Cytoprotection by HMOX1

No Pathway Network information available for Cytoprotection by HMOX1

Pathways in the Cytoprotection by HMOX1 SuperPath

#	Name	Source	Genes
1	Cytoprotection by HMOX1	Reactome	ABCC1 ALB BACH1 BLVRA BLVRB CARM1 CHD9 COX4I1 COX4I2 COX5A COX5B COX6A1 COX6A2 COX6B1 COX6B2 COX6C COX7A1 COX7A2 COX7A2L COX7B COX7C COX8A COX8C COXFA4 CREBBP FABP1 HBA1 HBA2 HBB HDAC3 HELZ2 HIGD1C HM13 HMOX1 HMOX2 MAFK MED1 MT-CO1 MT-CO2 MT-CO3 NCOA1 NCOA2 NCOA6 NCOR1 NCOR2 NFE2L2 NLRP3 PPARA PTK6 RXRA SIN3A SIN3B SMARCD3 STAP2 STAT3 TBL1X TBL1XR1 TGS1 TXNIP (see all 59) (see less)
2	Regulation of HMOX1 expression and activity	Reactome	BACH1 HM13 HMOX1 MAFK NFE2L2

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	HMOX1	Heme Oxygenase 1	Protein Coding	2
2	NFE2L2	NFE2 Like BZIP Transcription Factor 2	Protein Coding	2
3	BACH1	BACH Transcriptional Regulator 1	Protein Coding	2
4	MAFK	MAF BZIP Transcription Factor K	Protein Coding	2
5	HM13	Histocompatibility Minor 13	Protein Coding	2
6	CARM1	Coactivator Associated Arginine Methyltransferase 1	Protein Coding	1
7	NCOA2	Nuclear Receptor Coactivator 2	Protein Coding	1
8	TXNIP	Thioredoxin Interacting Protein	Protein Coding	1
9	NLRP3	NLR Family Pyrin Domain Containing 3	Protein Coding	1
10	COX6B2	Cytochrome C Oxidase Subunit 6B2	Protein Coding	1
11	COX4I1	Cytochrome C Oxidase Subunit 4I1	Protein Coding	1
12	COX5B	Cytochrome C Oxidase Subunit 5B	Protein Coding	1
13	COX6A1	Cytochrome C Oxidase Subunit 6A1	Protein Coding	1
14	COX6A2	Cytochrome C Oxidase Subunit 6A2	Protein Coding	1
15	COX6B1	Cytochrome C Oxidase Subunit 6B1	Protein Coding	1
16	COX6C	Cytochrome C Oxidase Subunit 6C	Protein Coding	1
17	COX7A1	Cytochrome C Oxidase Subunit 7A1	Protein Coding	1
18	COX7A2	Cytochrome C Oxidase Subunit 7A2	Protein Coding	1
19	COX7B	Cytochrome C Oxidase Subunit 7B	Protein Coding	1
20	COX7C	Cytochrome C Oxidase Subunit 7C	Protein Coding	1
21	COX8A	Cytochrome C Oxidase Subunit 8A	Protein Coding	1
22	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
23	ALB	Albumin	Protein Coding	1
24	FABP1	Fatty Acid Binding Protein 1	Protein Coding	1
25	NCOA6	Nuclear Receptor Coactivator 6	Protein Coding	1
26	SIN3B	SIN3 Transcription Regulator Family Member B	Protein Coding	1
27	SIN3A	SIN3 Transcription Regulator Family Member A	Protein Coding	1
28	HBA1	Hemoglobin Subunit Alpha 1	Protein Coding	1
29	HBA2	Hemoglobin Subunit Alpha 2	Protein Coding	1
30	HBB	Hemoglobin Subunit Beta	Protein Coding	1
31	HMOX2	Heme Oxygenase 2	Protein Coding	1
32	COX8C	Cytochrome C Oxidase Subunit 8C	Protein Coding	1
33	ABCC1	ATP Binding Cassette Subfamily C Member 1 (ABCC1 Blood Group)	Protein Coding	1
34	MT-CO1	Mitochondrially Encoded Cytochrome C Oxidase I	Protein Coding	1
35	MT-CO2	Mitochondrially Encoded Cytochrome C Oxidase II	Protein Coding	1
36	MT-CO3	Mitochondrially Encoded Cytochrome C Oxidase III	Protein Coding	1
37	COXFA4	Cytochrome C Oxidase Associated Subunit FA4	Protein Coding	1
38	PPARA	Peroxisome Proliferator Activated Receptor Alpha	Protein Coding	1
39	MED1	Mediator Complex Subunit 1	Protein Coding	1
40	STAP2	Signal Transducing Adaptor Family Member 2	Protein Coding	1
41	PTK6	Protein Tyrosine Kinase 6	Protein Coding	1
42	HIGD1C	HIG1 Hypoxia Inducible Domain Family Member 1C	Protein Coding	1
43	RXRA	Retinoid X Receptor Alpha	Protein Coding	1
44	BLVRA	Biliverdin Reductase A	Protein Coding	1
45	BLVRB	Biliverdin Reductase B	Protein Coding	1
46	SMARCD3	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit D3	Protein Coding	1
47	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	1
48	TBL1X	Transducin Beta Like 1 X-Linked	Protein Coding	1
49	TBL1XR1	TBL1X/Y Related 1	Protein Coding	1
50	CHD9	Chromodomain Helicase DNA Binding Protein 9	Protein Coding	1
51	COX4I2	Cytochrome C Oxidase Subunit 4I2	Protein Coding	1
52	HELZ2	Helicase With Zinc Finger 2	Protein Coding	1
53	NCOA1	Nuclear Receptor Coactivator 1	Protein Coding	1
54	HDAC3	Histone Deacetylase 3	Protein Coding	1
55	COX7A2L	Cytochrome C Oxidase Subunit 7A2 Like	Protein Coding	1
56	COX5A	Cytochrome C Oxidase Subunit 5A	Protein Coding	1
57	NCOR1	Nuclear Receptor Corepressor 1	Protein Coding	1
58	NCOR2	Nuclear Receptor Corepressor 2	Protein Coding	1
59	TGS1	Trimethylguanosine Synthase 1	Protein Coding	1

