coenzyme A biosynthesis

Sources:

#	Name	Source	Genes
1	coenzyme A biosynthesis	PubChem	COASY PANK1 PANK2 PANK3 PPCDC PPCS (see all 6) (see less)
2	superpathway of coenzyme A biosynthesis III (mammals)	PubChem	COASY PANK1 PANK2 PANK3 PPCDC PPCS (see all 6) (see less)
3	coenzyme A biosynthesis II (eukaryotic)	PubChem	COASY PPCDC PPCS

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PPCS	Phosphopantothenoylcysteine Synthetase	Protein Coding	3
2	PPCDC	Phosphopantothenoylcysteine Decarboxylase	Protein Coding	3
3	COASY	Coenzyme A Synthase	Protein Coding	3
4	PANK3	Pantothenate Kinase 3	Protein Coding	2
5	PANK1	Pantothenate Kinase 1	Protein Coding	2
6	PANK2	Pantothenate Kinase 2	Protein Coding	2

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Neurodegeneration with brain iron accumulation 6	Enrichment	COASY	3.66
2	Pontocerebellar hypoplasia, type 12	Enrichment	COASY	3.66
3	Muscular lipidosis	Enrichment	COASY	3.66
4	Cardiomyopathy, dilated, 2c	Enrichment	PPCS	3.35
5	Neurodegeneration with brain iron accumulation 1	Enrichment	PANK2	2.75
6	Rubinstein-taybi syndrome 2	Enrichment	PANK2	2.66
7	Neurodegeneration with brain iron accumulation	Enrichment	COASY	2.66
8	Familial isolated dilated cardiomyopathy	Enrichment	PPCS	1.93
9	Dystonia	Enrichment	PANK2	1.81
10	Cone-rod dystrophy 2	Enrichment	PANK2	1.53
11	Retinitis pigmentosa	Enrichment	PANK2	1.04
12	Hereditary retinal dystrophy	Enrichment	PANK2	0.91
13	Fundus dystrophy	Enrichment	PANK2	0.91

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for coenzyme A biosynthesis