D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis

Sources:

#	Name	Source	Genes
1	D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis	PubChem	IPMK ITPK1 MINPP1
2	D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis	PubChem	IPMK ITPK1
3	Synthesis of pyrophosphates in the cytosol	Reactome	ITPK1
4	Synthesis of IPs in the ER lumen	Reactome	MINPP1

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ITPK1	Inositol-Tetrakisphosphate 1-Kinase	Protein Coding	3
2	MINPP1	Multiple Inositol-Polyphosphate Phosphatase 1	Protein Coding	2
3	IPMK	Inositol Polyphosphate Multikinase	Protein Coding	2

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hereditary neuroendocrine tumor of small intestine	Enrichment	IPMK	3.83
2	Pontocerebellar hypoplasia, type 7	Enrichment	MINPP1	3.83
3	Pontocerebellar hypoplasia, type 16	Enrichment	MINPP1	3.66
4	Familial papillary or follicular thyroid carcinoma	Enrichment	MINPP1	3.66
5	Thyroid cancer, nonmedullary, 2	Enrichment	MINPP1	3.29
6	Follicular thyroid carcinoma	Enrichment	MINPP1	3.29
7	Pontocerebellar hypoplasia	Enrichment	MINPP1	2.88

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis