Coregulation of Androgen receptor activity

No Pathway Network information available for Coregulation of Androgen receptor activity

Pathways in the Coregulation of Androgen receptor activity SuperPath

#	Name	Source	Genes
1	Coregulation of Androgen receptor activity	PubChem	AKT1 APPL1 AR BRCA1 CARM1 CASP8 CCND1 CCND3 CDK11B CDK6 CDKN2A CMTM2 CTDSP1 CTDSP2 CTNNB1 FHL2 FKBP4 GSN HIP1 HNRNPA1 KDM1A KDM3A KDM4C KLK2 KLK3 LATS2 MAK MED1 NCOA2 NCOA4 NCOA6 NKX3-1 NRIP1 PA2G4 PATZ1 PAWR PELP1 PIAS1 PIAS3 PIAS4 PRDX1 PRKDC PTK2B RANBP9 RPS6KA3 SNURF SRF SVIL TCF4 TGFB1I1 TGIF1 TMF1 TMPRSS2 UBA3 UBE2I UBE3A VAV3 XRCC5 XRCC6 ZMIZ1 ZNF318 (see all 61) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SVIL	Supervillin	Protein Coding	1
2	PA2G4	Proliferation-Associated 2G4	Protein Coding	1
3	PATZ1	POZ/BTB And AT Hook Containing Zinc Finger 1	Protein Coding	1
4	CMTM2	CKLF Like MARVEL Transmembrane Domain Containing 2	Protein Coding	1
5	NKX3-1	NK3 Homeobox 1	Protein Coding	1
6	SNURF	SNRPN Upstream Open Reading Frame	Protein Coding	1
7	KDM3A	Lysine Demethylase 3A	Protein Coding	1
8	MAK	Male Germ Cell Associated Kinase	Protein Coding	1
9	CDK11B	Cyclin Dependent Kinase 11B	Protein Coding	1
10	PAWR	Pro-Apoptotic WT1 Regulator	Protein Coding	1
11	CTDSP1	CTD Small Phosphatase 1	Protein Coding	1
12	RPS6KA3	Ribosomal Protein S6 Kinase A3	Protein Coding	1
13	KLK2	Kallikrein Related Peptidase 2	Protein Coding	1
14	ZMIZ1	Zinc Finger MIZ-Type Containing 1	Protein Coding	1
15	KLK3	Kallikrein Related Peptidase 3	Protein Coding	1
16	UBE3A	Ubiquitin Protein Ligase E3A	Protein Coding	1
17	TCF4	Transcription Factor 4	Protein Coding	1
18	TGIF1	TGFB Induced Factor Homeobox 1	Protein Coding	1
19	TGFB1I1	Transforming Growth Factor Beta 1 Induced Transcript 1	Protein Coding	1
20	ZNF318	Zinc Finger Protein 318	Protein Coding	1
21	NCOA4	Nuclear Receptor Coactivator 4	Protein Coding	1
22	TMPRSS2	Transmembrane Serine Protease 2	Protein Coding	1
23	PRDX1	Peroxiredoxin 1	Protein Coding	1
24	CTDSP2	CTD Small Phosphatase 2	Protein Coding	1
25	UBA3	Ubiquitin Like Modifier Activating Enzyme 3	Protein Coding	1
26	PIAS3	Protein Inhibitor Of Activated STAT 3	Protein Coding	1
27	CDK6	Cyclin Dependent Kinase 6	Protein Coding	1
28	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	1
29	PELP1	Proline, Glutamate And Leucine Rich Protein 1	Protein Coding	1
30	KDM4C	Lysine Demethylase 4C	Protein Coding	1
31	AR	Androgen Receptor	Protein Coding	1
32	NRIP1	Nuclear Receptor Interacting Protein 1	Protein Coding	1
33	FKBP4	FKBP Prolyl Isomerase 4	Protein Coding	1
34	CARM1	Coactivator Associated Arginine Methyltransferase 1	Protein Coding	1
35	SRF	Serum Response Factor	Protein Coding	1
36	LATS2	Large Tumor Suppressor Kinase 2	Protein Coding	1
37	CCND1	Cyclin D1	Protein Coding	1
38	HNRNPA1	Heterogeneous Nuclear Ribonucleoprotein A1	Protein Coding	1
39	XRCC5	X-Ray Repair Cross Complementing 5	Protein Coding	1
40	XRCC6	X-Ray Repair Cross Complementing 6	Protein Coding	1
41	GSN	Gelsolin	Protein Coding	1
42	APPL1	Adaptor Protein, Phosphotyrosine Interacting With PH Domain And Leucine Zipper 1	Protein Coding	1
43	CASP8	Caspase 8	Protein Coding	1
44	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
45	PIAS4	Protein Inhibitor Of Activated STAT 4	Protein Coding	1
46	FHL2	Four And A Half LIM Domains 2	Protein Coding	1
47	UBE2I	Ubiquitin Conjugating Enzyme E2 I	Protein Coding	1
48	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	1
49	VAV3	Vav Guanine Nucleotide Exchange Factor 3	Protein Coding	1
50	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	1
51	CTNNB1	Catenin Beta 1	Protein Coding	1
52	KDM1A	Lysine Demethylase 1A	Protein Coding	1
53	NCOA6	Nuclear Receptor Coactivator 6	Protein Coding	1
54	MED1	Mediator Complex Subunit 1	Protein Coding	1
55	CCND3	Cyclin D3	Protein Coding	1
56	NCOA2	Nuclear Receptor Coactivator 2	Protein Coding	1
57	RANBP9	RAN Binding Protein 9	Protein Coding	1
58	HIP1	Huntingtin Interacting Protein 1	Protein Coding	1
59	TMF1	TATA Element Modulatory Factor 1	Protein Coding	1
60	PIAS1	Protein Inhibitor Of Activated STAT 1	Protein Coding	1
61	PRKDC	Protein Kinase, DNA-Activated, Catalytic Subunit	Protein Coding	1

