Clear cell renal cell carcinoma pathways

No Pathway Network information available for Clear cell renal cell carcinoma pathways

Pathways in the Clear cell renal cell carcinoma pathways SuperPath

#	Name	Source	Genes
1	Clear cell renal cell carcinoma pathways	WikiPathways	ACACA ACACB ACLY AKT1 AKT1S1 ALDOA ALDOB ALDOC ARNT BAP1 BHLHE41 CAMK1 CDH13 CEP290 CREBBP DEPTOR EFCAB3 EGFR ENO1 ENO2 ENO3 ENPP3 EP300 FASN FLT1 GAPDH GPI GRB10 HIF1A HK1 HK2 HK3 KCNJ2 KDM5C KDR KSR1 LDHA LDHB LDHC LDHD MDH1 ME1 MLST8 MTOR PBRM1 PDGFB PDGFRA PDGFRB PFKL PFKM PFKP PGBD5 PGK1 PGK2 PGM1 PGM2 PHGDH PKLR PKM PLOD2 PSAT1 PSPH PTEN RAPGEF5 RHEB RPTOR SDS SDSL SETD2 SHMT1 SHMT2 SLC2A1 SQSTM1 SSPN STAT3 TGFB1 TGFB2 TGFB3 TOX2 TPI1 TSC1 TSC2 VEGFA VHL ZEB1 (see all 85) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PGM2	Phosphoglucomutase 2	Protein Coding	1
2	PGK2	Phosphoglycerate Kinase 2	Protein Coding	1
3	PFKL	Phosphofructokinase, Liver Type	Protein Coding	1
4	ENPP3	Ectonucleotide Pyrophosphatase/Phosphodiesterase 3	Protein Coding	1
5	ALDOC	Aldolase, Fructose-Bisphosphate C	Protein Coding	1
6	LDHD	Lactate Dehydrogenase D	Protein Coding	1
7	RAPGEF5	Rap Guanine Nucleotide Exchange Factor 5	Protein Coding	1
8	SQSTM1	Sequestosome 1	Protein Coding	1
9	AKT1S1	AKT1 Substrate 1	Protein Coding	1
10	BAP1	BRCA1 Associated Deubiquitinase 1	Protein Coding	1
11	KDM5C	Lysine Demethylase 5C	Protein Coding	1
12	SSPN	Sarcospan	Protein Coding	1
13	CEP290	Centrosomal Protein 290	Protein Coding	1
14	PGBD5	PiggyBac Transposable Element Derived 5	Protein Coding	1
15	BHLHE41	Basic Helix-Loop-Helix Family Member E41	Protein Coding	1
16	VHL	Von Hippel-Lindau Tumor Suppressor	Protein Coding	1
17	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1
18	TSC2	TSC Complex Subunit 2	Protein Coding	1
19	TSC1	TSC Complex Subunit 1	Protein Coding	1
20	TPI1	Triosephosphate Isomerase 1	Protein Coding	1
21	TGFB3	Transforming Growth Factor Beta 3	Protein Coding	1
22	TGFB2	Transforming Growth Factor Beta 2	Protein Coding	1
23	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
24	ZEB1	Zinc Finger E-Box Binding Homeobox 1	Protein Coding	1
25	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	1
26	SLC2A1	Solute Carrier Family 2 Member 1	Protein Coding	1
27	SHMT2	Serine Hydroxymethyltransferase 2	Protein Coding	1
28	SHMT1	Serine Hydroxymethyltransferase 1	Protein Coding	1
29	RHEB	Ras Homolog, MTORC1 Binding	Protein Coding	1
30	RPTOR	Regulatory Associated Protein Of MTOR Complex 1	Protein Coding	1
31	PTEN	Phosphatase And Tensin Homolog	Protein Coding	1
32	PSPH	Phosphoserine Phosphatase	Protein Coding	1
33	PBRM1	Polybromo 1	Protein Coding	1
34	PLOD2	Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 2	Protein Coding	1
35	PKM	Pyruvate Kinase M1/2	Protein Coding	1
36	PKLR	Pyruvate Kinase L/R	Protein Coding	1
37	PGM1	Phosphoglucomutase 1	Protein Coding	1
38	PGK1	Phosphoglycerate Kinase 1	Protein Coding	1
