Development_Glucocorticoid receptor signaling

No Pathway Network information available for Development_Glucocorticoid receptor signaling

Pathways in the Development_Glucocorticoid receptor signaling SuperPath

#	Name	Source	Genes
1	Development_Glucocorticoid receptor signaling	GeneGo (Thomson Reuters)	CEBPB CREBBP EP300 FKBP4 FOS HSP90AA1 HSP90AB1 HSP90B1 HSPA14 HSPA1A HSPA1B HSPA1L HSPA2 HSPA4 HSPA5 HSPA6 HSPA7 HSPA8 HSPA9 JUN MMP13 NCOA1 NCOA2 NFKB1 NFKB2 NFKBIA NR3C1 POU2F1 POU2F2 PTGES3 REL RELA RELB SERPINE1 SMAD3 STAT5A STAT5B SUMO1 TGFBR1 TRAP1 UBE2I (see all 41) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CEBPB	CCAAT Enhancer Binding Protein Beta	Protein Coding	1
2	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
3	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
4	FKBP4	FKBP Prolyl Isomerase 4	Protein Coding	1
5	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
6	NR3C1	Nuclear Receptor Subfamily 3 Group C Member 1	Protein Coding	1
7	HSPA1A	Heat Shock Protein Family A (Hsp70) Member 1A	Protein Coding	1
8	HSPA1B	Heat Shock Protein Family A (Hsp70) Member 1B	Protein Coding	1
9	HSPA1L	Heat Shock Protein Family A (Hsp70) Member 1 Like	Protein Coding	1
10	HSPA2	Heat Shock Protein Family A (Hsp70) Member 2	Protein Coding	1
11	HSPA4	Heat Shock Protein Family A (Hsp70) Member 4	Protein Coding	1
12	HSPA5	Heat Shock Protein Family A (Hsp70) Member 5	Protein Coding	1
13	HSPA6	Heat Shock Protein Family A (Hsp70) Member 6	Protein Coding	1
14	HSPA7	Heat Shock Protein Family A (Hsp70) Member 7 (Pseudogene)	Pseudogene	1
15	HSPA8	Heat Shock Protein Family A (Hsp70) Member 8	Protein Coding	1
16	HSPA9	Heat Shock Protein Family A (Hsp70) Member 9	Protein Coding	1
17	HSP90AA1	Heat Shock Protein 90 Alpha Family Class A Member 1	Protein Coding	1
18	HSP90AB1	Heat Shock Protein 90 Alpha Family Class B Member 1	Protein Coding	1
19	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
20	SMAD3	SMAD Family Member 3	Protein Coding	1
21	MMP13	Matrix Metallopeptidase 13	Protein Coding	1
22	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
23	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
24	NFKBIA	NFKB Inhibitor Alpha	Protein Coding	1
25	SERPINE1	Serpin Family E Member 1	Protein Coding	1
26	POU2F1	POU Class 2 Homeobox 1	Protein Coding	1
27	POU2F2	POU Class 2 Homeobox 2	Protein Coding	1
28	REL	REL Proto-Oncogene, NF-KB Subunit	Protein Coding	1
29	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	1
30	RELB	RELB Proto-Oncogene, NF-KB Subunit	Protein Coding	1
31	STAT5A	Signal Transducer And Activator Of Transcription 5A	Protein Coding	1
32	STAT5B	Signal Transducer And Activator Of Transcription 5B	Protein Coding	1
33	TGFBR1	Transforming Growth Factor Beta Receptor 1	Protein Coding	1
34	HSP90B1	Heat Shock Protein 90 Beta Family Member 1	Protein Coding	1
35	UBE2I	Ubiquitin Conjugating Enzyme E2 I	Protein Coding	1
36	SUMO1	Small Ubiquitin Like Modifier 1	Protein Coding	1
37	NCOA1	Nuclear Receptor Coactivator 1	Protein Coding	1
38	TRAP1	TNF Receptor Associated Protein 1	Protein Coding	1
39	NCOA2	Nuclear Receptor Coactivator 2	Protein Coding	1
40	PTGES3	Prostaglandin E Synthase 3	Protein Coding	1
41	HSPA14	Heat Shock Protein Family A (Hsp70) Member 14	Protein Coding	1