Disorders associated with Coregulation of Androgen receptor activity SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Ovarian cancer	Enrichment	AKT1, AR, BRCA1, CDKN2A, CTNNB1	4.05
2	Bladder cancer	Enrichment	BRCA1, CDKN2A, CTNNB1	3.54
3	Adrenocortical carcinoma	Enrichment	CDKN2A, CTNNB1	3.53
4	Colorectal cancer	Enrichment	AKT1, BRCA1, CCND1, CTNNB1	3.21
5	Adult hepatocellular carcinoma	Enrichment	CASP8, CTNNB1	3.15
6	Hepatocellular carcinoma	Enrichment	CASP8, CTNNB1	2.36
7	Palmoplantar keratoderma, punctate type ii	Enrichment	BRCA1	2.35
8	Proteus syndrome	Enrichment	AKT1	2.35
9	Prostate cancer, hereditary, x-linked 3	Enrichment	AR	2.35
10	Coffin-lowry syndrome	Enrichment	RPS6KA3	2.35
11	Androgen insensitivity, partial	Enrichment	AR	2.35
12	Caspase 8 deficiency	Enrichment	CASP8	2.35
13	Amyloidosis, finnish type	Enrichment	GSN	2.35
14	Holoprosencephaly 4	Enrichment	TGIF1	2.35
15	Microcephaly 12, primary, autosomal recessive	Enrichment	CDK6	2.35
16	Inclusion body myopathy with early-onset paget disease with or without frontotemporal dementia 3	Enrichment	HNRNPA1	2.35
17	Retinitis pigmentosa 62	Enrichment	MAK	2.35
18	Intellectual developmental disorder, x-linked 19	Enrichment	RPS6KA3	2.35
19	Infant-type hemispheric glioma	Enrichment	BRCA1	2.35
20	Myopathy, distal, 3	Enrichment	HNRNPA1	2.35
21	Immunodeficiency 26 with or without neurologic abnormalities	Enrichment	PRKDC	2.35
22	Cowden syndrome 6	Enrichment	AKT1	2.35
23	Cleft palate, psychomotor retardation, and distinctive facial features	Enrichment	KDM1A	2.35
24	Amyotrophic lateral sclerosis 20	Enrichment	HNRNPA1	2.35
25	Corneal dystrophy, fuchs endothelial, 3	Enrichment	TCF4	2.35
26	Congenital anomalies of kidney and urinary tract 3	Enrichment	NRIP1	2.35
27	Maturity-onset diabetes of the young, type 14	Enrichment	APPL1	2.35
28	Finnish upper limb-onset distal myopathy	Enrichment	HNRNPA1	2.35
29	Neurodevelopmental disorder with dysmorphic facies and distal skeletal anomalies	Enrichment	ZMIZ1	2.35
30	Adenoid ameloblastoma	Enrichment	CTNNB1	2.35
31	Cdkn2a cancer predisposition	Enrichment	CDKN2A	2.35
32	Palatal anomalies-widely spaced teeth-facial dysmorphism-developmental delay syndrome	Enrichment	KDM1A	2.35
33	Symptomatic form of coffin-lowry syndrome in female carriers	Enrichment	RPS6KA3	2.35
34	Relapsing-remitting multiple sclerosis	Enrichment	HNRNPA1	2.35
35	Acth-independent macronodular adrenal hyperplasia 3	Enrichment	KDM1A	2.35
36	Complete androgen insensitivity syndrome	Enrichment	AR	2.35
37	15q11q13 microduplication syndrome	Enrichment	UBE3A	2.35
38	Microcystic stromal tumor	Enrichment	CTNNB1	2.35
39	Primary peritoneal carcinoma	Enrichment	BRCA1	2.35
40	Breast cancer	Enrichment	AKT1, BRCA1, CASP8	2.33
41	Pancreatic cancer	Enrichment	BRCA1, CDKN2A	2.25
42	Prostate cancer	Enrichment	AR, BRCA1	2.13
43	Melanoma-astrocytoma syndrome	Enrichment	CDKN2A	2.05
44	Spinal and bulbar muscular atrophy, x-linked 1	Enrichment	AR	2.05
45	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	2.05
46	Melanoma, cutaneous malignant 2	Enrichment	CDKN2A	2.05
47	Myofibrillar myopathy 10	Enrichment	SVIL	2.05
48	Fanconi anemia, complementation group s	Enrichment	BRCA1	2.05