39	PFKP	Phosphofructokinase, Platelet	Protein Coding	1
40	PFKM	Phosphofructokinase, Muscle	Protein Coding	1
41	PDGFRB	Platelet Derived Growth Factor Receptor Beta	Protein Coding	1
42	PDGFRA	Platelet Derived Growth Factor Receptor Alpha	Protein Coding	1
43	PDGFB	Platelet Derived Growth Factor Subunit B	Protein Coding	1
44	ACLY	ATP Citrate Lyase	Protein Coding	1
45	ME1	Malic Enzyme 1	Protein Coding	1
46	MDH1	Malate Dehydrogenase 1	Protein Coding	1
47	ARNT	Aryl Hydrocarbon Receptor Nuclear Translocator	Protein Coding	1
48	LDHC	Lactate Dehydrogenase C	Protein Coding	1
49	LDHB	Lactate Dehydrogenase B	Protein Coding	1
50	LDHA	Lactate Dehydrogenase A	Protein Coding	1
51	KDR	Kinase Insert Domain Receptor	Protein Coding	1
52	KCNJ2	Potassium Inwardly Rectifying Channel Subfamily J Member 2	Protein Coding	1
53	ACACB	Acetyl-CoA Carboxylase Beta	Protein Coding	1
54	HK3	Hexokinase 3	Protein Coding	1
55	ACACA	Acetyl-CoA Carboxylase Alpha	Protein Coding	1
56	HK2	Hexokinase 2	Protein Coding	1
57	HK1	Hexokinase 1	Protein Coding	1
58	HIF1A	Hypoxia Inducible Factor 1 Subunit Alpha	Protein Coding	1
59	PSAT1	Phosphoserine Aminotransferase 1	Protein Coding	1
60	SETD2	SET Domain Containing 2, Histone Lysine Methyltransferase	Protein Coding	1
61	GPI	Glucose-6-Phosphate Isomerase	Protein Coding	1
62	PHGDH	Phosphoglycerate Dehydrogenase	Protein Coding	1
63	GAPDH	Glyceraldehyde-3-Phosphate Dehydrogenase	Protein Coding	1
64	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	1
65	FLT1	Fms Related Receptor Tyrosine Kinase 1	Protein Coding	1
66	ALDOB	Aldolase, Fructose-Bisphosphate B	Protein Coding	1
67	ALDOA	Aldolase, Fructose-Bisphosphate A	Protein Coding	1
68	FASN	Fatty Acid Synthase	Protein Coding	1
69	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
70	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
71	ENO3	Enolase 3	Protein Coding	1
72	ENO2	Enolase 2	Protein Coding	1
73	ENO1	Enolase 1	Protein Coding	1
74	EGFR	Epidermal Growth Factor Receptor	Protein Coding	1
75	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
76	SDS	Serine Dehydratase	Protein Coding	1
77	CDH13	Cadherin 13	Protein Coding	1
78	EFCAB3	EF-Hand Calcium Binding Domain 3	Protein Coding	1
79	KSR1	Kinase Suppressor Of Ras 1	Protein Coding	1
80	CAMK1	Calcium/Calmodulin Dependent Protein Kinase I	Protein Coding	1
81	TOX2	TOX High Mobility Group Box Family Member 2	Protein Coding	1
82	SDSL	Serine Dehydratase Like	Protein Coding	1
83	DEPTOR	DEP Domain Containing MTOR Interacting Protein	Protein Coding	1
84	MLST8	MTOR Associated Protein MLST8	Protein Coding	1
85	GRB10	Growth Factor Receptor Bound Protein 10	Protein Coding	1

Disorders associated with Clear cell renal cell carcinoma pathways SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Focal cortical dysplasia, type ii	Enrichment	MTOR, RHEB, TSC1, TSC2	8.84
2	Isolated focal cortical dysplasia type ii	Enrichment	MTOR, RHEB, TSC1, TSC2	8.84
