Cytokines and inflammatory response

No Pathway Network information available for Cytokines and inflammatory response

Pathways in the Cytokines and inflammatory response SuperPath

#	Name	Source	Genes
1	Cytokines and inflammatory response	WikiPathways	CD4 CSF1 CSF2 CSF3 CXCL1 CXCL2 HLA-DRA HLA-DRB1 IFN1@ IFNB1 IFNG IL10 IL11 IL12B IL13 IL15 IL1A IL1B IL2 IL3 IL4 IL5 IL6 IL7 PDGFA TGFB1 TNF TRA TRB (see all 29) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CD4	CD4 Molecule	Protein Coding	1
2	TNF	Tumor Necrosis Factor	Protein Coding	1
3	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
4	TRA	T Cell Receptor Alpha Locus	Protein Coding	1
5	PDGFA	Platelet Derived Growth Factor Subunit A	Protein Coding	1
6	IL15	Interleukin 15	Protein Coding	1
7	IL13	Interleukin 13	Protein Coding	1
8	IL12B	Interleukin 12B	Protein Coding	1
9	IL11	Interleukin 11	Protein Coding	1
10	IL10	Interleukin 10	Protein Coding	1
11	IL7	Interleukin 7	Protein Coding	1
12	IL6	Interleukin 6	Protein Coding	1
13	IL5	Interleukin 5	Protein Coding	1
14	IL4	Interleukin 4	Protein Coding	1
15	IL3	Interleukin 3	Protein Coding	1
16	IL2	Interleukin 2	Protein Coding	1
17	IL1B	Interleukin 1 Beta	Protein Coding	1
18	IL1A	Interleukin 1 Alpha	Protein Coding	1
19	IFNG	Interferon Gamma	Protein Coding	1
20	IFNB1	Interferon Beta 1	Protein Coding	1
21	HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	Protein Coding	1
22	HLA-DRA	Major Histocompatibility Complex, Class II, DR Alpha	Protein Coding	1
23	CXCL2	C-X-C Motif Chemokine Ligand 2	Protein Coding	1
24	CXCL1	C-X-C Motif Chemokine Ligand 1	Protein Coding	1
25	CSF3	Colony Stimulating Factor 3	Protein Coding	1
26	CSF2	Colony Stimulating Factor 2	Protein Coding	1
27	CSF1	Colony Stimulating Factor 1	Protein Coding	1
28	TRB	T Cell Receptor Beta Locus	Protein Coding	1
29	IFN1@	Interferon, Type 1, Cluster	Gene Cluster	1

Disorders associated with Cytokines and inflammatory response SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Systemic-onset juvenile idiopathic arthritis	Enrichment	HLA-DRB1, IL6	4.58
2	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10, TGFB1	4.18
3	Systemic lupus erythematosus	Enrichment	HLA-DRB1, IL10, TNF	4.12
4	Asthma	Enrichment	IL13, TNF	3.62
5	Human immunodeficiency virus type 1	Enrichment	IFNG, IL10	3.18
6	Precursor t-cell acute lymphoblastic leukemia	Enrichment	TRA, TRB	2.96
7	Immunodeficiency 69	Enrichment	IFNG	2.67
8	Immunodeficiency 130 with hpv-related verrucosis	Enrichment	IL7	2.67
9	Okt4 epitope deficiency	Enrichment	CD4	2.67
10	Graft-versus-host disease	Enrichment	IL10	2.67
11	Allergic rhinitis	Enrichment	IL13	2.67
12	Pulmonary alveolar proteinosis, acquired	Enrichment	HLA-DRB1	2.67
13	Immunodeficiency 29	Enrichment	IL12B	2.67
14	Graham little-piccardi-lassueur syndrome	Enrichment	HLA-DRA	2.67
15	Immunodeficiency 79	Enrichment	CD4	2.67
16	Camurati-engelmann disease 1	Enrichment	TGFB1	2.37
17	Sarcoidosis 1	Enrichment	HLA-DRB1	2.37
18	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	2.37
19	Immunodeficiency 127	Enrichment	TNF	2.37
20	Camurati-engelmann disease	Enrichment	TGFB1	2.37
21	Trypsinogen deficiency	Enrichment	TRB	2.37
22	Bullous pemphigoid	Enrichment	HLA-DRB1	2.37
23	Pediatric multiple sclerosis	Enrichment	HLA-DRB1	2.37
24	Takayasu arteritis	Enrichment	IL12B	2.19
25	Tuberous sclerosis 1	Enrichment	IFNG	2.19
26	Psoriatic arthritis	Enrichment	TNF	2.19
27	Hepatitis c virus	Enrichment	IFNG	2.19
28	Tuberous sclerosis 2	Enrichment	IFNG	2.19
29	Migraine without aura	Enrichment	TNF	2.19
30	Immunodeficiency 7	Enrichment	TRA	2.19
31	Vogt-koyanagi-harada disease	Enrichment	HLA-DRB1	2.19
32	Kaposi sarcoma	Enrichment	IL6	2.07
33	Temporal arteritis	Enrichment	HLA-DRB1	2.07
34	Cerebral malaria	Enrichment	TNF	2.07
35	Inherited epidermodysplasia verruciformis	Enrichment	IL7	2.07
36	Vitamin d-dependent rickets, type 2a	Enrichment	TRB	1.97
37	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.97
38	Narcolepsy 2	Enrichment	HLA-DRB1	1.97
39	Follicular lymphoma	Enrichment	HLA-DRB1	1.97
40	Vascular dementia	Enrichment	TNF	1.97
41	Diffuse cutaneous systemic sclerosis	Enrichment	HLA-DRB1	1.97
42	Idiopathic aplastic anemia	Enrichment	IFNG	1.97
43	Type 1 diabetes mellitus	Enrichment	IL6	1.89
44	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.89
45	Limited scleroderma	Enrichment	HLA-DRB1	1.89
46	Narcolepsy 1	Enrichment	HLA-DRB1	1.77
47	Rheumatoid arthritis	Enrichment	IL10	1.72
48	Inflammatory bowel disease 1	Enrichment	IL6	1.72
49	Aplastic anemia	Enrichment	IFNG	1.67
50	Alzheimer's disease	Enrichment	TNF	1.56
51	Multiple sclerosis	Enrichment	HLA-DRB1	1.53
52	Hereditary chronic pancreatitis	Enrichment	TRB	1.53
53	Pancreatitis, hereditary	Enrichment	TRB	1.45
54	Arteriovenous malformations of the brain	Enrichment	IL6	1.40
55	Behcet syndrome	Enrichment	IL10	1.40
56	Multisystem inflammatory syndrome in children	Enrichment	IFNB1	1.34
57	Malaria	Enrichment	TNF	1.32
58	Cystic fibrosis	Enrichment	TGFB1	1.18
59	Type 2 diabetes mellitus	Enrichment	IL6	1.07
60	Gastric cancer	Enrichment	IL1B	1.06
61	Breast cancer	Enrichment	IL2	0.83

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Cytokines and inflammatory response

Pathway Network for Cytokines and inflammatory response

Member Pathways for Cytokines and inflammatory response

Pathways in the Cytokines and inflammatory response SuperPath

Associated Genes for Cytokines and inflammatory response

Associated Disorders for Cytokines and inflammatory response

Disorders associated with Cytokines and inflammatory response SuperPath

STRING Interaction Network for Cytokines and inflammatory response

Sources for Cytokines and inflammatory response