Disorders associated with Cytoprotection by HMOX1 SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Cox deficiency, benign infantile mitochondrial myopathy	Enrichment	COX4I1, COX5A, COX6A2, COX6B1, COX8A, MT-CO1, MT-CO2, MT-CO3	10.93
2	Mitochondrial complex iv deficiency, nuclear type 1	Enrichment	COX4I1, COX6B1, COX8A, MT-CO1, MT-CO2, MT-CO3	9.41
3	Methemoglobinemia, beta type	Enrichment	HBA1, HBA2, HBB	5.81
4	Autosomal dominant secondary polycythemia	Enrichment	HBA1, HBA2, HBB	5.81
5	Heinz body anemias	Enrichment	HBA1, HBA2, HBB	5.37
6	Heinz body anemia	Enrichment	HBA1, HBA2, HBB	5.37
7	Mitochondrial myopathy, infantile, transient	Enrichment	MT-CO1, MT-CO2, MT-CO3	5.19
8	Alpha-thalassemia	Enrichment	HBA1, HBA2, HBB	5.19
9	Mitochondrial myopathy with reversible cytochrome c oxidase deficiency	Enrichment	MT-CO1, MT-CO2, MT-CO3	5.04
10	Witteveen-kolk syndrome	Enrichment	SIN3A, SIN3B	4.73
11	Protein-deficiency anemia	Enrichment	HBA1, HBA2, HBB	4.66
12	Alpha thalassemia-intellectual disability syndrome type 1	Enrichment	HBA1, HBA2	4.25
13	Diffuse large b-cell lymphoma	Enrichment	CREBBP, STAT3, TBL1XR1	4.14
14	Erythrocytosis, familial, 7	Enrichment	HBA1, HBA2	3.95
15	Hemoglobin h disease	Enrichment	HBA1, HBA2	3.95
16	Hereditary recurrent myoglobinuria	Enrichment	MT-CO1, MT-CO3	3.95
17	Thalassemia	Enrichment	HBA2, HBB	3.73
18	Tetralogy of fallot	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.72
19	Mitochondrial complex v deficiency, mitochondrial type 1	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.72
20	Neuropathy, ataxia, and retinitis pigmentosa	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.72
21	Striatonigral degeneration, infantile, mitochondrial	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.72
22	Camptodactyly of fingers	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.72
23	Immunodeficiency, developmental delay, and hypohomocysteinemia	Enrichment	NFE2L2	3.43
24	Heme oxygenase 1 deficiency	Enrichment	HMOX1	3.43
25	Beta-thalassemia	Enrichment	HBA2, HBB	3.41
26	Beta-thalassemia major	Enrichment	HBA2, HBB	3.41
27	Leber hereditary optic neuropathy, modifier of	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.26
28	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.23
29	Familial colorectal cancer	Enrichment	MT-CO1, MT-CO2	3.09
30	Acute promyelocytic leukemia	Enrichment	STAT3, TBL1XR1	2.85
31	Hypertelorism	Enrichment	MT-CO1, MT-CO2, MT-CO3	2.83
32	Myeloma, multiple	Enrichment	CREBBP, NCOR2, RXRA	2.74
33	Leigh syndrome, nuclear	Enrichment	MT-CO1, MT-CO2, MT-CO3	2.48
34	Linear skin defects with multiple congenital anomalies 2	Enrichment	COX7B	2.36
35	Hypothyroidism, congenital, nongoitrous, 8	Enrichment	TBL1X	2.36
36	Myoglobinuria, recurrent	Enrichment	MT-CO1	2.36
37	Cinca syndrome	Enrichment	NLRP3	2.36
38	Keratoendotheliitis fugax hereditaria	Enrichment	NLRP3	2.36
39	Familial cold autoinflammatory syndrome 1	Enrichment	NLRP3	2.36
40	Hyperbiliverdinemia	Enrichment	BLVRA	2.36
41	Hyperthyroxinemia, familial dysalbuminemic	Enrichment	ALB	2.36
42	Muckle-wells syndrome	Enrichment	NLRP3	2.36
43	Mitochondrial complex iv deficiency, nuclear type 18	Enrichment	COX6A2	2.36