3	Renal cell carcinoma, nonpapillary	Enrichment	BAP1, MTOR, PBRM1, SETD2, VHL	7.61
4	Meningioma	Enrichment	AKT1, BAP1, PDGFB, PTEN	6.16
5	Hemimegalencephaly	Enrichment	MTOR, PTEN, RHEB	5.63
6	Inherited cancer-predisposing syndrome	Enrichment	BAP1, EGFR, PDGFRA, PTEN, TSC1, TSC2, VHL	4.73
7	Lymphangioleiomyomatosis	Enrichment	TSC1, TSC2	4.41
8	Loeys-dietz syndrome 4	Enrichment	TGFB2, TGFB3	4.41
9	Rare genetic intellectual disability	Enrichment	CREBBP, EP300, MTOR	3.99
10	Tuberous sclerosis 1	Enrichment	TSC1, TSC2	3.94
11	Hamartoma	Enrichment	TSC1, TSC2	3.94
12	Intraocular pressure quantitative trait locus	Enrichment	CREBBP, ZEB1	3.94
13	Diffuse large b-cell lymphoma	Enrichment	CREBBP, PTEN, STAT3	3.67
14	Tuberous sclerosis	Enrichment	TSC1, TSC2	3.64
15	Primary hypereosinophilic syndrome	Enrichment	PDGFRA, PDGFRB	3.42
16	Ovarian cancer	Enrichment	AKT1, EGFR, PDGFRA, PTEN, TSC2	3.37
17	Cowden syndrome 1	Enrichment	EGFR, PTEN	3.24
18	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	3.24
19	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	3.24
20	Clear cell renal cell carcinoma	Enrichment	BAP1, PBRM1	3.24
21	Bladder cancer	Enrichment	EGFR, PTEN, TSC1	3.11
22	Squamous cell carcinoma, head and neck	Enrichment	EGFR, PTEN	3.10
23	Renal cell carcinoma, papillary, 1	Enrichment	MTOR, VHL	3.10
24	Multiple enchondromatosis, maffucci type	Enrichment	HIF1A, VHL	3.10
25	Hemolytic anemia	Enrichment	GPI, PKLR	3.10
26	Basal ganglia calcification, idiopathic, 1	Enrichment	PDGFB, PDGFRB	2.97
27	Loeys-dietz syndrome	Enrichment	TGFB2, TGFB3	2.87
28	Adult hepatocellular carcinoma	Enrichment	TSC1, TSC2	2.87
29	Cowden syndrome	Enrichment	AKT1, PTEN	2.87
30	Meningioma, familial	Enrichment	PDGFB, PTEN	2.69
31	Corpus callosum, agenesis of	Enrichment	CREBBP, SETD2	2.41
32	Kidney disease	Enrichment	CEP290, TSC1	2.41
33	Isolated corpus callosum agenesis	Enrichment	CREBBP, SETD2	2.41
34	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP, SETD2	2.41
35	Congenital nervous system abnormality	Enrichment	CEP290, CREBBP, PTEN, TSC2	2.36
36	Nervous system disease	Enrichment	CEP290, CREBBP, PTEN, TSC2	2.36
37	Autism spectrum disorder	Enrichment	HK1, PTEN, SETD2, TSC2	2.31
38	Dandy-walker syndrome	Enrichment	PDGFRB, SETD2	2.30
39	Myeloma, multiple	Enrichment	BAP1, CREBBP, KDM5C	2.29
40	Adenosine triphosphate, elevated, of erythrocytes	Enrichment	PKLR	2.20
41	Proteus syndrome	Enrichment	AKT1	2.20
42	Paget disease of bone 3	Enrichment	SQSTM1	2.20
43	Neu-laxova syndrome 1	Enrichment	PHGDH	2.20
44	Anemia, congenital, nonspherocytic hemolytic, 5	Enrichment	HK1	2.20
45	Anemia, congenital, nonspherocytic hemolytic, 2	Enrichment	PKLR	2.20
46	D-lactic aciduria with gout	Enrichment	LDHD	2.20
47	Phosphoglycerate kinase 1 deficiency	Enrichment	PGK1	2.20
48	Vacterl association with hydrocephalus	Enrichment	PTEN	2.20
49	Premature aging syndrome, penttinen type	Enrichment	PDGFRB	2.20
