckel syndrome 8	Enrichment	DNA2	2.08
22	Dyskeratosis congenita, autosomal recessive 3	Enrichment	WRAP53	2.08
23	Tumor predisposition syndrome 3	Enrichment	POT1	2.08
24	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 6	Enrichment	RPA1	2.08
25	Neurodevelopmental disorder with dystonia and seizures	Enrichment	SHQ1	2.08
26	Pigmentary disorder, reticulate, with systemic manifestations, x-linked	Enrichment	POLA1	2.08
27	Intellectual disability-hypotonic facies syndrome, x-linked, 1	Enrichment	ATRX	2.08
28	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 8	Enrichment	POT1	2.08
29	Immunodeficiency 120	Enrichment	POLD1	2.08
30	Cataracts, hearing impairment, nephrotic syndrome, and enterocolitis 2	Enrichment	NOP10	2.08
31	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 6	Enrichment	DNA2	2.08
32	Cataracts, hearing impairment, nephrotic syndrome, and enterocolitis 1	Enrichment	DKC1	2.08
33	High-grade astrocytoma with piloid features	Enrichment	POT1	2.08
34	Cerebroretinal microangiopathy with calcifications and cysts 3	Enrichment	POT1	2.08
35	Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome	Enrichment	POLD1	2.08
36	Ataxia-telangiectasia-like disorder 2	Enrichment	PCNA	2.08
37	Immunodeficiency 96	Enrichment	LIG1	2.08
38	Bryant-li-bhoj neurodevelopmental syndrome 1	Enrichment	H3-3A	2.08
39	Cerebroretinal microangiopathy with calcifications and cysts 2	Enrichment	STN1	2.08
40	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 9	Enrichment	NOP10	2.08
41	Autosomal recessive dyskeratosis congenita 4	Enrichment	TERT	2.08
42	Dystonia 35, childhood-onset	Enrichment	SHQ1	2.08
43	Rothmund-thomson syndrome, type 4	Enrichment	DNA2	2.08
44	Morimoto-ryu-malicdan neuromuscular syndrome	Enrichment	RFC4	2.08
45	Immunodeficiency 122	Enrichment	POLD3	2.08
46	Gastric neuroendocrine neoplasm	Enrichment	ATRX	2.08
47	Spermatogenic failure, x-linked, 9	Enrichment	RBBP7	1.99
48	Microcephaly 4, primary, autosomal recessive	Enrichment	KNL1	1.99
49	Short stature and microcephaly with genital anomalies	Enrichment	CENPT	1.99
50	Acute myeloid leukemia with multilineage dysplasia	Enrichment	NPM1	1.99
51	Acute myeloid leukemia with npm1 somatic mutations	Enrichment	NPM1	1.99
52	Revesz syndrome	Enrichment	TINF2	1.78
53	Rothmund-thomson syndrome, type 2	Enrichment	DNA2	1.78
54	Alpha-thalassemia myelodysplasia syndrome	Enrichment	ATRX	1.78
55	Waardenburg syndrome, type 4c	Enrichment	POLR2F	1.78
56	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 1	Enrichment	TERT	1.78
57	Dyskeratosis congenita, autosomal recessive 5	Enrichment	RTEL1	1.78
58	Dyskeratosis congenita, autosomal recessive 2	Enrichment	NHP2	1.78
59	Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome	Enrichment	RFC1	1.78
60	Alpha-thalassemia/impaired intellectual development syndrome, x-linked	Enrichment	ATRX	1.78
61	Immunodeficiency, common variable, 15	Enrichment	RUVBL1	1.78
62	Werner syndrome	Enrichment	WRN	1.78
63	Dyskeratosis congenita, autosomal dominant 3	Enrichment	TINF2	1.78
64	Autosomal dominant dyskeratosis congenita 4	Enrichment	RTEL1	1.78
65	Oligodendroglioma	Enrichment	POT1	1.78
66	Primordial dwarfism-immunodeficiency-lipodystrophy syndrome	Enrichment	PRIM1	1.78
67	Peripheral demyelinating neuropathy, central dysmyelination, waardenburg syndrome, and hirschsprung disease	Enrichment	POLR2F	1.78
68	Melanoma, cutaneous malignant 9	Enrichment	TERT	1.78
69	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 3	Enrichment	RTEL1	1.78
70	Idiopathic interstitial pneumonia	Enrichment	TERT	1.78
71	Anaplastic oligodendroglioma	Enrichment	POT1	1.78
72	Alpha thalassemia-x-linked intellectual disability syndrome	Enrichment	ATRX	1.78
73	Body mass index quantitative trait locus 19	Enrichment	CENPO	1.69
74	Degenerative disc disease	Enrichment	CENPP	1.69
75	Methylmalonic aciduria and homocystinuria, cbll type	Enrichment	CENPT	1.69
76	Acute myeloid leukemia without maturation	Enrichment	NPM1	1.69
77	Lymphomatoid papulosis	Enrichment	NPM1	1.69
78	Primary cutaneous anaplastic large cell lymphoma	Enrichment	NPM1	1.69
79	Inherited cancer-predisposing syndrome	Enrichment	BLM, POLD1, POT1, WRAP53	1.62
80	Waardenburg syndrome, type 2a	Enrichment	POLR2F	1.61
81	Partington syndrome	Enrichment	POLA1	1.61
82	Dyskeratosis congenita, autosomal dominant 6	Enrichment	ACD	1.61
83	Neurodevelopmental disorder with progressive spasticity and brain abnormalities	Enrichment	RUVBL1	1.61
84	Alpha thalassemia-intellectual disability syndrome type 1	Enrichment	ATRX	1.61
85	Torsion dystonia 1	Enrichment	SHQ1	1.61
86	Interstitial lung disease	Enrichment	TERT	1.61
87	Atypical teratoid rhabdoid tumor	Enrichment	ATRX	1.61
88	Anaplastic astrocytoma	Enrichment	ATRX	1.61
89	Macrocytic anemia	Enrichment	TERT	1.61
90	Childhood apraxia of speech	Enrichment	RFC3	1.61
91	Polymerase proofreading-related polyposis	Enrichment	POLD1	1.61
92	Methylmalonic aciduria and homocystinuria, cblx type	Enrichment	CENPT	1.51
93	Epilepsy, progressive myoclonic, 4, with or without renal failure	Enrichment	RTEL1	1.49
94	Neurodevelopmental disorder with hypotonia and variable intellectual and behavioral abnormalities	Enrichment	POLR2A	1.49
95	Lung sarcomatoid carcinoma	Enrichment	TERT	1.49
96	Combined oxidative phosphorylation deficiency 24	Enrichment	RTEL1	1.49
97	Hypogonadotropic hypogonadism 1 with or without anosmia	Enrichment	POLR2F	1.39
98	Idiopathic aplastic anemia	Enrichment	TERT	1.39
99	Li-fraumeni syndrome	Enrichment	WRAP53	1.31
100	Waardenburg syndrome, type 4a	Enrichment	POLR2F	1.31
101	Adrenocortical carcinoma	Enrichment	TERT	1.31
102	Waardenburg syndrome	Enrichment	POLR2F	1.31
103	Kidney clear cell sarcoma	Enrichment	TERT	1.31
104	Acute myeloid leukemia with maturation	Enrichment	NPM1	1.30
105	Waardenburg syndrome, type 1	Enrichment	POLR2F	1.25
106	Waardenburg syndrome, type 2e	Enrichment	POLR2F	1.25
107	Glioma susceptibility 1	Enrichment	H3-3A	1.19
108	Isolated growth hormone deficiency, type ia	Enrichment	DNA2	1.19
109	Primary hyperaldosteronism	Enrichment	ATRX	1.14
110	Leukemia, chronic lymphocytic	Enrichment	POT1	1.10
111	Aplastic anemia	Enrichment	TERT	1.10
112	Ewing sarcoma	Enrichment	SMARCA5	1.10
113	Complex neurodevelopmental disorder	Enrichment	H4C3, H4C5, H4C9	1.08
114	Combined immunodeficiency	Enrichment	POLD1	1.06
115	Combined t cell and b cell immunodeficiency	Enrichment	POLD1	1.06
116	Familial colorectal cancer type x	Enrichment	POLD1	1.06
117	Combined t and b cell immunodeficiency	Enrichment	POLD1	1.06
118	Meningioma	Enrichment	TERT	1.02
119	Medulloblastoma	Enrichment	WRN	0.96
120	Cataract	Enrichment	WRN	0.96
121	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	DKC1	0.91
122	Acute promyelocytic leukemia	Enrichment	NPM1	0.90
123	Polycystic liver disease	Enrichment	RUVBL1	0.88
124	Autosomal dominant polycystic liver disease	Enrichment	RUVBL1	0.88
125	Esophageal atresia/tracheoesophageal fistula	Enrichment	POLR2B	0.84
126	Parkinson's disease	Enrichment	RFC1	0.84
127	Williams-beuren syndrome	Enrichment	RFC2	0.82
128	Endometrial cancer	Enrichment	BLM	0.80
129	Hepatoblastoma	Enrichment	TERT	0.80
130	Colorectal cancer	Enrichment	BLM, POLD1	0.79
131	Hepatocellular carcinoma	Enrichment	TERT	0.78
132	Kallmann syndrome	Enrichment	POLR2F	0.76
133	Parkinson disease, late-onset	Enrichment	RFC1	0.74
134	Pancreatic cancer	Enrichment	POLD1	0.73
135	Ovarian cancer	Enrichment	BLM, WRN	0.69
136	Bladder cancer	Enrichment	TERT	0.67
137	Hirschsprung disease 1	Enrichment	POLR2F	0.67
138	Differentiated thyroid carcinoma	Enrichment	TERT	0.67
139	Primary autosomal recessive microcephaly	Enrichment	KNL1	0.55
140	Type 2 diabetes mellitus	Enrichment	WRN	0.53
141	Hereditary breast carcinoma	Enrichment	BLM	0.51
142	Microcephaly	Enrichment	ATRX, SMARCA5	0.44
143	Hereditary breast ovarian cancer syndrome	Enrichment	BLM	0.44
144	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	ATRX	0.43
145	Body mass index quantitative trait locus 11	Enrichment	CENPO	0.39
146	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	CENPP	0.38
147	Breast cancer	Enrichment	BLM	0.33
148	Rare genetic deafness	Enrichment	POLR2F	0.32
149	Congenital nervous system abnormality	Enrichment	ATRX	0.23
150	Nervous system disease	Enrichment	ATRX	0.23

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Chromosome Maintenance

Pathway Network for Chromosome Maintenance

Member Pathways for Chromosome Maintenance

Pathways in the Chromosome Maintenance SuperPath

Associated Genes for Chromosome Maintenance

Associated Disorders for Chromosome Maintenance

Disorders associated with Chromosome Maintenance SuperPath

STRING Interaction Network for Chromosome Maintenance

Sources for Chromosome Maintenance