44	Deafness, autosomal dominant 34, with or without inflammation	Enrichment	NLRP3	2.36
45	Deafness, autosomal dominant 77	Enrichment	ABCC1	2.36
46	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	2.36
47	Exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis	Enrichment	COX4I2	2.36
48	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	2.36
49	Congenital analbuminemia	Enrichment	ALB	2.36
50	Mitochondrial complex iv deficiency, nuclear type 7	Enrichment	COX6B1	2.36
51	Mitochondrial complex iv deficiency, nuclear type 20	Enrichment	COX5A	2.36
52	Menke-hennekam syndrome 1	Enrichment	CREBBP	2.36
53	Mitochondrial complex iv deficiency, nuclear type 16	Enrichment	COX4I1	2.36
54	Mitochondrial complex iv deficiency, nuclear type 21	Enrichment	COXFA4	2.36
55	Mitochondrial complex iv deficiency, nuclear type 15	Enrichment	COX8A	2.36
56	Sickle cell-beta-thalassemia disease syndrome	Enrichment	HBB	2.36
57	Analbuminemia	Enrichment	ALB	2.36
58	Charcot-marie-tooth disease, recessive intermediate d	Enrichment	COX6A1	2.36
59	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	2.36
60	Pancreatic insufficiency-anemia-hyperostosis syndrome	Enrichment	COX4I2	2.36
61	Chromosome 15q24 deletion syndrome	Enrichment	SIN3A	2.36
62	Hemoglobin c-beta-thalassemia syndrome	Enrichment	HBB	2.36
63	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	2.36
64	Autosomal dominant spastic ataxia	Enrichment	MT-CO3	2.36
65	Sickle cell s-o arab disease	Enrichment	HBB	2.36
66	Sickle cell-beta zero-thalassemia	Enrichment	HBB	2.36
67	Menke-hennekam syndrome	Enrichment	CREBBP	2.36
68	Cryopyrin associated periodic syndrome	Enrichment	NLRP3	2.36
69	Familial amyloid nephropathy with urticaria and deafness	Enrichment	NLRP3	2.36
70	Sickle cell s-d punjab disease	Enrichment	HBB	2.36
71	Sickle cell s-c disease	Enrichment	HBB	2.36
72	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	2.36
73	Sickle cell s-e disease	Enrichment	HBB	2.36
74	Homozygous hemoglobin o arab disease	Enrichment	HBB	2.36
75	Sickle cell s-other specified hemoglobin variant	Enrichment	HBB	2.36
76	Leigh disease	Enrichment	MT-CO1, MT-CO2, MT-CO3	2.36
77	Pulmonary disease, chronic obstructive	Enrichment	HMOX1	2.32
78	Hydrops fetalis, nonimmune	Enrichment	HBA1, HBA2	2.25
79	Mitochondrial disease	Enrichment	MT-CO1, MT-CO2, MT-CO3	2.19
80	Leber plus disease	Enrichment	MT-CO1, MT-CO2, MT-CO3	2.09
81	Thumb deformity	Enrichment	CREBBP	2.06
82	Methemoglobinemia, alpha type	Enrichment	HBA1	2.06
83	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	2.06
84	Pericardial effusion	Enrichment	NLRP3	2.06
85	Hemoglobin lepore-beta-thalassemia syndrome	Enrichment	HBB	2.06
86	Sickle cell s-lepore disease	Enrichment	HBB	2.06
87	Lung cancer	Enrichment	NFE2L2	1.93
88	Cystic fibrosis	Enrichment	HMOX1	1.93
89	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	STAT3	1.89
90	Keratoderma, palmoplantar, with deafness	Enrichment	MT-CO1	1.89
91	Pierpont syndrome	Enrichment	TBL1XR1	1.89
92	Linear skin defects with multiple congenital anomalies 1	Enrichment	COX7B	1.89
93	Tethered spinal cord syndrome	Enrichment	CREBBP	1.89
94	Breast implant-associated anaplastic large cell lymphoma	Enrichment	STAT3	1.89