49	46,xy sex reversal 1	Enrichment	AR	2.05
50	Androgen insensitivity syndrome	Enrichment	AR	2.05
51	Pancreatic cancer 4	Enrichment	BRCA1	2.05
52	Hypospadias 1, x-linked	Enrichment	AR	2.05
53	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	2.05
54	Melanoma-pancreatic cancer syndrome	Enrichment	CDKN2A	2.05
55	Inflammatory breast carcinoma	Enrichment	BRCA1	2.05
56	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	2.05
57	Peritoneum cancer	Enrichment	BRCA1	2.05
58	Bilateral breast cancer	Enrichment	BRCA1	2.05
59	Posterior hypospadias	Enrichment	AR	2.05
60	Teratoma	Enrichment	CTNNB1	2.05
61	Angelman syndrome due to maternal 15q11q13 deletion	Enrichment	UBE3A	2.05
62	Malignant peritoneal mesothelioma	Enrichment	LATS2	2.05
63	Lung cancer	Enrichment	BRCA1, CASP8	2.04
64	Desmoid disease, hereditary	Enrichment	CTNNB1	1.87
65	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.87
66	Anus, imperforate	Enrichment	CTNNB1	1.87
67	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.87
68	Distal myopathy	Enrichment	HNRNPA1	1.87
69	Inclusion body myopathy with paget disease of bone and frontotemporal dementia	Enrichment	HNRNPA1	1.87
70	Desmoid tumor	Enrichment	CTNNB1	1.87
71	Cushing syndrome due to bilateral macronodular adrenocortical disease	Enrichment	KDM1A	1.87
72	Angelman syndrome due to imprinting defect in 15q11-q13	Enrichment	UBE3A	1.87
73	Gastric cancer	Enrichment	BRCA1, CDKN2A	1.80
74	Hereditary breast carcinoma	Enrichment	AKT1, BRCA1	1.78
75	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA1	1.75
76	Pitt-hopkins syndrome	Enrichment	TCF4	1.75
77	Pilomatrixoma	Enrichment	CTNNB1	1.75
78	Cholangiocarcinoma	Enrichment	BRCA1	1.75
79	Alazami syndrome	Enrichment	CTNNB1	1.75
80	Mantle cell lymphoma	Enrichment	CCND1	1.75
81	Craniopharyngioma	Enrichment	CTNNB1	1.75
82	Exudative vitreoretinopathy 1	Enrichment	CTNNB1	1.65
83	Von hippel-lindau syndrome	Enrichment	CCND1	1.65
84	Breast-ovarian cancer, familial 2	Enrichment	BRCA1	1.65
85	Cholangitis, primary sclerosing	Enrichment	TCF4	1.65
86	Fuchs' endothelial dystrophy	Enrichment	TCF4	1.65
87	Angelman syndrome	Enrichment	UBE3A	1.57
88	Li-fraumeni syndrome	Enrichment	CDKN2A	1.57
89	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.57
90	Breast adenocarcinoma	Enrichment	AKT1	1.57
91	Lung squamous cell carcinoma	Enrichment	CDKN2A	1.57
92	Gallbladder cancer	Enrichment	CTNNB1	1.51
93	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	CDKN2A	1.51
94	Gastroesophageal reflux	Enrichment	RPS6KA3	1.45
95	Spastic paraplegia 4, autosomal dominant	Enrichment	TCF4	1.45
96	Methylmalonic aciduria and homocystinuria, cblc type	Enrichment	PRDX1	1.45
97	Orthostatic intolerance	Enrichment	RPS6KA3	1.45
98	Exudative vitreoretinopathy	Enrichment	CTNNB1	1.45
99	Difference of sex development	Enrichment	AR	1.45
100	Ventricular septal defect	Enrichment	RPS6KA3	1.40
101	Cowden syndrome	Enrichment	AKT1	1.40
102	Leukemia, chronic lymphocytic	Enrichment	CCND1	1.36
103	Melanoma	Enrichment	CDKN2A	1.36
104	Leukemia, acute lymphoblastic	Enrichment	CDKN2A	1.32
105	46,xy complete gonadal dysgenesis	Enrichment	AR	1.32
106	Uterine corpus cancer	Enrichment	BRCA1	1.32
