Development and heterogeneity of the ILC family

No Pathway Network information available for Development and heterogeneity of the ILC family

Pathways in the Development and heterogeneity of the ILC family SuperPath

#	Name	Source	Genes
1	Development and heterogeneity of the ILC family	WikiPathways	AHR AREG BCL11B EOMES GATA3 GFI1 HNF1A ID2 IFNG IL12A IL12B IL13 IL15 IL17A IL18 IL1B IL22 IL23A IL25 IL33 IL4 IL5 IL6 IL7 IL9 NFIL3 RORA TBX21 TNF TOX TSLP ZBTB16 (see all 32) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	IL33	Interleukin 33	Protein Coding	1
2	TSLP	Thymic Stromal Lymphopoietin	Protein Coding	1
3	EOMES	Eomesodermin	Protein Coding	1
4	ZBTB16	Zinc Finger And BTB Domain Containing 16	Protein Coding	1
5	TNF	Tumor Necrosis Factor	Protein Coding	1
6	HNF1A	HNF1 Homeobox A	Protein Coding	1
7	BCL11B	BCL11 Transcription Factor B	Protein Coding	1
8	RORA	RAR Related Orphan Receptor A	Protein Coding	1
9	IL23A	Interleukin 23 Subunit Alpha	Protein Coding	1
10	IL22	Interleukin 22	Protein Coding	1
11	NFIL3	Nuclear Factor, Interleukin 3 Regulated	Protein Coding	1
12	AREG	Amphiregulin	Protein Coding	1
13	IL18	Interleukin 18	Protein Coding	1
14	IL17A	Interleukin 17A	Protein Coding	1
15	IL15	Interleukin 15	Protein Coding	1
16	IL13	Interleukin 13	Protein Coding	1
17	IL12B	Interleukin 12B	Protein Coding	1
18	IL12A	Interleukin 12A	Protein Coding	1
19	IL9	Interleukin 9	Protein Coding	1
20	IL7	Interleukin 7	Protein Coding	1
21	IL6	Interleukin 6	Protein Coding	1
22	IL5	Interleukin 5	Protein Coding	1
23	IL4	Interleukin 4	Protein Coding	1
24	IL1B	Interleukin 1 Beta	Protein Coding	1
25	IFNG	Interferon Gamma	Protein Coding	1
26	ID2	Inhibitor Of DNA Binding 2	Protein Coding	1
27	TBX21	T-Box Transcription Factor 21	Protein Coding	1
28	GFI1	Growth Factor Independent 1 Transcriptional Repressor	Protein Coding	1
29	GATA3	GATA Binding Protein 3	Protein Coding	1
30	AHR	Aryl Hydrocarbon Receptor	Protein Coding	1
31	TOX	Thymocyte Selection Associated High Mobility Group Box	Protein Coding	1
32	IL25	Interleukin 25	Protein Coding	1

