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CTNNB1 S33 mutants aren't phosphorylated
SuperPath
Pathway network
for
CTNNB1 S33 mutants aren't phosphorylated
SuperPath
16
Pathways
in the
CTNNB1 S33 mutants aren't phosphorylated
SuperPath
CTLA4 inhibitory signaling
Signaling by AMER1 mutants
Signaling by APC mutants
CTNNB1 S45 mutants aren't phosphorylated
APC truncation mutants have impaired AXIN binding
Signaling by WNT in cancer
CTNNB1 S37 mutants aren't phosphorylated
Disassembly of the destruction complex and recruitment of AXIN to the membrane
AXIN missense mutants destabilize the destruction complex
Signaling by GSK3beta mutants
CTNNB1 S33 mutants aren't phosphorylated
Signaling by CTNNB1 phospho-site mutants
CTNNB1 T41 mutants aren't phosphorylated
Truncations of AMER1 destabilize the destruction complex
Signaling by AXIN mutants
Beta-catenin phosphorylation cascade
58
Genes
in the
CTNNB1 S33 mutants aren't phosphorylated
SuperPath
PPP2CA
PPP2CB
PPP2R1A
PPP2R1B
PPP2R5A
PPP2R5B
PPP2R5C
PPP2R5D
PPP2R5E
AMER1
CSNK1A1
GSK3B
APC
AXIN1
CTNNB1
LRP6
LRP5
FZD5
WNT3A
FRAT1
FRAT2
AKT3
CTLA4
AKT1
AKT2
FYN
LCK
LYN
PTPN11
SRC
YES1
CD80
CD86
CTBP1
CTBP2
DKK1
DKK4
DKK2
RNF43
PORCN
TCF7L2
KREMEN2
TNKS2
FZD4
FZD6
FZD8
KREMEN1
TNKS
CSNK1G2
DVL1
DVL2
DVL3
FZD2
WNT1
WNT8A
WNT8B
FZD1
CAV1
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network
for
CTNNB1 S33 mutants aren't phosphorylated
SuperPath