Condensation of Prometaphase Chromosomes
Pathways in the Condensation of Prometaphase Chromosomes SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Condensation of Prometaphase Chromosomes | Reactome |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | SMC4 | Structural Maintenance Of Chromosomes 4 | Protein Coding | 1 |
| 2 | SMC2 | Structural Maintenance Of Chromosomes 2 | Protein Coding | 1 |
| 3 | CSNK2A1 | Casein Kinase 2 Alpha 1 | Protein Coding | 1 |
| 4 | CSNK2A2 | Casein Kinase 2 Alpha 2 | Protein Coding | 1 |
| 5 | CSNK2B | Casein Kinase 2 Beta | Protein Coding | 1 |
| 6 | NCAPH | Non-SMC Condensin I Complex Subunit H | Protein Coding | 1 |
| 7 | NCAPG | Non-SMC Condensin I Complex Subunit G | Protein Coding | 1 |
| 8 | CCNB1 | Cyclin B1 | Protein Coding | 1 |
| 9 | CCNB2 | Cyclin B2 | Protein Coding | 1 |
| 10 | CDK1 | Cyclin Dependent Kinase 1 | Protein Coding | 1 |
| 11 | NCAPD2 | Non-SMC Condensin I Complex Subunit D2 | Protein Coding | 1 |
Disorders associated with Condensation of Prometaphase Chromosomes SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Okur-chung neurodevelopmental syndrome | Enrichment | CSNK2A1 | 3.09 |
| 2 | Microcephaly 23, primary, autosomal recessive | Enrichment | NCAPH | 3.09 |
| 3 | Craniodigital syndrome and intellectual disability syndrome | Enrichment | CSNK2B | 3.09 |
| 4 | Microcephaly 21, primary, autosomal recessive | Enrichment | NCAPD2 | 2.79 |
| 5 | Poirier-bienvenu neurodevelopmental syndrome | Enrichment | CSNK2B | 2.79 |
| 6 | Prognathism, mandibular | Enrichment | CSNK2B | 2.61 |
| 7 | Enophthalmos | Enrichment | CSNK2B | 2.49 |
| 8 | Syndactyly | Enrichment | CSNK2B | 2.49 |
| 9 | Autism spectrum disorder | Enrichment | CSNK2A1, CSNK2B | 2.47 |
| 10 | Autosomal dominant non-syndromic intellectual disability | Enrichment | CSNK2B | 1.40 |
| 11 | Complex neurodevelopmental disorder | Enrichment | CSNK2A1 | 1.02 |