95	Hyper ige syndrome	Enrichment	STAT3	1.89
96	Hemoglobin e disease	Enrichment	HBB	1.89
97	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.89
98	Intellectual developmental disorder, autosomal dominant 41	Enrichment	TBL1XR1	1.89
99	Sickle cell-hemoglobin c disease	Enrichment	HBB	1.89
100	Hemoglobin d disease	Enrichment	HBB	1.89
101	Myelodysplastic syndrome with ring sideroblasts	Enrichment	MT-CO1	1.89
102	Delta beta-thalassemia	Enrichment	HBB	1.89
103	Unstable hemoglobin disease	Enrichment	HBB	1.89
104	Hemoglobin e/beta thalassemia disease	Enrichment	HBB	1.89
105	Ehlers-danlos syndrome, arthrochalasia type, 1	Enrichment	ALB	1.76
106	Sickle cell disease	Enrichment	HBB	1.76
107	Beta-thalassemia, dominant inclusion body type	Enrichment	HBB	1.76
108	Erythrocytosis, familial, 6	Enrichment	HBB	1.76
109	Beta-thalassemia intermedia	Enrichment	HBB	1.76
110	Hemoglobinopathy	Enrichment	HBB	1.76
111	Hemoglobin c disease	Enrichment	HBB	1.76
112	Hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome	Enrichment	HBB	1.76
113	Methemoglobinemia, beta-globin type	Enrichment	HBB	1.76
114	Hereditary persistence of fetal hemoglobin-sickle cell disease syndrome	Enrichment	HBB	1.67
115	Rubinstein-taybi syndrome 1	Enrichment	CREBBP	1.59
116	Deafness, nonsyndromic sensorineural, mitochondrial	Enrichment	MT-CO1	1.59
117	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP	1.59
118	Hypertrichosis	Enrichment	CREBBP	1.59
119	Hemolytic anemia	Enrichment	HBB	1.52
120	Colorectal cancer	Enrichment	NFE2L2	1.50
121	Fetal hemoglobin quantitative trait locus 1	Enrichment	HBB	1.46
122	Permanent neonatal diabetes mellitus	Enrichment	STAT3	1.46
123	Rare mitochondrial non-syndromic sensorineural deafness	Enrichment	MT-CO1	1.37
124	Heart disease	Enrichment	CREBBP	1.23
125	Corpus callosum, agenesis of	Enrichment	CREBBP	1.20
126	Atypical hemolytic-uremic syndrome	Enrichment	HBB	1.20
127	Isolated corpus callosum agenesis	Enrichment	CREBBP	1.20
128	Rare genetic intellectual disability	Enrichment	CREBBP	1.20
129	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP	1.20
130	Retinitis pigmentosa	Enrichment	MT-CO1, MT-CO2, MT-CO3	1.19
131	Arteriovenous malformations of the brain	Enrichment	NLRP3	1.10
132	Malaria	Enrichment	HBB	1.02
133	Autoinflammatory disease	Enrichment	NLRP3	1.00
134	Scoliosis	Enrichment	CREBBP	1.00
135	Non-immune hydrops fetalis	Enrichment	HBA2	0.90
136	Peripheral nervous system disease	Enrichment	COX6A1	0.88
137	Neuropathy	Enrichment	COX6A1	0.88
138	Epilepsy	Enrichment	MT-CO3	0.80
139	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ABCC1	0.69
140	Autism	Enrichment	CREBBP	0.57
141	Congenital nervous system abnormality	Enrichment	CREBBP	0.43
142	Nervous system disease	Enrichment	CREBBP	0.43

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Cytoprotection by HMOX1

Pathway Network for Cytoprotection by HMOX1

Member Pathways for Cytoprotection by HMOX1

Pathways in the Cytoprotection by HMOX1 SuperPath

Associated Genes for Cytoprotection by HMOX1

Associated Disorders for Cytoprotection by HMOX1

Disorders associated with Cytoprotection by HMOX1 SuperPath

STRING Interaction Network for Cytoprotection by HMOX1

Sources for Cytoprotection by HMOX1