Disorders associated with Development and heterogeneity of the ILC family SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Type 1 diabetes mellitus	Enrichment	HNF1A, IL6	4.09
2	Asthma	Enrichment	IL13, TNF	3.53
3	Hepatic adenomas, familial	Enrichment	HNF1A	2.63
4	Skeletal defects, genital hypoplasia, and impaired intellectual development	Enrichment	ZBTB16	2.63
5	Immunodeficiency 49, severe combined	Enrichment	BCL11B	2.63
6	Retinitis pigmentosa 85	Enrichment	AHR	2.63
7	Immunodeficiency 69	Enrichment	IFNG	2.63
8	Intellectual developmental disorder with speech delay, dysmorphic facies, and t-cell abnormalities	Enrichment	BCL11B	2.63
9	Immunodeficiency 130 with hpv-related verrucosis	Enrichment	IL7	2.63
10	Foveal hypoplasia 3	Enrichment	AHR	2.63
11	Allergic rhinitis	Enrichment	IL13	2.63
12	Immunodeficiency 29	Enrichment	IL12B	2.63
13	Type 1 diabetes mellitus 20	Enrichment	HNF1A	2.63
14	Immunodeficiency 88	Enrichment	TBX21	2.63
15	Microcephaly-polymicrogyria-corpus callosum agenesis syndrome	Enrichment	EOMES	2.63
16	Type 2 diabetes mellitus	Enrichment	HNF1A, IL6	2.36
17	Hypoparathyroidism, sensorineural deafness, and renal dysplasia syndrome	Enrichment	GATA3	2.33
18	Neutropenia, nonimmune chronic idiopathic, of adults	Enrichment	GFI1	2.33
19	Neutropenia, severe congenital, 2, autosomal dominant	Enrichment	GFI1	2.33
20	Immunodeficiency 127	Enrichment	TNF	2.33
21	B-lymphoblastic leukemia/lymphoma with hyperdiploidy	Enrichment	GATA3	2.33
22	Hypoparathyroidism-deafness-renal disease syndrome	Enrichment	GATA3	2.33
23	Intellectual developmental disorder with or without epilepsy or cerebellar ataxia	Enrichment	RORA	2.33
24	Autosomal dominant nonsyndromic deafness	Enrichment	GATA3	2.33
25	Hyperinsulinism due to hnf1a deficiency	Enrichment	HNF1A	2.33
26	Asthma, nasal polyps, and aspirin intolerance	Enrichment	TBX21	2.15
27	Takayasu arteritis	Enrichment	IL12B	2.15
28	Tuberous sclerosis 1	Enrichment	IFNG	2.15
29	Psoriatic arthritis	Enrichment	TNF	2.15
30	Hepatitis c virus	Enrichment	IFNG	2.15
31	Tuberous sclerosis 2	Enrichment	IFNG	2.15
32	Keratoderma-ichthyosis-deafness syndrome, autosomal recessive	Enrichment	HNF1A	2.15
33	Chromophobe renal cell carcinoma	Enrichment	HNF1A	2.15
34	Migraine without aura	Enrichment	TNF	2.15
35	End stage renal disease	Enrichment	GATA3	2.15
36	Kaposi sarcoma	Enrichment	IL6	2.03
37	Maturity-onset diabetes of the young, type 3	Enrichment	HNF1A	2.03
38	Cerebral malaria	Enrichment	TNF	2.03
39	Inherited epidermodysplasia verruciformis	Enrichment	IL7	2.03
40	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	2.03
41	Clear cell papillary renal cell carcinoma	Enrichment	HNF1A	2.03
42	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.93
43	Vascular dementia	Enrichment	TNF	1.93
44	Autosomal dominant severe congenital neutropenia	Enrichment	GFI1	1.93
45	Idiopathic aplastic anemia	Enrichment	IFNG	1.93
46	Clear cell renal cell carcinoma	Enrichment	HNF1A	1.85
47	Inflammatory bowel disease 1	Enrichment	IL6	1.68
48	Primary biliary cholangitis	Enrichment	IL12A	1.68
49	Aplastic anemia	Enrichment	IFNG	1.63
50	Combined immunodeficiency	Enrichment	BCL11B	1.59
51	Combined t cell and b cell immunodeficiency	Enrichment	BCL11B	1.59
52	Diabetes mellitus	Enrichment	HNF1A	1.59
53	Combined t and b cell immunodeficiency	Enrichment	BCL11B	1.59
54	Digeorge syndrome	Enrichment	HNF1A	1.55
55	Acute promyelocytic leukemia	Enrichment	ZBTB16	1.52
56	Alzheimer's disease	Enrichment	TNF	1.52
57	Renal cell carcinoma, nonpapillary	Enrichment	HNF1A	1.46
58	Human immunodeficiency virus type 1	Enrichment	IFNG	1.38
59	Arteriovenous malformations of the brain	Enrichment	IL6	1.36
60	Behcet syndrome	Enrichment	IL12A	1.36
61	Maturity-onset diabetes of the young	Enrichment	HNF1A	1.34
62	Malaria	Enrichment	TNF	1.28
63	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ZBTB16	1.28
64	Cakut	Enrichment	GATA3	1.11
65	Systemic lupus erythematosus	Enrichment	TNF	1.05
66	Gastric cancer	Enrichment	IL1B	1.01
67	Breast cancer	Enrichment	HNF1A	0.79
68	Ovarian cancer	Enrichment	HNF1A	0.67
69	Autism spectrum disorder	Enrichment	BCL11B	0.64
70	Microcephaly	Enrichment	BCL11B	0.60
71	Complex neurodevelopmental disorder	Enrichment	RORA	0.59
72	Retinitis pigmentosa	Enrichment	AHR	0.40

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Development and heterogeneity of the ILC family

Pathway Network for Development and heterogeneity of the ILC family

Member Pathways for Development and heterogeneity of the ILC family

Pathways in the Development and heterogeneity of the ILC family SuperPath

Associated Genes for Development and heterogeneity of the ILC family

Associated Disorders for Development and heterogeneity of the ILC family

Disorders associated with Development and heterogeneity of the ILC family SuperPath

STRING Interaction Network for Development and heterogeneity of the ILC family

Sources for Development and heterogeneity of the ILC family