50	Phosphoglycerate dehydrogenase deficiency	Enrichment	PHGDH	2.20
51	Hypereosinophilic syndrome, idiopathic	Enrichment	PDGFRA	2.20
52	Stomatin-deficient cryohydrocytosis with neurologic defects	Enrichment	SLC2A1	2.20
53	Short qt syndrome 3	Enrichment	KCNJ2	2.20
54	Melanoma, uveal 2	Enrichment	BAP1	2.20
55	Glycogen storage disease xiii	Enrichment	ENO3	2.20
56	Basal ganglia calcification, idiopathic, 5	Enrichment	PDGFB	2.20
57	Short sleep, familial natural, 1	Enrichment	BHLHE41	2.20
58	Myofibromatosis, infantile, 1	Enrichment	PDGFRB	2.20
59	Triosephosphate isomerase deficiency	Enrichment	TPI1	2.20
60	Gist-plus syndrome	Enrichment	PDGFRA	2.20
61	Retinitis pigmentosa 79	Enrichment	HK1	2.20
62	Myopathy, distal, with rimmed vacuoles	Enrichment	SQSTM1	2.20
63	Frontotemporal dementia and/or amyotrophic lateral sclerosis 3	Enrichment	SQSTM1	2.20
64	Intellectual developmental disorder, autosomal dominant 70	Enrichment	SETD2	2.20
65	Acetyl-coa carboxylase-alpha deficiency	Enrichment	ACACA	2.20
66	Myeloid and lymphoid neoplasms associated with pdgfra rearrangement	Enrichment	PDGFRA	2.20
67	Phosphoserine aminotransferase deficiency	Enrichment	PSAT1	2.20
68	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	2.20
69	Papillary tumor of the pineal region	Enrichment	PTEN	2.20
70	Microvascular complications of diabetes 1	Enrichment	VEGFA	2.20
71	Camurati-engelmann disease 2	Enrichment	TGFB2	2.20
72	Neuropathy, hereditary motor and sensory, russe type	Enrichment	HK1	2.20
73	Neurodevelopmental disorder with visual defects and brain anomalies	Enrichment	HK1	2.20
74	Lactate dehydrogenase b deficiency	Enrichment	LDHB	2.20
75	Epilepsy, idiopathic generalized 12	Enrichment	SLC2A1	2.20
76	Basal ganglia calcification, idiopathic, 4	Enrichment	PDGFRB	2.20
77	Cowden syndrome 6	Enrichment	AKT1	2.20
78	Phosphoserine phosphatase deficiency	Enrichment	PSPH	2.20
79	Neurodevelopmental disorder with cardiomyopathy, spasticity, and brain abnormalities	Enrichment	SHMT2	2.20
80	Myeloid and lymphoid neoplasms associated with pdgfrb rearrangement	Enrichment	PDGFRB	2.20
81	Anemia, congenital, nonspherocytic hemolytic, 4	Enrichment	GPI	2.20
82	Atrial fibrillation, familial, 9	Enrichment	KCNJ2	2.20
83	Glioma susceptibility 2	Enrichment	PTEN	2.20
84	Kosaki overgrowth syndrome	Enrichment	PDGFRB	2.20
85	Loeys-dietz syndrome 5	Enrichment	TGFB3	2.20
86	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	2.20
87	Menke-hennekam syndrome 1	Enrichment	CREBBP	2.20
88	Ocular pterygium-digital keloid dysplasia syndrome	Enrichment	PDGFRB	2.20
89	Tufted angioma of skin	Enrichment	KDR	2.20
90	Luscan-lumish syndrome	Enrichment	SETD2	2.20
91	Neu-laxova syndrome 2	Enrichment	PSAT1	2.20
92	Rabin-pappas syndrome	Enrichment	SETD2	2.20
93	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	2.20
94	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	2.20
95	Epilepsy with myoclonic absences	Enrichment	SLC2A1	2.20
96	Menke-hennekam syndrome	Enrichment	CREBBP	2.20
97	Neurometabolic disorder due to serine deficiency	Enrichment	PSAT1	2.20
98	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	2.20
99	Silver-russell syndrome due to maternal uniparental disomy of chromosome 7	Enrichment	GRB10	2.20
100	Neu-laxova syndrome due to 3-phosphoserine phosphatase deficiency	Enrichment	PSPH	2.20
101	Male infertility due to obstructive azoospermia	Enrichment	PGK1	2.20
102	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	2.20
103	Hereditary cryohydrocytosis with reduced stomatin	Enrichment	SLC2A1	2.20
104	Retinal hemangioblastoma	Enrichment	VHL	2.20
105	Andersen cardiodysrhythmic periodic paralysis	Enrichment	KCNJ2	1.90
106	Myeloproliferative disorder, chronic, with eosinophilia	Enrichment	PDGFRB	1.90
107	Camurati-engelmann disease 1	Enrichment	TGFB1	1.90
108	Fanconi-bickel syndrome	Enrichment	LDHA	1.90
109	Fructose intolerance, hereditary	Enrichment	ALDOB	1.90
110	Glycogen storage disease vii	Enrichment	PFKM	1.90
111	Thumb deformity	Enrichment	CREBBP	1.90
112	Dystonia 9	Enrichment	SLC2A1	1.90
113	Dermatofibrosarcoma protuberans	Enrichment	PDGFB	1.90
114	Bruck syndrome 2	Enrichment	PLOD2	1.90
115	Welander distal myopathy	Enrichment	SQSTM1	1.90
116	Glut1 deficiency syndrome 1	Enrichment	SLC2A1	1.90
117	Congenital disorder of glycosylation, type it	Enrichment	PGM1	1.90
118	Angioma, tufted	Enrichment	KDR	1.90
119	Neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset	Enrichment	SQSTM1	1.90
120	Microcephaly 21, primary, autosomal recessive	Enrichment	GAPDH	1.90
121	Cebalid syndrome	Enrichment	MTOR	1.90
122	Menke-hennekam syndrome 2	Enrichment	EP300	1.90
123	Developmental and epileptic encephalopathy 88	Enrichment	MDH1	1.90
124	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.90
125	Infantile myofibromatosis	Enrichment	PDGFRB	1.90
126	Glucose transporter type 1 deficiency syndrome	Enrichment	SLC2A1	1.90
127	Glycogen storage disease xii	Enrichment	ALDOA	1.90
128	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	1.90
129	Camurati-engelmann disease	Enrichment	TGFB1	1.90
130	Ocular melanoma	Enrichment	BAP1	1.90
131	Paget's disease of bone	Enrichment	SQSTM1	1.90
132	Smith-kingsmore syndrome	Enrichment	MTOR	1.90
133	Kury-isidor syndrome	Enrichment	BAP1	1.90
134	Short femur	Enrichment	PLOD2	1.90
135	Chronic eosinophilic leukemia	Enrichment	PDGFRA	1.90
136	Vacterl with hydrocephalus	Enrichment	PTEN	1.90
137	Bruck syndrome	Enrichment	PLOD2	1.90
138	Acute leukemia of ambiguous lineage	Enrichment	VHL	1.90
139	B-lymphoblastic leukemia/lymphoma with recurrent genetic abnormality	Enrichment	PDGFRA	1.90
140	Juvenile polyposis of infancy	Enrichment	PTEN	1.90
141	Spastic paraplegia-paget disease of bone syndrome	Enrichment	SQSTM1	1.90
142	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	STAT3	1.73
143	Mesothelioma, malignant	Enrichment	BAP1	1.73
144	Myasthenic syndrome, congenital, 6, presynaptic	Enrichment	VHL	1.73
