Cytochrome c-mediated apoptotic response

Sources:

#	Name	Source	Genes
1	Cytochrome c-mediated apoptotic response	Reactome	CASP9 MAPK1 MAPK3 UACA
2	Regulation of the apoptosome activity	Reactome	CASP9 MAPK1 MAPK3 UACA
3	Formation of apoptosome	Reactome	CASP9 MAPK1 MAPK3 UACA

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	UACA	Uveal Autoantigen With Coiled-Coil Domains And Ankyrin Repeats	Protein Coding	3
2	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	3
3	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	3
4	CASP9	Caspase 9	Protein Coding	3

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome 13	Enrichment	MAPK1	3.53
2	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	2.93
3	Specific learning disability	Enrichment	MAPK1	2.49
4	Heart, malformation of	Enrichment	MAPK1	2.28
5	Microcephaly	Enrichment	MAPK1	1.45

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Cytochrome c-mediated apoptotic response