Cori cycle

No Pathway Network information available for Cori cycle

Pathways in the Cori cycle SuperPath

#	Name	Source	Genes
1	Cori cycle	WikiPathways	ALDOA G6PD GAPDH GPI GPT HK1 INS LDHA PFKP PGAM1 PGK1 PGK2 SLC2A1 SLC2A2 SLC2A4 TALDO1 TPI1 (see all 17) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ALDOA	Aldolase, Fructose-Bisphosphate A	Protein Coding	1
2	PGK2	Phosphoglycerate Kinase 2	Protein Coding	1
3	TPI1	Triosephosphate Isomerase 1	Protein Coding	1
4	TALDO1	Transaldolase 1	Protein Coding	1
5	SLC2A4	Solute Carrier Family 2 Member 4	Protein Coding	1
6	SLC2A2	Solute Carrier Family 2 Member 2	Protein Coding	1
7	SLC2A1	Solute Carrier Family 2 Member 1	Protein Coding	1
8	PGK1	Phosphoglycerate Kinase 1	Protein Coding	1
9	PGAM1	Phosphoglycerate Mutase 1	Protein Coding	1
10	PFKP	Phosphofructokinase, Platelet	Protein Coding	1
11	LDHA	Lactate Dehydrogenase A	Protein Coding	1
12	INS	Insulin	Protein Coding	1
13	HK1	Hexokinase 1	Protein Coding	1
14	GPT	Glutamic--Pyruvic Transaminase	Protein Coding	1
15	GPI	Glucose-6-Phosphate Isomerase	Protein Coding	1
16	GAPDH	Glyceraldehyde-3-Phosphate Dehydrogenase	Protein Coding	1
17	G6PD	Glucose-6-Phosphate Dehydrogenase	Protein Coding	1

Disorders associated with Cori cycle SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Fanconi-bickel syndrome	Enrichment	LDHA, SLC2A2	5.83
2	Type 2 diabetes mellitus	Enrichment	SLC2A2, SLC2A4	2.91
3	Anemia, congenital, nonspherocytic hemolytic, 5	Enrichment	HK1	2.90
4	Phosphoglycerate kinase 1 deficiency	Enrichment	PGK1	2.90
5	Stomatin-deficient cryohydrocytosis with neurologic defects	Enrichment	SLC2A1	2.90
6	Triosephosphate isomerase deficiency	Enrichment	TPI1	2.90
7	Retinitis pigmentosa 79	Enrichment	HK1	2.90
8	Neuropathy, hereditary motor and sensory, russe type	Enrichment	HK1	2.90
9	Neurodevelopmental disorder with visual defects and brain anomalies	Enrichment	HK1	2.90
10	Epilepsy, idiopathic generalized 12	Enrichment	SLC2A1	2.90
11	Anemia, congenital, nonspherocytic hemolytic, 4	Enrichment	GPI	2.90
12	Congenital nonspherocytic hemolytic anemia	Enrichment	G6PD	2.90
13	Epilepsy with myoclonic absences	Enrichment	SLC2A1	2.90
14	Male infertility due to obstructive azoospermia	Enrichment	PGK1	2.90
15	Hereditary cryohydrocytosis with reduced stomatin	Enrichment	SLC2A1	2.90
16	Dystonia 9	Enrichment	SLC2A1	2.60
17	Glut1 deficiency syndrome 1	Enrichment	SLC2A1	2.60
18	Maturity-onset diabetes of the young, type 10	Enrichment	INS	2.60
19	Hyperproinsulinemia	Enrichment	INS	2.60
20	Microcephaly 21, primary, autosomal recessive	Enrichment	GAPDH	2.60
21	Glucose transporter type 1 deficiency syndrome	Enrichment	SLC2A1	2.60
22	Glycogen storage disease xii	Enrichment	ALDOA	2.60
23	Transaldolase deficiency	Enrichment	TALDO1	2.60
24	Diabetes mellitus, permanent neonatal, 4	Enrichment	INS	2.60
25	Congenital hemolytic anemia	Enrichment	G6PD	2.60
26	Glucosephosphate dehydrogenase deficiency	Enrichment	G6PD	2.60
27	Type 1 diabetes mellitus 2	Enrichment	INS	2.43
28	Glut1 deficiency syndrome 2	Enrichment	SLC2A1	2.43
29	Chromosome 17q23.1-q23.2 deletion syndrome	Enrichment	SLC2A1	2.43
30	Neonatal diabetes mellitus	Enrichment	INS	2.30
31	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	G6PD	2.20
32	Type 1 diabetes mellitus	Enrichment	INS	2.13
33	Hereditary spherocytosis	Enrichment	GPI	2.13
34	Hemolytic anemia	Enrichment	GPI	2.06
35	Paroxysmal dystonia	Enrichment	SLC2A1	2.06
36	Alternating hemiplegia of childhood	Enrichment	SLC2A1	2.00
37	Permanent neonatal diabetes mellitus	Enrichment	INS	2.00
38	Coronary heart disease 5	Enrichment	G6PD	1.95
39	Myoclonic-atonic epilepsy	Enrichment	SLC2A1	1.95
40	Diabetes mellitus	Enrichment	INS	1.86
41	Congenital long qt syndrome	Enrichment	SLC2A2	1.83
42	Maturity-onset diabetes of the young	Enrichment	INS	1.61
43	Malaria	Enrichment	G6PD	1.55
44	Developmental and epileptic encephalopathy 1	Enrichment	SLC2A1	1.51
45	Strabismus	Enrichment	SLC2A1	1.48
46	Long qt syndrome 1	Enrichment	SLC2A2	1.43
47	Epilepsy	Enrichment	SLC2A1	1.31
48	Benign epilepsy with centrotemporal spikes	Enrichment	SLC2A1	1.30
49	Centralopathic epilepsy	Enrichment	SLC2A1	1.28
50	West syndrome	Enrichment	SLC2A1	1.27
51	Autism spectrum disorder	Enrichment	HK1	0.89
52	Microcephaly	Enrichment	SLC2A1	0.84
53	Retinitis pigmentosa	Enrichment	HK1	0.63
54	Hereditary retinal dystrophy	Enrichment	HK1	0.51
55	Fundus dystrophy	Enrichment	HK1	0.51

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Cori cycle

Member Pathways for Cori cycle

Pathways in the Cori cycle SuperPath

Associated Genes for Cori cycle

Associated Disorders for Cori cycle

Disorders associated with Cori cycle SuperPath

STRING Interaction Network for Cori cycle

Sources for Cori cycle