Defective DNA double strand break response due to BARD1 loss of function

No Pathway Network information available for Defective DNA double strand break response due to BARD1 loss of function

#	Name	Source	Genes
1	Defective DNA double strand break response due to BARD1 loss of function	Reactome	BARD1 BRCA1
2	Defective DNA double strand break response due to BRCA1 loss of function	Reactome	BARD1 BRCA1

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	BARD1	BRCA1 Associated RING Domain 1	Protein Coding	2
2	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	2

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Endometrial cancer	Enrichment	BARD1, BRCA1	5.64
2	Gastric cancer	Enrichment	BARD1, BRCA1	5.01
3	Hereditary breast carcinoma	Enrichment	BARD1, BRCA1	4.99
4	Hereditary breast ovarian cancer syndrome	Enrichment	BARD1, BRCA1	4.79
5	Breast cancer	Enrichment	BARD1, BRCA1	4.52
6	Ovarian cancer	Enrichment	BARD1, BRCA1	4.26
7	Inherited cancer-predisposing syndrome	Enrichment	BARD1, BRCA1	4.03
8	Palmoplantar keratoderma, punctate type ii	Enrichment	BRCA1	3.83
9	Infant-type hemispheric glioma	Enrichment	BRCA1	3.83
10	Primary peritoneal carcinoma	Enrichment	BRCA1	3.83
11	Fanconi anemia, complementation group s	Enrichment	BRCA1	3.53
12	Pancreatic cancer 4	Enrichment	BRCA1	3.53
13	Inflammatory breast carcinoma	Enrichment	BRCA1	3.53
14	Peritoneum cancer	Enrichment	BRCA1	3.53
15	Bilateral breast cancer	Enrichment	BRCA1	3.53
16	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA1	3.23
17	Cholangiocarcinoma	Enrichment	BRCA1	3.23
18	Breast-ovarian cancer, familial 2	Enrichment	BRCA1	3.13
19	Uterine corpus cancer	Enrichment	BRCA1	2.79
20	Breast-ovarian cancer, familial 1	Enrichment	BRCA1	2.72
21	Periventricular nodular heterotopia	Enrichment	BRCA1	2.69
22	Rhabdomyosarcoma	Enrichment	BRCA1	2.63
23	Hepatoblastoma	Enrichment	BARD1	2.51
24	Pancreatic cancer	Enrichment	BRCA1	2.43
25	Bladder cancer	Enrichment	BRCA1	2.37
26	Prostate cancer	Enrichment	BRCA1	2.37
27	Lung cancer	Enrichment	BRCA1	2.33
28	Fanconi anemia, complementation group a	Enrichment	BRCA1	2.29
29	Myeloma, multiple	Enrichment	BARD1	2.08
30	Colorectal cancer	Enrichment	BRCA1	1.89

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Defective DNA double strand break response due to BARD1 loss of function