145	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	1.73
146	Intellectual developmental disorder, x-linked, syndromic, claes-jensen type	Enrichment	KDM5C	1.73
147	Glut1 deficiency syndrome 2	Enrichment	SLC2A1	1.73
148	Corneal dystrophy, posterior polymorphous, 3	Enrichment	ZEB1	1.73
149	Senior-loken syndrome 6	Enrichment	CEP290	1.73
150	Cleft soft palate	Enrichment	PLOD2	1.73
151	Corneal dystrophy, fuchs endothelial, 6	Enrichment	ZEB1	1.73
152	Joubert syndrome 5	Enrichment	CEP290	1.73
153	Meckel syndrome, type 6	Enrichment	CEP290	1.73
154	Tuberous sclerosis 2	Enrichment	TSC2	1.73
155	Neonatal nephrocutaneous inflammatory syndrome	Enrichment	EGFR	1.73
156	Tumor predisposition syndrome 1	Enrichment	BAP1	1.73
157	Primary polycythemia	Enrichment	VHL	1.73
158	Tethered spinal cord syndrome	Enrichment	CREBBP	1.73
159	Breast implant-associated anaplastic large cell lymphoma	Enrichment	STAT3	1.73
160	Hyper ige syndrome	Enrichment	STAT3	1.73
161	Chromosome 17q23.1-q23.2 deletion syndrome	Enrichment	SLC2A1	1.73
162	Xanthinuria, type ii	Enrichment	TSC2	1.73
163	Laryngeal squamous cell carcinoma	Enrichment	PTEN	1.73
164	Bap1 tumor predisposition syndrome	Enrichment	BAP1	1.73
165	Cog7-congenital disorder of glycosylation	Enrichment	CEP290	1.73
166	Occipital encephalocele	Enrichment	CEP290	1.73
167	Neonatal inflammatory skin and bowel disease	Enrichment	EGFR	1.73
168	Syndromic x-linked intellectual disability claes-jensen type	Enrichment	KDM5C	1.73
169	Enchondromatosis	Enrichment	HIF1A	1.73
170	Erythrocytosis, familial, 2	Enrichment	VHL	1.60
171	Paget disease of bone 2, early-onset	Enrichment	SQSTM1	1.60
172	Meckel syndrome, type 4	Enrichment	CEP290	1.60
173	Au-kline syndrome	Enrichment	VHL	1.60
174	Bardet-biedl syndrome 14	Enrichment	CEP290	1.60
175	Corneal dystrophy	Enrichment	ZEB1	1.60
176	Paget's disease of bone 2	Enrichment	SQSTM1	1.60
177	Vacterl association	Enrichment	CDH13	1.60
178	Glioma	Enrichment	PTEN	1.60
179	Clear cell papillary renal cell carcinoma	Enrichment	PBRM1	1.60
180	Enchondromatosis, multiple, ollier type	Enrichment	HIF1A	1.51
181	Arrhythmogenic right ventricular dysplasia, familial, 1	Enrichment	TGFB3	1.51
182	Fanconi anemia, complementation group d2	Enrichment	VHL	1.51
183	Vater/vacterl association	Enrichment	CDH13	1.51
184	Von hippel-lindau syndrome	Enrichment	VHL	1.51
185	Macrocephaly/autism syndrome	Enrichment	PTEN	1.51
186	Leber congenital amaurosis 10	Enrichment	CEP290	1.51
187	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.51
188	Pre-eclampsia	Enrichment	FLT1	1.51
189	Fuchs' endothelial dystrophy	Enrichment	ZEB1	1.51
190	Night blindness	Enrichment	CEP290	1.51
191	Hemangioma	Enrichment	PTEN	1.51
192	Arrhythmogenic right ventricular dysplasia 1	Enrichment	TGFB3	1.51
193	Acute megakaryocytic leukemia	Enrichment	PTEN	1.51
194	Congenital short qt syndrome	Enrichment	KCNJ2	1.51
195	West syndrome	Enrichment	SLC2A1, TSC2	1.51
