DDX1 as a regulatory component of the Drosha microprocessor

No Pathway Network information available for DDX1 as a regulatory component of the Drosha microprocessor

Pathways in the DDX1 as a regulatory component of the Drosha microprocessor SuperPath

#	Name	Source	Genes
1	DDX1 as a regulatory component of the Drosha microprocessor	WikiPathways	ATM DDX1 DGCR8 DROSHA MRE11 NBN RAD50 (see all 7) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	DGCR8	DGCR8 Microprocessor Complex Subunit	Protein Coding	1
2	ATM	ATM Serine/Threonine Kinase	Protein Coding	1
3	NBN	Nibrin	Protein Coding	1
4	MRE11	MRE11 Double Strand Break Repair Nuclease	Protein Coding	1
5	DROSHA	Drosha Ribonuclease III	Protein Coding	1
6	DDX1	DEAD-Box Helicase 1	Protein Coding	1
7	RAD50	RAD50 Double Strand Break Repair Protein	Protein Coding	1

Disorders associated with DDX1 as a regulatory component of the Drosha microprocessor SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hereditary breast ovarian cancer syndrome	Enrichment	ATM, DROSHA, MRE11, NBN, RAD50	10.53
2	Breast cancer	Enrichment	ATM, MRE11, NBN, RAD50	7.53
3	Ovarian cancer	Enrichment	ATM, MRE11, NBN, RAD50	7.00
4	Inherited cancer-predisposing syndrome	Enrichment	ATM, MRE11, NBN, RAD50	6.53
5	Hereditary breast carcinoma	Enrichment	ATM, NBN, RAD50	5.96
6	Nijmegen breakage syndrome-like disorder	Enrichment	MRE11, RAD50	5.86
7	Colonic benign neoplasm	Enrichment	ATM, MRE11	5.09
8	Breast-ovarian cancer, familial 1	Enrichment	ATM, NBN	4.75
9	Hepatocellular carcinoma	Enrichment	NBN, RAD50	4.28
10	Pancreatic cancer	Enrichment	ATM, NBN	4.17
11	Prostate cancer	Enrichment	ATM, NBN	4.04
12	Gastric cancer	Enrichment	ATM, NBN	3.69
13	Ataxia-telangiectasia-like disorder 1	Enrichment	MRE11	3.29
14	Endometrial serous adenocarcinoma	Enrichment	ATM	3.29
15	B-cell non-hodgkin lymphoma	Enrichment	ATM	3.29
16	Cardiac valvular dysplasia, x-linked	Enrichment	ATM	2.99
17	Pineoblastoma	Enrichment	DROSHA	2.99
18	High grade glioma	Enrichment	ATM	2.99
19	T-cell prolymphocytic leukemia	Enrichment	ATM	2.99
20	Ataxia-telangiectasia	Enrichment	ATM	2.81
21	Nijmegen breakage syndrome	Enrichment	NBN	2.81
22	Polycythemia vera	Enrichment	ATM	2.81
23	Koolen-de vries syndrome	Enrichment	ATM	2.81
24	Adenocarcinoma	Enrichment	ATM	2.81
25	Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia	Enrichment	MRE11	2.69
26	Mantle cell lymphoma	Enrichment	ATM	2.69
27	Oculomotor apraxia	Enrichment	ATM	2.69
28	Glioblastoma	Enrichment	ATM	2.59
29	Clear cell renal cell carcinoma	Enrichment	ATM	2.51
30	Renal cell carcinoma, papillary, 1	Enrichment	ATM	2.44
31	Lynch syndrome 1	Enrichment	ATM	2.29
32	Leukemia, chronic lymphocytic	Enrichment	ATM	2.29
33	Aplastic anemia	Enrichment	NBN	2.29
34	Immune deficiency disease	Enrichment	ATM	2.25
35	Leukemia, acute lymphoblastic	Enrichment	NBN	2.25
36	Uterine corpus cancer	Enrichment	ATM	2.25
37	Familial colorectal cancer type x	Enrichment	ATM	2.25
38	Premature menopause	Enrichment	NBN	2.17
39	Renal cell carcinoma, nonpapillary	Enrichment	ATM	2.11
40	Gliosarcoma	Enrichment	ATM	2.08
41	Giant cell glioblastoma	Enrichment	ATM	2.06
42	Diffuse large b-cell lymphoma	Enrichment	NBN	2.01
43	Endometrial cancer	Enrichment	ATM	1.97
44	Lissencephaly	Enrichment	NBN	1.97
45	Bladder cancer	Enrichment	ATM	1.83
46	Myeloma, multiple	Enrichment	ATM	1.54
47	Primary ovarian insufficiency	Enrichment	NBN	1.52
48	Colorectal cancer	Enrichment	ATM	1.36
49	Microcephaly	Enrichment	NBN	1.21

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

DDX1 as a regulatory component of the Drosha microprocessor

Pathway Network for DDX1 as a regulatory component of the Drosha microprocessor

Member Pathways for DDX1 as a regulatory component of the Drosha microprocessor

Pathways in the DDX1 as a regulatory component of the Drosha microprocessor SuperPath

Associated Genes for DDX1 as a regulatory component of the Drosha microprocessor

Associated Disorders for DDX1 as a regulatory component of the Drosha microprocessor

Disorders associated with DDX1 as a regulatory component of the Drosha microprocessor SuperPath

STRING Interaction Network for DDX1 as a regulatory component of the Drosha microprocessor

Sources for DDX1 as a regulatory component of the Drosha microprocessor