Dectin-2 family

No Pathway Network information available for Dectin-2 family

Pathways in the Dectin-2 family SuperPath

#	Name	Source	Genes
1	Dectin-2 family	Reactome	CLEC10A CLEC4A CLEC4C CLEC4D CLEC4E CLEC6A FCER1G FYN LYN MUC1 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3A MUC4 MUC5AC MUC5B MUC6 MUC7 MUCL1 PLCG2 SYK (see all 28) (see less)
2	Termination of O-glycan biosynthesis	Reactome	MUC1 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3A MUC4 MUC5AC MUC5B MUC6 MUC7 MUCL1 ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST6GAL1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 (see all 25) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	MUC12	Mucin 12, Cell Surface Associated	Protein Coding	2
2	MUCL1	Mucin Like 1	Protein Coding	2
3	MUC17	Mucin 17, Cell Surface Associated	Protein Coding	2
4	MUC15	Mucin 15, Cell Surface Associated	Protein Coding	2
5	MUC20	Mucin 20, Cell Surface Associated	Protein Coding	2
6	MUC19	Mucin 19, Oligomeric (Gene/Pseudogene)	Protein Coding	2
7	MUC21	Mucin 21, Cell Surface Associated	Protein Coding	2
8	MUC1	Mucin 1, Cell Surface Associated	Protein Coding	2
9	MUC2	Mucin 2, Oligomeric Mucus/Gel-Forming	Protein Coding	2
10	MUC3A	Mucin 3A, Cell Surface Associated	Protein Coding	2
11	MUC4	Mucin 4, Cell Surface Associated	Protein Coding	2
12	MUC5AC	Mucin 5AC, Oligomeric Mucus/Gel-Forming	Protein Coding	2
13	MUC6	Mucin 6, Oligomeric Mucus/Gel-Forming (Gene/Pseudogene)	Protein Coding	2
14	MUC7	Mucin 7, Secreted	Protein Coding	2
15	MUC13	Mucin 13, Cell Surface Associated	Protein Coding	2
16	MUC5B	Mucin 5B, Oligomeric Mucus/Gel-Forming	Protein Coding	2
17	MUC16	Mucin 16, Cell Surface Associated	Protein Coding	2
18	CLEC10A	C-Type Lectin Domain Containing 10A	Protein Coding	1
19	CLEC4C	C-Type Lectin Domain Family 4 Member C	Protein Coding	1
20	FCER1G	Fc Epsilon Receptor Ig	Protein Coding	1
21	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
22	CLEC4E	C-Type Lectin Domain Family 4 Member E	Protein Coding	1
23	CLEC4D	C-Type Lectin Domain Family 4 Member D	Protein Coding	1
24	LYN	LYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
25	CLEC4A	C-Type Lectin Domain Family 4 Member A	Protein Coding	1
26	PLCG2	Phospholipase C Gamma 2	Protein Coding	1
27	SYK	Spleen Associated Tyrosine Kinase	Protein Coding	1
28	CLEC6A	C-Type Lectin Domain Containing 6A	Protein Coding	1
29	ST6GALNAC2	ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 2	Protein Coding	1
30	ST6GALNAC3	ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 3	Protein Coding	1
31	ST6GALNAC4	ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 4	Protein Coding	1
32	ST6GAL1	ST6 Beta-Galactoside Alpha-2,6-Sialyltransferase 1	Protein Coding	1
33	ST3GAL1	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 1	Protein Coding	1
34	ST3GAL2	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 2	Protein Coding	1
35	ST3GAL4	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 4	Protein Coding	1
36	ST3GAL3	ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 3	Protein Coding	1

Disorders associated with Dectin-2 family SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Tubulointerstitial kidney disease, autosomal dominant 2	Enrichment	MUC1	2.73
2	Intellectual developmental disorder, autosomal recessive 12	Enrichment	ST3GAL3	2.73
3	Extrinsic allergic alveolitis	Enrichment	MUC5B	2.73
4	St3gal3-cdg	Enrichment	ST3GAL3	2.73
5	Immunodeficiency 82 with systemic inflammation	Enrichment	SYK	2.69
6	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	2.69
7	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	2.69
8	Autoinflammatory disease, systemic, with vasculitis	Enrichment	LYN	2.69
9	Colitis	Enrichment	SYK	2.69
10	Panbronchiolitis, diffuse	Enrichment	MUC5B	2.43
11	Developmental and epileptic encephalopathy 15	Enrichment	ST3GAL3	2.43
12	Arthritis	Enrichment	SYK	2.38
13	Pulmonary fibrosis	Enrichment	MUC5B	1.96
14	Asthma	Enrichment	MUC7	1.70
15	Immune deficiency disease	Enrichment	SYK	1.65
16	Interstitial lung disease 2	Enrichment	MUC5B	1.51
17	Severe covid-19	Enrichment	MUC5B	1.28
18	Developmental and epileptic encephalopathy	Enrichment	ST3GAL3	1.19
19	Ovarian cancer	Enrichment	MUC16	0.77

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Dectin-2 family

Member Pathways for Dectin-2 family

Pathways in the Dectin-2 family SuperPath

Associated Genes for Dectin-2 family

Associated Disorders for Dectin-2 family

Disorders associated with Dectin-2 family SuperPath

STRING Interaction Network for Dectin-2 family

Sources for Dectin-2 family