Creatine metabolism

Sources:

#	Name	Source	Genes
1	Creatine metabolism	Reactome	CKB CKM CKMT1A CKMT1B CKMT2 GAMT GATM SLC6A11 SLC6A12 SLC6A7 SLC6A8 (see all 11) (see less)
2	Creatine pathway	WikiPathways	CKB GAMT GATM OAT SLC6A8
3	creatine-phosphate biosynthesis	PubChem	CKB CKM CKMT1A CKMT1B CKMT2
4	creatine biosynthesis	PubChem	GAMT GATM

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CKB	Creatine Kinase B	Protein Coding	3
2	GAMT	Guanidinoacetate N-Methyltransferase	Protein Coding	3
3	GATM	Glycine Amidinotransferase	Protein Coding	3
4	CKM	Creatine Kinase, M-Type	Protein Coding	2
5	CKMT1B	Creatine Kinase, Mitochondrial 1B	Protein Coding	2
6	CKMT2	Creatine Kinase, Mitochondrial 2	Protein Coding	2
7	CKMT1A	Creatine Kinase, Mitochondrial 1A	Protein Coding	2
8	SLC6A8	Solute Carrier Family 6 Member 8	Protein Coding	2
9	SLC6A7	Solute Carrier Family 6 Member 7	Protein Coding	1
10	SLC6A11	Solute Carrier Family 6 Member 11	Protein Coding	1
11	SLC6A12	Solute Carrier Family 6 Member 12	Protein Coding	1
12	OAT	Ornithine Aminotransferase	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Fanconi renotubular syndrome 1	Enrichment	GATM	3.53
2	Cerebral creatine deficiency syndrome 2	Enrichment	GAMT	3.53
3	Cerebral creatine deficiency syndrome	Enrichment	GAMT	3.53
4	Cerebral creatine deficiency syndrome 3	Enrichment	GATM	3.53
5	Creatine deficiency disorders	Enrichment	GAMT	3.53
6	Cerebral creatine deficiency syndrome 1	Enrichment	SLC6A8	3.43
7	Choroid disease	Enrichment	OAT	3.43
8	Fanconi syndrome	Enrichment	GATM	3.35
9	Primary fanconi renotubular syndrome	Enrichment	GATM	3.23
10	Gyrate atrophy of choroid and retina	Enrichment	OAT	2.96
11	Pain disorder	Enrichment	OAT	2.66
12	Parkinson's disease	Enrichment	GAMT	2.55
13	Parkinson disease, late-onset	Enrichment	GAMT	2.45
14	Congenital nervous system abnormality	Enrichment	GAMT	1.81
15	Nervous system disease	Enrichment	GAMT	1.81
16	Optic atrophy plus syndrome	Enrichment	OAT	1.79
17	Hereditary retinal dystrophy	Enrichment	OAT	0.99
18	Fundus dystrophy	Enrichment	OAT	0.99

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Creatine metabolism