196	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	TGFB2, TGFB3	1.51
197	Hereditary breast carcinoma	Enrichment	AKT1, PTEN	1.51
198	Atrial septal defect 1	Enrichment	TGFB2	1.43
199	Melanoma, uveal	Enrichment	BAP1	1.43
200	Corneal dystrophy, posterior polymorphous, 1	Enrichment	ZEB1	1.43
201	Hemangioma, capillary infantile	Enrichment	KDR	1.43
202	Renal dysplasia, cystic	Enrichment	CEP290	1.43
203	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.43
204	Keratoconus	Enrichment	TSC1	1.43
205	Hereditary spherocytosis	Enrichment	GPI	1.43
206	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	1.43
207	Breast adenocarcinoma	Enrichment	AKT1	1.43
208	Lung squamous cell carcinoma	Enrichment	EGFR	1.43
209	Hypertrichosis	Enrichment	CREBBP	1.43
210	Sporadic pheochromocytoma/secreting paraganglioma	Enrichment	VHL	1.43
211	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	1.37
212	Thyroid cancer, nonmedullary, 2	Enrichment	PTEN	1.37
213	Arima syndrome	Enrichment	CEP290	1.37
214	Gastrointestinal stromal tumor	Enrichment	PDGFRA	1.37
215	Polycystic kidney disease 1	Enrichment	TSC2	1.37
216	Follicular thyroid carcinoma	Enrichment	PTEN	1.37
217	Paroxysmal dystonia	Enrichment	SLC2A1	1.37
218	Overgrowth syndrome	Enrichment	MTOR	1.37
219	Glioma susceptibility 1	Enrichment	BAP1	1.31
220	Immunodeficiency 47	Enrichment	CEP290	1.31
221	Ewing sarcoma	Enrichment	BAP1	1.31
222	Alternating hemiplegia of childhood	Enrichment	SLC2A1	1.31
223	Permanent neonatal diabetes mellitus	Enrichment	STAT3	1.31
224	Charge syndrome	Enrichment	EP300	1.26
225	Myoclonic-atonic epilepsy	Enrichment	SLC2A1	1.26
226	Behavioral variant of frontotemporal dementia	Enrichment	SQSTM1	1.26
227	Marfan syndrome	Enrichment	TGFB2	1.22
228	Frontotemporal dementia and/or amyotrophic lateral sclerosis 1	Enrichment	SQSTM1	1.22
229	Melanoma	Enrichment	PTEN	1.22
230	Glycogen storage disease	Enrichment	PFKM	1.18
231	Lung non-small cell carcinoma	Enrichment	EGFR	1.18
232	Uterine corpus cancer	Enrichment	PTEN	1.18
233	Inherited isolated arrhythmogenic ventricular dysplasia, biventricular variant	Enrichment	TGFB3	1.14
234	Inherited isolated arrhythmogenic cardiomyopathy, dominant-left variant	Enrichment	TGFB3	1.14
235	Lip and oral cavity carcinoma	Enrichment	EGFR	1.14
236	Clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly	Enrichment	PLOD2	1.11
237	Senior-loken syndrome 1	Enrichment	CEP290	1.11
238	Acute promyelocytic leukemia	Enrichment	STAT3	1.11
239	Clubfoot	Enrichment	PLOD2	1.11
240	Breast cancer	Enrichment	AKT1, PTEN	1.10
241	Pheochromocytoma	Enrichment	VHL	1.07
242	Lung cancer susceptibility 3	Enrichment	EGFR	1.07
243	Heart disease	Enrichment	CREBBP	1.07
244	Cleft lip/palate	Enrichment	PDGFRA	1.07
245	Inherited isolated arrhythmogenic cardiomyopathy, dominant-right variant	Enrichment	TGFB3	1.07
246	Polydactyly, postaxial, type a1	Enrichment	EP300	1.05
247	Hydrocephalus	Enrichment	PDGFRB	1.05
248	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	1.05
249	Hydrocephalus, congenital, 1	Enrichment	SETD2	1.02
250	Rhabdomyosarcoma	Enrichment	PTEN	1.02
251	Gliosarcoma	Enrichment	EGFR	1.02
252	Melanoma, cutaneous malignant 1	Enrichment	BAP1	0.99
253	Congenital disorder of glycosylation, type in	Enrichment	PGM1	0.99
254	Giant cell glioblastoma	Enrichment	EGFR	0.99
255	Colorectal cancer	Enrichment	AKT1, EP300	0.99
256	Polycystic kidney disease	Enrichment	CEP290	0.97
257	Arteriovenous malformations of the brain	Enrichment	EGFR	0.95
258	Ehlers-danlos syndrome	Enrichment	TGFB2	0.95
259	Cardiomyopathy, dilated, 1a	Enrichment	RAPGEF5	0.91
260	Endometrial cancer	Enrichment	PTEN	0.91
261	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	VHL	0.91
262	Brittle bone disorder	Enrichment	PLOD2	0.87
263	Familial atrial fibrillation	Enrichment	KCNJ2	0.85
264	Scoliosis	Enrichment	CREBBP	0.85
265	Developmental and epileptic encephalopathy 1	Enrichment	SLC2A1	0.84
266	Tetralogy of fallot	Enrichment	KDR	0.82
267	Strabismus	Enrichment	SLC2A1	0.81
268	Prostate cancer	Enrichment	PTEN	0.78
269	Meckel syndrome, type 1	Enrichment	CEP290	0.78
270	Microcephaly	Enrichment	EP300, SLC2A1	0.74
271	Lung cancer	Enrichment	EGFR	0.74
272	Cystic fibrosis	Enrichment	TGFB1	0.74
273	Nephronophthisis	Enrichment	CEP290	0.73
274	Fanconi anemia, complementation group a	Enrichment	VHL	0.70
275	Cerebral palsy	Enrichment	PDGFRB	0.66
276	Epilepsy	Enrichment	SLC2A1	0.65
277	Benign epilepsy with centrotemporal spikes	Enrichment	SLC2A1	0.64
278	Bardet-biedl syndrome	Enrichment	CEP290	0.63
279	Centralopathic epilepsy	Enrichment	SLC2A1	0.62
280	Gastric cancer	Enrichment	PTEN	0.62
281	Joubert syndrome 1	Enrichment	CEP290	0.57
282	Spastic ataxia	Enrichment	CEP290	0.55
283	Hereditary breast ovarian cancer syndrome	Enrichment	PTEN	0.53
284	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	SQSTM1	0.51
285	Primary ovarian insufficiency	Enrichment	KDR	0.51
286	Cone-rod dystrophy 2	Enrichment	CEP290	0.46
287	Autism	Enrichment	CREBBP	0.44
288	Retinitis pigmentosa	Enrichment	CEP290, HK1	0.42
289	Leber plus disease	Enrichment	CEP290	0.35
290	Complex neurodevelopmental disorder	Enrichment	BAP1	0.27
291	Hereditary retinal dystrophy	Enrichment	CEP290, HK1	0.26
292	Fundus dystrophy	Enrichment	CEP290, HK1	0.26

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Clear cell renal cell carcinoma pathways

Pathway Network for Clear cell renal cell carcinoma pathways

Member Pathways for Clear cell renal cell carcinoma pathways

Pathways in the Clear cell renal cell carcinoma pathways SuperPath

Associated Genes for Clear cell renal cell carcinoma pathways

Associated Disorders for Clear cell renal cell carcinoma pathways

Disorders associated with Clear cell renal cell carcinoma pathways SuperPath

STRING Interaction Network for Clear cell renal cell carcinoma pathways

Sources for Clear cell renal cell carcinoma pathways