Disorders associated with Development_Glucocorticoid receptor signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Aortic aneurysm	Enrichment	SMAD3, TGFBR1	4.27
2	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	3.88
3	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	3.88
4	Common variable immunodeficiency	Enrichment	NFKB1, NFKB2	3.73
5	Loeys-dietz syndrome	Enrichment	SMAD3, TGFBR1	3.50
6	Rare genetic intellectual disability	Enrichment	CREBBP, EP300	3.04
7	Multiple self-healing squamous epithelioma	Enrichment	TGFBR1	2.52
8	Glucocorticoid resistance, generalized	Enrichment	NR3C1	2.52
9	Even-plus syndrome	Enrichment	HSPA9	2.52
10	Anemia, sideroblastic, 4	Enrichment	HSPA9	2.52
11	Growth hormone insensitivity syndrome with immune dysregulation 2, autosomal dominant	Enrichment	STAT5B	2.52
12	Immunodeficiency 92	Enrichment	REL	2.52
13	Orofacial cleft 10	Enrichment	SUMO1	2.52
14	Plasminogen activator inhibitor-1 deficiency	Enrichment	SERPINE1	2.52
15	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	2.52
16	Immunodeficiency 53	Enrichment	RELB	2.52
17	Menke-hennekam syndrome 1	Enrichment	CREBBP	2.52
18	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	2.52
19	Menke-hennekam syndrome	Enrichment	CREBBP	2.52
20	Congenital plasminogen activator inhibitor type 1 deficiency	Enrichment	SERPINE1	2.52
21	Galactosemia ii	Enrichment	NR3C1	2.22
22	Metaphyseal dysplasia, spahr type	Enrichment	MMP13	2.22
23	Thumb deformity	Enrichment	CREBBP	2.22
24	Growth hormone insensitivity syndrome with immune dysregulation 1, autosomal recessive	Enrichment	STAT5B	2.22
25	Spondyloepimetaphyseal dysplasia, missouri type	Enrichment	MMP13	2.22
26	Loeys-dietz syndrome 2	Enrichment	TGFBR1	2.22
27	Ectodermal dysplasia and immunodeficiency 2	Enrichment	NFKBIA	2.22
28	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.22
29	Immunodeficiency, common variable, 10	Enrichment	NFKB2	2.22
30	Loeys-dietz syndrome 3	Enrichment	SMAD3	2.22
31	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	2.22
32	Menke-hennekam syndrome 2	Enrichment	EP300	2.22
33	Rela fusion-positive ependymoma	Enrichment	RELA	2.22
34	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	2.22
35	Ectodermal dysplasia and immune deficiency	Enrichment	NFKBIA	2.22
36	Autosomal recessive sideroblastic anemia	Enrichment	HSPA9	2.22
37	Metaphyseal anadysplasia	Enrichment	MMP13	2.22
38	Common variable immunodeficiency 12	Enrichment	NFKB1	2.22
39	Laron syndrome with immunodeficiency	Enrichment	STAT5B	2.22
40	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SMAD3, TGFBR1	2.11
41	Nasopharyngeal carcinoma	Enrichment	NFKBIA	2.04
42	Tethered spinal cord syndrome	Enrichment	CREBBP	2.04
43	Loeys-dietz syndrome 1	Enrichment	TGFBR1	2.04
44	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	2.04
45	Immunodeficiency, common variable, 1	Enrichment	NFKB2	1.92
46	Congenital generalized lipodystrophy	Enrichment	FOS	1.92
47	Pseudomyogenic hemangioendothelioma	Enrichment	SERPINE1	1.92
48	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.82
49	Histiocytoid hemangioma	Enrichment	FOS	1.82
50	Congenital anomalies of kidney and urinary tract 1	Enrichment	TRAP1	1.74
51	Hypertrichosis	Enrichment	CREBBP	1.74
52	Classic ehlers-danlos syndrome	Enrichment	TGFBR1	1.74
53	Charge syndrome	Enrichment	EP300	1.57
54	Primary hyperaldosteronism	Enrichment	NR3C1	1.57
55	Familial thoracic aortic aneurysm and dissection	Enrichment	SMAD3	1.57
56	Marfan syndrome	Enrichment	TGFBR1	1.53
57	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.53
58	Pectus excavatum	Enrichment	TGFBR1	1.48
59	Acute promyelocytic leukemia	Enrichment	STAT5B	1.41
60	Aortic aneurysm, familial thoracic 1	Enrichment	SMAD3	1.38
61	Heart disease	Enrichment	CREBBP	1.38
62	Polydactyly, postaxial, type a1	Enrichment	EP300	1.35
63	Corpus callosum, agenesis of	Enrichment	CREBBP	1.35
64	Isolated corpus callosum agenesis	Enrichment	CREBBP	1.35
65	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP	1.35
66	Gliosarcoma	Enrichment	NFKBIA	1.33
67	Giant cell glioblastoma	Enrichment	NFKBIA	1.30
68	Diffuse large b-cell lymphoma	Enrichment	CREBBP	1.25
69	Ehlers-danlos syndrome	Enrichment	SMAD3	1.25
70	Tooth agenesis	Enrichment	SUMO1	1.19
71	Scoliosis	Enrichment	CREBBP	1.15
72	Connective tissue disease	Enrichment	SMAD3	1.03
73	Cakut	Enrichment	TRAP1	1.01
74	Myeloma, multiple	Enrichment	CREBBP	0.81
75	Autism	Enrichment	CREBBP	0.71
76	Breast cancer	Enrichment	JUN	0.69
77	Colorectal cancer	Enrichment	EP300	0.63
78	Congenital nervous system abnormality	Enrichment	CREBBP	0.56
79	Nervous system disease	Enrichment	CREBBP	0.56
80	Microcephaly	Enrichment	EP300	0.51

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Development_Glucocorticoid receptor signaling

Pathway Network for Development_Glucocorticoid receptor signaling

Member Pathways for Development_Glucocorticoid receptor signaling

Pathways in the Development_Glucocorticoid receptor signaling SuperPath

Associated Genes for Development_Glucocorticoid receptor signaling

Associated Disorders for Development_Glucocorticoid receptor signaling

Disorders associated with Development_Glucocorticoid receptor signaling SuperPath

STRING Interaction Network for Development_Glucocorticoid receptor signaling

Sources for Development_Glucocorticoid receptor signaling