Cytosolic iron-sulfur cluster assembly

No Pathway Network information available for Cytosolic iron-sulfur cluster assembly

Pathways in the Cytosolic iron-sulfur cluster assembly SuperPath

#	Name	Source	Genes
1	Cytosolic iron-sulfur cluster assembly	Reactome	ABCB7 BRIP1 CIAO1 CIAO2B CIAO3 CIAPIN1 ERCC2 MMS19 NDOR1 NUBP1 NUBP2 POLD1 RTEL1 (see all 13) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	NUBP2	NUBP Iron-Sulfur Cluster Assembly Factor 2, Cytosolic	Protein Coding	1
2	ERCC2	ERCC Excision Repair 2, TFIIH Core Complex Helicase Subunit	Protein Coding	1
3	ABCB7	ATP Binding Cassette Subfamily B Member 7	Protein Coding	1
4	NDOR1	NADPH Dependent Diflavin Oxidoreductase 1	Protein Coding	1
5	NUBP1	NUBP Iron-Sulfur Cluster Assembly Factor 1, Cytosolic	Protein Coding	1
6	CIAO2B	Cytosolic Iron-Sulfur Assembly Component 2B	Protein Coding	1
7	RTEL1	Regulator Of Telomere Elongation Helicase 1	Protein Coding	1
8	POLD1	DNA Polymerase Delta 1, Catalytic Subunit	Protein Coding	1
9	CIAPIN1	Cytokine Induced Apoptosis Inhibitor 1	Protein Coding	1
10	MMS19	MMS19 Cytosolic Iron-Sulfur Assembly Component	Protein Coding	1
11	CIAO3	Cytosolic Iron-Sulfur Assembly Component 3	Protein Coding	1
12	BRIP1	BRCA1 Interacting DNA Helicase 1	Protein Coding	1
13	CIAO1	Cytosolic Iron-Sulfur Assembly Component 1	Protein Coding	1

Disorders associated with Cytosolic iron-sulfur cluster assembly SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Pancreatic cancer	Enrichment	BRIP1, POLD1	3.60
2	Spinocerebellar ataxia, x-linked 6, with or without sideroblastic anemia	Enrichment	ABCB7	3.02
3	Fanconi anemia, complementation group j	Enrichment	BRIP1	3.02
4	Colorectal cancer 10	Enrichment	POLD1	3.02
5	Immunodeficiency 120	Enrichment	POLD1	3.02
6	Xeroderma pigmentosum, complementation group d	Enrichment	ERCC2	3.02
7	Cerebrooculofacioskeletal syndrome 2	Enrichment	ERCC2	3.02
8	Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome	Enrichment	POLD1	3.02
9	Xeroderma pigmentosum group d	Enrichment	ERCC2	3.02
10	X-linked sideroblastic anemia with ataxia	Enrichment	ABCB7	3.02
11	Dyskeratosis congenita, autosomal recessive 5	Enrichment	RTEL1	2.72
12	Multiple mitochondrial dysfunctions syndrome 10	Enrichment	CIAO1	2.72
13	Ovarian cancer 1	Enrichment	BRIP1	2.72
14	Autosomal dominant dyskeratosis congenita 4	Enrichment	RTEL1	2.72
15	Diffuse midline glioma, h3 k27m-mutant	Enrichment	BRIP1	2.72
16	Pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 3	Enrichment	RTEL1	2.72
17	Trichothiodystrophy 1, photosensitive	Enrichment	ERCC2	2.54
18	Dyskeratosis congenita, x-linked	Enrichment	RTEL1	2.54
19	Polymerase proofreading-related polyposis	Enrichment	POLD1	2.54
20	Colorectal cancer	Enrichment	BRIP1, POLD1	2.52
21	Epilepsy, progressive myoclonic, 4, with or without renal failure	Enrichment	RTEL1	2.42
22	Combined oxidative phosphorylation deficiency 24	Enrichment	RTEL1	2.42
23	Craniopharyngioma	Enrichment	ERCC2	2.42
24	Ovarian cancer	Enrichment	BRIP1, ERCC2	2.39
25	Fanconi anemia, complementation group d2	Enrichment	BRIP1	2.32
26	Xeroderma pigmentosum-cockayne syndrome complex	Enrichment	ERCC2	2.32
27	Cerebrooculofacioskeletal syndrome 1	Enrichment	ERCC2	2.24
28	Pulmonary fibrosis	Enrichment	RTEL1	2.24
29	Hoyeraal-hreidarsson syndrome	Enrichment	RTEL1	2.24
30	Inherited cancer-predisposing syndrome	Enrichment	BRIP1, POLD1	2.17
31	Tracheoesophageal fistula with or without esophageal atresia	Enrichment	BRIP1	2.07
32	Inflammatory bowel disease 1	Enrichment	ERCC2	2.07
33	Hypotrichosis simplex	Enrichment	ERCC2	2.07
34	Trichothiodystrophy	Enrichment	ERCC2	2.07
35	Isolated tracheo-esophageal fistula	Enrichment	BRIP1	2.02
36	Xeroderma pigmentosum, variant type	Enrichment	ERCC2	1.98
37	Combined immunodeficiency	Enrichment	POLD1	1.98
38	Combined t cell and b cell immunodeficiency	Enrichment	POLD1	1.98
39	Uterine corpus cancer	Enrichment	BRIP1	1.98
40	Familial colorectal cancer type x	Enrichment	POLD1	1.98
41	Combined t and b cell immunodeficiency	Enrichment	POLD1	1.98
42	Breast-ovarian cancer, familial 1	Enrichment	BRIP1	1.91
43	Corpus callosum, agenesis of	Enrichment	ERCC2	1.85
44	Isolated corpus callosum agenesis	Enrichment	ERCC2	1.85
45	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	ERCC2	1.85
46	Interstitial lung disease 2	Enrichment	RTEL1	1.79
47	Neuromuscular disease	Enrichment	CIAO1	1.77
48	Esophageal atresia/tracheoesophageal fistula	Enrichment	BRIP1	1.74
49	Dyskeratosis congenita	Enrichment	RTEL1	1.74
50	Leukodystrophy	Enrichment	ERCC2	1.72
51	Hepatoblastoma	Enrichment	ERCC2	1.70
52	Bladder cancer	Enrichment	ERCC2	1.56
53	Fanconi anemia, complementation group a	Enrichment	BRIP1	1.48
54	Leukemia, acute myeloid	Enrichment	RTEL1	1.42
55	Gastric cancer	Enrichment	BRIP1	1.39
56	Hereditary breast carcinoma	Enrichment	BRIP1	1.38
57	Hereditary breast ovarian cancer syndrome	Enrichment	BRIP1	1.29
58	Breast cancer	Enrichment	BRIP1	1.16

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Cytosolic iron-sulfur cluster assembly

Pathway Network for Cytosolic iron-sulfur cluster assembly

Member Pathways for Cytosolic iron-sulfur cluster assembly

Pathways in the Cytosolic iron-sulfur cluster assembly SuperPath

Associated Genes for Cytosolic iron-sulfur cluster assembly

Associated Disorders for Cytosolic iron-sulfur cluster assembly

Disorders associated with Cytosolic iron-sulfur cluster assembly SuperPath

STRING Interaction Network for Cytosolic iron-sulfur cluster assembly

Sources for Cytosolic iron-sulfur cluster assembly