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Cytosolic sensors of pathogen-associated DNA SuperPath

Pathway network for Cytosolic sensors of pathogen-associated DNA SuperPath
14 Pathways in the Cytosolic sensors of pathogen-associated DNA SuperPath
STING mediated induction of host immune responses Regulation of innate immune responses to cytosolic DNA
Regulation by TREX1 DEx/H-box helicases activate type I IFN and inflammatory cytokines production
Cytosolic DNA-sensing pathway ZBP1(DAI) mediated induction of type I IFNs
Selenium micronutrient network RIP-mediated NFkB activation via ZBP1
Cytosolic sensors of pathogen-associated DNA IRF3-mediated induction of type I IFN
IRF3 mediated activation of type 1 IFN LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
IkBA variant leads to EDA-ID STAT6-mediated induction of chemokines
103 Genes in the Cytosolic sensors of pathogen-associated DNA SuperPath
TBK1 IRF3 NFKB1 RELA TREX1 NLRP4 DTX4 STING1 ZBP1 NFKB2 IKBKG IKBKB
NFKBIA CHUK DDX41 DHX9 MYD88 RIPK1 RIPK3 NFKBIB CGAS NLRC3 XRCC6 IFI16
MRE11 PRKDC TRIM21 STAT6 XRCC5 IRF7 TICAM1 NKIRAS2 NKIRAS1 TLR3 TRIM32 RPS27A
UBA52 UBB UBC TRIM56 DHX36 POLR3GL POLR3F POLR3G POLR3C POLR2H POLR2K AIM2
POLR1C POLR2L POLR2E POLR2F POLR3D POLR3H POLR1D POLR3K POLR3E POLR3A POLR3B CREBBP
CTNNB1 EP300 LRRFIP1 IL33 CCL4 CCL5 TRIM25 TRADD FADD ATG12 ATG5 CCL4L2
ISG15 IKBKE PYCARD RIGI CASP10 ADAR CYLD IFNA1 IFNA2 IFNA4 IFNA5 IFNA6
IFNA7 IFNA8 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA21 IFNB1 IL1B IL6 IL18
CXCL10 CASP1 CASP8 RNF125 MAVS NLRX1 CRCP
*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.
STRING interaction network for Cytosolic sensors of pathogen-associated DNA SuperPath