D-myo-inositol-5-phosphate metabolism
Pathways in the D-myo-inositol-5-phosphate metabolism SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | D-myo-inositol-5-phosphate metabolism | PubChem |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | MTMR14 | Myotubularin Related Protein 14 | Protein Coding | 1 |
| 2 | PIP4P2 | Phosphatidylinositol-4,5-Bisphosphate 4-Phosphatase 2 | Protein Coding | 1 |
| 3 | MTMR3 | Myotubularin Related Protein 3 | Protein Coding | 1 |
| 4 | PIP4P1 | Phosphatidylinositol-4,5-Bisphosphate 4-Phosphatase 1 | Protein Coding | 1 |
| 5 | PIP4K2A | Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Alpha | Protein Coding | 1 |
| 6 | PLCE1 | Phospholipase C Epsilon 1 | Protein Coding | 1 |
| 7 | PLCD1 | Phospholipase C Delta 1 | Protein Coding | 1 |
| 8 | PLCB2 | Phospholipase C Beta 2 | Protein Coding | 1 |
| 9 | PLCG2 | Phospholipase C Gamma 2 | Protein Coding | 1 |
Disorders associated with D-myo-inositol-5-phosphate metabolism SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Nail disorder, nonsyndromic congenital, 3 | Enrichment | PLCD1 | 3.18 |
| 2 | Autoinflammation, antibody deficiency, and immune dysregulation | Enrichment | PLCG2 | 3.18 |
| 3 | Familial cold autoinflammatory syndrome 3 | Enrichment | PLCG2 | 3.18 |
| 4 | B-lymphoblastic leukemia/lymphoma with hyperdiploidy | Enrichment | PIP4K2A | 2.88 |
| 5 | Nephrotic syndrome, type 3 | Enrichment | PLCE1 | 2.70 |
| 6 | Myopathy, centronuclear, 1 | Enrichment | MTMR14 | 2.40 |
| 7 | Nephrotic syndrome, type 1 | Enrichment | PLCE1 | 2.22 |
| 8 | Focal segmental glomerulosclerosis | Enrichment | PLCE1 | 1.88 |
| 9 | Genetic steroid-resistant nephrotic syndrome | Enrichment | PLCE1 | 1.65 |
| 10 | Nephrotic syndrome | Enrichment | PLCE1 | 1.55 |
