Cytoskeleton remodeling_RalB regulation pathway

No Pathway Network information available for Cytoskeleton remodeling_RalB regulation pathway

Pathways in the Cytoskeleton remodeling_RalB regulation pathway SuperPath

#	Name	Source	Genes
1	Cytoskeleton remodeling_RalB regulation pathway	GeneGo (Thomson Reuters)	CALM1 CALM2 CALM3 EXOC2 EXOC8 HRAS PLCD1 RALB RALBP1 RALGDS REPS1 REPS2 RGL3 RIT1 (see all 14) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CALM1	Calmodulin 1	Protein Coding	1
2	CALM2	Calmodulin 2	Protein Coding	1
3	CALM3	Calmodulin 3	Protein Coding	1
4	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	1
5	PLCD1	Phospholipase C Delta 1	Protein Coding	1
6	RALB	RAS Like Proto-Oncogene B	Protein Coding	1
7	RALGDS	Ral Guanine Nucleotide Dissociation Stimulator	Protein Coding	1
8	RIT1	Ras Like Without CAAX 1	Protein Coding	1
9	REPS2	RALBP1 Associated Eps Domain Containing 2	Protein Coding	1
10	RALBP1	RalA Binding Protein 1	Protein Coding	1
11	EXOC2	Exocyst Complex Component 2	Protein Coding	1
12	RGL3	Ral Guanine Nucleotide Dissociation Stimulator Like 3	Protein Coding	1
13	REPS1	RALBP1 Associated Eps Domain Containing 1	Protein Coding	1
14	EXOC8	Exocyst Complex Component 8	Protein Coding	1

Disorders associated with Cytoskeleton remodeling_RalB regulation pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	7.31
2	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3	5.46
3	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, RIT1	3.99
4	Noonan syndrome 1	Enrichment	HRAS, RIT1	3.61
5	Hydrops fetalis, nonimmune	Enrichment	HRAS, RIT1	3.50
6	Rasopathy	Enrichment	HRAS, RIT1	3.50
7	Long qt syndrome	Enrichment	CALM1, CALM2	3.34
8	Non-immune hydrops fetalis	Enrichment	HRAS, RIT1	3.34
9	Nail disorder, nonsyndromic congenital, 3	Enrichment	PLCD1	2.99
10	Neurodegeneration with brain iron accumulation 7	Enrichment	REPS1	2.99
11	Long qt syndrome 16	Enrichment	CALM3	2.99
12	Neurodevelopmental disorder with microcephaly, seizures, and brain atrophy	Enrichment	EXOC8	2.99
13	Long qt syndrome 15	Enrichment	CALM2	2.99
14	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.99
15	Costello syndrome	Enrichment	HRAS	2.69
16	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	2.69
17	Noonan syndrome 8	Enrichment	RIT1	2.69
18	Long qt syndrome 14	Enrichment	CALM1	2.69
19	Neurodevelopmental disorder with dysmorphic facies and cerebellar hypoplasia	Enrichment	EXOC2	2.69
20	Wooly hair nevus	Enrichment	HRAS	2.69
21	Large congenital melanocytic nevus	Enrichment	HRAS	2.51
22	Spermatocytoma	Enrichment	HRAS	2.51
23	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS	2.38
24	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	RIT1	2.38
25	Epidermolytic nevus	Enrichment	HRAS	2.38
26	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	2.21
27	Nevus, epidermal	Enrichment	HRAS	2.14
28	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS	2.14
29	Noonan syndrome 3	Enrichment	HRAS	2.14
30	Follicular thyroid carcinoma	Enrichment	HRAS	2.14
31	Melanocytic nevus syndrome, congenital	Enrichment	HRAS	2.08
32	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	2.08
33	Arteriovenous malformation	Enrichment	HRAS	2.03
34	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS	1.99
35	Neurodegeneration with brain iron accumulation	Enrichment	REPS1	1.99
36	Lung non-small cell carcinoma	Enrichment	HRAS	1.95
37	Lip and oral cavity carcinoma	Enrichment	HRAS	1.91
38	Heart disease	Enrichment	RIT1	1.84
39	Rhabdomyosarcoma	Enrichment	HRAS	1.79
40	Sudden infant death syndrome	Enrichment	CALM2	1.76
41	Bladder cancer	Enrichment	HRAS	1.53
42	Differentiated thyroid carcinoma	Enrichment	HRAS	1.53
43	Hypertelorism	Enrichment	RIT1	1.28

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Cytoskeleton remodeling_RalB regulation pathway

Pathway Network for Cytoskeleton remodeling_RalB regulation pathway

Member Pathways for Cytoskeleton remodeling_RalB regulation pathway

Pathways in the Cytoskeleton remodeling_RalB regulation pathway SuperPath

Associated Genes for Cytoskeleton remodeling_RalB regulation pathway

Associated Disorders for Cytoskeleton remodeling_RalB regulation pathway

Disorders associated with Cytoskeleton remodeling_RalB regulation pathway SuperPath

STRING Interaction Network for Cytoskeleton remodeling_RalB regulation pathway

Sources for Cytoskeleton remodeling_RalB regulation pathway