107	Specific learning disability	Enrichment	RPS6KA3	1.32
108	Epicanthus	Enrichment	TCF4	1.28
109	Meningioma	Enrichment	AKT1	1.28
110	Lip and oral cavity carcinoma	Enrichment	CDKN2A	1.28
111	Breast-ovarian cancer, familial 1	Enrichment	BRCA1	1.24
112	Stereotypic movement disorder	Enrichment	TCF4	1.24
113	Medulloblastoma	Enrichment	CTNNB1	1.21
114	Periventricular nodular heterotopia	Enrichment	BRCA1	1.21
115	Isolated macular dystrophy	Enrichment	MAK	1.21
116	Septopreoptic holoprosencephaly	Enrichment	TGIF1	1.18
117	Midline interhemispheric variant of holoprosencephaly	Enrichment	TGIF1	1.18
118	Rhabdomyosarcoma	Enrichment	BRCA1	1.16
119	Microform holoprosencephaly	Enrichment	TGIF1	1.16
120	Lobar holoprosencephaly	Enrichment	TGIF1	1.16
121	Melanoma, cutaneous malignant 1	Enrichment	CDKN2A	1.13
122	Polycystic liver disease	Enrichment	CTNNB1	1.13
123	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1	1.13
124	Alobar holoprosencephaly	Enrichment	TGIF1	1.13
125	Semilobar holoprosencephaly	Enrichment	TGIF1	1.11
126	Maturity-onset diabetes of the young	Enrichment	APPL1	1.06
127	Endometrial cancer	Enrichment	BRCA1	1.04
128	Hepatoblastoma	Enrichment	CTNNB1	1.04
129	Precursor t-cell acute lymphoblastic leukemia	Enrichment	CDKN2A	1.01
130	Microcephaly	Enrichment	CTNNB1, TCF4	0.98
131	Inherited cancer-predisposing syndrome	Enrichment	BRCA1, CDKN2A	0.93
132	Differentiated thyroid carcinoma	Enrichment	NCOA4	0.91
133	Primary autosomal recessive microcephaly	Enrichment	CDK6	0.87
134	Nephronophthisis	Enrichment	PIAS1	0.86
135	Male infertility	Enrichment	AR	0.85
136	Cakut	Enrichment	NRIP1	0.85
137	Fanconi anemia, complementation group a	Enrichment	BRCA1	0.84
138	Non-syndromic x-linked intellectual disability	Enrichment	RPS6KA3	0.82
139	Autosomal dominant non-syndromic intellectual disability	Enrichment	TCF4	0.69
140	Hypertelorism	Enrichment	RPS6KA3	0.68
141	Familial isolated dilated cardiomyopathy	Enrichment	FHL2	0.67
142	Hereditary breast ovarian cancer syndrome	Enrichment	BRCA1	0.66
143	Myeloma, multiple	Enrichment	CCND1	0.65
144	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	AR	0.65
145	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	HNRNPA1	0.64
146	Congenital nervous system abnormality	Enrichment	CTNNB1	0.42
147	Nervous system disease	Enrichment	CTNNB1	0.42
148	Autism spectrum disorder	Enrichment	TCF4	0.41
149	Complex neurodevelopmental disorder	Enrichment	ZMIZ1	0.37
150	Retinitis pigmentosa	Enrichment	MAK	0.21
151	Hereditary retinal dystrophy	Enrichment	MAK	0.13
152	Fundus dystrophy	Enrichment	MAK	0.13

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Coregulation of Androgen receptor activity

Pathway Network for Coregulation of Androgen receptor activity

Member Pathways for Coregulation of Androgen receptor activity

Pathways in the Coregulation of Androgen receptor activity SuperPath

Associated Genes for Coregulation of Androgen receptor activity

Associated Disorders for Coregulation of Androgen receptor activity

Disorders associated with Coregulation of Androgen receptor activity SuperPath

STRING Interaction Network for Coregulation of Androgen receptor activity

Sources for Coregulation of Androgen receptor activity